scholarly journals Development of Adrenocorticotrophic Hormone Cells of Adenohypophysis–Adrenal Cortex Axis of Long-tailed Monkey (Macaca fascicularis) during Pre and Postnatal Period

Author(s):  
Nurhidayat Nurhidayat ◽  
Ika K. Syarifah ◽  
Supratikno Supratikno ◽  
Sri Wahyuni

The objective of this study is to observe the relationship of development of adrenocorticotropic hormone (ACTH) cells of adenohypophysis–adrenal cortex axis during pre and postnatal period of longtailed monkey (Macaca fascicularis). Five fetuses aged 70, 85, 100, 120, and 150 days of gestation and 2new born aged 10 and 105 days old were used as research materials. The sections of the pituitary gland stained immunohistochemically using human ACTH antiserum and the adrenal glands stained by Hematoxylin-Eosin procedures. At the fetus 120 days old, the ACTH cells and blood vessel of fetaladenohypophysis developed well and its similar that found in older age. This condition suggested distributing the ACTH to whole body optimally. At the same time, the adrenal cortex cells of fetus 120 days old were active in proliferation and differentiation processes to form transition zone that lies between definitive and fetal zones, and central vein also developed in adrenal gland. In fetus aged 150 days, the cortex adrenal structure was similar with found in older fetus. The adenohypophysis ACTH cells developed earlier than adrenal cortex and their secretion suggested influencing the development of adrenal cortex cells of long-tailed monkey.

Blood ◽  
1948 ◽  
Vol 3 (7) ◽  
pp. 729-754 ◽  
Author(s):  
WILLIAM N. VALENTINE ◽  
CHARLES G. CRADDOCK ◽  
JOHN S. LAWRENCE

Abstract The hormonal control through the hypophyseo-adrenal cortical system of lymphoid tissue structure and function is an important concept. We cannot at the present time regard that the concept is established fact. Final judgment must await additional work and the clarification of some of the inconsistencies which appear to exist. It seems reasonable that lymphoid tissue is one of the end organs of adrenal cortical hormone and that it may perhaps play a role in the response of the organism to stress. It seems quite clear that the sugar hormone of the adrenal cortex is capable of producing structural alterations in lymphoid tissue. Change in thoracic duct lymphocyte numbers as a result of augmentation in the amount of available adrenal cortical hormone is at present controversial. Experiments in this laboratory have failed to demonstrate it. The production of lymphopenia, at least in some species and possibly in man, by increasing available sugar hormone is supported by some evidence. The exact mechanism of production of lymphopenia is open to question, its relationship to changes in lymphoid tissue structure being one of inference. The converse situation—absolute lympocytosis resulting from deprivation of adrenal cortical hormone—is the subject of controversial reports. At best, it must be admitted that relatively slight alterations from the accepted normal range of lymphocyte values occur in the adrenal insufficient organism. Changes in plasma gamma globulins and antibody titers associated with changes in the amount of available cortical hormone are reported. It should be clarified whether such changes have necessarily resulted from lymphocyte dissolution or are related to other of the variegated actions of adrenal cortical hormone. The relationship of adrenal cortical hormone to lymphoid tissue and lymphocytes and the relationship of the latter to the response of the organism to stress must indeed be complex. It is reasonably well established that the life span of the lymphocyte is very short indeed1,58,22 and each lymphocyte presumably liberates its metabolically important contents within a few hours at the most. If stress continues for any period of time, as often it does, it is difficult to visualize the wisdom of interfering with the production of metabolically vital substances in order to secure the transient benefits of lymphoid tissue dissolution. It is also somewhat difficult to regard as proved that the various changes reported after hormone augmentation or deprivation necessarily represent the normal mechanism by which these factors are regulated and kept within physiologic limits. More investigations are required to answer such questions and to further elucidate the interrelationship of the adrenal cortex and lymphoid tissues.


Author(s):  
Pushpendra Narvariya ◽  
Prof. Joseph Singh

The current study aims to analyze the relationship of selected kinematic variables to the technique of pull shot in cricket. For the purpose of the study the researcher purposively selected five male inter-university cricket players from lnipe, gwalior of 18 to 24 years., the technique of pull shot in batting performance of each selected subjects was recorded on the basis of certain criteria (point system). It was divided into 2 components; 1. placement of feet and 2. execution (contact) each consist of maximum 10 points. The angles at selected joints were recorded to the nearest degree. The c.g. was measured nearest to the 1/10th of the centimetre. On the basis of sequence photographs obtained from the videography, the scholar developed stick figures from which selected kinematic variables was calculated. The center of gravity of whole body was determined by kinovea software. To find the the relationship of selected kinematic variables to the technique of pull shot in cricket pearson product moment correlation coefficient was used by means of spss software. It was found that, in case of moment execution angle at left shoulder joint and angle at left elbow joint showed significant relationship with performance.


1927 ◽  
Vol 23 (1) ◽  
pp. 29-32
Author(s):  
M. N. Cheboksarov ◽  
Z. I. Malkin

The question of the relationship of the endocrine glands, and in particular the adrenal glands, to immunity has not yet been finally resolved: while some authors recognize only the indirect importance of the endocrine organs in the fight against infection, given the extremely extensive biological role of these organs in the life of the animal body, others are inclined to seek a more direct relationship, allowing their participation or in the production of antithelials, or in the neutralization of bacterial toxins.


2016 ◽  
Vol 19 (3) ◽  
pp. 12-22
Author(s):  
P E Sadchikov ◽  
I L Goldman ◽  
S V Razin ◽  
A D Chernousov ◽  
L I Alekseeva ◽  
...  

In present critical review of systematized materials on the breakthrough achievements of the last decade - the discovery of the effect of protein lactoferrin (LF) on bone formation. It is shownthat LF increases the number of osteoblasts, stimulate their proliferation and differentiation, and prevents their destruction. Action of LF exceeds that of many other previously established bone-forming factors. LF increases the ability of osteoblasts to synthesize and mineralize bone matrix. Apparently, the effect of LF on bone anabolism ensured by the presence of specific receptors on osteoblasts. It was found that LF also inhibits the formation of osteoclasts. Experimental studies have demonstrated that LF prevents the destruction of bone tissue in ovariectomizedanimals and, thus, developing the type of postmenstrual osteoporosis in women. We get the first clinical studies demonstrating an increase in the period of healing of bone injuries while reducing the level of endogenous LF. Since molecular research establishes that the expression of the LF gene is regulated by estrogen, which reduces the development of postmenopausal osteoporosis (PMO) in women, there is a need to further investigate the relationship of these processes, which will help to create a basis for the management of bone formation.


Author(s):  
Minoru Innami ◽  
Masayo Okumura ◽  
Junichi Otogoto ◽  
Eiji Kondo ◽  
Norio Sogawa ◽  
...  

Introduction: The oral function with many teeth affects the health maintenance of the whole body and brain activation of the older people. This study investigates the relationship between cognitive and oral functions, and the effect of tongue and lip motor training on cognitive function. Methods: One hundred subjects (age > 65) were investigated Mini-Mental State Examination (MMSE), their number of present teeth, masticatory function, occlusal force, and oral diadochokinesis (ODK), and correlations between their MMSE scores and the other factors were discussed. Fifteen subjects (5 non-impairment group: NIG, 10 impairment group: IG) participated in tongue and lip motor training three times daily for 15 months. Their MMSE scores, masticatory function, occlusal force, and ODK times were measured every three months. Results: Their MMSE scores correlated with age, number of present teeth, masticatory function, and ODK. Furthermore, multiple regression analysis showed that MMSE scores were strongly related to age and ODK. MMSE scores of IG were significantly higher after 15 months of pronunciation than before training and three months after training started. In both groups, ODK times after 15 months of training were significantly higher than before the training and three months training started. Their masticatory function and occlusal force in the IG showed no significant differences during the 15 months of training. Conclusions: The findings suggest that cognitive function may be related to oral function, especially pronunciation, and those 15 months of tongue and lip motor training is effective in improving cognitive and pronunciation functions.


2015 ◽  
Vol 32 (2) ◽  
pp. 125-136 ◽  
Author(s):  
Alba Gómez-Cabello ◽  
Germán Vicente-Rodríguez ◽  
Isabel Navarro-Vera ◽  
Diana Martinez-Redondo ◽  
Carmen Díez-Sánchez ◽  
...  

The aim of this study was to provide information about the relationship of bone mineral content (BMC) and density (BMD) with some physical-fitness-related variables in a sample of women with fibromyalgia (FM) and age-matched women without FM. Twenty-eight women clinically diagnosed with FM (age 51.1 ± 8.4 yr, M ± SD) and 22 age-matched controls participated in the study. Whole-body BMC and BMD, lean mass, handgrip strength, quadriceps strength, and cardiovascular fitness were measured in all participants. The association between physical-fitness variables and bone-related variables was tested by linear regression controlling for body weight as a possible confounder. There were no differences in BMC or BMD between groups. Women with FM had lower values of handgrip strength, quadriceps strength, and VO2peak than the control group. Handgrip strength and aerobic capacity were associated with BMC and BMD and quadriceps strength was associated with BMD in women with FM; however, only VO2peak was associated with BMC in the group of women without FM. Bone mass of women with FM may be more susceptible to changes in physical fitness than that of the women without fibromyalgia.


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