scholarly journals Quality of Life and its associated factors amongst Patients with Brain Tumors at a Tertiary Care Hospital in Pakistan: An Analytical Cross-Sectional Study

Author(s):  
Nida Zahid ◽  
Russell Seth Martin ◽  
Wajeeha Zahid ◽  
Iqbal Azam ◽  
Aneesa Hassan ◽  
...  

Abstract Introduction Despite quality of life (QoL) being recognized as an important outcome in neuro-oncology, there is a lack of research from Pakistan where sociocultural differences may influence QoL. This study aimed to measure the QoL in patients with primary brain tumors (PBTs), and assess its association with mental health outcomes, resilience, and social support. Methods A cross-sectional survey was conducted among primary brain tumor patients. QoL was measured using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire. Resilience was assessed by Wagnild and Young's Resilience Scale, mental health outcomes using Hospital Anxiety and Depression Scale, and social support using the Enriched Social Support Instrument. Results Our study included a total of 250 patients, with median age of 42 years (range 33-54 years). The mean global QoL of the sample was 75.73 ± 14.9. On multivariable linear regression, global QoL was inversely associated with no or low income, having hypertension (-5.77), currently using a urine catheter (-15.33), having low social support (-28.16) suffering from mild (-9.88) or symptomatic (-17.59) depression, or mild anxiety (-7.11), while resilience (0.28) demonstrated a significant positive association. Conclusion The quality of life of patients with primary brain tumors in Pakistan is a function of clinical factors such as comorbid disease and use of a urinary catheter, social factors such a family income and social support, and psychological factors such as mental illness and resilience. Our findings may be of use in the development of QoL-improving interventions within the sociocultural setting of Pakistan.

2021 ◽  
Author(s):  
Nida Zahid ◽  
Russell Seth Martins ◽  
Wajeeha Zahid ◽  
Iqbal Azam ◽  
Aneesa Hassan ◽  
...  

Abstract IntroductionDespite quality of life (QoL) being recognized as an important outcome in neuro-oncology, there is a lack of research from Pakistan where sociocultural differences may influence QoL. This study aimed to measure the QoL in patients with primary brain tumors (PBTs), and assess its association with mental health outcomes, resilience, and social support.MethodsA cross-sectional survey was conducted among primary brain tumor patients. QoL was measured using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire. Resilience was assessed by Wagnild and Young's Resilience Scale, mental health outcomes using Hospital Anxiety and Depression Scale, and social support using the Enriched Social Support Instrument.ResultsOur study included a total of 250 patients, with median age of 42 years (range 33-54 years). The mean global QoL of the sample was 75.73 ± 14.9. On multivariable linear regression, global QoL was inversely associated with no or low income, having hypertension (-5.77), currently using a urine catheter (-15.33), having low social support (-28.16) suffering from mild (-9.88) or symptomatic (-17.59) depression, or mild anxiety (-7.11), while resilience (0.28) demonstrated a significant positive association. Conclusion The quality of life of patients with primary brain tumors in Pakistan is a function of clinical factors such as comorbid disease and use of a urinary catheter, social factors such a family income and social support, and psychological factors such as mental illness and resilience. Our findings may be of use in the development of QoL-improving interventions within the sociocultural setting of Pakistan.


Work ◽  
2020 ◽  
Vol 67 (2) ◽  
pp. 285-293
Author(s):  
Stefanie Mache ◽  
Monika Bernburg ◽  
David Groneberg ◽  
Volker Harth

BACKGROUND: Previous research studies have demonstrated that neuro-enhancement, the use of legal or illegal drugs by healthy individuals to improve their job performance, is practiced among employees. Researchers discussed possible reasons for employees to consider the use of substances for neuro-enhancement. OBJECTIVE: The aim of this study was to identify the prevalence of usage and motives for practicing neuro-enhancement among a sample of German junior physicians. The secondary objective was to determine associations between neuro-enhancement, mental health outcomes and quality of life. METHODS: This cross-sectional study included an online survey to analyze junior physicians’ neuro-enhancement stimulant use and their motives for usage (n = 873). Second, mental health outcomes and quality of life were assessed. Descriptive and analytic (Kruskal Wallis test, logistic regression) statistics were obtained. RESULTS: Of the 873 junior physicians, 18% reported having used stimulants for neuro- enhancement. 8% of the physicians have taken prescription stimulants (e.g. modafinil) or illicit drugs (e.g. cannabis) at least once in their lifetime. The most common reasons for taking stimulants were to enhance concentration, to relax and to increase alertness. Neuro-enhancement was associated with emotional exhaustion (p < 0.01), lower quality of life (p < 0.05) and work-related stress (p < 0.01). CONCLUSIONS: Our study results give an overview on the actual situation regarding frequency and motives for taking performance-enhancing substances. The prevalence rate was low in comparison to current public debates. Decreasing the prevalence of neuro-enhancement among physicians requires the implementation of strategies targeting stress reduction and workload management.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Nida Zahid ◽  
Russell Seth Martins ◽  
Wajeeha Zahid ◽  
Wardah Khalid ◽  
Iqbal Azam ◽  
...  

Abstract Introduction This study translated and validated the Urdu version of the European Organization for Research and Treatment of Cancer Quality of Life (QoL) Questionnaire (EORTC QLQ-C30) and Brain Module (QLQ-BN20) amongst patients with primary brain tumors (PBT) in Pakistan, and assessed the correlation of QoL with resilience, depression, and anxiety. Methods Translation of the EORTC QLQ-C30 and QLQ-BN20 was performed as per EORTC guidelines. A survey comprising of Urdu translations of EORTC QLQ-C30, QLQ-BN20, Wagnild and Young Resilience Scale (RS-14) and Hospital Anxiety and Depression Scale was administered to patients with PBT at a tertiary care hospital in Pakistan. Reliability (via Cronbach alpha), content validity index (CVI) scores, construct validity, and inter-scale correlations were assessed. Results Our sample consisted of 250 patients with PBT, most commonly glioma (46.8%) and meningioma (21.2%). All patients were able to understand the Urdu translations. The Cronbach alphas for the QLQ-C30 and the QLQ-BN20 were 0.860 and 0.880, respectively. The CVI scores for clarity and relevance were high for both the EORTC QLQ-C30 (0.98 and 0.96, respectively) and the QLQ-BN20 tool (0.81 and 0.95, respectively). The global QoL domain (EORTC QLQ-C30) showed significant positive correlations with resilience (r = 0.422), and significant negative correlations with depression (r =  − 0.541) and anxiety (r =  − 0.502). Strong inter-scale correlations were observed between physical functioning and insomnia (r =  − 0.690) and role functioning and insomnia (r =  − 0.641). Conclusion Our study confirms the Urdu versions of the EORTC QLQ-C30 and QLQ-BN20 as valid clinical tools for the measurement of QoL in primary brain tumors patients within the cultural and socioeconomic context of Pakistan.


2021 ◽  
pp. 136843022110408
Author(s):  
Kyle L. Benbow ◽  
Brianna L. Smith ◽  
Karlee J. Tolbert ◽  
Jason C. Deska ◽  
Jonathan W. Kunstman

People often believe Black individuals experience less social pain and require less social support to cope with distress than White individuals (e.g., Deska, Kunstman, Lloyd, et al., 2020). However, researchers have not tested whether biases in third-person pain judgments translate to first-person experiences with social pain minimization. For example, do Black individuals feel their social pain is underrecognized to a greater extent than White individuals? The current work tested whether Black individuals felt their social pain was minimized more than White individuals and if the experience of social pain minimization was related to worse mental health and greater life stress. Data from two cross-sectional, correlational studies provide initial support for these predictions ( Ntotal = 1,501). Black participants felt their social pain was minimized more than White participants and this race difference in social pain minimization was associated with worse mental health and greater life stress. These results suggest that Black individuals feel their pain is underrecognized and this experience of social pain minimization is related to worse mental health outcomes.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 306-307
Author(s):  
Hallie Nuzum ◽  
Katherine Dorociak ◽  
Shirit Kamil-Rosenberg ◽  
Peter Louras ◽  
Mandana Mostofi ◽  
...  

Abstract Objective and subjective cognitive function have been associated with decreased quality of life and increased psychological distress in older adults. The present study examined relations of objective and subjective cognition with quality-of-life and mental-health outcomes in individuals with amnestic mild cognitive impairment (aMCI). The sample included 98 older adults with aMCI (92.5% male, age = 70.9±9.2 years). Measures included objective cognition (i.e., attention, memory, language, visuospatial abilities, processing speed, executive function, and overall), subjective memory (Multifactorial Memory Questionnaire [MMQ]), quality of life (Dementia Quality of Life [DQoL]), and mental health (Geriatric Depression Scale, Geriatric Anxiety Inventory, and Penn State Worry Questionnaire). Objective and subjective cognition were weakly correlated (range |r| = .00–.23). Objective cognitive measures were largely uncorrelated with quality of life or mental health, with only two significant (p &lt; .05) correlations between Processing Speed and Worry (r = -.24), and Overall Cognition and DQoL Aesthetics (r = .20). Subjective cognition was more strongly correlated with quality of life, including significant (p &lt; .01) correlations between MMQ Abilities and DQoL Negative Affect (r = -.38), and MMQ Contentment and DQoL Positive Affect (r = .28). Additionally, MMQ Contentment and Abilities were significantly (p &lt; .01) negatively correlated with all three mental-health outcomes (range |r| = .28–.43). This study demonstrated that subjective memory, particularly affect and self-appraisal regarding one’s memory capabilities, is more closely related to quality-of-life and mental-health outcomes than objective cognitive performance in an aMCI sample, and, therefore, may represent important targets for intervention.


2020 ◽  
Vol 59 (4) ◽  
pp. 202-210
Author(s):  
Jelena Kovačević ◽  
Maja Miškulin ◽  
Matea Matić Ličanin ◽  
Josip Barać ◽  
Dubravka Biuk ◽  
...  

AbstractIntroductionThe loss of quality of life is the major consequence following a non-fatal road traffic accident (RTA). Previous research regarding quality of life did not include uninjured RTA survivors. The research aim was thus to evaluate the quality of life of the RTA survivors regardless of whether or not they sustained injures, and to identify factors associated with decreased quality of life after the RTA.MethodsA cohort of 200 RTA survivors with and without injuries was followed after experiencing an RTA. The quality of life and mental health outcomes were assessed 1 month following RTA. A vast range of sociodemographic, pre-RTA health-related, RTA related, RTA injury-related, compensation-related factors and mental health outcomes were investigated.ResultsDecreased quality of life following an RTA showed an association with the low socioeconomic status of the RTA victims, poor pre-RTA health, injury-related factors, compensation-related factors and psychological disorders after the RTA.ConclusionsIdentifying predictors of decreased quality of life following an RTA will enable planning interventions targeting the most important factors that influence recovery of RTA victims. Assessing and recording of self-reported quality of life should be a part of the routine protocol in RTA survivors’ health-care.


2016 ◽  
Vol 8 (10) ◽  
pp. 24 ◽  
Author(s):  
Nourossadat Kariman ◽  
Maliheh Amerian ◽  
Padideh Jannati ◽  
Fatemeh Salmani ◽  
Mazlumeh Hamzekhani

<p><strong>Background and Objectives:</strong> Normal fertility follows a set of biological, social and cultural rules and regulations; controlled fertility, however, follows the rules and regulations of the family. The present study was therefore conducted to identify the factors influencing the first childbearing decision-making in women living in Shahroud, Iran, in 2014. <strong></strong></p><p><strong>Materials and Methods:</strong> The present descriptive cross-sectional study was conducted on 300 randomly-selected pregnant women admitted to health centers in Shahroud. The utilized data collection tools included a demographic and obstetrics questionnaire, a quality of life questionnaire, the ENRICH Marital Satisfaction Scale, the Snyder Hope Scale and the Multidimensional Scale of Perceived Social Support. Data were analyzed in SPSS-17 and the direct or inverse effects of the factors influencing the first childbearing decision-making were examined in AMOS-20.<strong></strong></p><p><strong>Results:</strong> The results obtained revealed marital age to have the highest degree of correlation with the first childbearing decision-making in women (r=0.90 and P&lt;0.001).Once the statistically insignificant paths were eliminated, marital age was found to have the highest direct effect (β=0.63) on the first childbearing decision-making, followed by other factors including economic status (β=0.07), hopefulness (β=-0.07) and quality of life (β=-0.05). The inverse effects of marital age (β=0.01), social support (β= -0.01) and quality of life (β=-0.01) on the first childbearing decision-making were found to be significant in women (P&lt;0.001).<strong></strong></p><p><strong>Conclusion:</strong> Many factors are involved in the process of childbearing decision-making, including individual factors (marital age, hopefulness and quality of life), familial factors (marital satisfaction) and social factors (social support). Healthcare institutions and policymakers should adopt strategies that can help couples bear their desired number of children within an appropriate time frame through ameliorating their social, economic and familial conditions.<strong></strong></p>


Author(s):  
Rodolfo Buselli ◽  
Martina Corsi ◽  
Sigrid Baldanzi ◽  
Martina Chiumiento ◽  
Elena Del Lupo ◽  
...  

The novel coronavirus disease 2019 (COVID-19) is a global pandemic spreading worldwide, and Italy represented the first European country involved. Healthcare workers (HCWs) facing COVID-19 pandemic represented an at-risk population for new psychosocial COVID-19 strain and consequent mental health symptoms. The aim of the present study was to identify the possible impact of working contextual and personal variables (age, gender, working position, years of experience, proximity to infected patients) on professional quality of life, represented by compassion satisfaction (CS), burnout, and secondary traumatization (ST), in HCWs facing COVID-19 emergency. Further, two multivariable linear regression analyses were fitted to explore the association of mental health selected outcomes, anxiety and depression, with some personal and working characteristics that are COVID-19-related. A sample of 265 HCWs of a major university hospital in central Italy was consecutively recruited at the outpatient service of the Occupational Health Department during the acute phase of COVID-19 pandemic. HCWs were assessed by Professional Quality of Life-5 (ProQOL-5), the Nine-Item Patient Health Questionnaire (PHQ-9), and the Seven-Item Generalized Anxiety Disorder scale (GAD-7) to evaluate, respectively, CS, burnout, ST, and symptoms of depression and anxiety. Females showed higher ST than males, while frontline staff and healthcare assistants reported higher CS rather than second-line staff and physicians, respectively. Burnout and ST, besides some work or personal variables, were associated to depressive or anxiety scores. The COVID-19 pandemic represents a new working challenge for HCWs and intervention strategies to prevent burnout and ST to reduce the risk of adverse mental health outcomes are needed.


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