scholarly journals Effect of biological larviciding with Bacillus thuringiensis israelensis for malaria control on non-target vector mosquito species in rural Burkina Faso – A cluster randomized trial

2019 ◽  
Author(s):  
Peter Dambach ◽  
Till Bärnighausen ◽  
Anges Yadouleton ◽  
Martin Dambach ◽  
Issouf Traore ◽  
...  
Keyword(s):  
Bacillus Thuringiensis ◽  
Burkina Faso ◽  
Malaria Control ◽  
Negative Binomial ◽  
Urban Setting ◽  
Bacillus Thuringiensis Israelensis ◽  
Breeding Sites ◽  
Rural Villages ◽  
Additional Tool ◽  
The Impact

Abstract Background: Biological larviciding is an additional tool that can help address the current dilemma in malaria control, namely vector resistances to pyrethroids and shifting of biting activity to times when people are not protected. Although malaria interventions primarily target Anopheles mosquitoes, there might be an impact on populations of other mosquito genera that share the same breeding sites. In this study we research to what extent Culex and Aedes mosquitoes, the primary vectors of numerous zoonotic diseases, are affected by larviciding interventions against malaria mosquitoes. Methods: We researched the impact of different larviciding choices with Bacillus thuringiensis israelensis on non-target mosquitoes in 127 rural villages and a semi-urban town in a health district in Northwestern Burkina Faso. All villages were distributed into a total of three study arms with different larviciding choices: full, selective and untreated control. Geographically close villages were distributed into clusters to avoid contamination between treated and untreated villages. Adult mosquitoes were captured in light traps inside and outside houses during the rainy seasons of a baseline and an intervention year. A negative binomial regression was used to determine the reductions achieved through larviciding among different mosquito genera.Results: Larviciding interventions against malaria showed only limited or no impact against Culex mosquitoes, while against Aedes, reductions of up to 34% were achieved when all detected breeding sites in the public space were treated. While the semi-urban setting showed high abundance of Culex, in the rural villages we captured more Aedes. Conclusions: Future larviciding programs should be evaluated for including the treatment of Aedes and Culex breeding habitats. Since the major cost components of such programs are labor and transport, other disease vectors could be targeted at little additional cost.

scholarly journals Is biological larviciding against malaria a starting point for integrated multi-disease control? Observations from a cluster randomized trial in rural Burkina Faso

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0253597
Author(s):  
Peter Dambach ◽  
Till Bärnighausen ◽  
Anges Yadouleton ◽  
Martin Dambach ◽  
Issouf Traoré ◽  
...  
Keyword(s):  
Negative Binomial ◽  
Mosquito Species ◽  
Negative Binomial Regression ◽  
Cluster Randomized Trial ◽  
Disease Vectors ◽  
Bacillus Thuringiensis Israelensis ◽  
Breeding Sites ◽  
Rural Villages ◽  
Starting Point ◽  
The Impact

Objectives To evaluate the impact of anti-malaria biological larviciding with Bacillus thuringiensis israelensis on non-primary target mosquito species in a rural African setting. Methods A total of 127 villages were distributed in three study arms, each with different larviciding options in public spaces: i) no treatment, ii) full or iii) guided intervention. Geographically close villages were grouped in clusters to avoid contamination between treated and untreated villages. Adult mosquitoes were captured in light traps inside and outside houses during the rainy seasons of a baseline and an intervention year. After enumeration, a negative binomial regression was used to determine the reductions achieved in the different mosquito species through larviciding. Results Malaria larviciding interventions showed only limited or no impact against Culex mosquitoes; by contrast, reductions of up to 34% were achieved against Aedes when all detected breeding sites were treated. Culex mosquitoes were captured in high abundance in semi-urban settings while more Aedes were found in rural villages. Conclusions Future malaria larviciding programs should consider expanding onto the breeding habitats of other disease vectors, such as Aedes and Culex and evaluate their potential impact. Since the major cost components of such interventions are labor and transport, other disease vectors could be targeted at little additional cost.

scholarly journals Effects of terrorist attacks on access to maternal healthcare services: a national longitudinal study in Burkina Faso

2020 ◽  
Vol 5 (9) ◽  
pp. e002879
Author(s):  
Thomas Druetz ◽  
Lalique Browne ◽  
Frank Bicaba ◽  
Matthew Ian Mitchell ◽  
Abel Bicaba
Keyword(s):  
Antenatal Care ◽  
Burkina Faso ◽  
Negative Binomial ◽  
Terrorist Attack ◽  
Healthcare Services ◽  
Terrorist Attacks ◽  
Cesarean Sections ◽  
Maternal Healthcare ◽  
District Hospitals ◽  
The Impact

IntroductionMost of the literature on terrorist attacks’ health impacts has focused on direct victims rather than on distal consequences in the overall population. There is limited knowledge on how terrorist attacks can be detrimental to access to healthcare services. The objective of this study is to assess the impact of terrorist attacks on the utilisation of maternal healthcare services by examining the case of Burkina Faso.MethodsThis longitudinal quasi-experimental study uses multiple interrupted time series analysis. Utilisation of healthcare services data was extracted from the National Health Information System in Burkina Faso. Data span the period of January 2013–December 2018 and include all public primary healthcare centres and district hospitals. Terrorist attack data were extracted from the Armed Conflict Location and Event Data project. Negative binomial regression models were fitted with fixed effects to isolate the immediate and long-term effects of terrorist attacks on three outcomes (antenatal care visits, of facility deliveries and of cesarean sections).ResultsDuring the next month of an attack, the incidence of assisted deliveries in healthcare facilities is significantly reduced by 3.8% (95% CI 1.3 to 6.3). Multiple attacks have immediate effects more pronounced than single attacks. Longitudinal analysis show that the incremental number of terrorist attacks is associated with a decrease of the three outcomes. For every additional attack in a commune, the incidence of cesarean sections is reduced by 7.7% (95% CI 4.7 to 10.7) while, for assisted deliveries, it is reduced by 2.5% (95% CI 1.9 to 3.1) and, for antenatal care visits, by 1.8% (95% CI 1.2 to 2.5).ConclusionTerrorist attacks constitute a new barrier to access of maternal healthcare in Burkina Faso. The exponential increase in terrorist activities in West Africa is expected to have negative effects on maternal health in the entire region.

scholarly journals Risk of Plasmodium falciparum infection in south-west Burkina Faso - potential impact of expanding eligibility for seasonal malaria chemoprevention

2021 ◽  
Author(s):  
Anne L Wilson ◽  
Steve W Lindsay ◽  
Alfred Tiono ◽  
Jean Baptiste Yaro ◽  
Hilary Ranson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Malaria Transmission ◽  
Malaria Control ◽  
Control Measures ◽  
Sub Saharan Africa ◽  
South West ◽  
Seasonal Malaria Chemoprevention ◽  
The Impact

Abstract Background Burkina Faso has one of the highest malaria burdens in sub-Saharan Africa despite the mass deployment of insecticide-treated nets (ITNs) and use of seasonal malaria chemoprevention (SMC) in children aged up to 5 years. Identification of risk factors for Plasmodium falciparum infection in rural Burkina Faso could help to identify and target malaria control measures. Methods A cross-sectional survey of 1,199 children and adults was conducted during the peak malaria transmission season in south-west Burkina Faso in 2017. Logistic regression was used to identify risk factors for microscopically confirmed P. falciparum infection. A malaria transmission dynamic model was used to determine the impact on malaria cases averted of administering SMC to children aged 5–15 year old. Results P. falciparum prevalence was 32.8% in the study population. Children aged 5 to < 10 years old were at 3.74 times the odds (95% CI = 2.68–5.22, p < 0.001) and children aged 10 to 15 years old at 3.14 times the odds (95% CI = 1.20–8.21, p = 0.02) of P. falciparum infection compared to children aged less than 5 years old. Administration of SMC to children aged up to 10 years is predicted to avert an additional 57 malaria cases per 1000 population per year (9.4% reduction) and administration to children aged up to 15 years would avert an additional 89 malaria cases per 1000 population per year (14.6% reduction) in the Cascades Region, assuming coverage of pyrethroid-piperonyl butoxide ITNs. Conclusion Malaria infections were high in all age strata, although highest in children aged 5 to 15 years, despite roll out of core malaria control interventions. Given the burden of infection in school-age children, extension of the eligibility criteria for SMC could help reduce the burden of malaria in Burkina Faso and other countries in the region.

scholarly journals Routine implementation costs of larviciding with Bacillus thuringiensis israelensis against malaria vectors in a district in rural Burkina Faso

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Peter Dambach ◽  
Michael Schleicher ◽  
Hans-Christian Stahl ◽  
Issouf Traoré ◽  
Norbert Becker ◽  
...  
Keyword(s):  
Bacillus Thuringiensis ◽  
Burkina Faso ◽  
Malaria Vectors ◽  
Bacillus Thuringiensis Israelensis ◽  
Implementation Costs

scholarly journals Parasitological Indices of Malaria Transmission in Children under Fifteen Years in Two Ecoepidemiological Zones in Southwestern Burkina Faso

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Aristide S. Hien ◽  
Ibrahim Sangaré ◽  
Sanata Coulibaly ◽  
Moussa Namountougou ◽  
Léa Paré-Toé ◽  
...  
Keyword(s):  
Burkina Faso ◽  
Malaria Transmission ◽  
Malaria Control ◽  
Future Research ◽  
Rice Area ◽  
Significant Difference ◽  
Bobo Dioulasso ◽  
Effective Decision Making ◽  
Epidemiological Profile ◽  
The Impact

Twenty years after the latest publications performed on the parasitological indices of malaria transmission in northwest of the second city of Burkina Faso, it was important to update the epidemiological profile of malaria in children under the age of 15 years. The objective of this study was to determine and compare the parasitological parameters of malaria transmission by season, area, and age in the two zones (rice and savanna) in the northwest of Bobo-Dioulasso, Burkina Faso. Overall, the results showed that there was no significant difference in the parasitological indices of malaria transmission within children under fifteen years between the rice site and the savannah site and whatever the season (P>0.05). The profound environmental modifications that occurred in the rice zone would have led to changes in vector behavior and consequently to changes in the epidemiological profile of malaria, contrary to the results obtained since the last publications. An entomological study correlated with this study is therefore necessary for effective decision-making for the malaria control in both areas. Future research must now focus on the impact that these profound environmental modifications of rice area are having on malaria control in Burkina Faso.

The potential for malaria control with the biological larvicide Bacillus thuringiensis israelensis (Bti) in Peru and Ecuador

Acta Tropica ◽  
1995 ◽  
Vol 60 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Axel Kroeger ◽  
Olaf Horstick ◽  
Christine Riedl ◽  
Achim Kaiser ◽  
Norbert Becker
Keyword(s):  
Bacillus Thuringiensis ◽  
Malaria Control ◽  
Bacillus Thuringiensis Israelensis

ANALISIS RISIKO OPERASIONAL MENGGUNAKAN PENDEKATAN DISTRIBUSI KERUGIAN DENGAN METODE AGREGAT

2011 ◽  
Vol 10 (2) ◽  
pp. 1
Author(s):  
Y. ARBI ◽  
R. BUDIARTI ◽  
I G. P. PURNABA
Keyword(s):  
Negative Binomial Distribution ◽  
Binomial Distribution ◽  
Negative Binomial ◽  
Financial Institution ◽  
Expected Value ◽  
Insurance Companies ◽  
Limited Data ◽  
Loss Distribution Approach ◽  
Potential Loss ◽  
The Impact

Operational risk is defined as the risk of loss resulting from inadequate or failed internal processes or external problems. Insurance companies as financial institution that also faced at risk. Recording of operating losses in insurance companies, were not properly conducted so that the impact on the limited data for operational losses. In this work, the data of operational loss observed from the payment of the claim. In general, the number of insurance claims can be modelled using the Poisson distribution, where the expected value of the claims is similar with variance, while the negative binomial distribution, the expected value was bound to be less than the variance.Analysis tools are used in the measurement of the potential loss is the loss distribution approach with the aggregate method. In the aggregate method, loss data grouped in a frequency distribution and severity distribution. After doing 10.000 times simulation are resulted total loss of claim value, which is total from individual claim every simulation. Then from the result was set the value of potential loss (OpVar) at a certain level confidence.

scholarly journals Predicting distribution of malaria vector larval habitats in Ethiopia by integrating distributed hydrologic modeling with remotely sensed data

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ai-Ling Jiang ◽  
Ming-Chieh Lee ◽  
Guofa Zhou ◽  
Daibin Zhong ◽  
Dawit Hawaria ◽  
...  
Keyword(s):  
Malaria Vector ◽  
Malaria Control ◽  
Remotely Sensed ◽  
Larval Habitat ◽  
Validation Dataset ◽  
Significant Shift ◽  
Remotely Sensed Data ◽  
Larval Habitats ◽  
Common Land Model ◽  
The Impact

AbstractLarval source management has gained renewed interest as a malaria control strategy in Africa but the widespread and transient nature of larval breeding sites poses a challenge to its implementation. To address this problem, we propose combining an integrated high resolution (50 m) distributed hydrological model and remotely sensed data to simulate potential malaria vector aquatic habitats. The novelty of our approach lies in its consideration of irrigation practices and its ability to resolve complex ponding processes that contribute to potential larval habitats. The simulation was performed for the year of 2018 using ParFlow-Common Land Model (CLM) in a sugarcane plantation in the Oromia region, Ethiopia to examine the effects of rainfall and irrigation. The model was calibrated using field observations of larval habitats to successfully predict ponding at all surveyed locations from the validation dataset. Results show that without irrigation, at least half of the area inside the farms had a 40% probability of potential larval habitat occurrence. With irrigation, the probability increased to 56%. Irrigation dampened the seasonality of the potential larval habitats such that the peak larval habitat occurrence window during the rainy season was extended into the dry season. Furthermore, the stability of the habitats was prolonged, with a significant shift from semi-permanent to permanent habitats. Our study provides a hydrological perspective on the impact of environmental modification on malaria vector ecology, which can potentially inform malaria control strategies through better water management.

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