scholarly journals Correlation of prostatic morphological parameters and clinical progression in aging Chinese men with benign prostatic hyperplasia: results from a cross-sectional study

2019 ◽  
Author(s):  
Subo Qian ◽  
Haibo Shen ◽  
Shun Zhang ◽  
Jun Gu ◽  
Jun Qi ◽  
...  

Abstract Objectives Our study aimed to investigate the correlation of prostatic morphological parameters and benign prostatic hyperplasia (BPH) clinical progression in aging Chinese men. Methods In this retrospective study, a total of 1038 patients were reviewed. Prostatic morphology was measured by transrectal ultrasound (TRUS). Detailed medical history of all candidates were recorded and analysed after being classified by specific prostatic measurements. Univariate and multivariate logistic regression analyses were used to estimate the correlation between variables. Results The cumulative incidence of BPH clinical progression was 63.68% (661/1038) in study population. Prostate volume (PV), transitional zone volume (TZV), transitional zone index (TZI) and intravesical prostatic protrusion (IPP) were all positively associated with BPH progression (all p < 0.001). Patients with a PV > 60 mL, TZV > 15 mL, TZI > 0.5 or IPP > 5 mm had a significantly higher possibility of overall BPH clinical progression (adjusted odds ratio (OR): 2.485, 1.678, 1.886 and 1.924, respectively; 95% confidence interval (CI): 1.559-3.960, 1.131-2.489, 1.379-2.579 and 1.357-2.728, correspondingly). Conclusion Prostatic morphological parameters are significantly associated with BPH clinical progression. Patients with larger prostatic morphological parameters are more easily to progress. As a result, reasonable management should be timely considered for those patients before clinical progression occurs.

2020 ◽  
Vol 38 (11) ◽  
pp. 2923-2931
Author(s):  
Y. Wu ◽  
Y. Ding ◽  
Q. F. Cao ◽  
S. B. Qian ◽  
C. Wang ◽  
...  

Abstract Purpose Increasing evidence shows that many metabolic factors are involved in the progression of benign prostatic hyperplasia (BPH). We aimed to assess the relationship between the status of glucose homeostasis and prostate size in aging Chinese males undergoing transurethral resection of the prostate (TURP) for BPH. Methods A total of 1006 medical records of BPH patients undergoing TURP were reviewed. Prostate size was measured by transrectal ultrasound. Annual total prostate (TP) and transitional zone (TZ) growth rates were calculated. According to the American Diabetes Association criteria, the patients were categorized as normoglycemic, prediabetic, or diabetic. Levels of glucose homeostasis and other variables were considered independent variables in an effort to evaluate any potential correlations using non-adjusted and multivariate-adjusted regression models. Results A total of 659 individuals were included in the study. BPH patients < 70 years old and ≥ 70 years old in the normoglycemic group had a stable prostate growth rate. The change in prostate size in those younger than 70 years, however, was faster in the prediabetic and diabetic group. Further analysis revealed that abnormal glucose homeostasis was positively correlated with prostate size. In those younger than 70 years, compared with the normal glucose group, the adjusted odds ratio (OR) for TP and TZ enlargement in the prediabetic group was 2.27 (95%CI 1.29–4.00) and 3.19 (95%CI 1.78–5.72), respectively, and the adjusted ORs were 4.74 (95%CI 2.18–10.30) and 6.16 (95%CI 2.70–14.06), respectively, for men with diabetes. However there was no significant difference among men aged ≥ 70 years. Conclusions Among patients undergoing TURP, the prostate volume and growth rate were affected by different status of glucose homeostasis. Hyperglycemia may play an important role in prostate growth.


2018 ◽  
Vol 09 (01) ◽  
pp. 30-33
Author(s):  
Iffat Raza ◽  
Mahrukh Kamran ◽  
Sadaf Shaheen

Objective: Analyze grading of IPSS (International Prostatic Symptom Score) and PV (Prostate Volume) of BPH patients in a subset of Karachi Population. Methodology: A 103 Benign prostatic hyperplasia(BPH) patients were recruited. A cross-sectional study was done Prostate Volume was recorded along with their IPSS also noted. Result: Among BPH patients 25.2% patients had prostate volume of 25 to 30 ml , 52.5% of patient had prostate volume of 30 to 50ml and 22.3% of patients had prostate volume above 50 ml. In IPSS grading 82.5% patients were under moderate symptom group and 17.5% were under severe symptom group. Conclusion: International Prostatic Symptom Score continues to increase as Prostate volume increases


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1784-1787
Author(s):  
Archana S ◽  
Kumaresan M ◽  
Sangeetha A ◽  
Balaji Karunakaran ◽  
Yuvaraj Maria Francis

Benign prostatic hyperplasia (BPH) is one of the most common diseases encountered in urology practice which commonly occurs in the ageing man. Similarly, diabetes, hypertension, cardiovascular disease and erectile dysfunction also increases with ageing. This study is an attempt to look at the percentage of patients presenting with any associated illness and then to assess the risk of smoking and alcohol consumption and their socioeconomic status of our group of patients by taking a thorough history of BPH patients. The study was conducted in the urology department saveetha medical college and hospital. This was a prospective cross-sectional study from October 2019 till February 2020. In this study, 150 BPH patients history was taken, and data regarding their co-morbid conditions, smoking habits and alcohol consumption were taken, and results were analyzed. Among the co-morbid conditions in this group of patients, the most typical medical condition found was diabetes (46%) and the second most common cause was erectile dysfunction (32%). Further, public health perspective research with factual data collected through various hospitals to assess future trends in BPH incidence rates and co-morbid conditions must be strongly encouraged to identify risk factors for the Indian population.


2020 ◽  
Vol 27 (12) ◽  
pp. 2553-2557
Author(s):  
Moin Anwar ◽  
Muhammad Saifullah ◽  
Muhammad Tahir Bashir Malik ◽  
Muhammad Irfan Munir ◽  
Muhammad Akmal ◽  
...  

Objectives: Our objective was determination of the correlation between mean bladder wall thickness and mean IPSS in BPH diagnosed patients. Study Design: Cross sectional study. Setting: Department of Urology & Renal Transplantation, Punjab Medical College / Allied Hospital, Faisalabad. Period: Six months from 01-04-2016 to 30-09-2016. Material & Methods: Total 70 patients were enrolled for study from outpatient department of Urology, AHF. IPSS was calculated and recorded. Transabdominal ultrasound KUB was done to measure bladder wall thickness. Urine complete examination and culture was done to rule out UTI. Existence of bladder tumor was ruled out by previous history and ultrasonography. The data was collected on a Proforma by myself. Results: Out of 70 enrolled cases, 47.14% (n=33) were aged 50-60 years whereas 52.86% (n=37) were 61-70 years of age. Mean age was calculated as 61.27+5.31 years. Mean Bladder Wall thickness was 3.64+0.72 and IPSS was calculated to be 12.84+2.79 (r0.9056). Correlation between mean bladder wall thickness and mean IPSS in patients having benign prostatic hyperplasia was calculated as significant. Conclusion: In patients suffering from BOO due to BPH, we have found a very strong positive correlation between mean IPSS and mean BWT. However, bigger studies using standardized techniques are required to establish this fact.


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