Pattern of Thalassemia and Hemoglobinopathies Among Anemic Under-Five Children of Northern Bangladesh: A Hospital Based Cross Sectional Study

2021 ◽  
Author(s):  
Md. Abdur Rafi ◽  
M. Morsed Zaman ◽  
Md. Golam Hossain
Keyword(s):  
Cross Sectional Study ◽  
Severe Form ◽  
Health Concern ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hemoglobin E ◽  
Under Five ◽  
Under Five Children ◽  
Thalassemia Minor ◽  
Different Types

Abstract Background Congenital hemoglobin defects are significant global health concern affecting more than 330,000 newborns every year. In Bangladesh more than half of the under-five children are anemic, but the contribution of hemoglobin disorders to childhood anemia is quite unexplored. Hence, the objective of the present study was to investigate the prevalence and pattern of hemoglobinopathies among anemic under-five (age 6–59 months) children visiting the hematology department of Rajshahi Medical College Hospital (RMCH). Methods This was a retrospective cross-sectional study among anemic patients aged between 6 to 59 months conducted in the hematology department of RMCH from July 2018 to June 2020. The guideline of WHO was used to define the severity of anemia. Hemoglobinopathies was measured using standard methods. Chi-square test was used to find the association between two categorical factors. Results Female and younger children included in the study were more likely to suffer from moderate to severe form of anemia compared to their counterparts. Out of 534 patients 183 were suffering from different types of hemoglobinopathies (prevalence 34.3%). E-β-Thalassemia was the most common type of hemoglobinopathy (14%) followed by Hemoglobin E trait (11%) and β-Thalassemia minor (5.6%). Prevalence of these hemoglobin disorders was comparatively higher among female and older children (p < 0.05). Patients with E-β-Thalassemia and β-Thalassemia major of our study were mostly suffering from severe form of anemia while patients with hemoglobin E trait and β-Thalassemia minor were mostly suffering from mild anemia (p < 0.01). Conclusions A remarkable number of children were suffering from severe anemia and different types of hemoglobinopathies. Gender and age group were the risk factors of anemia and hemoglobinopathies among under-five children. Health authorities of Bangladesh should especially take care of anemic children in this country.

scholarly journals Impact of Community-Led Total Sanitation and Hygiene on Prevalence of Diarrheal Disease and Associated Factors among Under-Five Children: A Comparative Cross-Sectional Study in Selected Woredas of Gamo Gofa Zone, Southern Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Agune Ashole Alto ◽  
Wanzahun Godana ◽  
Genet Gedamu
Keyword(s):  
Drinking Water ◽  
Diarrheal Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children ◽  
Sanitation And Hygiene ◽  
The Impact ◽  
Gamo Gofa

Background. Diarrheal diseases are still one of the major causes of morbidity in under-five children in sub-Saharan Africa. In Ethiopia, diarrhea is responsible for 9% of all deaths and is the major cause of under-five mortality. Objective. To assess the impact of community-led total sanitation and hygiene on the prevalence of diarrheal disease and factors associated among under-five children in Gamo Gofa Zone. Methods. Community-based comparative cross-sectional study design was used to compare the impact of community-led total sanitation and hygiene intervention on under-five diarrheal disease. Multistage sampling method was employed. The data were collected by using pretested structured questionnaires. Data quality was ensured by daily supervision completeness and consistency. The data were coded, entered, and cleaned by using Epi Info version 7 and were analyzed by using SPSS version 20. Bivariate and multivariable analyses were carried out by using binary logistic regression. Significance was declared by using p value of <0.05 and AOR with 95% confidence intervals. Results. The response rate of this study was 93.3%. The overall diarrhea prevalence was 27.5% (CI = (24.06, 30.97)) which was 18.9% (CI = (14.94, 23.2)) in implemented and 36.2%. (CI = (30.41, 41.59)) in nonimplemented woredas. Children whose age was between 12 and 23 months (AOR = 1.6) and greater than 24 months (AOR = 5), availability of handwashing facilities (AOR = 4), disposal of waste in open field (AOR = 9.7), unimproved source of drinking water (AOR = 6.5), using only water for handwashing (AOR = 6), children who started complementary feeding less than 6 months (AOR = 5.6) and greater than 6 months (AOR = 5.2), and utensils used to feed children such as bottle (AOR = 3.9) were the factors positively associated with diarrhea. Conclusion. The overall prevalence of under-five diarrhea was 27.5%. The prevalence was low in CLTSH woredas as compared with non-CLTSH woredas. The study showed that handwashing facility, using only water for handwashing, open refuse disposal, and unimproved source of drinking water among under-five had a statistically significant association with diarrhea occurrence in CLTSH nonimplemented areas. Integrated efforts are needed from the Ministry of Health together with the WASH Project in improving drinking water, handwashing facilities, and solid waste disposal practices.

scholarly journals ASSESSMENT OF NUTRITIONAL STATUS AND ITS DETERMINANTS AMONG CHILDREN IN AGE GROUP OF 1-5 YEARS IN A TRIBAL POPULATION OF COIMBATORE DISTRICT-A CROSS SECTIONAL STUDY

2020 ◽  
pp. 51-54
Author(s):  
T. Pravin ◽  
P.K. Govindarajan ◽  
A. John William Felix
Keyword(s):  
Nutritional Status ◽  
Maternal Education ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children ◽  
Malnourished Children ◽  
Coimbatore District

Background: Under-five children are more vulnerable to malnutrition especially in rural areas resulting in more morbidity and mortality among them. The present study is aimed to assess the prevalence of malnutrition among children of 1-5 years of age in tribal hamlets of Valparai block, Coimbatore district in Tamil Nadu. Methods: A community-based, cross-sectional study was conducted among 95 children in the age group of 1-5 years during December-January 2020. Anthropometric measurements were taken. The indicators of nutritional status of children like stunting, underweight, and wasting were expressed using WHO growth standards. Results: The overall prevalence of malnutrition in our study was 31.6%. Among the 30 (31.6%) malnourished children, 40% were underweight, and 6.67% were severely underweight. 40% were stunted, of which 13.3% were severely stunted. Wasting was present in 23.3% of malnourished children. Severe wasting was not seen. Socio-demographic factors including the type of house, maternal education, BMI of the mother, age of mother at childbirth and place of delivery had significant association with malnutrition among under-five tribal children. Conclusions: Malnutrition poses a serious threat to under-five children. Though many known risk factors of malnutrition have been studied, understanding the local factors linked with malnutrition is so crucial while planning information, education, and communication programs in this area.

scholarly journals Diarrheal Diseases in Under-Five Children and Associated Factors among Farta District Rural Community, Amhara Regional State, North Central Ethiopia: A Comparative Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Yilkal Tafere ◽  
Bedilu Abebe Abate ◽  
Habtamu Demelash Enyew ◽  
Amsalu Belete Mekonnen
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Diarrheal Diseases ◽  
Open Defecation ◽  
Cross Sectional ◽  
North Central ◽  
Central Ethiopia ◽  
Under Five ◽  
Factors Associated ◽  
Under Five Children

Background. Diarrheal diseases are the major cause of morbidity and mortality among under-five children in low- and middle-income countries including Ethiopia. One of the national initiatives to reduce its burden is an implementation of an open-defecation-free program. However, information related to the comparison of diarrheal diseases among residents in open-defecation-free and non-open-defecation-free. Hence, this study assessed the magnitude of diarrheal diseases among residents in open-defecation-free and non-open-defecation-free areas of Farta District, North Central Ethiopia. Methods. A community-based comparative cross-sectional study was conducted among 758 households (378 in open-defecation-free and 380 in non-open-defecation-free kebeles) who have under-five children using a structured questionnaire. A systematic sampling technique was used to select study participants. Binary logistic regression was used to analyze factors associated with diarrheal diseases in the district. Results. Overall, 29.9% of children had diarrheal diseases in the last two weeks prior to the study. The magnitude of diarrheal diseases among under-five children living in open-defecation-free and non-open-defecation-free residents was 19.3% and 40.5%, respectively. Lack of functional handwashing facilities (AOR: 11, 95% CI (8.1–29.6)), improper excreta disposal (AOR: 3.84, 95% CI (2.15–5.65)), and residing in non-open-defecation-free areas (AOR: 2.4, 95% CI (1.72–3.23)) were factors associated with diarrheal diseases. Conclusions. The prevalence of diarrhea among children residing in open-defecation-free areas was lower than that among children those who resided in non-open-defecation-free areas. Lack of functional handwashing facilities, residing in non-open-defecation-free areas, and improper excreta disposal were significantly associated with diarrheal diseases in the district. Strengthening health promotion on non-open defecation, maintaining functional handwashing facilities, and preparing additional handwashing facilities are necessary. Continuous engagement of the community health extension workers is recommended, sustaining the implementation of open-defecation-free programs in the district.

Parent induced self-medication among under five children: an observational cross sectional study

2015 ◽  
Vol 14 (2) ◽  
pp. 81 ◽  
Author(s):  
Saima Nazir ◽  
Kanu Goel ◽  
Anshu Mittal ◽  
Jagjeet Singh ◽  
RKD Goel ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Self Medication ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children

scholarly journals Prevalence and associated factors of diarrhea among under-five children in Debre Berhan Town, Ethiopia 2018: A cross sectional study

2019 ◽  
Author(s):  
Sisay Shine ◽  
Sindew Muhamud ◽  
Solomon Adnew ◽  
Alebachew Demelash
Keyword(s):  
Associated Factors ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Major Public Health Problem ◽  
Sectional Study ◽  
Rota Virus ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children ◽  
Debre Berhan

Abstract Introduction Diarrhea is responsible for 525,000 under five children deaths and 1.7 billion cases in the world and the second leading cause of death among under-five children. It is the major public health problem in developing countries like Ethiopia. The main aim of this study was to assess the prevalence and associated factors of diarrhea among under-five children in Debre Berhan Town, Ethiopia.Methods Community based cross-sectional study design was done among 420 children in Debre Behan Town. Multi-stage sampling technique was used to select the study participants. Data were collected by using pre-tested and structured questionnaire. Odds ratios with 95% confidence intervals were used to assess level of significance.Results The two week prevalence of diarrhea among under-five children was 16.4%. Age of children with 7-11 month years old (AOR: 4.2, 95%CI: 1.2 – 15.3), being the second children (AOR: 3.9, 95%CI: 1.8 – 8.5), not vaccinated against Rota virus (AOR: 10.3, 95%CI: 3.2 – 91.3) and feeding children by using hand (AOR: 2.5, 95%CI: 1.1 - 6.1) were significant predictors of under five children diarrhea.Conclusions This study revealed that the two weeks’ period prevalence of under-five diarrhea was relatively high. Age of children, vaccination against Rota virus and feeding children by using hand were associated with under-five children diarrhea. Education program on the important of vaccination against Rota virus and critical point of hand washing is recommended.

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