Comparison of Clinical Characteristics of Adolescent Women With Different Subtypes of Anorexia Nervosa With First Episode and Without Treatment

2021 ◽  
Author(s):  
renyun zhang ◽  
limin yang ◽  
defeng xu ◽  
haibo ma
Keyword(s):  
Anorexia Nervosa ◽  
Blood Cells ◽  
Clinical Characteristics ◽  
White Blood Cells ◽  
Multiple Organ ◽  
First Episode ◽  
Healthy Controls ◽  
Adolescent Women ◽  
Peripheral White Blood Cells ◽  
Organ Complications

Abstract Background This study compared whether differences between different anorexia nervosa(AN)subtypes(R-AN,B-AN) in multiple organ complications. Methods Peripheral white blood cells (WBCs),thyroid function,etc, were measured in 53 patients (R-AN = 30,B-AN = 23)and compared 55 healthy controls (HCs) Results Compared with HCs, significant differences between R-AN in T, P, DBP, SBP WBC, PRL, TT4, TSH, FT3, FT4, TT3, TP, HGB, RBC,, EDI total score and DT, I, ID, IA ,BD, P and MF. Compared with HCs, significant differences between B-AN in DBP, WBC, PRL, TT4, FT3, FT4, TT3, TP, HGB, RBC,, EDI total score, DT, BD, I, ID, and IA and differences in PLT and P. significant differences between R-AN and B-AN in T, P, DBP, SBP, PRL, TSH, B, FT4, and HGB. In R-AN, BMI negatively correlated with amenorrhea, and PRL EDI total score, DT, BD, and P positively correlated with DBP, SBP, HGB and GLB. In B-AN, BMI negatively correlated with amenorrhea, PRL, EDI total score, and DT, and B, BD, positively correlated with T and DBP. Conclusion The effects of R-AN and B-AN on T, P, DBP, SBP, PRL TSH, B, FT4, and HGB were different, and BMI played a role in the changes.

Laparoscopic sleeve gastrectomy induces molecular changes in peripheral white blood cells

2020 ◽  
Vol 39 (2) ◽  
pp. 592-598
Author(s):  
Marc Beisani ◽  
Stella Pappa ◽  
Pau Moreno ◽  
Eva Martínez ◽  
Jordi Tarascó ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Blood Cells ◽  
White Blood Cells ◽  
Molecular Changes ◽  
Peripheral White Blood Cells

scholarly journals Gene expression of the heat stress response in bovine peripheral white blood cells and milk somatic cells in vivo

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
J. B. Garner ◽  
A. J. Chamberlain ◽  
C. Vander Jagt ◽  
T. T. T. Nguyen ◽  
B. A. Mason ◽  
...  
Keyword(s):  
Gene Expression ◽  
Heat Stress ◽  
Blood Cells ◽  
White Blood Cells ◽  
Somatic Cells ◽  
Holstein Friesian ◽  
Milk Somatic Cells ◽  
Peripheral White Blood Cells ◽  
Friesian Cows

Abstract Heat stress in dairy cattle leads to reduction in feed intake and milk production as well as the induction of many physiological stress responses. The genes implicated in the response to heat stress in vivo are not well characterised. With the aim of identifying such genes, an experiment was conducted to perform differential gene expression in peripheral white blood cells and milk somatic cells in vivo in 6 Holstein Friesian cows in thermoneutral conditions and in 6 Holstein Friesian cows exposed to a short-term moderate heat challenge. RNA sequences from peripheral white blood cells and milk somatic cells were used to quantify full transcriptome gene expression. Genes commonly differentially expressed (DE) in both the peripheral white blood cells and in milk somatic cells were associated with the cellular stress response, apoptosis, oxidative stress and glucose metabolism. Genes DE in peripheral white blood cells of cows exposed to the heat challenge compared to the thermoneutral control were related to inflammation, lipid metabolism, carbohydrate metabolism and the cardiovascular system. Genes DE in milk somatic cells compared to the thermoneutral control were involved in the response to stress, thermoregulation and vasodilation. These findings provide new insights into the cellular adaptations induced during the response to short term moderate heat stress in dairy cattle and identify potential candidate genes (BDKRB1 and SNORA19) for future research.

The blood cells and blood count

2016 ◽  
Author(s):  
Tyler J. Albert ◽  
Erik R. Swenson
Keyword(s):  
Stem Cell ◽  
Blood Cells ◽  
White Blood Cells ◽  
Peripheral Blood Smear ◽  
Cell Types ◽  
Multiple Organ ◽  
Carbon Dioxide Transport ◽  
Vascular Integrity ◽  
Hematopoietic Stem ◽  
Critical Components

Blood is a dynamic fluid consisting of cellular and plasma components undergoing constant regeneration and recycling. Like most physiological systems, the concentrations of these components are tightly regulated within narrow limits under normal conditions. In the critically-ill population, however, haematological abnormalities frequently occur and are largely due to non-haematological single- or multiple-organ pathology. Haematopoiesis originates from the pluripotent stem cell, which undergoes replication, proliferation, and differentiation, giving rise to cells of the erythroid, myeloid, and lymphoid series, as well as megakaryocytes, the precursors to platelets. The haemostatic system is responsible for maintaining blood fluidity and, at the same time, prevents blood loss by initiating rapid, localized, and appropriate blood clotting at sites of vascular damage. This system is complex, comprising both cellular and plasma elements, i.e. platelets, coagulation and fibrinolytic cascades, the natural intrinsic and extrinsic pathways of anticoagulation, and the vascular endothelium. A rapid, reliable, and inexpensive method of examining haematological disorders is the peripheral blood smear, which allows practitioners to assess the functional status of the bone marrow during cytopenic states. Red blood cells, which are primarily concerned with oxygen and carbon dioxide transport, have a normal lifespan of only 120 days and require constant erythropoiesis. White blood cells represent a summation of several circulating cell types, each deriving from the hematopoietic stem cell, together forming the critical components of both the innate and adaptive immune systems. Platelets are integral to haemostasis, and also aid our inflammatory and immune responses, help maintain vascular integrity, and contribute to wound healing.

Sign in / Sign up

Export Citation Format

Share Document