Secondhand Smoke Exposure, Diabetes, Elevated Glucose Level Are Risk Factors for Uterine Cervical Cancer: A Cross-Sectional Study From the Korea National Health and Nutrition Examination Survey (2010-2018)

Abstract Background: Human papilloma virus infection and tobacco smoking are the major risk factors for cervical cancer. There are limited studies searching other risk factors for cervical cancer and the results are not consistent. This study investigated the relations between cervical cancer and possible risk factors, including secondhand cigarette smoke exposure, diabetes, work schedule. Methods: In this cross-sectional study, 29,557 women completed a cervical cancer questionnaire and were selected using 2010–2018 data from the Korea National Health and Nutrition Examination Survey. Details in secondhand smoke exposure, diabetes, work schedule were assessed from participants’ health interviews and blood test results were used for fasting glucose level and hemoglobin A1c (HbA1c) level.Results: Two hundred sixty-two women (0.89%) in the sample were diagnosed with cervical cancer. Domestic secondhand smoke exposure, diabetes, high fasting glucose level, and high HbA1c significantly increased cervical cancer risk. The respective odd ratios and 95% confidence intervals were: 1.488 (1.002–2.207), 2.369 (1.713–3.274), 1.008 (1.005–1.009), and 1.304 (1.193–1.425). Weekly work hours and work schedule were not significantly related to cervical cancer incidence.Conclusion: Among Korean women, passive exposure to cigarette smoke at home, diabetes, elevated fasting glucose level, and high HbA1c level all increase risk for cervical cancer.

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Secondhand smoke exposure, diabetes, and high BMI are risk factors for uterine cervical cancer: a cross-sectional study from the Korea national health and nutrition examination survey (2010–2018)

BMC Cancer ◽

10.1186/s12885-021-08580-3 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Ji Young Kim ◽

Dae Woo Lee ◽

Min Jeong Kim ◽

Jae Eun Shin ◽

Yeun Joo Shin ◽

...

Keyword(s):

Risk Factors ◽

Cervical Cancer ◽

Secondhand Smoke ◽

Cross Sectional Study ◽

Smoke Exposure ◽

Secondhand Smoke Exposure ◽

Work Schedule ◽

Cross Sectional ◽

Health And Nutrition ◽

High Bmi

Abstract Background Human papilloma virus infection and tobacco smoking are the major risk factors for cervical cancer. There are limited studies searching other risk factors for cervical cancer and the results are not consistent. This study investigated the relations between cervical cancer and possible risk factors, including secondhand cigarette smoke exposure, diabetes, body mass index (BMI), and work schedule. Methods In this cross-sectional study, 29,557 women completed a cervical cancer questionnaire and were selected using 2010–2018 data from the Korea National Health and Nutrition Examination Survey. Details in secondhand smoke exposure, diabetes, BMI, and work schedule were assessed with participants’ health interviews and health-related surveys. Results Two hundred sixty-two women (0.89%) in the sample were diagnosed with cervical cancer. Domestic secondhand smoke exposure, diabetes, and high BMI significantly increased cervical cancer risk. Respective odds ratios and 95% confidence intervals were: 1.547 (1.042–2.297), 2.156 (1.535–3.027), and 1.036 (1.006–1.067). Weekly work hours, and work schedule were not significantly related to cervical cancer incidence. Conclusion Among Korean women, passive exposure to cigarette smoke at home, diabetes, and high BMI increase risk for cervical cancer.

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Abstract T P99: Elevated Fasting Glucose as a Potential Predictor for Asymptomatic Cerebral Stenosis: A Cross-Sectional Study in Chinese Adults

Stroke ◽

10.1161/str.45.suppl_1.tp99 ◽

2014 ◽

Vol 45 (suppl_1) ◽

Author(s):

Jing Wang ◽

Jianwei Wu ◽

Chunxue Wang ◽

Shouling Wu ◽

Xingquan Zhao

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Carotid Stenosis ◽

Glucose Level ◽

Fasting Glucose ◽

Fasting Blood Glucose ◽

Cross Sectional Study ◽

Fasting Glucose Level ◽

Cross Sectional ◽

Potential Risk Factors

Purpose: Cerebral Stenosis is known as an important cause of stroke, and elevated fasting glucose level is traditionally supposed as a risk factor for stroke; however, it is doubtful whether elevated fasting glucose is associated with cerebral stenosis, especially with asymptomatic cerebral stenosis . Methods: 5,309 participants with age of 40 years or older, free of stroke, transient ischemic attack, and coronary disease, were enrolled in this study from 2010 to 2011. Information of potential risk factors for cardiovascular disease were collected and cerebral stenosis was assessed by Doppler ultrasound. Participants were classified into four subtypes: non-cerebral steosis (NCS), intracranial artery stenosis (ICAS), extracranial carotid stenosis (ECCS) and combined intracranial and extracranial carotid stenosis (IECS). Fasting blood glucose (FBG) was also stratified into normal fasting glucose (FBG<5.60mmol/L), impaired fasting glucose (IFG) (FBG: 5.60-6.99mmol/L) and diabetes (FBG>6.99mmol/L) groups. The IFG group was further divided into IFG1 and IFG2 at cutpoint of 6.10mmol/L. A multivariate logistic regression was used to examine the association between FBG and cerebral stenosis. Results: FBG levels were significantly higher in ICAS and IECS groups than the other two groups. In multiple regression analysis, IFG2 level was the risk factor for ICAS (OR 1.50, 95%CI 1.10-2.06), and diabetes level was a powerful predictor for ICAS (OR 1.82, 95%CI 1.43-2.31) and IECS (OR 2.22, 95%CI 1.36-3.62). However, the paper finds fasting glucose level was not a risk factors for ECCS. Conclusions: The results suggest that elevated fasting glucose level is associated with asymptomatic cerebral stenosis, especially with ICAS and IECS, which suggesting the importance of fasting glucose control in the prevention of asymptomatic cerebral stenosis.

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Cardiovascular disease risk factors of ultra-Orthodox Jewish women in Israel: a comparison study

European Journal of Public Health ◽

10.1093/eurpub/ckaa166.735 ◽

2020 ◽

Vol 30 (Supplement_5) ◽

Author(s):

E Leiter ◽

K L Greenberg ◽

M Donchin ◽

O Keidar ◽

S Siemiatycki ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Disease ◽

General Population ◽

Secondhand Smoke ◽

Smoke Exposure ◽

Orthodox Jewish ◽

Minority Population ◽

Secondhand Smoke Exposure ◽

Community Based ◽

Increased Risk

Abstract Background Women from low socio-economic, culturally insular populations are at increased risk for cardiovascular disease (CVD). The ultra-Orthodox Jewish (UOJ) community in Israel is a difficult to access, rapidly growing low socio-economic, insular minority with numerous obstacles to health. The current study investigates CVD-related risk factors (RF) in a sample of OUJ women, comparing sample characteristics with the general population. Addressing the questions, 'Are UOJ women at increased risk for CVD?', 'Which RFs should be addressed beyond the general population's?', this study can inform public health initiatives (PHI) for this and similar populations. Methods Self-administered questionnaires completed by a cluster randomized sample of 239 women from a UOJ community included demographics, fruit, vegetables, and sweetened drink consumption, secondhand smoke exposure, physical activity (PA) engagement, and BMI. Population statistics utilized for comparison of demographic and cardiovascular risk factors were obtained from government-sponsored national surveys. Results Compared with the general population, UOJ women were less likely to consume 5 fruits and vegetables a day (12.7% vs. 24.3%, p<.001) and more likely to consume > 5 cups of sweetened beverages a day (18.6% vs. 12.6%, p=.019). UOJ women also reported less secondhand smoke exposure (7.2% vs. 51.4%, p<.001) and higher rates of PA recommendation adherence (60.1% vs. 25.6%, p<.0001) than the general population. Obesity was higher in UOJ women (24.3% vs. 16.1%, p<.0001). Conclusions This study suggests that PHIs in this population target healthy weight maintenance, nutrition, and PA. As a consequence of this study, the first CVD prevention intervention has been implemented in this population, targeting the identified RFs. Utilizing a mixed methods and community-based participatory approach, this innovative 3-year intervention reached over 2,000 individuals. Key messages This study identified nutrition risk behaviors and high levels of obesity in a difficult to access, minority population. This study informed the planning and implementation of a community-based PHI.

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