scholarly journals Cerebrospinal Fluid Analysis Predicts Enhancement on MRI in Bacterial and Tuberculous Meningitis: A Retrospective Observational Study

2021 ◽  
Author(s):  
Ryoji Goto ◽  
Yurino Horiuchi ◽  
Haruka Kawakami ◽  
Ayaka Chikada ◽  
Tsutomu Yasuda ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Tuberculous Meningitis ◽  
Mri Findings ◽  
Fluid Analysis ◽  
Csf Analysis ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Discriminant Ability ◽  
Mri Scans ◽  
Contrast Enhanced Mri

Abstract Background Along with cerebrospinal fluid (CSF) analysis, enhancement on contrast-enhanced MRI scans are useful to diagnose and presume the pathogen of meningitis. However, the conditions for its appearance have not been clarified. This study aimed to investigate the possibility of CSF parameters as predictors of the existence of enhancement on contrast-enhanced head or spinal MRI scans in patients with bacterial meningitis (BM) or tuberculous meningitis (TM).Methods A total of 12 patients with BM and 23 patients with TM who underwent both CSF analyses and contrast-enhanced MRI scans were included in this study. The correlation between CSF analyses and MRI findings has been examined using receiver operating characteristic (ROC) analysis.Results Contrast enhancement was found in 7 and 10 patients with BM and TM, respectively. In patients with BM, higher CSF protein and lower CSF glucose were associated with the presence of the enhancement on MRI, while the CSF leukocyte or neutrocyte count did not show any difference. In contrast, not only the CSF protein and glucose but also the leukocyte and lymphocyte counts were associated with the enhancement in patients with TM. Furthermore, CSF adenosine deaminase (ADA) in patients with TM showed neither correlation with CSF leukocyte count nor discriminant ability of the MRI findings.Conclusions CSF analysis predicts the existence of enhancement on contrast-enhanced MRI scans of the central nervous system both in patients with BM and those with TM. Our findings about the CSF cell count and CSF ADA indicate the mechanism of the blood–brain barrier (BBB) breakdown in BM and TM.

Serial MRI and CSF Analysis in a Dog Treated with Intrathecal Amphotericin B for Protothecosis

2012 ◽  
Vol 48 (2) ◽  
pp. 125-131 ◽  
Author(s):  
Martin Young ◽  
William Bush ◽  
Melissa Sanchez ◽  
Pat Gavin ◽  
Mathew Williams
Keyword(s):  
Cerebrospinal Fluid ◽  
Amphotericin B ◽  
Head Tilt ◽  
Mri Findings ◽  
Lipid Complex ◽  
Fluid Analysis ◽  
Csf Analysis ◽  
Transient Improvement ◽  
The Right ◽  
The Brain

A 3 yr old female spayed English setter mixed-breed dog presented with diarrhea, weight loss, side stepping to the right, and a right head tilt. Rectal and cerebrospinal fluid cytology and culture confirmed a diagnosis of Prototheca zopfii. MRI of the brain showed inflammation of the brain and meninges, ventriculomegaly, and syringomyelia. Treatment with prednisone, itraconazole, and amphotericin B lipid complex administered intrathecally yielded transient improvement. Progressive brainstem signs were noted, and a repeat MRI and cerebrospinal fluid analysis documented persistent disease. This is the first description of the MRI findings and treatment with intrathecal amphoteracin B lipid complex for protothecosis of the central nervous system. Protothecosis should be considered in dogs with chronic diarrhea and compatible MRI findings.

scholarly journals Contrast-enhanced MRI findings of the knee in healthy children; establishing normal values

2017 ◽  
Vol 28 (3) ◽  
pp. 1167-1174 ◽  
Author(s):  
Robert Hemke ◽  
J. Merlijn van den Berg ◽  
Charlotte M. Nusman ◽  
E. Charlotte van Gulik ◽  
Anouk M. Barendregt ◽  
...  
Keyword(s):  
Normal Values ◽  
Healthy Children ◽  
Mri Findings ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

Gadolinium-enhanced preoperative MRI scans as a prognostic parameter in scaphoid nonunion

2010 ◽  
Vol 36 (1) ◽  
pp. 23-28 ◽  
Author(s):  
K. Megerle ◽  
H. Worg ◽  
G. Christopoulos ◽  
R. Schmitt ◽  
H. Krimmer
Keyword(s):  
Screw Fixation ◽  
Proximal Fragment ◽  
Scaphoid Nonunion ◽  
Mri Scan ◽  
Intraoperative Bleeding ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Mri Scans ◽  
Scaphoid Reconstruction ◽  
Contrast Enhanced Mri

The purpose of this prospective study was to correlate preoperative gadolinium-enhanced MRI scans with intraoperative bleeding of the proximal fragment and postoperative union in a series of consecutive patients with established scaphoid nonunions. In 60 patients (6 females, 54 males) with a mean age of 29 years, scaphoid perfusion was judged preoperatively as normal, impaired or absent using a gadolinium-enhanced MRI scan. Scaphoid reconstruction was performed using a nonvascularized bone graft and screw fixation. Perfusion of the proximal fragment was assessed intraoperatively in 49 of 60 patients; compromised or absent vascularity was predicted with a specificity of 90% by contrast-enhanced MRI. However, there was no significant correlation between preoperative MRI assessment of vascularity and subsequent union of the scaphoid.

Contrast Enhanced MRI Findings of Ductal Carcinoma in Situ

2006 ◽  
Vol 55 (2) ◽  
pp. 191
Author(s):  
Bong Joo Kang ◽  
Eun Suk Cha ◽  
Hyeon Sook Kim ◽  
Young Jin Shu ◽  
Hyun Joo Choi
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Mri Findings ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

scholarly journals Exploring contrast-enhanced MRI findings of the clinically non-inflamed symptomatic pediatric wrist

2020 ◽  
Vol 50 (10) ◽  
pp. 1387-1396
Author(s):  
Floris Verkuil ◽  
E. Charlotte van Gulik ◽  
Charlotte M. Nusman ◽  
Anouk M. Barendregt ◽  
Amara Nassar-Sheikh Rashid ◽  
...  
Keyword(s):  
Mri Findings ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

scholarly journals Magnetic resonance imaging findings in 11 cases of dedifferentiated endometrial carcinoma of the uterus

2021 ◽  
Author(s):  
Nao Kikkawa ◽  
Kimiteru Ito ◽  
Hiroshi Yoshida ◽  
Mayumi Kobayashi Kato ◽  
Yuko Kubo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Endometrial Carcinoma ◽  
Low Grade ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Intratumoral Hemorrhage ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

Abstract Purpose We evaluated magnetic resonance imaging (MRI) findings of dedifferentiated endometrial carcinoma (DEC), comprising undifferentiated carcinoma and low-grade endometrioid carcinoma. Materials and methods We recruited 11 patients with pathologically proven DEC treated at our institute. We evaluated primary lesion size, location and signal intensity on MRI, and prognosis. MRI and pathological findings were compared in eight resected patients. Results Primary tumors ranged from 16 to 206 mm in diameter. DEC was located at the endometrium in 9 of the 11 patients; the remaining two patients showed diffuse involvement of the enlarged myometrium. These two patients with diffuse involvement type died within 4 months. Of the eight patients who underwent resection, seven had macroscopic intratumoral hemorrhage and six showed a high signal on T1-weighted images or low signal on T2-weighted images. Of the eight resected patients, four had tumor necrosis > 25% and tumor size > 5 cm. In these patients, necrosis appeared as nonenhanced areas on contrast-enhanced MRI. Conclusion MRI findings of DEC showed two patterns: mass-forming type and diffuse myometrial type with poor prognosis. Most patients with DEC had intratumoral hemorrhage, and large tumors (> 5 cm) had gross necrosis, which appeared as nonenhanced areas on contrast-enhanced MRI.

scholarly journals Comparison of contrast-enhanced MRI features of the (teno)synovium in the wrist of patients with juvenile idiopathic arthritis and pediatric controls

2021 ◽  
Author(s):  
Jeffrey M. A. van der Krogt ◽  
F. Verkuil ◽  
E. Charlotte van Gulik ◽  
Robert Hemke ◽  
J. Merlijn van den Berg ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Clinical Signs ◽  
Joint Inflammation ◽  
Enhanced Mri ◽  
Mri Features ◽  
Contrast Enhanced ◽  
Significant Difference ◽  
Mri Scans ◽  
Magnetic Resonance Imaging Mri ◽  
Contrast Enhanced Mri

AbstractTo directly compare and describe the differences between juvenile idiopathic arthritis (JIA) patients and pediatric controls regarding features of the synovial and tenosynovial membrane on contrast-enhanced magnetic resonance imaging (MRI) of the wrist. T1-weighted contrast-enhanced MRI scans of 25 JIA patients with clinically active wrist arthritis and 25 children without a history of joint complaints nor any clinical signs of joint inflammation were evaluated by two readers blinded to clinical data. The synovium was scored at five anatomical sites based on thickening of the synovium (0–3 scale) and synovial enhancement (0–2 scale). Thickening and/or enhancement of the tenosynovium was scored at four anatomical sites using a 0–3 scale. Significantly higher scores for synovial thickening (median 4 vs. 1, p < 0.001) and synovial enhancement (median 4 vs. 1, p < 0.001) are found in the wrist of JIA patients as compared to controls. JIA patients experienced the highest synovial scores at the mid-/inter-carpal, 2nd –5th carpometacarpal, and radiocarpal joints. No significant difference in tenosynovial scores is found between both groups (median 0 vs. 0, p = 0.220). This study highlights the higher synovial thickening/enhancement scores on contrast-enhanced MRI of the wrist in JIA patients compared to pediatric controls. Tenosynovial thickening and/or enhancement was rarely present in both groups. In JIA patients, synovial thickening and enhancement were particularly present at three anatomical sites. These results substantially support rheumatologists and radiologists when navigating through MRI of the wrist in search for JIA disease activity.

scholarly journals Enhancement of Ovarian Malignancy on Clinical Contrast Enhanced MRI Studies

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Harpreet K. Pannu ◽  
Weining Ma ◽  
Emily Craig Zabor ◽  
Chaya S. Moskowitz ◽  
Richard R. Barakat ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Serous Carcinoma ◽  
High Grade ◽  
Borderline Tumors ◽  
Enhanced Mri ◽  
Mri Studies ◽  
Contrast Enhanced ◽  
Significant Difference ◽  
Mri Scans ◽  
Contrast Enhanced Mri

Purpose. To assess if there is a significant difference in enhancement of high grade serous carcinoma of the ovary compared with other ovarian malignancies on clinically performed contrast enhanced MRI studies. Methods. In this institutional-review–board-approved study, two radiologists reviewed contrast enhanced MRI scans in 37 patients with ovarian cancer. Readers measured the signal intensity (SI) of ovarian mass and gluteal fat pre- and postcontrast administration. Percentage enhancement (PE) was calculated as [(post-pre)/precontrast SI] × 100. Results. Pathology revealed 19 patients with unilateral and 18 patients with bilateral malignancies for a total of 55 malignant ovaries-high grade serous carcinoma in 25/55 ovaries (45%), other epithelial carcinomas in 12 ovaries (22%), nonepithelial cancers in 8 ovaries (14%), and borderline tumors in 10 ovaries (18%). Enhancement of high grade serous carcinoma was not significantly different from other invasive ovarian malignancies (Reader 1 ; Reader 2 ). Enhancement of invasive ovarian malignancies was more than borderline tumors but did not reach statistical significance (Reader 1; Reader 2 ). Conclusion. On clinically performed contrast enhanced MRI studies, enhancement of high grade serous ovarian carcinoma is not significantly different from other ovarian malignancies.

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