Adherence to Mediterranean-DASH Intervention for Neurodegenerative Delay Diet Can Decreased Risk of Age Associated Poor Muscle Strength; A Cross- Sectional from Kurdish Cohort Study

2022 ◽  
Author(s):  
Yahya Pasdar ◽  
Shima Moradi ◽  
Saman Saedi ◽  
Behrooz Hamzeh ◽  
Farid Najafi
Keyword(s):  
Cohort Study ◽  
Muscle Strength ◽  
Lower Risk ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Cross Sectional ◽  
Age Related ◽  
Unhealthy Diet ◽  
Mind Diet

Abstract The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet aims to reduce dementia and the decline in brain health that often occurs as people get older. Loss of muscle strength (sarcopenia) is a geriatric syndrome that has associated with the loss of skeletal muscle mass and strength. The current study aimed to investigate the association between adherence to MIND diet and decrease the risk of age-associated poor muscle strength. This cross-sectional study was performed using data from Ravansar's non-communicable diseases (RaNCD) cohort study on 3181 adults (48.5% men) aged 35–65 years. The dietary intake of the studied participants was assessed by the use of a 114-item food frequency questionnaire (FFQ) developed by RaNCD cohort study. The MIND diet and the major dietary patterns were computed based on their dietary intake and three dietary patterns were identified including plant-based diet, high protein diet, and unhealthy diet. Hand grip strength (HGS) was measured using a hand-held hydraulic handgrip dynamometer and poor HGS was defined as HGS less than 32.8 and 20.5 kg in men and women, respectively. We found that greater adherence to MIND diet was associated with lower risk of poor HGS (OR: 0.65; CI 95%: 0.51-0.83). Furthermore, participants who were in third tertiles of plant- based and high protein diet were more likely 37% and 33% lower risk of poor HGS (OR: 0.63; CI 95%: 0.5-0.79), (OR: 0.67; CI 95%: 0.54-0.84), respectively. On the other hand, greater following to unhealthy diet was related to higher risk of poor HGS (OR: 1.39; CI 95%: 1.11-1.74). Overall, our findings provide that adhere to plant- based and high protein diet, as well as MIND diet had protective effects on age related poor HGS, while adherence to unhealthy diet can developed age related poor HGS.

scholarly journals Monoclonal antibodies used in immunocytochemical localization by electron microscopy of carbamoyl phosphate synthetase I in liver from rats fed high-protein diets.

1987 ◽  
Vol 35 (8) ◽  
pp. 897-907 ◽  
Author(s):  
A Martinez-Ramon ◽  
E Knecht ◽  
S Grisolía
Keyword(s):  
Electron Microscopy ◽  
Monoclonal Antibodies ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Carbamoyl Phosphate Synthetase ◽  
Carbamoyl Phosphate ◽  
Cross Sectional ◽  
High Protein Diets ◽  
Protein Diets

Carbamoyl phosphate synthetase I (CPS-I) is the most abundant protein of rat liver mitochondria. Biochemical measurements in liver homogenates have shown that the liver from rats fed a high-protein diet contains more CPS-I per gram tissue protein than controls. However, there is no information on changes in the intact tissue at the cellular and mitochondrial level. Therefore, monoclonal antibodies to beef liver CPS-I were produced by the hybridoma technique. Four clones, C-241/1A, B, C, and D secreted immunogammaglobulin (IgG) IgG1. Using C-241/C, we measured by electron microscopy immunogold procedures the labeling of CPS-I in mitochondria from liver of rats fed high protein (casein, 50 and 80% of total food intake) diets. CPS-I (expressed as gold particles/micron2 of mitochondrial cross-sectional area) was greater than in mitochondria from control rats (20% casein diet), whether the rats were fed for 1, 6, or 14 months on the high-protein diets. The immunocytochemical measurements shown here demonstrate that the increase in the level of CPS-I in high-protein diets is a reflection of both the larger number of CPS-I molecules per mitochondrial area and the larger proportion of the total hepatocyte volume occupied by mitochondria. Similar measurements were carried out with glutamate dehydrogenase (GDH) using previously characterized monoclonal antibodies. No differences in GDH labeling were found with high-protein diets. Interestingly, when mitochondria from hepatocytes of rats fed a high-protein diet were divided into two subpopulations on the basis of mitochondrial cross-sectional size (i.e., greater or less than 0.7 micron2), the large mitochondria had 1.2 times more CPS-I and 0.8 times less GDH than the small mitochondria nearby.

scholarly journals Major Dietary Patterns in Relation to Chronic Low Back Pain; a Cross- sectional Study from RaNCD Cohort

2021 ◽  
Author(s):  
Yahya Pasdar ◽  
Behrooz Hamzeh ◽  
Sheno Karimi ◽  
Shima Moradi ◽  
Sahar Cheshmeh ◽  
...  
Keyword(s):  
Cohort Study ◽  
Low Back Pain ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
High Protein Diet ◽  
Cross Sectional Study ◽  
High Protein ◽  
Low Back ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Chronic low back pain (LBP) is the most common musculoskeletal pain that affects a person's daily activities. This present study aimed at evaluating the relationship between major dietary pattern and Chronic LBP. Methods This cross- sectional study was applied using data from Ravansar non- communicable diseases (RaNCD) cohort study. Chronic LBP was diagnosed by the RaNCD cohort study physician. Dietary patterns were evaluated by principal component analysis. The three identified dietary patterns included: 1) vegetarian dietary pattern which included vegetables, whole grain, legumes, nuts, olive, vegetable oil, fruits, and fruit juice; 2) high protein diet related to higher adherence to red and white meat, legumes, nuts, and egg; and 3) unhealthy dietary pattern characterized with higher intake of salt, sweet, dessert, hydrogenated fat, soft drink, refined grain, tea, and coffee. Results 22.5% of participants had chronic LBP Higher following high protein dietary pattern was associated with lower risk of chronic LBP in crude (OR: 0.79, 95% CI: 0.69–0.9) and adjusted model (for age, sex, smoking, drinking, diabetes, physical activity, and body mass index) (OR: 0.84, 95% CI: 0.72–0.97). In addition, after controlling for the mentioned potential confounders, participants in the highest category of unhealthy dietary pattern were higher at risk of chronic LBP compared with those in the lowest category (OR: 1.13, 95% CI: 1.01–1.32). Conclusions Higher adherence to high protein diet significantly the decreased risk of chronic LBP prevalence. In addition, we found that following unhealthy dietary pattern was associated with higher risk of chronic LBP.

scholarly journals Low carbohydrate-high protein diet and incidence of cardiovascular diseases in Swedish women: prospective cohort study

BMJ ◽  
2012 ◽  
Vol 344 (jun26 3) ◽  
pp. e4026-e4026 ◽  
Author(s):  
P. Lagiou ◽  
S. Sandin ◽  
M. Lof ◽  
D. Trichopoulos ◽  
H.-O. Adami ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiovascular Diseases ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Low Carbohydrate

scholarly journals Low-carbohydrate, high-protein diet score and risk of incident cancer; a prospective cohort study

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Lena Maria Nilsson ◽  
Anna Winkvist ◽  
Ingegerd Johansson ◽  
Bernt Lindahl ◽  
Göran Hallmans ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Incident Cancer ◽  
Low Carbohydrate ◽  
Diet Score

scholarly journals High-Protein Diet Containing Dairy Products is Associated with Low Body Mass Index and Glucose Concentrations: A Cross-Sectional Study

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1384
Author(s):  
Bruna M. Giglio ◽  
Valeska I. R. Duarte ◽  
Ana Flávia Galvão ◽  
Ana Clara B. Marini ◽  
Raquel M. Schincaglia ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Body Mass ◽  
Dairy Products ◽  
High Protein Diet ◽  
Cross Sectional Study ◽  
High Protein ◽  
Protein Diet ◽  
Sectional Study ◽  
Cross Sectional

The aim was to evaluate whether the ingestion of a high protein diet containing dairy protein is associated with anthropometric indicators of adiposity and blood glucose. Methods: A cross-sectional study was conducted with volunteers of 20–89 years of age who performed leisure physical activity. We assessed dietary intake, body mass index (BMI), waist circumference (WC), triceps skinfold thickness (TSFT), random blood glucose as well as sociodemographic and behavioral variables. Results: A total of 418 individuals were evaluated. The consumption of a high-protein diet (1.80 ± 0.49 g/kg/day) was found in 37.8% of individuals, which showed lower BMI, WC, TSFT and blood glucose concentrations compared to those with a low-protein diet (0.56 ± 0.18 g/kg/day). Dairy products consumption was inversely associated with BMI when adjusted for sex and age (odds ratio (OR): 0.79, 95% confidence interval (CI): 0.68–0.93, p = 0.004) and by sex, age, fiber and energy (OR: 0.79; 95% CI: 0.67–0.92; p = 0.004), and with blood glucose when adjusted for sex and age (OR: 0.86; 95% CI: 0.74–0.99; p = 0.042). Cheese consumption was inversely associated with blood glucose when adjusted for sex and age (OR: 0.73, 95% CI: 0.55–0.96, p = 0.023) and by sex, age, calories and fibers (OR: 0.74, 95% CI: 0.56–0.98, p = 0.036). Two portions of cheeses/day reduced the risk of having high blood glucose levels by approximately 80%. Conclusion: A high-protein diet containing dairy food, in particular two servings of cheese, was associated with low BMI and random glucose concentration.

scholarly journals A high-protein diet increases faecal IgA concentrations in baby pigs

2008 ◽  
Vol 67 (OCE5) ◽  
Author(s):  
F. Vitari ◽  
A. Morise ◽  
M. Formal ◽  
C. Garcia ◽  
K. Mace ◽  
...  
Keyword(s):  
High Protein Diet ◽  
High Protein ◽  
Protein Diet

scholarly journals Measurement of the Intestinal pH in Mice under Various Conditions Reveals Alkalization Induced by Antibiotics

Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 180
Author(s):  
Kouki Shimizu ◽  
Issei Seiki ◽  
Yoshiyuki Goto ◽  
Takeshi Murata
Keyword(s):  
Antibiotic Treatment ◽  
High Protein Diet ◽  
Intestinal Bacteria ◽  
High Protein ◽  
Protein Diet ◽  
Germ Free ◽  
Treatment Regimens ◽  
Ph Values ◽  
Specific Pathogen ◽  
The Stability

The intestinal pH can greatly influence the stability and absorption of oral drugs. Therefore, knowledge of intestinal pH is necessary to understand the conditions for drug delivery. This has previously been measured in humans and rats. However, information on intestinal pH in mice is insufficient despite these animals being used often in preclinical testing. In this study, 72 female ICR mice housed in SPF (specific pathogen-free) conditions were separated into nine groups to determine the intestinal pH under conditions that might cause pH fluctuations, including high-protein diet, ageing, proton pump inhibitor (PPI) treatment, several antibiotic treatment regimens and germ-free mice. pH was measured in samples collected from the ileum, cecum and colon, and compared to control animals. An electrode, 3 mm in diameter, enabled accurate pH measurements with a small amount of gastrointestinal content. Consequently, the pH values in the cecum and colon were increased by high-protein diet, and the pH in the ileum was decreased by PPI. Drastic alkalization was induced by antibiotics, especially in the cecum and colon. The alkalized pH values in germ-free mice suggested that the reduction in the intestinal bacteria caused by antibiotics led to alkalization. Alkalization of the intestinal pH caused by antibiotic treatment was verified in mice. We need further investigations in clinical settings to check whether the same phenomena occur in patients.

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