scholarly journals Pengaruh Jenis Kelamin dan Kebiasaan Merokok terhadap Kadar Timbal Darah

2013 ◽  
pp. 164
Author(s):  
Wirsal Hasan ◽  
Abdul Rahim Matondang ◽  
Alvi Syahrin ◽  
Chatarina Umbul Wahyuni
Keyword(s):  
Blood Pressure ◽  
Pearson Correlation ◽  
Lead Level ◽  
Blood Lead ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Blood Lead Levels ◽  
Drinking Habits ◽  
Consecutive Sampling ◽  
Lead Levels

Penarik becak dayung dan becak bermesin, pengatur lalu lintas, pedagang asongan, dan pedagang kaki lima banyak terpapar dengan polusi timbal dari udara ambien yang merupakan ancaman terhadap para pekerja pinggir jalan. Penelitian ini bertujuan mengetahui hubungan karakteristik responden dengan kadar timbal dalam darah. Sampel dalam penelitian ini berjumlah 109 orang terdiri dari 58 orang penarik becak dayung, 30 orang penarik becak bermesin dan 21 orang pedagang kaki lima yang ditarik secara consecutive sampling. Hasil penelitian menunjukkan bahwa tidak ada korelasi yang signifikan antara variabel usia, tekanan darah sistolik dan tekanan darah diastolik terhadap kadar timbal dalam darah (p>0,05). Rerata kadar timbal dalam darah berbeda bermakna menurut jenis kelamin (p=0,047) dan kebiasaan merokok (p=0,003). Rerata kadar timbal dalam darah berdasarkan jenis pekerjaan, lama bekerja, tingkat pendidikan, tempat beristirahat, lokasi tempat tinggal, kebiasaan minum susu, dan kebiasaan minum alkohol tidak ada perbedaan bermakna. Uji korelasi Pearson dan korelasi Spearman menemukan tidak ada korelasi antara variabel usia dan tekanan darah terhadap kadar timbal dalam darah (p>0,05).Paddle rickshaw puller, motorized rickshaw pullers, traffic police, street vendors and roadside vendors is that many workers are exposed to lead from ambient air pollution. Lead pollution is a threat to roadside workers. This study is observational. The purpose of the study was to determine the association between respondent characteristic with blood lead levels. The 109 samples in this study was the 58 paddle rickshaw puller, 30 motorized rickshaw pullers and 21 hawkers, drawn with consecutive sampling. The results showed that there were no significant correlation between age, blood pressure and blood lead level (p>0.005), there were differences in mean blood lead levels by sex (p = 0.047) and smoking (p = 0.003), there was no difference in mean blood lead levels based on the type of work, length of work, level of education, place of rest, the location shelter, drinking milk, and alcohol drinking habits. Pearson correlation test and Spearman correlation found no correlation between the variables of age, and blood pressure on blood lead levels (p> 0.05).

scholarly journals Blood lead level and risk of hypertension in the United States National Health and Nutrition Examination Survey 1999–2016

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Man Fung Tsoi ◽  
Chris Wai Hang Lo ◽  
Tommy Tsang Cheung ◽  
Bernard Man Yung Cheung
Keyword(s):  
Blood Pressure ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
The United States ◽  
Study Data ◽  
Blood Lead Levels ◽  
Environmental Lead ◽  
Lead Levels

AbstractLead is a heavy metal without a biological role. High level of lead exposure is known to be associated with hypertension, but the risk at low levels of exposure is uncertain. In this study, data from US NHANES 1999–2016 were analyzed. Adults with blood lead and blood pressure measurements, or self-reported hypertension diagnosis, were included. If not already diagnosed, hypertension was defined according to the AHA/ACC 2017 hypertension guideline. Results were analyzed using R statistics version 3.5.1 with sample weight adjustment. Logistic regression was used to study the association between blood lead level and hypertension. Odds ratio (OR) and 95% confidence interval (95% CI) were estimated. Altogether, 39,477 participants were included. Every doubling in blood lead level was associated with hypertension (OR [95%CI] 1.45 [1.40–1.50]), which remained significant after adjusting for demographics. Using quartile 1 as reference, higher blood lead levels were associated with increased adjusted odds of hypertension (Quartile 4 vs. Quartile 1: 1.22 [1.09–1.36]; Quartile 3 vs. Quartile 1: 1.15 [1.04–1.28]; Quartile 2 vs. Quartile 1: 1.14 [1.05–1.25]). In conclusion, blood lead level is associated with hypertension in the general population with blood lead levels below 5 µg/dL. Our findings suggest that reducing present levels of environmental lead exposure may bring cardiovascular benefits by reducing blood pressure.

scholarly journals Correlation of Blood Lead Levels and Elevated Blood Pressure in Newly Detected Hypertensive Patients

2021 ◽  
Vol 10 (13) ◽  
pp. 941-946
Author(s):  
Shuaib Ahmed M. A ◽  
Raghav Sharma ◽  
Shama Prakash K
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Lead Level ◽  
Blood Lead ◽  
Health Concern ◽  
Blood Lead Levels ◽  
P Value ◽  
Hypertensive Patients ◽  
Lead Levels

BACKGROUND Hypertension is one of the most common diseases all over the world. Lead is a common environmental and industrial pollutant with no beneficial biological role. The contribution of environmental lead exposure to hypertension is an important public health concern. The objective of this study was to determine the blood lead levels in hypertensive patients and to investigate the correlation between blood lead (B-Pb) levels and the values of blood pressure in hypertensive patients. METHODS This is a hospital based analytical cross-sectional study conducted over a period of one and half years. Subjects included 50 newly detected hypertensive and 50 healthy subjects recruited who were both age and sex matched. Mean of age, blood lead levels, systolic blood pressure (SBP), diastolic blood pressure (DBP) with standard deviation were assessed. Linear regression was used to estimate the predicted systolic blood pressure (BP) and diastolic BP with lead levels. Pearson correlation was used to estimate the correlation between blood lead and blood pressure levels. RESULTS In this study, 52 % of cases and controls were in the age group of 41 - 60 years. 22 % of the subjects were more than 61 years of age. 45 % of the total subjects were females and 55 % were males. 46 % of the controls and 44 % of the cases were females. Comparison of the serum lead levels (mcg / dl) between cases and controls showed that serum lead levels (mcg / dl) were higher in Cases group with a t-value of -7.38 and was statistically significant with a P-value of < 0.001. Comparison of the serum lead levels (mcg / dl) between the males and females showed that serum lead levels (mcg / dl) were higher in female group with a t-value of - 0.151 and was statistically non-significant with a P-value of 0.881. This study showed that there is an increase in blood lead levels in hypertensive patients compared to the control group. Stage 2 hypertension has higher serum lead level value of 21.228 compared to stage 1. Serum lead levels were higher in females compared to males. CONCLUSIONS Our study indicated that blood lead level is significantly and positively correlated to blood pressure among newly detected hypertensive patients. Increase in blood lead levels causes increase in both systolic and diastolic blood pressures. KEY WORDS Hypertension, Lead, Systolic Blood Pressure, Diastolic Blood Pressure

Hardness of Domestic Water and Blood Lead Levels

1983 ◽  
Vol 2 (4) ◽  
pp. 645-648 ◽  
Author(s):  
P.C. Elwood ◽  
K.M. Phillips ◽  
N. Lowe ◽  
J.K. Phillips ◽  
C. Toothill
Keyword(s):  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Hard Water ◽  
Control Area ◽  
Blood Lead Levels ◽  
Domestic Water ◽  
Solvent Water ◽  
Small Rise ◽  
Lead Levels

1 The effect on the blood lead levels of residents in an area in which a soft plumbo-solvent water was hardened is examined. 2 Water lead levels fell after hardening was introduced whereas there was a small rise in water lead levels in a control area monitored over the same time. 3 The blood lead levels of residents fell after hardening and the fall was slightly greater than would have been predicted on the basis of the change in water lead levels. This suggests that lead is less well absorbed from hard water than from soft water. 4 Following hardening there was a significant fall in mean blood lead level of subjects living in houses which had initially had negligible amounts of lead in the water. This suggests that hard water may interfere with the absorption of lead from sources other than water.

High Lead Exposure Associated With Higher Blood Pressure in Haiti: a Warning Sign for Low-Income Countries

Hypertension ◽  
2021 ◽  
Author(s):  
Lily D. Yan ◽  
Vanessa Rouzier ◽  
Jean Lookens Pierre ◽  
Myung Hee Lee ◽  
Paul Muntner ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Lead Exposure ◽  
Lead Level ◽  
Blood Lead ◽  
Lower Income ◽  
Environmental Lead ◽  
Lead Levels ◽  
Environmental Lead Exposure ◽  
Lower Income Countries

Cardiovascular disease is the leading cause of death in lower-income countries including Haiti. Environmental lead exposure is associated with high blood pressure and cardiovascular mortality in high-income countries but has not been systematically measured and evaluated as a potential modifiable cardiovascular risk factor in lower-income countries where 6.5 billion people reside. We hypothesized lead exposure is high in urban Haiti and associated with higher blood pressure levels. Blood lead levels were measured in 2504 participants ≥18 years enrolled in a longitudinal population-based cohort study in Port-au-Prince. Lead screening was conducted using LeadCare II (detection limit ≥3.3 µg/dL). Levels below detection were imputed by dividing the level of detection by √2. Associations between lead (quartiles) and systolic blood pressure and diastolic blood pressure were assessed, adjusting for age, sex, obesity, smoking, alcohol, physical activity, income, and antihypertensive medication use. The median age of participants was 40 years and 60.1% were female. The geometric mean blood lead level was 4.73µg/dL, 71.1% had a detectable lead level and 42.3% had a blood lead level ≥5 µg/dL. After multivariable adjustment, lead levels in quartile four (≥6.5 µg/dL) compared with quartile 1 (<3.4 µg/dL) were associated with 2.42 mm Hg (95% CI, 0.36–4.49) higher systolic blood pressure and 1.96 mm Hg (95% CI, 0.56–3.37) higher diastolic blood pressure. In conclusion, widespread environmental lead exposure is evident in urban Haiti, with higher lead levels associated with higher systolic and diastolic blood pressure. Lead is a current and potentially modifiable pollutant in lower-income countries that warrants urgent public health remediation. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03892265.

Blood Lead Screening Practices Among US Pediatricians

PEDIATRICS ◽  
1996 ◽  
Vol 98 (3) ◽  
pp. 372-377
Author(s):  
James R. Campbell ◽  
Stanley J. Schaffer ◽  
Peter G. Szilagyi ◽  
Karen G. O'Connor ◽  
Peter Briss ◽  
...  
Keyword(s):  
Primary Care ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Elevated Blood ◽  
Control And Prevention ◽  
Lead Levels ◽  
Primary Care Pediatricians ◽  
Elevated Blood Lead Levels

Objectives. In 1991, the Centers for Disease Control and Prevention (CDC) decreased the blood lead level of concern to 10 µg/dL (0.48 µmol/L) and recommended universal screening. Because these guidelines continue to provoke controversy, we conducted a study to:1) estimate the proportion of pediatricians who are members of the American Academy of Pediatrics (AAP) who report screening for elevated blood lead levels; 2) describe their clinical practices regarding screening for elevated blood lead levels; 3) compare attitudes of universal screeners, selective screeners, and nonscreeners; and 4) identify characteristics of pediatricians who universally screen. Design. Confidential, cross-sectional survey of a nationally representative random sample of 1610 pediatricians conducted through the AAP Periodic Survey. Subjects. The study included 1035 responders (64% response rate). Analysis was limited to the 734 pediatricians who provide well-child care (ie, primary-care pediatricians). Results. Fifty-three percent of pediatricians reported screening all their patients aged 9 to 36 months, 39% reported screening some, and 8% reported screening none. Among those who screen, 96% use a blood lead assay. The primary risk factors for which selective screeners screen are: history of pica (94%); living in an older home with recent renovations (92%); living in an older home with peeling paint (93%); and having a sibling who had an elevated blood lead level (88%). Among primary-care pediatricians, 73% agree that blood lead levels ≥10 µg/dL should be considered elevated, and 16% disagree. However, 89% of primary-care pediatricians believe that epidemiologic studies should be performed to determine which communities have high proportions of children with elevated blood lead levels, and 34% of primary-care pediatricians believe that the costs of screening exceed the benefits. Conclusions. Three years after the Centers for Disease Control and Prevention issued new guidelines for the management of elevated blood lead levels, a slight majority of primary-care pediatricians in the United States who are members of the AAP report that they universally screen their appropriately aged patients, while most of the remaining pediatricians report screening high-risk patients. Many pediatricians may want additional guidance about circumstances under which selective screening should be considered.

scholarly journals Against lead poisoning: effectiveness of housing first and counselling in the home

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
R Laporte ◽  
H Barberin de Barberini ◽  
E Jouve ◽  
K Hadji ◽  
S Gentile
Keyword(s):  
Lead Poisoning ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Housing First ◽  
Blood Lead Levels ◽  
Stable Housing ◽  
Lead Levels

Abstract Background Removing lead sources is the main measure against child lead poisoning. Medical treatment is ineffective for most mild cases and particularly against long-term complications in neurological development. However, the effectiveness of interventions to eliminate sources of lead exposure has not been fully established, mainly because of the diversity of situations. The objective of this study was to determine the influence of several interventions (housing counselling, rehabilitation and relocation) on blood lead levels in two situations (stable unhealthy housing with old flaked lead paints, slums with family recycling practices by incineration). Methodology A historical cohort of lead poisoning in children has been established in Marseille, France. Medical follow-up followed national guidelines. Environmental interventions followed legal procedures, where available. In slums, counselling was adapted to the exposure. A generalized mixed model was developed to study the kinetics of blood lead levels after the interventions. Results 151 children were included; age = 5.4 (SD = 7.8) years; 85 (56%) lived in stable unhealthy housing, others lived in slums. Medical follow-up included 492 blood lead levels. For children living in stable unhealthy housing, blood lead level decrease was significantly associated with every intervention: housing counselling, rehabilitation and relocation (respectively p &lt; 0.005; p &lt; 0.05 and p &lt; 0.005). For children living in slums, blood lead level decrease was only associated with relocation in a stable housing (p &lt; 0.005). Conclusions Several interventions are effective to decrease blood lead levels in unhealthy housing. In slums, access to a stable housing first is a prerequisite for any intervention against child lead poisoning, even when related to family practices. Key messages In stable unhealthy housing, several interventions against lead exposure can be effective to raise a strategy. But, environmental health and access to housing first needs to be addressed for their implementation.

scholarly journals Blood Levels of the Heavy Metal, Lead, and Caries in Children Aged 24-72 Months: NHANES III

2014 ◽  
Vol 49 (1) ◽  
pp. 26-33 ◽  
Author(s):  
R. Constance Wiener ◽  
D. Leann Long ◽  
Richard J. Jurevic
Keyword(s):  
Negative Binomial ◽  
Strong Association ◽  
Lead Level ◽  
Negative Binomial Regression ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Nhanes Iii ◽  
Blood Levels ◽  
Lead Levels ◽  
Using Data

Lead remains a significant pollutant. It has acute toxic and chronic effects on many tissues and accumulates in teeth and bones. The researchers for this study investigated the association of blood lead levels with the extent/severity of caries as measured by the number of decayed/filled teeth of children aged 24-72 months using data from NHANES III (the Third National Health and Nutrition Examination Survey), accounting for the excess zero caries in the analysis and using less than 2 µg/dl as the reference blood lead level (n = 3,127). Zero-inflated negative binomial regression models indicated unadjusted extent/severity mean ratios of 1.79, 1.88 and 1.94 for the number of decayed/filled teeth in children whose blood lead levels were 2-5, 5-10 and >10 µg/dl, respectively, compared with children having <2 µg/dl blood lead levels. The results did not attenuate when other variables were added to the model for the 5-10 and >10 µg/dl levels of exposure. The adjusted extent/severity mean ratios were 1.84, 2.14 and 1.91, respectively, for the categories. This study indicated a strong association of blood lead levels with increasing numbers of carious teeth in children aged 24-72 months. These findings support other studies in an innovative analysis handling cases of children with no caries. The findings may inform caries risk assessment. © 2014 S. Karger AG, Basel

scholarly journals Proximity of residence to an old mineral storage site in Chile and blood lead levels in children

2016 ◽  
Vol 32 (4) ◽  
Author(s):  
Loreto Lisboa ◽  
José Klarián ◽  
Rosario Toro Campos ◽  
Verónica Iglesias
Keyword(s):  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Outcome Variable ◽  
Blood Lead Levels ◽  
Storage Site ◽  
Inverse Association ◽  
Cross Sectional ◽  
Exposure Variable ◽  
Lead Levels

Evidence suggests that an old mineral storage site removed in 1998 due to high lead content, remains as a source of exposure in the city of Antofagasta, Chile. The aim was to determine the association between blood lead levels in children and the residential proximity to the old mineral storage site. A cross sectional study was conducted with 185 children aged 7 to 16 years. The outcome variable was blood lead levels measured in 2005. The exposure variable was the distance between the current residence and the old mineral storage site. The distance was measured in meters by Geographic Information System (GIS). The median blood lead level in 2005 was 3.3μg/dL (interquartile range ‒ IQR: 2.0-4.3). A significant inverse association was found between the residential distance to the old mineral storage site and the blood lead levels in children, after adjusting by confounders (β: -0.04; 95%CI: -0.09; -0.01). This result suggests that the old mineral storage site continues to be a source of lead exposure for the children living nearby.

Predicting the Children's Blood Lead Level in a Lead and Zinc Smelting Area Based on IEUBK Model

2015 ◽  
Vol 1092-1093 ◽  
pp. 687-691
Author(s):  
Fei Chen ◽  
Hong Guang Cheng ◽  
Xiang Fen Cui
Keyword(s):  
Lead Concentration ◽  
Lead Level ◽  
Blood Lead ◽  
Blood Lead Concentration ◽  
Blood Lead Levels ◽  
Prediction Ability ◽  
Environmental Lead ◽  
Lead And Zinc ◽  
Zinc Smelting ◽  
Lead Levels

According to environmental lead exposure data and dietary survey data of lead and zinc smelting area,blood lead levels of children (2~7years old) in study area were predicted with IEUBK model. The children's blood lead concentration predicted value was compared with the corresponding measured value,by comparing the differences, measured the prediction ability of model. The results showed that predicted value and measured value of 2~7 years old children's blood lead concentration in A village were higher than the other villages, they were 33.5μg/dL,30.8μg/dL, respectively; predicted value and measured value of 2~7 years old children's blood lead concentration in I village were the lowest among all villages,they were14.5μg/dL,13.1μg/dL, respectively.By paired T-test showed that the predicted value were higher than the measured value about 1.4~3.4μg/dL,model calculation results slightly overestimated the children's blood lead level.But in general, the predicted value and measured value had a good consistency,through the model prediction could better reflect the children's blood lead levels in the study area.

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