scholarly journals Objective Optical Quality in Eyes with Customized Selection of Aspheric Intraocular Lens Implantation

2019 ◽  
Author(s):  
Qing-Qing Tan ◽  
Jia Lin ◽  
Jing Tian ◽  
Xuan Liao ◽  
Chang-Jun Lan
Keyword(s):  
Visual Acuity ◽  
Spherical Aberration ◽  
Optical Quality ◽  
Control Group ◽  
Modulation Transfer ◽  
Iol Implantation ◽  
Postoperative Visual Acuity ◽  
Aspheric Iol ◽  
Significant Difference ◽  
Selection Of

Abstract Backgroud To compare the postoperative optical quality in eyes with customized selection and random selection of aspheric intraocular lens (IOL) implantation. Methods A prospective, nonrandomized study was implemented in adult cataract patients who underwent unilateral phacoemulsification with aspheric IOL implantation. Patients were allocated into two treatment groups: a customized group and a control group. In the customized group, the aspheric IOL selection was based on the corneal spherical aberration to enable the postoperative target ocular spherical aberration closest to zero; in the control group, the aspheric IOLs were chosen using a random strategy. Primary outcome measurements included the following objective optical quality assessments: higher-order aberrations obtained by a Hartmann-shack aberrometer at 4mm and 6mm pupil diameters; objective scatter index (OSI), modulation transfer function (MTF) cut-off, Strehl ratio (SR) and a simulated contrast visual acuity—optical quality analysis system value (OV) obtained by a double-pass system with a 4-mm aperture. Subjective visual acuity was measured as secondary outcome. All the patients were followed up for 3 months. Results Eighty-four patients in the customized group and 78 patients in the control group were evaluated. There was no significant difference in postoperative visual acuity between the two groups (P>0.05). Significantly less ocular higher-order aberrations were shown in the customized group (P<0.05). No significant difference was shown in OSI, MTF cut-off, SR and OV between the two groups (P>0.05). Conclusions Although customized selection of aspheric IOL implantation showed less postoperative ocular aberrations, it performed similarly to random selection of aspheric IOL implantation in terms of postoperative visual acuity, simulated contrast visual acuity, intraocular scatter, modulation transfer function and Strehl ratio.

scholarly journals Objective Optical Quality in Eyes with Customized Selection of Aspheric Intraocular Lens Implantation

2019 ◽  
Author(s):  
Qing-Qing Tan ◽  
Jia Lin ◽  
Jing Tian ◽  
Xuan Liao ◽  
Chang-Jun Lan
Keyword(s):  
Visual Acuity ◽  
Spherical Aberration ◽  
Optical Quality ◽  
Control Group ◽  
Modulation Transfer ◽  
Iol Implantation ◽  
Postoperative Visual Acuity ◽  
Aspheric Iol ◽  
Significant Difference ◽  
Selection Of

Abstract Backgroud To compare the postoperative optical quality in eyes with customized selection and random selection of aspheric intraocular lens (IOL) implantation. Methods A prospective, nonrandomized study was implemented in adult cataract patients who underwent unilateral phacoemulsification with aspheric IOL implantation. Patients were allocated into two treatment groups: a customized group and a control group. In the customized group, the aspheric IOL selection was based on the corneal spherical aberration to enable the postoperative target ocular spherical aberration closest to zero; in the control group, the aspheric IOLs were chosen using a random strategy. Primary outcome measurements included the following objective optical quality assessments: higher-order aberrations obtained by a Hartmann-shack aberrometer at 4mm and 6mm pupil diameters; objective scatter index (OSI), modulation transfer function (MTF) cut-off, Strehl ratio (SR) and a simulated contrast visual acuity—optical quality analysis system value (OV) obtained by a double-pass system with a 4-mm aperture. Subjective visual acuity was measured as secondary outcome. All the patients were followed up for 3 months. Results Eighty-four patients in the customized group and 78 patients in the control group were evaluated. There was no significant difference in postoperative visual acuity between the two groups (P>0.05). Significantly less ocular higher-order aberrations were shown in the customized group (P<0.05). No significant difference was shown in OSI, MTF cut-off, SR and OV between the two groups (P>0.05). Conclusions Although customized selection of aspheric IOL implantation showed less postoperative ocular aberrations, it performed similarly to random selection of aspheric IOL implantation in terms of postoperative visual acuity, simulated contrast visual acuity, intraocular scatter, modulation transfer function and Strehl ratio.

scholarly journals Objective Optical Quality in Eyes with Customized Selection of Aspheric Intraocular Lens Implantation

2019 ◽  
Author(s):  
Qing-Qing Tan ◽  
Jia Lin ◽  
Jing Tian ◽  
Xuan Liao ◽  
Chang-Jun Lan
Keyword(s):  
Visual Acuity ◽  
Spherical Aberration ◽  
Optical Quality ◽  
Control Group ◽  
Modulation Transfer ◽  
Iol Implantation ◽  
Postoperative Visual Acuity ◽  
Aspheric Iol ◽  
Significant Difference ◽  
Selection Of

Abstract Backgroud To improve the aspheric intraocular lens (IOL) selection strategy in cataract surgery. Methods A prospective, nonrandomized study was implemented in adult cataract patients who underwent unilateral phacoemulsification with aspheric IOL implantation. Patients were allocated into two treatment groups: a customized group and a control group. In the customized group, the aspheric IOL selection was based on the corneal spherical aberration to enable the postoperative target ocular spherical aberration closest to zero; in the control group, the aspheric IOLs were chosen using a random strategy. Primary outcome measurements included the following objective optical quality assessments: higher-order aberrations obtained by a Hartmann-shack aberrometer at 4mm and 6mm pupil diameters; objective scatter index (OSI), modulation transfer function (MTF) cut-off, Strehl ratio (SR) and a simulated contrast visual acuity—optical quality analysis system value (OV) obtained by a double-pass system with a 4-mm aperture. Subjective visual acuity was measured as secondary outcome. All the patients were followed up for 3 months. Results Eighty-four patients in the customized group and 78 patients in the control group were evaluated. There was no significant difference in postoperative visual acuity between the two groups (P>0.05). Significantly less ocular higher-order aberrations were shown in the customized group (P<0.05). No significant difference was shown in OSI, MTF cut-off, SR and OV between the two groups (P>0.05). Conclusions Although customized selection of aspheric IOL implantation showed less postoperative ocular aberrations, it performed similarly to random selection of aspheric IOL implantation in terms of postoperative visual acuity, simulated contrast visual acuity, intraocular scatter, modulation transfer function and Strehl ratio.

scholarly journals Comparison of the visual performance of iris-fixated phakic lens and implantable collamer lens to correct high myopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiao-ling Jiao ◽  
Jun Li ◽  
Zhe Yu ◽  
Ping-hui Wei ◽  
Hui Song
Keyword(s):  
Visual Acuity ◽  
High Myopia ◽  
Optical Quality ◽  
Visual Performance ◽  
Quality Analysis ◽  
Modulation Transfer ◽  
Implantable Collamer Lens ◽  
Good Visual Acuity ◽  
Significant Difference ◽  
Group 6

Abstract Background To compare visual performance between the iris-fixated phakic intraocular len (pIOL) and implantable collamer len (ICL) to correct high myopia. Methods Twenty-four eyes underwent iris-fixated pIOL implantation and 24 eyes underwent ICL implantation. At the 6-month follow-up, the best-corrected visual acuity (BCVA) and uncorrected distance visual acuity (UDVA) were compared between the iris-fixated pIOL and ICL groups. The objective scatter index (OSI), modulation transfer function (MTF) cutoff, and ocular aberrations were performed to evaluate postoperative visual quality between the two groups. Results No significant difference was found in UDVA, BCVA, and spherical equivalent between the iris-fixated pIOL and ICL groups (P > 0.05). Six months after surgery, the following values were significantly higher in the ICL group than in the iris-fixated pIOL group: MTF cutoff, strehl ratio and optical quality analysis system values at contrasts of 9 %, 20 %, and 100 % (P < 0.01). The OSI in the iris-fixated pIOL group was higher than in the ICL group 6 months after surgery (P < 0.01). All high-order aberrations were slightly more severe in the iris-fixated pIOL group than in the ICL group 6 months after surgery, although only trefoil (P = 0.023) differed significantly in this regard. Conclusions Both iris-fixated lenses and ICLs can provide good visual acuity. ICLs confer better visual performance in MTF-associated parameters and induce less intraocular light scattering than iris-fixated pIOLs.

scholarly journals Comparative Analysis of Visual Performance and Optical Quality with a Rotationally Asymmetric Multifocal Intraocular Lens and an Apodized Diffractive Multifocal Intraocular Lens

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Xiao Wang ◽  
Haixia Tu ◽  
Yong Wang
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Intraocular Lens ◽  
Visual Function ◽  
Optical Quality ◽  
Modulation Transfer ◽  
Multifocal Intraocular Lens ◽  
Distance Visual Acuity ◽  
Age Related ◽  
Significant Difference

Purpose. To compare the short-term visual outcomes and intraocular optical performance of a rotationally asymmetric multifocal intraocular lens (MIOL) (SBL-3, Lenstec, Inc., Christ Church, Barbados) and an apodized diffractive MIOL (the Acrysof IQ ResTOR SN6AD1, Alcon Laboratories, Inc., Fort Worth, Texas, United States). Methods. A prospective, comparative, nonrandomized, and single-center study. Sixty-eight age-related cataract patients (81 eyes) after phacoemulsification cataract surgery and in-the-bag MIOL implantation were enrolled. Thirty-eight eyes received SBL-3, and 43 eyes received SN6AD1. Ophthalmological evaluation included uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), corrected distance visual acuity (CDVA), modulation transfer function (MTF), Strehl ratio (SR), intraocular aberrations (4 mm optical zone), and defocus curve at 3 months postoperatively. The Chinese version of the visual function index-14 (VF-12-CN) and spectacle independence were assessed in all patients. Results. There was no statistically significant difference between groups in postoperative UDVA (p=0.186). Postoperative UIVA and UNVA were significantly better for the SBL-3 group than for the SN6AD1 group (p<0.01). Statistically significant differences were revealed in defocus levels from –3.50 D to −4.00 D with better visual acuities for the SBL-3 group (p<0.01). For intraocular optical quality outcomes, statistically significant differences between groups were observed in RMS of intraocular total aberrations, coma, and trefoil high-order aberrations, presenting significantly higher values of these parameters in the eyes of the SBL-3 group (p < 0.01). Statistically significant differences were revealed in the MTF values at spatial frequencies of 5 and 10 cycles/degree between groups. There were no significant differences in scores of VF-12-CN, and spectacle independence between the groups (p>0.05). Conclusions. Both MIOLs were able to successfully restore visual function after cataract surgery. SBL-3 provided better UIVA and UNVA with a wider range of intermediate vision.

scholarly journals The Effect of Capsulotomy Shape on Intraocular Light-Scattering after Nd:YAG Laser Capsulotomy

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Jun Li ◽  
Zhe Yu ◽  
Hui Song
Keyword(s):  
Visual Acuity ◽  
Light Scattering ◽  
Yttrium Aluminum Garnet ◽  
Optical Quality ◽  
Quality Analysis ◽  
Strehl Ratio ◽  
Modulation Transfer ◽  
Significant Difference ◽  
Satisfaction With Treatment ◽  
Analysis System

Purpose. To investigate the effects of capsulotomy shape on the visual acuity and visual quality after neodymium: yttrium aluminum garnet laser capsulotomy. Methods. In this study, a total of 42 eyes from 35 patients with posterior capsule opacification were divided into the circular and cruciate groups. The corrected distance visual acuity (CDVA), objective scatter index (OSI), modulation transfer function cutoff (MTF cutoff), Strehl ratio, and Optical Quality Analysis System values at contrasts of 100%, 20%, and 9% (OV-100, OV-20, and OV-9) were measured at precapsulotomy and 1 week and 1 month postcapsulotomy. The pseudophakic dysphotopsia questionnaire (PDQ) was used to evaluate the subjects’ satisfaction with treatment. Results. OSI values were significantly higher in the cruciate group than in the circular group at 1 week and 1 month after capsulotomy (P=0.013 and P<0.001). No significant difference was found in the OSI values between the two groups before capsulotomy (t = 0.52; P=0.61). The decrease in OSI was higher in the circular group than in the cruciate group at 1 week and 1 month after capsulotomy (P=0.036 and P=0.019). No significant differences were found in the Strehl ratio, MTF cutoff, CDVA, OV-100, OV-20, and OV-9 between the two groups at 1 week and 1 month after capsulotomy (P>0.05). The PDQ results showed that patients with circular-shaped capsulotomy complained less with intolerance of bright lights than those with cruciate-shaped capsulotomy. Conclusions. Circular-shaped capsulotomy can induce less intraocular light scattering and increase patient satisfaction.

Changes in Higher Order Aberrations after Wavefront-Guided Prk for Correction of Low to Moderate Myopia and Myopic Astigmatism: Two-Year Follow-Up

2007 ◽  
Vol 17 (4) ◽  
pp. 507-514 ◽  
Author(s):  
D. Wygledowska-Promienska ◽  
I. Zawojska
Keyword(s):  
Visual Acuity ◽  
Excimer Laser ◽  
Spherical Aberration ◽  
Higher Order ◽  
Control Group ◽  
Higher Order Aberrations ◽  
Order Root ◽  
Group 2 ◽  
Myopic Astigmatism ◽  
Group 1

Purpose To assess efficacy, safety, and changes in higher order aberrations after wavefront-guided photorefractive keratectomy (PRK) in comparison with conventional PRK for low to moderate myopia with myopic astigmatism using a WASCA Workstation with the MEL 70 G-Scan excimer laser. Methods A total of 126 myopic or myopic-astigmatic eyes of 112 patients were included in this retrospective study. Patients were divided into two groups: Group 1, the study group; and Group 2, the control group. Group 1 consisted of 78 eyes treated with wavefront-guided PRK. Group 2 consisted of 48 eyes treated with spherocylindrical conventional PRK. Results Two years postoperatively, in Group 1, 5% of eyes achieved an uncorrected visual acuity (UCVA) of 0.05; 69% achieved a UCVA of 0.00; 18% of eyes experienced enhanced visual acuity of −0.18 and 8% of −0.30. In Group 2, 8% of eyes achieved a UCVA of 0.1; 25% achieved a UCVA of 0.05; and 67% achieved a UCVA of 0.00 according to logMAR calculation method. Total higher-order root-mean square increased by a factor 1.18 for Group 1 and 1.6 for Group 2. There was a significant increase of coma by a factor 1.74 in Group 2 and spherical aberration by a factor 2.09 in Group 1 and 3.56 in Group 2. Conclusions The data support the safety and effectiveness of the wavefront-guided PRK using a WASCA Workstation for correction of low to moderate refractive errors. This method reduced the number of higher order aberrations induced by excimer laser surgery and improved uncorrected and spectacle-corrected visual acuity when compared to conventional PRK.

scholarly journals Bevacizumab in neoadjuvant treatment of patients with liver metastases from colorectal carcinoma

2010 ◽  
Vol 18 (3) ◽  
pp. 75-78
Author(s):  
Ivan Nikolic ◽  
Svetlana Pavin ◽  
Biljana Kukic ◽  
Bogdan Bogdanovic ◽  
Miroslav Ilic ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastases ◽  
Neoadjuvant Treatment ◽  
Hepatic Metastases ◽  
Response Rates ◽  
Control Group ◽  
Significant Difference ◽  
Experimental Group ◽  
Selection Of Patients ◽  
Selection Of

Background: Liver metastases are the leading cause of death in patients with colorectal cancer. Despite advances in chemotherapy, surgical resection of hepatic metastases is still considered the only curative options. However, the majority of patients have inoperable disease at presentation. Perioperative chemotherapy is the most successful way for improved selection of patients for resection. The aim of the study was to demonstrate if and to what extent does bevacizumab, introduced in chemotherapy, increase response rates, and development of liver metastases. Methods: Our study included 50 patients who were divided in two groups. The experimental group included patients who were treated with bevacizumab plus chemotherapy, and the control group included patients who were treated with chemotherapy only. Results: The comparison showed that the patients who were treated with bevacizumab became candidates for resection of liver metastases in higher percentage (85%:52%). In addition, distribution of patients regarding the development of metastases resulted in statistically significant difference. Ratio between the patients with good response from the experimental and the control group was 67%:39%. Ratio of patients with stable disease was 26%:48%, and of patients with progressive disease, it was 7%:3%. The estimate of margin after resection was statistically insignificant. Conclusion: Bevacizumab in combination with chemotherapy in therapy of liver metastases from primary colorectal cancer improves and increases response rates and development of liver metastases.

scholarly journals A Randomized Controlled Trial of Conbercept Pretreatment before Vitrectomy in Proliferative Diabetic Retinopathy

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaochun Yang ◽  
Jianbiao Xu ◽  
Ruili Wang ◽  
Yan Mei ◽  
Huo Lei ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Controlled Trial ◽  
Control Group ◽  
Intraoperative Bleeding ◽  
Significant Difference ◽  
Pars Plana ◽  
Effective Adjunct

Purpose.To determine the efficacy and safety of preoperative intravitreal conbercept (IVC) injection before vitrectomy for proliferative diabetic retinopathy (PDR).Methods.107 eyes of 88 patients that underwent pars plana vitrectomy (PPV) for active PDR were enrolled. All patients were assigned randomly to either preoperative IVC group or control group. Follow-up examinations were performed for three months after surgery. The primary bioactivity measures were severity of intraoperative bleeding, incidence of early and late recurrent VH, vitreous clear-up time, and best-corrected visual acuity (BCVA) levels. The secondary safety measures included intraocular pressure, endophthalmitis, rubeosis, tractional retinal detachment, and systemic adverse events.Results.The incidence and severity of intraoperative bleeding were significantly lower in IVC group than in the control group. The average vitreous clear-up time of early recurrent VH was significantly shorter in IVC group compared with that in control group. There was no significant difference in vitreous clear-up time of late recurrent VH between the two groups. Patients that received pretreatment of conbercept had much better BCVA at 3 days, 1 week, and 1 month after surgery than control group. Moreover, both patients with improved BCVA were greater in IVC group than in control group at each follow-up.Conclusions.Conbercept pretreatment could be an effective adjunct to vitrectomy in accelerating postoperative vitreous clear-up and acquiring stable visual acuity restoration for PDR.

scholarly journals Influence of Angle κ and Higher-Order Aberrations on Visual Quality Employing Two Diffractive Trifocal IOLs

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Cecilio Velasco-Barona ◽  
Claudia Corredor-Ortega ◽  
Alejandra Mendez-Leon ◽  
Nadia L. Casillas-Chavarín ◽  
Daniel Valdepeña-López Velarde ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Inverse Correlation ◽  
Higher Order ◽  
Controlled Study ◽  
Strehl Ratio ◽  
Higher Order Aberrations ◽  
Iol Implantation ◽  
Postoperative Visual Acuity ◽  
Uncorrected Distance Visual Acuity ◽  
Near Visual Acuity

Prospective, randomized, comparative, and controlled study to estimate the association between angle κ distance and higher-order aberrations (HOAs) with postoperative visual acuity after presbyopia-correcting IOL implantation. Forty-three eyes from 43 patients were included and randomly assigned in two groups for either AT LISA tri 839MP or Acrysof IQ PanOptix IOL implantation. The OPD-Scan III analyzer was utilized to assess the angle κ distance and higher-order aberration (HOAs). Twenty-three eyes were in the Acrysof IQ PanOptix group and 20 patients in the AT LISA tri 839MP group. The uncorrected distance visual acuity (UDVA) for the PanOptix group was 0.092 ± 0.10, whereas for AT LISA tri was 0.050 ± 0.06 (P=0.229). The uncorrected intermediate visual acuity (UIVA) for the PanOptix group was 0.173 ± 0.18, whereas for AT LISA tri, it was 0.182 ± 0.11 (P=0.669). Uncorrected near visual acuity (UNVA) was 0.068 ± 0.04 and 0.085 ± 0.07, respectively (P=0.221). Also, correlation coefficient between HOAs and the Strehl ratio for each group were −0.768 (P<0.0001) and −0.863 (P=0.0001). Patients implanted with both trifocal IOLs showed excellent postoperative visual performance at all distances at the six-month follow-up visit. No association was found between angle κ distance and postoperative visual acuity regardless of the angle κ magnitude or the two trifocal IOLs inner optical diameter. Also, internal aberrations demonstrated a significant inverse correlation with the Strehl ratio for both trifocal IOLs.

scholarly journals Comparison of the Effectiveness of Cognitive Behavioral Therapy and Neurofeedback: Reducing Insomnia Symptoms

2017 ◽  
Vol 9 (7) ◽  
pp. 35 ◽  
Author(s):  
Nooshin Basiri ◽  
Zahra Khayyer ◽  
Habib Hadianfard ◽  
Amirhossein Ghaderi
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Independent Effect ◽  
Control Group ◽  
Significant Difference ◽  
Post Hoc ◽  
And Control ◽  
Insomnia Symptoms ◽  
Selection Of

INTRODUCTION: The term sleep disorder refers to difficulty in initiating sleep, maintaining it or a relaxing sleep despite having enough time to sleep. Cognitive behavioral therapy is a non-drug multi-dimensional treatment that targets behavioral and cognitive factors of this disorder. Some pieces of research have shown that psychiatric and neurological disorders can be distinguished from distinct EEG patterns and neuro-feedback can be used to make a change in these patterns. This study aimed to compare the cognitive behavioral therapy and neuro-feedback in the treatment of insomnia.METHODS: The sample included people, who had already been diagnosed insomnia by a psychiatrist in Isfahan, Iran. Random sampling was employed to choose the participants. Pittsburg sleep quality index (PSQI) was used for the selection of the participants, too. The sample included 40 patients who were randomly selected and interviewed and then diagnostic tests performed on the PSQI, and then they were divided into 3 groups. Data were analyzed using ANOVA. Following the implementation of the independent effect of the treatment was significant and one-way ANOVA with post hoc test L.S.D were carried out on CBT and controls (p = 0.001), CBT, neuro-feedback therapy (p = 0.003), neuro-feedback treatment and control (p = 0.001).RESULTS: It was shown that there was a significant difference between the groups. Based on the descriptive statistics of the 2 abovementioned treatments, neuro-feedback therapy in first position and cognitive-behavioral therapy were most effective in the second position, and the control group showed the lowest efficiency.CONCLUSIONS: Both treatments were significantly effective, and so we can use both neuro-feedback and CBT for the treatment of insomnia.

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