scholarly journals Clinical Profile of Migraine Headache Patients: A Descriptive Study of A Single Tertiary Centre in Malaysia

Author(s):  
YUE HUI LAU ◽  
Jessica Kurien ◽  
KENG MING LAU ◽  
Sufian Adenan

Abstract Background:Migraine is one of the most common disabling neurological disorder among adult population in Malaysia. Purpose:To evaluate demographic characteristics among the migraine patients.Methods:A total of 73 patients with the complain of headache, who aged 18 to 65 were recruited prospectively at neurology clinic from December 2017 to April 2019 in Kuala Lumpur Hospital. All new patients were mainly referred by primary care clinics. Demographic characteristics such as age and gender, age of onset, clinical phenotypes, trigger factors, rescue therapy, prophylaxis usage, frequency of headache, psychiatric symptoms, marital status and education level were all evaluated. Migraine headaches were coded according to ICHD-III criteria. Statistical analysis was analysed using SPSS software. Descriptive statistics, mean and standard deviation were used to evaluate for clinical data.Results:44 out of 73 patients had migraine (60.3%). The mean age of migraine patients was 30 and mean age of onset was 24.8. Majority of the sample were female (36, 81.8%), single (23.52.3%) and with tertiary education level (31, 70.5%). The most frequent symptoms included unilateral headache (36, 81.8%) with throbbing in quality (39, 88.6%). The main trigger factor was stress (23, 52.3%). The most frequently used rescue therapies are sleeping and paracetamol ingestion (18, 40.9%). Most of the patients experienced acute attack 4-14 days in a month (15, 34.1%). 42(95.5%) patients were prophylaxis naïve.ConclusionCharacteristics of the migraine patients in Kuala Lumpur Hospital are comparable with previous studies. A registry of headache patients is crucial to determine the prevalence and local impact of the disease in Malaysia.

2021 ◽  
Author(s):  
Yue Hui Lau ◽  
Jessica K Kurien ◽  
Keng Ming Lau ◽  
Sufian Adenan

Abstract Background:Migraine is one of the most common disabling neurological disorder among adult population in Malaysia. Purpose:To evaluate demographic characteristics among the migraine patients.Methods:A total of 73 patients with the complain of headache, who aged 18 to 65 were recruited prospectively at neurology clinic from December 2017 to April 2019 in Kuala Lumpur Hospital. All new patients were mainly referred by primary care clinics. Demographic characteristics such as age and gender, age of onset, clinical phenotypes, trigger factors, rescue therapy, prophylaxis usage, frequency of headache, psychiatric symptoms, marital status and education level were all evaluated. Migraine headaches were coded according to ICHD-III criteria. Statistical analysis was analysed using SPSS software. Descriptive statistics, mean and standard deviation were used to evaluate for clinical data.Results:44 out of 73 patients had migraine (60.3%). The mean age of migraine patients was 30 and mean age of onset was 24.8. Majority of the sample were female (36, 81.8%), single (23.52.3%) and with tertiary education level (31, 70.5%). The most frequent symptoms included unilateral headache (36, 81.8%) with throbbing in quality (39, 88.6%). The main trigger factor was stress (23, 52.3%). The most frequently used rescue therapies are sleeping and paracetamol ingestion (18, 40.9%). Most of the patients experienced acute attack 4-14 days in a month (15, 34.1%). 42(95.5%) patients were prophylaxis naïve.Conclusion:Characteristics of the migraine patients in Kuala Lumpur Hospital are comparable with previous studies. A registry of headache patients is crucial to determine the prevalence and local impact of the disease in Malaysia.


This paper aims to measure the retirement wealth adequacy among population in Malaysia based on 7743 samples from Household Expenditure and Income Survey (HEIS) 2014. The determinants of retirement wealth adequacy are also examined using the OLS regression. The HEIS2014 contains information on household income and expenditure data, together with socio-economic and demographic characteristics of each household head such as age, education level and occupational group. The retirement wealth adequacy is projected using a wealth-need ratio, which is equal to the projected wealth (or income) accumulated in working years divided by the projected total needs (or consumptions) in retirement years. A wealth-need ratio of equal or larger than one indicates that an individual’s retirement wealth is adequate. Based on life cycle hypothesis which states that retirees should retire with a maintained lifestyle, a 70% replacement ratio is used in this study to project the total consumptions throughout retirement years. We also project the total consumptions by implementing different replacement ratios for different salary classes in Malaysia to take into account heterogeneity of consumptions among households. The results show that all households (or 100%) have wealth-need ratio of one or more if we use 70% replacement ratio. However, the percentage of households who have wealth-need ratio of equal or larger than one reduces to 88% when we use different replacement ratios for different income classes. The results from the wealth-need ratio indicates that the following demographic and socio-economic groups have higher percentage of adequate retirement wealth; age 30-35, single (not married), work in management field, degree education, live in region 4 (Pulau Pinang, Selangor, Kuala Lumpur, Putrajaya), and work in private sectors.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Agung Dwi Laksono ◽  
Ratna Dwi Wulandari ◽  
Mursyidul Ibad ◽  
Ina Kusrini

Abstract Background Even though the Indonesian government have set regulations for maintaining exclusive breastfeeding practices, the coverage remains low. The study aims to analyze the effects of mother’s education level on the coverage of exclusive breastfeeding in Indonesia. Methods This study used data from the 2017 Nutrition Status Monitoring Survey. It covered data of 53,528 children under 5 years old (7–59 months) as the samples. Variables included exclusive breastfeeding status, mother’s education level, mother’s age, marital status, employment status, gender, residence, under five’s age and gender. A binary logistics regression was performed in the final test. Results Mothers who graduated from elementary school were 1.167 times more likely to perform exclusive breastfeeding compared to mothers who never attended schools. Additionally, those who graduated from junior high school had 1.203 times possibilities to give exclusive breastfeeding compared to mothers without educational records. While, mothers who graduated from high school were 1.177 times more likely to perform exclusive breastfeeding compared to those without educational records. Mothers who graduated from tertiary education had 1.203 times more possibilities to perform exclusive breastfeeding compared to mothers who were never enrolled to schools. Other variables also became affecting predictors on exclusive breastfeeding, such as mother’s age, mother’s employment status, child’s age, and residence. Conclusions The mother’s education level positively affects exclusive breastfeeding practice in Indonesia.


2021 ◽  
Vol 11 (5) ◽  
pp. 602
Author(s):  
Eleni Bonti ◽  
Sofia Giannoglou ◽  
Marianthi Georgitsi ◽  
Maria Sofologi ◽  
Georgia-Nektaria Porfyri ◽  
...  

The manifestation of Specific Learning Disorder (SLD) during adulthood is one of the least examined research areas among the relevant literature. Therefore, the adult population with SLD is considered a “rare” and “unique” population of major scientific interest. The aim of the current study was to investigate, describe, and analyze the clinical, academic, and socio-demographic characteristics, and other everyday functioning life-skills of adults with SLD, in an attempt to shed more light on this limited field of research. The overall sample consisted of 318 adults, who were assessed for possible SLD. The diagnostic procedure included self-report records (clinical interview), psychometric/cognitive, and learning assessments. The main finding of the study was that SLD, even during adulthood, continues to affect the individuals’ well-being and functionality in all of their life domains. There is an ongoing struggle of this population to obtain academic qualifications in order to gain vocational rehabilitation, as well as a difficulty to create a family, possibly resulting from their unstable occupational status, their financial insecurity, and the emotional/self-esteem issues they usually encounter, due to their ongoing learning problems. Moreover, the various interpersonal characteristics, the comorbidity issues, and the different developmental backgrounds observed in the clinical, academic, personal, social, and occupational profiles of the participants, highlight the enormous heterogeneity and the continuum that characterizes SLD during adulthood. We conclude that there is an imperative need for further research and the construction of more sufficient tools for the assessment and diagnosis of SLD during adulthood, which will take into account the developmental challenges and milestones in a series of domains, in order to assist this “vulnerable” population with their life struggles.


2005 ◽  
Vol 45 (5) ◽  
pp. 615-616 ◽  
Author(s):  
Marthe Fischera ◽  
Kerstin Anneken ◽  
Stefan Evers

2021 ◽  
Author(s):  
Isabelle Brock ◽  
Nicole Eng ◽  
Anne Maitland

Abstract Mast Cell Activation syndrome (MCAS) is a clinical condition, defined by the combination of 1) typical symptoms, 2) laboratory abnormalities and 3) response to treatment. Patients present with episodic symptoms of aberrant mast cell activation, such as abdominal cramping, asthma, hypotensive episodes, tachycardia, anaphylaxis, unexplained arrhythmias, and neurologic/psychiatric symptoms. Both clonal and nonclonal mast cell activation syndromes have been described, with a greater prevalence of non-clonal MCAS among the pediatric and adult population. Numerous extrinsic triggers of mast cell activation (MCA) are described, but recent reports point to nonatopic triggers, as the predominant, extrinsic stimulants of MCA in the adult population. The etiology of MCAS is unclear, though recent studies point to the disruption of the epithelium by infection, toxic exposures or physical trauma, and perturbation the tight regulation of these innate immune cells, associated to the epithelial borders. Here we describe a geriatric patient with adult onset MCAS, following a significant toxic exposure, scombroid poisoning. We also review the relevant literature regarding MCAS diagnosis and management as well as potential mechanisms for this hypersensitivity syndrome in adults.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
J. Maia

Huntington's Disease (HD) is an inherited autosomal dominant disorder characterized by motor, cognitive and psychiatric symptomatology, being considered a paradigmatic neuropsychiatric disorder that includes all three components of the "Triadic Syndromes": dyskinesia, dementia and depression.Firstly described in 1872 as an "Hereditary Chorea" by George Huntington only in 1993 was its responsible gene identified. A person who inherits the HD gene will sooner or later develop the disease. the age of onset, early signs and rate of disease progression vary greatly from person to person.Neuropsychiatric symptoms are an integral part of HD and have been considered the earliest markers of the disease, presenting sometimes more than 10 years before a formal diagnosis is done. Patients may experience dysphoria, mood swings, agitation, irritability, hostile outbursts, psychotic symptoms and deep bouts of depression with suicidal ideation. Personality change is reported in 48% of the cases, with the paranoid subtype being described as the most prevalent. the clinical case presented illustrates a case of HD which started with insidious psychiatric symptoms and an important personality change.Despite a wide number of medications being prescribed to help control emotional, movement and behaviour problems, there is still no treatment to stop or reverse the course of the disease. Furthermore, psychiatric manifestations are often amenable to treatment, and relief of these symptoms may provide significant improvement in patient's and caregivers quality of life.A greater awarness of psychiatric manifestations of HD is essential to an earlier diagnosis and an optimized therapeutic approach.


2013 ◽  
Vol 59 (6) ◽  
pp. 285-288
Author(s):  
Blesneac Cristina ◽  
Benedek Theodora ◽  
Togănel Rodica ◽  
Benedek I

Abstract Background: Hypertrophic cardiomyopathy, one of the most common inherited cardiomyopathies, is a heterogeneous disease resulting from sarcomeric protein mutations, with an incidence in the adult population of 1:500. Current information on the epidemiology and outcomes of this disease in children is limited. Methods: Thirty-four children diagnosed with hypertrophic cardiomyopathy in the Pediatric Cardiology Department from Tîrgu Mureș were evaluated concerning familial and personal history, clinical, paraclinical and therapeutic aspects. Hypertrophic cardiomyopathy was defined by the presence of a hypertrophied, non-dilated ventricle, in the absence of a cardiac or systemic disease that could produce ventricular hypertrophy. Results: The youngest diagnosed child was a neonate, a total of 10 patients being diagnosed until 1 year of age. In 6 cases a positive familial history was found. Noonan syndrome was found in 2 cases. Only 21 patients were symptomatic, the predominant symptoms being shortness of breath on exertion with exercise limitations. Left ventricular outflow tract obstruction was present in 21 cases (61.7%). Twenty-four patients were on β-blocking therapy, while 4 patients underwent septal myectomy. Conclusions: Hypertrophic cardiomyopathy is a heterogeneous disorder in terms of evolution, age of onset, type and extent of hypertrophy, and the risk of sudden death. It can affect children of any age. There is a need for a complex evaluation, including familial and personal anamnesis, clinical examination, electrocardiogram and echocardiography of all patients. It is highly important to develop screening strategies, including genetic testing, for an early diagnosis, especially in asymptomatic patients with a positive familial background


2002 ◽  
Vol 63 (4) ◽  
pp. 184-191 ◽  
Author(s):  
Dominique Tessier ◽  
Huguette Turgeon O'brien ◽  
John Zee ◽  
Johanne Marin ◽  
Karine Tremblay ◽  
...  

In the last 30 years, the prevalence of low dietary iron intake has increased, partly because North Americans have been encouraged to choose lower fat foods, including leaner meats. As a result, there has been a decrease in red meat consumption. The objective of this study was to estimate absorbable iron intakes of a representative sample of the Quebec adult population and to compare these results with the new North American recommendations for iron. Dietary intakes were obtained by 24-hour recall and absorbable iron intakes were estimated using Monsen & coworker's model. While 18.9 % and 2.5% of women and men respectively had an iron intake below the estimated average requirement (EAR), 66.2 % and 25.6% had an estimated available iron intake below the recommended level for absorbed iron. Beef consumption had the strongest association with estimated absorbable iron, followed by vegetables. Subjects with a high education level consumed significantly less meat, beef and heme iron than subjects whose education level was low or moderate. These results indicate that there is a need for improving iron intake in the Quebec adult population.


2016 ◽  
Vol 6 (6) ◽  
pp. 289-296 ◽  
Author(s):  
Jerry McKee ◽  
Nancy Brahm

Abstract Patients with underlying medical disease can present to the health care system with psychiatric symptoms predominating. Identification of an underlying medical condition masquerading as a psychiatric disorder can be challenging for clinicians, especially in patients with an existing psychiatric condition. The term medical mimic or secondary psychosis has been used to describe this clinical situation. Diagnostic categories from The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, that may encompass medical mimics include substance-induced disorders, which includes medications, and unspecified mental disorder due to another medical condition in situations where the clinician may lack needed information for a complete diagnosis. At this time, there is no single diagnostic test or procedure available to differentiate primary versus secondary psychosis on the basis of psychopathology presentation alone. When considering a diagnosis, clinicians should evaluate for the presence of atypical features uncharacteristic of the psychiatric symptoms observed; this may include changes in functionality and/or age of onset and symptom presentation severity. The purpose of this work is to provide a structured clinical framework for evaluation for medical mimics, identify groups considered to be at highest risk for medical mimics, and present common syndromic features suggestive of a medical mimic. Selected case scenarios are used to illustrate key concepts for evaluating and assessing a patient presenting with acute psychiatric symptomatology to improve judgment in ruling out potential medical causality.


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