Kinetic- spectrophotometric Method for the Determination of Naringenin in Pure and Supplements Formulations

Simple, cheap, sensitive, and accurate kinetic- spectrophotometric method has been developed for the determination of naringenin in pure and supplements formulations. The method is based on the formation of Prussian blue. The product dye exhibits a maximum absorbance at 707 nm. The calibration graph of naringenin was linear over the range 0.3 to 10 µg ml-1 for the fixed time method (at 15 min) with a correlation coefficient (r) and percentage linearity (r2%) were of 0.9995 and 99.90 %, respectively, while the limit of detection LOD was 0.041 µg ml-1. The method was successfully applied for the determination of naringenin in supplements with satisfactory results.

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The Development of a New Kinetic Spectrophotometric Method for the Determination of Vanadium(V) Based on its Catalytic Effect on the Oxidation of Malachite Green Oxalate by Bromate in Acidic and Micellar Medium

E-Journal of Chemistry ◽

10.1155/2010/683069 ◽

2010 ◽

Vol 7 (4) ◽

pp. 1612-1620 ◽

Cited By ~ 4

Author(s):

M. Keyvanfard ◽

N. Abedi

Keyword(s):

Malachite Green ◽

Spectrophotometric Method ◽

Catalytic Effect ◽

Limit Of Detection ◽

Fixed Time ◽

Micellar Medium ◽

Relative Standard ◽

Kinetic Spectrophotometric ◽

Malachite Green Oxalate

A new, simple, sensitive and selective kinetic spectrophotometric method was developed for the determination of ultra trace amounts of vanadium(V). The method is based on the catalytic effect of vanadium(V) on the oxidation of malachite green oxalate (MG) by bromate in acidic and micellar medium. The reaction was monitored spectrophotometrically by measuring the decrease in the absorbance of malachite green oxalate (MG) at 625 nm with a fixed-time method. The decrease in the absorbance of MG is proportional to the concentration of vanadium(V) in the range of 1-100 ng/mL with a fixed time of 0.5-2 min from the initiation of the reaction. The limit of detection is 0.71 ng/mL of vanadium(V). The relative standard deviation for the determination of 5, 30, 50 ng/mL of vanadium(V) was2.5% 2.6%, 2.4% and respectively. The method was applied to the determination of vanadium(V) in water samples.

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Kinetic Spectrophotometric Determination of Ruthenium by its Catalytic Effect on the Reduction of Spadns with Sodium Hypophosphite in Micellar Media

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.204-208.4067 ◽

2012 ◽

Vol 204-208 ◽

pp. 4067-4070 ◽

Cited By ~ 1

Author(s):

Zhi Rong Zhou ◽

Li Zhen Zhang

Keyword(s):

Standard Deviation ◽

Spectrophotometric Method ◽

Catalytic Effect ◽

Limit Of Detection ◽

Fixed Time ◽

Sodium Hypophosphite ◽

Micellar Media ◽

Relative Standard ◽

Kinetic Spectrophotometric

A simple kinetic spectrophotometric method was developed for the determination of trace amounts of Ru (III). The method is based on the reduction of spadns by sodium hypophosphite (NaH2PO2) in micellar media. The reaction was monitored spectrophotometrically by measuring the decrease in the absorbance of spadns at 515 nm with a fixed-time method. The decrease in the absorbance of spadns is proportional to the concentration of Ru (III) in the range 0.40–10.0 μg/L with a fixed time of 2.5–7.0 min from the initiation of the reaction. The limit of detection is 0.12 μg/L Ru (III). The relative standard deviation for the determination of 0.10 and 0.20 μg/25mL Ru (III) was 2.3 % and 2.0 %, respectively. The method was applied to the determination of Ru (III) in some ores and metallurgy products.

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Kinetic Spectrophotometric Method for Determination of Vanadium in Syrian Oil Using 1,5-Diphenylcarbazide Reagent

International Letters of Chemistry Physics and Astronomy ◽

10.18052/www.scipress.com/ilcpa.67.42 ◽

2016 ◽

Vol 67 ◽

pp. 42-49 ◽

Cited By ~ 1

Author(s):

Issa Moustafa ◽

Mouhammed Khateeb ◽

Obaida Alhamed

Keyword(s):

Crude Oil ◽

Spectrophotometric Method ◽

Limit Of Detection ◽

Statistical Treatment ◽

Fixed Time ◽

Buffer Solution ◽

Colored Complex ◽

Heavy Product ◽

Kinetic Spectrophotometric

New, sensitive, accurate and inexpensive kinetic spectrophotometric method was developed and validated for the determination of V(V) in crude oil and its heavy product. The method is based on the formation of colored complex between V(V) and 1, 5-diphenylcarbazide (DPCI). The method involves the reaction of V(V) with DPCI in presence of buffer solution of pH 6.8 to form colored complex with λmax at 530 nm. The fixed time method (2000 Sec) was adopted for constructing the calibration curve. The linearity range was found to be (2-12) mg/L. The correlation coefficient was 0.9999 and the limit of detection was found to be 0.349 mg/L. The method is feasible with the calibration equations obtained, which makes this method more applicable. Statistical treatment of the experimental results indicates that the method is precise, selective and accurate. The method was successfully applied for determination of V(V) in Syrian crude oil and its heavy product.

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A Simple and Sensitive Spectrophotometric Method for the Determination of Trace Ruthenium with its Catalytic Effect on the Oxidation of Rhodamine 6G by KBrO3 in Micellar Media

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.217-219.2397 ◽

2012 ◽

Vol 217-219 ◽

pp. 2397-2401 ◽

Cited By ~ 1

Author(s):

Zhi Rong Zhou ◽

Li Zhen Zhang

Keyword(s):

Spectrophotometric Method ◽

Catalytic Effect ◽

Rhodamine 6G ◽

Limit Of Detection ◽

Fixed Time ◽

Micellar Media ◽

Relative Standard ◽

Kinetic Spectrophotometric ◽

Sensitive Spectrophotometric Method

A simple catalytic kinetic spectrophotometric method was developed for the determination of trace Ru (III) in the range of 0.033–1.00 μg/L. The method is based on the catalytic effect of Ru (III) on the oxidation of rhodamine 6G (Rh 6G) by bromate in micellar media. The reaction was monitored spectrophotometrically by measuring the decrease in the absorbance of Rh 6G at 520 nm with a fixed-time method. The limit of detection is 0.010 μg/L Ru (III). The relative standard deviation for the determination of 0.010 and 0.020 μg/25mL Ru (III) was 2.9 % and 2.5 %, respectively. The method was applied to the determination of Ru (III) in some ores and metallurgy products.

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New Kinetic Spectrophotometric Method for Determination of Folic Acid in Pharmaceutical Formulations

International Letters of Chemistry Physics and Astronomy ◽

10.18052/www.scipress.com/ilcpa.50.169 ◽

2015 ◽

Vol 50 ◽

pp. 169-178

Author(s):

Mouhammed Khateeb ◽

Basheer Elias ◽

Fatema Al Rahal

Keyword(s):

Folic Acid ◽

Spectrophotometric Method ◽

Pharmaceutical Formulations ◽

Fixed Time ◽

Rate Data ◽

Sulfuric Acid Medium ◽

Significant Difference ◽

Kinetic Spectrophotometric ◽

Comparison Of The Results

A simple and sensitive kinetic spectrophotometric method has been developed for the determination of folic acid (FA) in bulk and pharmaceutical Formulations. The method is based on the oxidation of FA by Fe (III) in sulfuric acid medium. Fe (III) subsequently reduces to Fe (II) which is coupled with potassium ferricyanide to form Prussian blue. The reaction is followed spectrophotometrically by measuring the increase in absorbance at λmax 725 nm. The rate data and fixed time methods were adopted for constructing the calibration curves. The linearity range was found to be 1–20 μg mL-1 for each method. The correlation coefficient was 0.9978 and 0.9993, and LOD was found to be 0.91 and 0.09 μg mL-1 for rate data and fixed time methods, respectively. The proposed method has been successfully applied to the determination of FA in formulations with no interference from the excipients. Statical comparison of the results shows that there is no significant difference between the proposed and pharmacopoeial methods

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Determination of Sodium Cromoglycate by a New Kinetic Spectrophotometric Method in Biological Samples

Journal of Chemistry ◽

10.1155/2013/206784 ◽

2013 ◽

Vol 2013 ◽

pp. 1-5

Author(s):

Mohsen Keyvanfard ◽

Khadijeh Alizad ◽

Razieh Shakeri

Keyword(s):

Standard Deviation ◽

Sodium Cromoglycate ◽

Spectrophotometric Method ◽

Calibration Curve ◽

Biological Samples ◽

Limit Of Detection ◽

Micellar Medium ◽

Relative Standard ◽

Kinetic Spectrophotometric

A new kinetic spectrophotometric method is described for the determination of ultratrace amounts of sodium cromoglycate (SCG). The method based on catalytic action of SCG on the oxidation of amaranth with periodate in acidic and micellar medium. The reaction was monitored spectrophotometrically by measuring the decrease in absorbance of the amaranth at 518 nm, for the first 4 min from initiation of the reaction. Calibration curve was linear in the range of 4.0−36.0 ng mL−1SCG. The limit of detection is 2.7 ng mL−1SCG. The relative standard deviation (RSD) for ten replicate analyses of 12, 20, and 28 ng mL−1SCG was 0.40%, 0.32%, and 0.53%, respectively. The proposed method was used for the determination of SCG in biological samples.

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Kinetic Spectrophotometric Method for the Determination of Selenium (IV) by its Catalytic Effect on the Reduction of Arsenazo III with Sodium Hypophosphite in Micellar Media

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.554-556.926 ◽

2012 ◽

Vol 554-556 ◽

pp. 926-933

Author(s):

Zhi Rong Zhou ◽

Li Zhen Zhang

Keyword(s):

Standard Deviation ◽

Relative Standard Deviation ◽

Spectrophotometric Method ◽

Catalytic Effect ◽

Fixed Time ◽

Sodium Hypophosphite ◽

Micellar Media ◽

Relative Standard ◽

Kinetic Spectrophotometric

A simple and sensitive kinetic spectrophotometric method for the determination of trace selenium (IV) is described, based on its catalytic effect on the reduction arsenazo III (AsA III) with sodium hypophosphite (NaH2PO2) in a solution of 0.02 mol/L sulfuric acid and in the presence of cationic micellar media. The reaction rate is monitored spectrophotometrically by measuring the decrease in absorbance of AsA III at 550 nm with a fixed-time method. The decrease in the absorbance of AsA III is proportional to the concentration of Se(IV) in the range 0.16–1.0 µg/L after a fixed time of 4–10 min from the initiation of the reaction. The limit of detection is 0.049 µg/L Se(IV). The influence of th e factors such as acidity, concentration of reactants, type and concentration of surfactants, reactive time, temperature and co-existing ions on the reaction is discussed. The optimum reaction conditions of reaction are established and some kinetic parameters are determined; the apparent activation energy of catalytic reaction is 59.51 kJ/mol. The relative standard deviation for eleven replicate determination of 0.02, and 0.01µg/25mL Se(IV) was 2.0 % and 2.4 %, respectively. Combined with sulphydryl dextrane gel (SDG) separation and enriching, the method has been successfully applied to the determination of Se (IV) in foodstuff and human hair samples with the relative standard deviation of 2.1 %–5.8 % and the recovery of 97.0 %–103.3 %, the results are in good agreement with those provided by ICP-AES method.

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A New Kinetic Spectrophotometric Method for the Quantitation of Amorolfine

Journal of Analytical Methods in Chemistry ◽

10.1155/2017/9812894 ◽

2017 ◽

Vol 2017 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

César Soto ◽

Cristian Poza ◽

David Contreras ◽

Jorge Yáñez ◽

Fallon Nacaratte ◽

...

Keyword(s):

Spectrophotometric Method ◽

Tap Water ◽

Fixed Time ◽

Fungal Cell ◽

Inhibition Of Growth ◽

Fungicide Activity ◽

Dual Inhibition ◽

Assay Precision ◽

Kinetic Spectrophotometric

Amorolfine (AOF) is a compound with fungicide activity based on the dual inhibition of growth of the fungal cell membrane, the biosynthesis and accumulation of sterols, and the reduction of ergosterol. In this work a sensitive kinetic and spectrophotometric method for the AOF quantitation based on the AOF oxidation by means of KMnO4at 30 min (fixed time), pH alkaline, and ionic strength controlled was developed. Measurements of changes in absorbance at 610 nm were used as criterion of the oxidation progress. In order to maximize the sensitivity, different experimental reaction parameters were carefully studied via factorial screening and optimized by multivariate method. The linearity, intraday, and interday assay precision and accuracy were determined. The absorbance-concentration plot corresponding to tap water spiked samples was rectilinear, over the range of 7.56 × 10−6–3.22 × 10−5 mol L−1, with detection and quantitation limits of 2.49 × 10−6 mol L−1and 7.56 × 10−6 mol L−1, respectively. The proposed method was successfully validated for the application of the determination of the drug in the spiked tap water samples and the percentage recoveries were 94.0–105.0%. The method is simple and does not require expensive instruments or complicated extraction steps of the reaction product.

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Kinetic Spectrophotometric Determination of Gemifloxacin Mesylate and Moxifloxacin Hydrochloride in Pharmaceutical Preparations Using 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole

Journal of Spectroscopy ◽

10.1155/2014/917234 ◽

2014 ◽

Vol 2014 ◽

pp. 1-12 ◽

Cited By ~ 2

Author(s):

Mohammed G. Abdel Wahed ◽

Ragaa El Sheikh ◽

Ayman A. Gouda ◽

Sayed Abou Taleb

Keyword(s):

Limit Of Detection ◽

Kinetic Method ◽

Pharmaceutical Preparations ◽

Fixed Time ◽

Spectrophotometric Methods ◽

Relative Standard ◽

Significant Difference ◽

Kinetic Spectrophotometric ◽

Comparison Of The Results

Simple, sensitive, and accurate kinetic spectrophotometric method was proposed for the determination of gemifloxacin mesylate (GMF) and moxifloxacin hydrochloride (MOX) in pure forms and pharmaceutical preparations (tablets). The method is based on coupling the studied drugs with 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) in the presence of alkaline borate buffer. Spectrophotometric measurement was achieved by recording the absorbance at 466 and 464 nm for GMF and MOX, respectively, after a fixed time of 20 and 15 min on a water bath adjusted at 70 ± 5°C for both drugs. The different experimental parameters affecting the development and stability of the color were carefully studied and optimized. The absorbance-concentration plots were linear over the ranges 0.5–8.0 and 2.0–12 μg mL−1for GMF and MOX, respectively. The limit of detection of the kinetic method was about 0.12 (2.47 × 10−7 M) and 0.36 (8.22 × 10−7 M) μg mL−1for GMF and MOX, respectively. The proposed methods have been applied and validated successfully with percentage relative standard deviation (RSD% ≤ 0.52) as precision and percentage relative error (RE% ≤ 1.33) as accuracy. The robustness of the proposed method was examined with recovery values that were 97.5–100.5 ± 1.3–1.9%. Statistical comparison of the results with the reference spectrophotometric methods shows excellent agreement and indicates no significant difference in accuracy or precision.

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Determination of CLINDAMYCIN HCl in Capsules by New, Validated, Simple and Green Kinetic Spectrometric Method

10.21203/rs.3.rs-199417/v1 ◽

2021 ◽

Author(s):

Shaza Affas ◽

Amir Alhaj Sakur

Keyword(s):

Initial Rate ◽

Limit Of Detection ◽

Reference Method ◽

Fixed Time ◽

Spectrometric Method ◽

Iodide Ions ◽

Kinetic Spectrophotometric ◽

Optimized Conditions ◽

Good Agreement

Abstract Background: simple, sensitive, free of organic solvents, kinetic spectrophotometric method has been developed for the determination of Clindamycin Hydrochloride, both in pure form and Capsules. Method used is based on reaction of Clindamycin with potassium iodide and potassium iodate in aqueous medium at (25 ±2 °c) to produce yellow colored tri iodide ions (I3-). the reaction is followed spectrophotometrically by measuring the absorbance at 350 nm wavelength during 40 minutes. Results: the effects of analytical parameters on reported kinetic methods were investigated. Under the optimized conditions, the initial rate and fixed time (at 10 min) methods were used for constructing the calibration graphs. The graphs were linear in concentration ranges 1-20 μg.ml-1 with limit of detection of 0.12 and 0.22 μg ml-1for the initial rate and fixed time methods, respectively. The results were satisfactory and the analytical performance for both methods was validated. Conclusion: The proposed methods have been applied to determine the components in capsules with an average recovery of 98.25% to 102.00% and the results are in good agreement with those found by the reference method.

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