Influence of Mercury Exposure During Pregnancy to Neurodevelopmental Disorder: A Systematic Review Protocol

2021 ◽  
Author(s):  
Nhelvy Kumala Nasruddin ◽  
Hasnawati Amqam ◽  
Agus Bintara Wirayuda Wirayuda ◽  
Muh. Fajaruddin Natsir ◽  
Syamsuar Syamsuar
Keyword(s):  
Systematic Review ◽  
Data Extraction ◽  
Mercury Level ◽  
Meta Analysis ◽  
Neurodevelopmental Disorder ◽  
Incidence Rates ◽  
Mercury Exposure ◽  
Postnatal Exposure ◽  
Open Access Journals ◽  
The Relationship

Abstract Background: The general population might expose to Hg through various pathways. Prenatal or postnatal exposure to mercury might affect the fetus's neurodevelopment and then further affect the growth and development of the children. There are many reports on mercury exposure, but systematic reviews to conclude the result are still limited, particularly concerning pregnancy. Previous studies focus on one exposure path to Hg and biomarker. The objective is to systematically summarize the relevant records from systematic studies on the relationship between the exposure pattern during pregnancy to pregnant women's Hg concentration and neurodevelopmental disorder that occurred in the children.Method: We will search online databases (Google Schoolar, PUBMED, Sciencedirect, Proquest, Web of Science, Springerlink, DOAJ (Directory of Open Access Journals) and EBSCO MEDLINE) and reference lists of included articles. Two reviewers will independently screen the titles and abstracts and select the research involving pregnant women with mercury exposure and neurodevelopmental disorder fetus or children. These reviewers will also independently extract and manage the obtained data using a data extraction form that will cover information on characteristic, exposure, and outcomes. Meta-analysis will also be applied when homogeneous group of studies found.Discussion: This study will describe the available epidemiological evidence and summarise prevalence and incidence rates of mercury exposure and neurodevelopmental disorder. Mean difference of mercury level will be also presented. A better understanding of the relationship between mercury exposure and any neurodevelopmental disorder form will be helpful in the development of guidelines for mercury exposure management.Systematic review registration: It has been submitted to PROSPERO on February, 10th 2021.

scholarly journals How effective is teamwork really? The relationship between teamwork and performance in healthcare teams: a systematic review and meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e028280 ◽  
Author(s):  
Jan B. Schmutz ◽  
Laurenz L. Meier ◽  
Tanja Manser
Keyword(s):  
Systematic Review ◽  
Clinical Performance ◽  
Data Extraction ◽  
Meta Analysis ◽  
Random Effect ◽  
Performance Measure ◽  
Task Type ◽  
Eligibility Criteria ◽  
Expert Rating ◽  
The Relationship

ObjectivesTo investigate the relationship between teamwork and clinical performance and potential moderating variables of this relationship.DesignSystematic review and meta-analysis.Data sourcePubMed was searched in June 2018 without a limit on the date of publication. Additional literature was selected through a manual backward search of relevant reviews, manual backward and forward search of studies included in the meta-analysis and contacting of selected authors via email.Eligibility criteriaStudies were included if they reported a relationship between a teamwork process (eg, coordination, non-technical skills) and a performance measure (eg, checklist based expert rating, errors) in an acute care setting.Data extraction and synthesisModerator variables (ie, professional composition, team familiarity, average team size, task type, patient realism and type of performance measure) were coded and random-effect models were estimated. Two investigators independently extracted information on study characteristics in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.ResultsThe review identified 2002 articles of which 31 were included in the meta-analysis comprising 1390 teams. The sample-sized weighted mean correlation wasr=0.28 (corresponding to an OR of 2.8), indicating that teamwork is positively related to performance. The test of moderators was not significant, suggesting that the examined factors did not influence the average effect of teamwork on performance.ConclusionTeamwork has a medium-sized effect on performance. The analysis of moderators illustrated that teamwork relates to performance regardless of characteristics of the team or task. Therefore, healthcare organisations should recognise the value of teamwork and emphasise approaches that maintain and improve teamwork for the benefit of their patients.

scholarly journals Incidence rate and basic reproduction number of Coronavirus diseases (COVID-19): a systematic review and meta-analysis protocol

2020 ◽  
Author(s):  
Hailay Abrha Gesesew ◽  
William Mude ◽  
Tafadzwa Nyanhanda ◽  
Lillian Mwanri
Keyword(s):  
Systematic Review ◽  
Data Extraction ◽  
Meta Analysis ◽  
Quantitative Information ◽  
Incidence Rates ◽  
World Health ◽  
Bibliographic Databases ◽  
Search Term ◽  
Reproduction Numbers ◽  
Health Organization

Abstract Background : World Health Organization declared Coronavirus (COVID-19) as a newly emerging disease on 31 December 2019. In a space of two-months, there have been several studies reporting incidence rates, incubation periods, fatality rates, basic and effective reproduction numbers of the disease. However, the data have not been synthesized and pooled together to determine the global average. Objective : The present study aims to systematically review available global evidence on incidence rates, and basic and effective reproduction numbers of COVID-19. Methods : This is a protocol for a systematic review of available quantitative studies published in English. Studies which describe the incidence rates, and basic and effective reproduction numbers of COVID-19 will be included in the search. Initially, search term concepts will be constructed through a preliminary search on Google scholar. Then, we will perform a full systematic search using the identified concepts in the following electronic bibliographic databases: SCOPUS, PubMed, Web of Sciences and CINAHL. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) will be used to schematically present the full search strategy. Standardised Joanna Briggs Institute (JBI) quality appraisal and selection tools, and data extraction tools will be used to recruit studies and extract data from the included studies, respectively. Thematic analysis will be used to analyse the non-quantifiable data, and meta-analysis will be used to pool the quantitative information.

Preterm Birth and Breast Cancer Risk: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Maryam Razavi ◽  
Mahdi Sepidarkish ◽  
Arezoo Maleki-Hajiagha ◽  
Samira Vesali ◽  
Amir Almasi-Hashiani ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Preterm Birth ◽  
Data Extraction ◽  
Meta Analysis ◽  
Bibliographic Databases ◽  
Publication Date ◽  
More Care ◽  
The Relationship ◽  
Significant Increment

Abstract Background: The characteristics of pregnancy, such as gestational age are related to the level of maternal hormones, which levels of these hormones can be associated with breast cancer (BC) risk. Therefore, the aim of this study was to determine the relationship between the preterm birth (PB) and BC risk in women in a systematic review and meta-analysis.Methods: In this systematic review and meta-analysis, published studies were located back to the earliest available publication date (1983), using the Medline/PubMed, Embase, Scopus and Web of Science (Clarivate analytics) bibliographic databases. Eligibility, methodological quality, and data extraction were done by two independent reviewers, and finally, to calculate the pooled estimates, Meta-analysis was performed.Results: Thirteen studies including a total of 2,845,553 women were included in this meta-analysis. Pooled results suggested that PB could increase the risk of BC (RR= 1.03, 95% CI: 1.00, 1.07; I2= 62.5%). Risk was significantly increased in women with a PB at >37 gestational weeks (RR = 1.03, 95% CI: 1.01, 1.06) and 26-31 gestational weeks (RR = 1.03, 95% CI: 1.01, 1.06) compared to those with 40-41 gestational weeks. A significant increment in the risk of BC in uniparous women with a PB (RR = 1.05, 95% CI = 1.01, 1.08) and women with >45 years (RR = 1.12, 95% CI = 1.01, 1.24) was observed. Conclusions: The results of this study supported the higher risk of BC in all woman with PB, primiparous women and women with >45 years. Therefore, more care and screening for early detection of the disease is recommended in these women.

scholarly journals Association Between Asthma and Migraine: A Systematic Review and Meta-Analysis of Observational Studies

2021 ◽  
Vol 2 ◽  
Author(s):  
Lin-Lin Kang ◽  
Pei-En Chen ◽  
Tao-Hsin Tung ◽  
Ching-Wen Chien
Keyword(s):  
Systematic Review ◽  
Cohort Studies ◽  
Observational Studies ◽  
Data Extraction ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Cross Sectional ◽  
Newcastle Ottawa Scale ◽  
The Cochrane Library ◽  
The Relationship

Objectives: The purpose of this study was to determine the association between asthma and migraine and assess the risk for migraine in patients with asthma.Methods: We systematically searched the Cochrane Library, PubMed, Medical Literature Analysis and Retrieval System Online (MEDLINE), and Excerpta Medica dataBASE (EMBASE) databases from inception to September 26, 2021, for indexed observational studies that examined either the odds or risk of migraine in subjects with asthma. The qualities of the included studies were evaluated using the Newcastle–Ottawa Scale. A random-effects meta-analysis was performed to calculate the odds ratio for case-control and cross-sectional studies and the risk ratio for cohort studies.Results: Seven observational studies (four cross-sectional and three cohort studies) with a total of 549,534 study subjects were included in this systematic review and meta-analysis and selected for data extraction. Four articles were considered to be of moderate quality; other studies were considered to be of high quality. Asthma was associated with increased odds (OR, 1.85; 95%CI, 1.39–2.45) and risk of migraine (RR, 1.70; 95%CI, 1.52–1.90).Conclusions: The available evidence that supports the existence of an association between asthma and migraine is limited. Clinicians should be aware that patients with asthma show both increased prevalence and incidence of migraine. Further studies are warranted to further clarify the relationship between asthma and migraine.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=185881, identifier: CRD42020185881.

A Systematic Review and a Meta-Analysis of the Relationship Between Problem Finding and Creativity

2017 ◽  
Author(s):  
Ahmed M. Abdulla ◽  
Sue Hyeon Paek ◽  
Rodney Dishman ◽  
Bonnie Cramond ◽  
Mark A. Runco
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Problem Finding ◽  
The Relationship

A Meta Analytic Review of the Relationship between Emotional Intelligence and Leadership Effectiveness

2019 ◽  
Vol 118 (9) ◽  
pp. 118-126
Author(s):  
Augusty P. A ◽  
Jain Mathew
Keyword(s):  
Systematic Review ◽  
Emotional Intelligence ◽  
Direct Relationship ◽  
Effective Leadership ◽  
Leadership Effectiveness ◽  
Meta Analysis ◽  
Correlation Coefficients ◽  
Review Of Literature ◽  
Analytic Review ◽  
The Relationship

The study evaluates the relationship between Emotional Intelligence and Leadership Effectiveness through a Systematic Review of Literature. The relationship has been evaluated in two steps. First, a Systematic review of literature was done to provide a theoretical framework to link the dimensions of Emotional Intelligence to the elements of effective leadership. Meta-analysis was then used to consolidate empirical evidence of the relationship. The studies for the meta-analysis were sourced from Pro Quest and EBSCO and the correlation coefficients of the studies were analysed. Only articles that presented the direct relationship between the variables were included in the study. The results of the analysis revealed a strong, statistically significant relationship between emotional intelligence and effective leadership. The findings of the study provide evidence for the proposition that Emotional Intelligence and Leadership Effectiveness are interrelated.

Systematic review and meta-analysis of Altruistic and Game-playing Love

2020 ◽  
Author(s):  
Hossein Dabiriyan Tehrani ◽  
Sara Yamini
Keyword(s):  
Systematic Review ◽  
Subgroup Analysis ◽  
Meta Analysis ◽  
Game Playing ◽  
Love Styles ◽  
Collectivistic Culture ◽  
Meta Regression ◽  
Collectivistic Cultures ◽  
The Relationship

This systematic review aimed to find attitudes toward Altruistic and Game-playing love styles across individualistic and collectivistic cultures. Addressing major moderators concerning Altruistic and Game-playing love styles are the secondary objectives of this review. This review included 102 articles comprising samples from 37 countries (N = 41997). The findings of this meta-analysis show that there is a collectivistic and individualistic difference in Game-playing but not in the Altruistic love style. Collectivistic and individualistic cultures, on average, demonstrate the same perception concerning the Altruistic love style, whereas collectivistic culture shows the Game-playing love style more strongly. To explain the role of moderators in key measures, the subgroup analysis and meta-regression show that both Game-playing and Altruistic love styles decline by increasing the length of the relationship. Likewise, having children affects these love styles such that the Altruistic love style is improved, and the Game-playing love style is reduced by the presence of children in families.

scholarly journals Misuse of medication in adult substance misuse services: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e047283
Author(s):  
Rosalind Gittins ◽  
Louise Missen ◽  
Ian Maidment
Keyword(s):  
Systematic Review ◽  
Substance Misuse ◽  
Data Extraction ◽  
Meta Analysis ◽  
Grey Literature ◽  
Opioid Analgesics ◽  
Physical And Mental Health ◽  
Qualitative Synthesis ◽  
Treatment Services ◽  
The Impact

IntroductionThere is a growing concern about the misuse of over the counter (OTC) and prescription only medication (POM) because of the impact on physical and mental health, drug interactions, overdoses and drug-related deaths. These medicines include opioid analgesics, anxiolytics such as pregabalin and diazepam and antidepressants. This protocol outlines how a systematic review will be undertaken (during June 2021), which aims to examine the literature on the pattern of OTC and POM misuse among adults who are accessing substance misuse treatment services. It will include the types of medication being taken, prevalence and demographic characteristics of people who access treatment services.Methods and analysisAn electronic search will be conducted on the Cochrane, OVID Medline, Pubmed, Scopus and Web of Science databases as well as grey literature. Two independent reviewers will conduct the initial title and abstract screenings, using predetermined criteria for inclusion and exclusion. If selected for inclusion, full-text data extraction will be conducted using a pilot-tested data extraction form. A third reviewer will resolve disagreements if consensus cannot be reached. Quality and risk of bias assessment will be conducted for all included studies. A qualitative synthesis and summary of the data will be provided. If possible, a meta-analysis with heterogeneity calculation will be conducted; otherwise, Synthesis Without Meta-analysis will be undertaken for quantitative data. The reporting of this protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Ethics and disseminationEthical approval is not required. Findings will be peer reviewed, published and shared verbally, electronically and in print, with interested clinicians and policymakers.PROSPERO registration numberCRD42020135216.

scholarly journals Prevalence of retinopathy in prediabetes: protocol for a systematic review and meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e040997
Author(s):  
Varo Kirthi ◽  
Paul Nderitu ◽  
Uazman Alam ◽  
Jennifer Evans ◽  
Sarah Nevitt ◽  
...  
Keyword(s):  
Systematic Review ◽  
Diabetic Retinopathy ◽  
Data Extraction ◽  
Meta Analysis ◽  
International Diabetes Federation ◽  
Current Data ◽  
Risk Of Bias ◽  
Fundus Photography ◽  
Primary Data ◽  
Cochrane Library

IntroductionThere is growing evidence of a higher than expected prevalence of retinopathy in prediabetes. This paper presents the protocol of a systematic review and meta-analysis of retinopathy in prediabetes. The aim of the review is to estimate the prevalence of retinopathy in prediabetes and to summarise the current data.Methods and analysisThis protocol is developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) guidelines. A comprehensive electronic bibliographic search will be conducted in MEDLINE, EMBASE, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Google Scholar and the Cochrane Library. Eligible studies will report prevalence data for retinopathy on fundus photography in adults with prediabetes. No time restrictions will be placed on the date of publication. Screening for eligible studies and data extraction will be conducted by two reviewers independently, using predefined inclusion criteria and prepiloted data extraction forms. Disagreements between the reviewers will be resolved by discussion, and if required, a third (senior) reviewer will arbitrate.The primary outcome is the prevalence of any standard features of diabetic retinopathy (DR) on fundus photography, as per International Clinical Diabetic Retinopathy Severity Scale (ICDRSS) classification. Secondary outcomes are the prevalence of (1) any retinal microvascular abnormalities on fundus photography that are not standard features of DR as per ICDRSS classification and (2) any macular microvascular abnormalities on fundus photography, including but not limited to the presence of macular exudates, microaneurysms and haemorrhages. Risk of bias for included studies will be assessed using a validated risk of bias tool for prevalence studies. Pooled estimates for the prespecified outcomes of interest will be calculated using random effects meta-analytic techniques. Heterogeneity will be assessed using the I2 statistic.Ethics and disseminationEthical approval is not required as this is a protocol for a systematic review and no primary data are to be collected. Findings will be disseminated through peer-reviewed publications and presentations at national and international meetings including Diabetes UK, European Association for the Study of Diabetes, American Diabetes Association and International Diabetes Federation conferences.PROSPERO registration numberCRD42020184820.

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