scholarly journals Safety of Pfizer-BioNTech COVID-19 mRNA Vaccine in the Elderly

2021 ◽  
Author(s):  
Katarzyna Korzeniowska ◽  
Artur Cieślewicz ◽  
Katarzyna Grabańska-Martyńska ◽  
Anna Jabłecka
Keyword(s):  
Statistical Analysis ◽  
Adverse Effects ◽  
Older People ◽  
The Elderly ◽  
Viral Disease ◽  
Potential Effect ◽  
Common Phenomenon ◽  
Post Vaccination ◽  
The Past ◽  
Initial Results

Abstract Background. COVID-19 is an infectious viral disease that has affected more than 234 million people and has caused almost 4.8 million deaths worldwide. A patient's age is the most important factor influencing the risk of severe course of the disease. The elderly usually suffer from many ailments, and therefore, polypharmacy is a common phenomenon among them. Our paper presents the initial results of the analysis of adverse effects in the group of older people in the context of participants' pharmacotherapy. Methods. The information concerning post-vaccination adverse effects, COVID-19 in the past and current pharmacotherapy was collected from 200 people aged 60 years or older. Statistical analysis was performed using StatSoft Statistica 13.1 software. Results. Twenty-three participants reported adverse effects after vaccination. Statistical analysis of groups with and without adverse effects revealed significant differences in age, cardiovascular drugs, neurological and psychiatric drugs, analgesics, gastrointestinal drugs, supplements, and vitamins. Conclusions. Obtained results suggest the need to study the potential effect of ongoing pharmacotherapy on the safety and effectiveness of vaccination.

scholarly journals The Effect of Vaccination with Live Attenuated Neethling Lumpy Skin Disease Vaccine on Milk Production and Mortality—An Analysis of 77 Dairy Farms in Israel

Vaccines ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 324 ◽  
Author(s):  
Michal Morgenstern ◽  
Eyal Klement
Keyword(s):  
Adverse Effects ◽  
Milk Production ◽  
Skin Disease ◽  
Linear Models ◽  
Viral Disease ◽  
Lumpy Skin Disease ◽  
Post Vaccination ◽  
Efficient Measure ◽  
Daily Milk Production ◽  
Cattle Farms

Lumpy skin disease (LSD) is an economically important, arthropod borne viral disease of cattle. Vaccination by the live attenuated homologous Neethling vaccine was shown as the most efficient measure for controlling LSD. However, adverse effects due to vaccination were never quantified in a controlled field study. The aim of this study was to quantify the milk production loss and mortality due to vaccination against LSD. Daily milk production, as well as culling and mortality, were retrieved for 21,844 cows accommodated in 77 dairy cattle farms in Israel. Adjusted milk production was calculated for each day during the 30 days post vaccination. This was compared to the preceding month by fitting mixed effects linear models. Culling and mortality rates were compared between the 60 days periods prior and post vaccination, by survival analysis. The results of the models indicate no significant change in milk production during the 30 days post vaccination period. No difference was observed between the pre- and post-vaccination periods in routine culling, as well as in immediate culling and in-farm mortality. We conclude that adverse effects due to Neethling vaccination are negligible.

scholarly journals A Comprehensive Evaluation of Studies on the Adverse Effects of Medications in Australian Aged care Facilities: A Scoping Review

Pharmacy ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 56
Author(s):  
Haider Qasim ◽  
Maree Simpson ◽  
Yann Guisard ◽  
Barbora de Courten
Keyword(s):  
Adverse Effects ◽  
Older People ◽  
Scoping Review ◽  
Adverse Drug Events ◽  
Assessment Tool ◽  
The Elderly ◽  
Aged Care ◽  
Inclusion Criteria ◽  
Care Facilities ◽  
Aged Care Facilities

Aim: this scoping review was designed to identify studies that assess adverse drug reactions (ADRs) for older people in Australian aged care facilities. This review critically evaluates each published study to identify the risk of, or actual, adverse drug events in older people. Inclusion criteria: this review considered any clinical studies that examined the adverse effects of medications in older people who were living in aged care facilities. This review considered qualitative studies, analytical studies, randomized controlled trials (RCTs), descriptive cross-sectional studies, and analytic observational studies that explored the use of medications and their adverse effects on older people in clinical settings (including aged care facilities). Methods: an initial search of the PubMed (United State National Library of Medicine), OvidSP, EBSCOHost, ScienceDirect, Wiley Online, SAGE, and SCOPUS databases, with full text was performed, followed by an analysis of the article’s title and abstract. Additionally, MeSH (Medical Subject Headings) was used to describe the article. The initial round of the database search was based on inclusion criteria from studies that assessed tools or protocols aiming to identify the adverse effects of medications on the elderly population suffering chronic conditions or multiple co-morbidities. Two reviewers screened the retrieved papers for inclusion. The data presented in this review are in tabular forms and accompanied by a narrative summary which aligns with the review’s objectives. Results: seven studies were identified, and the extracted data from these studies were grouped according their characteristics and the auditing results of each study. Conclusion: it would be beneficial to design a comprehensive or broadly adverse drug reaction assessment tool derived from Australian data that has been used on the elderly in an Australian healthcare setting.

scholarly journals Movement-Specific Reinvestment in Older People Explains Past Falls and Predicts Future Error-Prone Movements

2021 ◽  
Vol 18 (10) ◽  
pp. 5129
Author(s):  
Lisa Musculus ◽  
Noel Kinrade ◽  
Sylvain Laborde ◽  
Melina Gleißert ◽  
Miriam Streich ◽  
...  
Keyword(s):  
Older People ◽  
Physical Performance ◽  
Physical Functioning ◽  
Daily Diary ◽  
The Elderly ◽  
Movement Behavior ◽  
Motor Training ◽  
Baseline Assessment ◽  
Motor Processing ◽  
The Past

The tendency to think about or consciously control automated movements (i.e., movement-specific reinvestment) is a crucial factor associated with falling in the elderly. We tested whether elderly people’s movement-specific reinvestment depended on their past falling history and whether it can predict future error-prone movements. In a longitudinal pre-post design, we assessed n = 21 elderly people’s (Mage = 84.38 years, SD = 5.68) falling history, movement-specific reinvestment (i.e., Movement-Specific Reinvestment Scale), and physical functioning (i.e., Short-Physical-Performance Battery). Following a baseline assessment, participants reported their movement behavior in a daily diary for 2 months, after which we assessed their movement-specific reinvestment and physical functioning again (longitudinal, pre-post design). Results revealed, first, that participants’ movement self-consciousness score was fairly stable, while their conscious-motor-processing score was less stable. Second, conscious motor processing was higher in participants who had fallen as opposed to those who had not fallen in the past. Third, conscious motor processing predicted error-prone future movement behavior reported in the daily diary. For identifying individuals who are more prone to fall, caregivers, rehabilitation staff, or doctors could apply the Movement-Specific Reinvestment Scale to screen elderly people’s psychomotor behavior. Based on conscious motor processing, monitoring cognitions could be tailored in theory-based, individual interventions involving both cognitive and motor training.

scholarly journals Identifying Tools That Assess Factors That May Lead to Adverse Effects in Australian Aged-Care Facilities: A Scoping Review

2020 ◽  
Author(s):  
Haider Saddam Qasim ◽  
Maree Simpson ◽  
Yann Guisard ◽  
Barbora de Courten
Keyword(s):  
Adverse Effects ◽  
Older People ◽  
Scoping Review ◽  
Adverse Drug Events ◽  
Assessment Tool ◽  
The Elderly ◽  
Aged Care ◽  
Inclusion Criteria ◽  
Care Facilities ◽  
Aged Care Facilities

Aim: this scoping review was designed to identify studies that assess the adverse drug reactions (ADRs) for older people in Australian aged-care facilities. This review critically evaluated each published study to identify the risk of, or actual adverse drug events in older people. Inclusion criteria: This review considered any clinical studies that examined the adverse effects of medications in older people who were living in aged-care facilities. This review considered qualitative studies, analytical studies, RCTs, descriptive cross-sectional studies, and analytic observational studies that explored the use of medications and their adverse effects on older people in clinical settings (including aged care facilities). Methods: An initial search of the PubMed, OvidSP, EBSCOHost, MEDLINE, ScienceDirect, Wiley Online, SAGE, and SCOPUS databases, with full text was performed, followed by an analysis of the article’s title and abstract. Additionally, MeSH was used to describe the article. The initial round of the database search was based on inclusion criteria from studies that assessed tools or protocols aiming to identify the adverse effects of medications on the elderly population suffering chronic conditions or multiple co-morbidities. Two reviewers screened the retrieved papers for inclusion. The data presented in this review are in tabular forms and a narrative summary which aligns with the review’s objectives. Results: Seven studies were identified, and the extracted data from these studies were grouped according their characteristics and the auditing results of each study. Conclusion: There was no comprehensive or broadly adverse drug reaction assessment tool derived from Australian data that has been used on the elderly in an Australian healthcare setting.

scholarly journals Flattening the Curve of Cognitive Decline: A Survey of Cognitive Interventions for People Living with Dementia

2020 ◽  
Vol 9 (1) ◽  
pp. 110-114
Author(s):  
Bella (Yigong) Zhang ◽  
Mark H. Chignell
Keyword(s):  
Older People ◽  
Cognitive Decline ◽  
The Elderly ◽  
Cognitive Interventions ◽  
Significant Challenge ◽  
The Past ◽  
Aging Societies

In our aging societies, slowing and managing cognitive decline has become a significant challenge for older people, caregivers, andhealthcare providers. In the past decade, there has been an explosion in productsaimed at providing cognitive interventions for the elderly in response to the growing market need. In thispaper, we present a framework for thinking about cognitive interventions, and a product typology based onthe level of technology used and the amount of tangibility/physical interactivity that products have. Weshow how current products fit within the proposed product typology framework. We also note shortfallsthat exist in validating products in terms of their claimed cognitive interventions, and in regions of theproduct technology space that deal withproducts that have low technology and low physical interactivity.

scholarly journals A survey of psychiatrists in northwest England concerning their use of maintenance electroconvulsive therapy

2007 ◽  
Vol 19 (5) ◽  
pp. 985-987 ◽  
Author(s):  
SUSAN MARY BENBOW ◽  
DAVID TENCH
Keyword(s):  
Older People ◽  
Electroconvulsive Therapy ◽  
Maintenance Treatment ◽  
Response Rate ◽  
The Elderly ◽  
Study Group ◽  
Second Stage ◽  
The Past ◽  
Practice Audit

Dr. Lim's practice audit of maintenance electroconvulsive therapy (M-ECT) in the elderly (Lim, 2006) describes a group of older people treated with M-ECT in Australia but does not describe the views of Australian psychiatrists regarding the use of this form of treatment. We explored the views of psychiatrists in northwest England regarding the use of M-ECT in the 1990s: our study group was a subset of the cohort reported in Benbow et al. (1998), namely those respondents to a first-stage questionnaire who stated that they had used M-ECT (25%) or were prepared to consider its use (67%). A second-stage questionnaire inquired specifically about practice in relation to M-ECT, defined as the regular administration of ECT in order to minimize the likelihood of further episodes of illness, and was sent to 85 individuals of whom 77 responded, giving a response rate of 87.5%. Of these respondents, 49% stated that they had not prescribed maintenance treatment within the past 10 years; 42% estimated that they had prescribed one or two courses; 8% three to four courses and 1% five to six courses. None had prescribed more than six courses, so the experience of any one individual was relatively limited.

scholarly journals The Health of Older People in Switzerland

2018 ◽  
Vol 1 (2) ◽  
pp. 5-8
Author(s):  
Chastonay P ◽  
Weber D ◽  
Mattig T ◽  
Mattig T
Keyword(s):  
Older People ◽  
Total Population ◽  
Good Health ◽  
The Elderly ◽  
Self Determination ◽  
Past Century ◽  
Public Health Importance ◽  
The Public ◽  
The Past ◽  
At Home

Over the past century, the proportion of Swiss residents aged 65 or older rose from 5.8% to 17.8%; during the same period, the proportion aged over 80 rose from 0.5% to 5.0%. Although the majority of older people in Switzerland enjoy good health, disease prevalence rises with age. Almost half (49%) of people over 65 living at home report at least one chronic illness. Among the 65- to 79-year-olds living at home, 25.2% suffer from several chronic diseases; among people in the 80s, this figure reaches 41.3%. People aged over 80 are also particularly at risk for falls (30%). In addition, between 15% and 25% of the elderly suffer from at least one mental illness. Close to 30% of healthcare costs are attributable to people over the age of 75, who make up only 8% of the total population. Given the public health importance of the issue a health promotion project targeting the elderly – the VIA Project -, based on successful local programs, is being implemented throughout the country. The overall goal of the VIA project is to promote the health of older people and to strengthen their self-determination and independence.

scholarly journals Comunidades Amazônicas Revivendo Experiências na Terceira Idade em Realidade Virtual no Interior do Amazonas

2020 ◽  
Author(s):  
Bárbara Vitória Duarte Nogueira ◽  
Fabiann Matthaus Dantas Barbosa
Keyword(s):  
Virtual Reality ◽  
Older People ◽  
Social Relations ◽  
Elderly Population ◽  
Daily Life ◽  
Three Dimensional ◽  
The Elderly ◽  
Digital Inclusion ◽  
The Past ◽  
Time Space

Today, technology is present in the life of much of society, offering different forms of interaction, showing new ways of understanding, perception and learning. However, in the daily life of the elderly there are still barriers that hinder digital inclusion, this becomes clearer in places where technology is not evident, such as in the interior of the Amazon. The use of virtual reality (VR) has grown in society in different segments, so that its application has brought new immersive experiences in various areas. With the objective of expanding digital inclusion with older people living in Labrea - AM, this project aimed to provide the elderly population in rural and riverside communities with opportunities to reconstruct memories lived in the past through old images experiencing new experiences in a three-dimensional manner. through virtual reality. For this, cardboard scrap collections were made for the creation of VR glasses, as well as the making of devices using recycled materials. With this, the project was able to serve as a benefit in the reconstruction of experiences located in time, space and the whole of social relations, besides being a guide of information and exchange of experiences transmitted to the younger ones.

FEATURES OF SOCIALIZATION OF OLDER PEOPLE IN MODERN SOCIETY

2021 ◽  
Vol 1 (4) ◽  
pp. 139-144
Author(s):  
A. E. BIRYUKOV ◽  
◽  
◽  
Keyword(s):  
Quality Of Life ◽  
Statistical Analysis ◽  
Older People ◽  
Social Services ◽  
Modern Society ◽  
The Elderly ◽  
Aging Society ◽  
Older Citizens ◽  
Constructive Interaction

The article is devoted to the problem of socialization of older citizens in an aging society. Based on a statistical analysis, the article identifies the basic problems of socialization of the elderly in Russia, the directions of the state strategy in the context of the socio-economic crisis for the development of a system of social services for the older generation, improving their quality of life and active longevity. It was found that the most intensive socialization occurs in the process of providing social and social and medical services. It was determined that for the successful socialization of older people, the importance of services related to maintaining healthy and socially active longevity, organizing everyday life and leisure, constructive interaction with relatives is high.

scholarly journals Cognitive toxicity of drugs used in the elderly

2001 ◽  
Vol 3 (3) ◽  
pp. 181-190
Keyword(s):  
Cognitive Impairment ◽  
Adverse Effects ◽  
Older People ◽  
The Elderly ◽  
Heterogeneous Population ◽  
Older Individuals ◽  
Wide Range ◽  
Cognitive Disturbances ◽  
Toxicity Of Drugs ◽  
Package Labeling

The aged are an extremely heterogeneous population that is growing worldwide, included are healthy and agile individuals in their early sixties, as well as an increasing number of people over the age of 35. Pharmacotherapy is expected to continue its prominent role in the medical management of a wide range of conditions that affect older people. Adverse consequences of all kinds complicate the use of medications, and such events seem to increase in incidence with polypharmacy. Cognitive impairment can occur during the course of treatment with a wide range of medications and can have a variety of presentations, Both the number of concurrent medications that older individuals routinely use and physiologic changes in these patients render them more susceptible to developing cognitive toxicity. Most of the frequently implicated medications carry documentation of their ability to cause cognitive disturbances in their package labeling, suggesting that the level of vigilance for adverse effects during the course of their use should always be high. Such caution can be used to guide appropriate drug treatment of the aged so that clinicians do not need to opt for undertreatment to avoid toxicity.

Sign in / Sign up

Export Citation Format

Share Document