scholarly journals Genomic Insight Into 21 Hypervariable Molecular Markers in The Population of Lower Himalayan Geographical Province Himachal Pradesh, India

Author(s):  
Arun Sharma ◽  
Ankit Srivast ◽  
Vivek Sahajpal ◽  
R Kumawat ◽  
Shivani Dixit ◽  
...  

Abstract A natural geographical barrier between Tibetan plateau and south Asian countries, the Himalayan Mountain range, serves as a natural barrier between these regions for genetic flow. This has lead to vast genomic divergence among the population residing in Indian Himalayan region..This study was designed with an aim to decipher the genomic diversity and molecular characterization of 21 hypervariable molecular markers in the population of geographical province of Himachal Pradesh in the lower Himalayan region. Randomly selected 401 unrelated individuals native of the lower Himalayan geographical region were included for this study. 21 hypervariable molecular markers included in the PowerPlex® 21 system were amplified and genotyped. A total of 246 alleles and 12.3 (SE 0.927) private alleles per locus were observed. Population differentiation analysis revealed that the studied population showed a genetic affinity with the population of North India, North-west India, Central India, and Uttar Pradesh rather than the population of East India, South India, East Asia, and West Asia. Heterozygosity at the studied loci was found in the range of 0.686 to 0.920. The unite discrimination power (PD) and exclusion power (PE) was found to be 1 and 0.999999998073765 respectively. The unite value of matching probability and typical paternity index was found to be 9.33x10-26 and 5.05x108 respectively for the studied population. All the tested loci were found in Hardy Weinberg Equilibrium (HWE) expectations. Overall the studied population exhibited a great extent of genomic diversity and had a greater genetic affinity with Indo-European speakers rather than Dravidian and Tibeto-Burman speakers.

2020 ◽  
pp. 171-174
Author(s):  
Ashwini Kumar Dixit ◽  
Mery Aradhna Kerketta

This article reports the occurrence of the thalloid liverwort Cyathodium denticulatum Udar et Srivastava was collected first time from the Achanakmar – Amarkantak Biosphere Reserve (AABR) Bilaspur, Chhattisgarh. It is shown that Cyathodium denticulatum a narrow Himalayan endemic has been reported earlier from Darjeeling, India. There is no record of its occurrence from central India. Cyathodium denticulatum is a rare species known only from eastern Himalayan region. A key to related Indian taxa and taxonomic description is provided.


Author(s):  
Kushel Verma ◽  
Sanjeev Kumar ◽  
Vaishali Sharma

Background: There are a limited number of studies regarding the prevalence of hepatitis B, hepatitis C and HIV infections among the drug addicts in Himachal Pradesh; C virus (HCV) infection in north India especially Himachal with very high rates of substance abuse. The present study was attempted to study the prevalence of hepatitis C among the injectable drug users, which is more important in a country like India where viral hepatitis is estimated to be among the top ten causes of deaths.Methods: A study was conducted in 2019-2020 (July-April). HBsAg, anti-HBs, anti-HCV and anti-HIV tests in 235 drug addicts were studied. Urine samples obtained from drug addicts were analyzed for cannabis, opiate and cocaine metabolites.Results: The subjects included were 235 IDUs who were opioid dependent. All the 235 drug users were males, and their mean age was 30.69±9.494 years; 112 (47.7%) of them were in the age group ranging 20 - 29 years (p <0.05). Of 235 drug addicts, 113 (48.1%) and 115 (48.9%) were only cannabis and opiate users, respectively. The frequencies of HBsAg, anti-HBs and anti-HCV among drug addicts were 2.6%, 38.3%, and 9.4%, respectively.Conclusions: The obtained results showed that HCV infection was an alarming problem among opiate users in this part of Himachal. It is suggested to rapidly diagnose the infected persons; thus preventive measures and appropriate control may limit further transmission of these infections.


2019 ◽  
Vol 116 (7) ◽  
pp. 1246 ◽  
Author(s):  
Trisha Roy ◽  
Suresh Kumar ◽  
Lekh Chand ◽  
D. M. Kadam ◽  
Bankey Bihari ◽  
...  

2018 ◽  
Vol 22 (1) ◽  
pp. 29-45
Author(s):  
Fabio Silva

This paper applies a combined landscape and skyscape archaeology methodology to the study of megalithic passage graves in the North-west of the Iberian Peninsula, in an attempt to glimpse the cosmology of these Neolithic Iberians. The reconstructed narrative is found to be supported also by a toponym for a local mountain range and associated folklore, providing an interesting methodology that might be applied in future Celtic studies. The paper uses this data to comment on the ‘Celticization from the West’ hypothesis that posits Celticism originated in the European Atlantic façade during the Bronze Age. If this is the case, then the Megalithic phenomenon that was widespread along the Atlantic façade would have immediately preceded the first Celts.


2021 ◽  
Author(s):  
Ratna Patel ◽  
Strong P Marbaniang ◽  
Shobhit Srivast ◽  
Pradeep Kumar ◽  
Shekhar Chauhan

Abstract Background: Most of childbirth complications usually arise during the time of delivery and are difficult to predict, but can be effectively managed through delivery at the health facility equipped with skilled birth attendants placed in an enabling environment. Despite many efforts put by the Government to reduce maternal and neonatal deaths through institutional birth deliveries, statistics suggest that these deaths are still very high in India. This study sought to determine the prevalence of home births and identifying the factors influencing women choice.Methods: Data from the National Family Health Survey (NFHS) conducted during 2005-06 and 2015-16 was used in the study. The respondents were women 15-49 years, a sample of 36,850 and 1, 90,898 women from two time period were included in the study. Multivariate logistic regression was used to determine the factors influencing home delivery. Results: Women’s who give birth at home has reduced by 39.6% from 58.5%. As compared to women below 18 years, those who were above 25 years were less likely to give birth at home [OR: 0.57; CI: 0.49-0.68] and [OR: 0.76; CI:0.70-0.82]. Women with full ANC visit were less likely to give birth at home as compare to women with no ANC visit [OR: 0.34; CI: 0.28-0.41] and [OR: 0.41; CI: 0.38-0.45]. In central India the odds of delivering babies at home was high in 2005-06 [OR: 1.15; CI: 1.01-1.32] whereas in 2015-16 the situation was opposite [OR: 0.92; CI: 0.87 -0.98] in reference to women from north India. Conclusion: There is a need to promote institutional deliveries, special focus to be given to poor women, women with higher parity, uneducated women, and rural women. Much work needs to be done in the rural parts of the country as rural women were more likely to opt for home delivery than their counterparts.


Author(s):  
Naveen Thakur ◽  
Reetika Bhadwal ◽  
Jitender Kumar ◽  
Manpreet Kaur ◽  
Rohit Mehra ◽  
...  
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Author(s):  
Saurav Negi ◽  
Neeraj Anand ◽  
Shantanu Trivedi

This paper examines the factors that impact the quality of tomatoes during the transportation through the supply chain. This is motivated by the criticality transportation in north India region. Primary data was collected through a survey using a questionnaire with responses from 140 transporters from the Himachal Pradesh and Uttarakhand states of India. The data were analyzed using factor analysis to identify the factors that are impacting the quality of tomatoes during the transportation stage. Based on the analysis, three factors were identified that impact quality: Operational, Preservation and Infrastructure. The identification of these factors will benefit the stakeholders involved in the process of decision-making, like the state government, food processing units, transporters, and the farmers. This will help us to understand the current status of transportation and related issues and challenges which enable them to make better planning and management to improve efficiency in the transportation stage of the supply chain.


2019 ◽  
pp. 3-53
Author(s):  
Pratyay Nath

This chapter studies the Mughal conquest of the heart of North India. It argues that the heterogeneous geography of this landmass shaped the course and nature of military engagements. The vast open plains of the Punjab and the Gangetic Basin allowed large-scale cavalry manoeuvres. Hence, the Mughals were able to engage their adversaries in a number of battles and skirmishes here. In contrast, the broken terrain of the forested highlands of central India restricted free movement of troops and encouraged fortress warfare. For this reason, Mughal expansion entailed a greater number of sieges here. This environmental heterogeneity also made it impossible for either cavalry or firearms to spearhead Mughal military conquests uniformly or single-handedly. Thus, even within the fairly contiguous region that was to eventually comprise the political heartland of the Mughal empire, the natural environment left a deep imprint on the conduct of warfare and the course of empire-formation.


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