scholarly journals Associations between pre-pregnancy body mass index, gestational weight gain and preterm birth: a cohort study in Wuhan, China

2020 ◽  
Author(s):  
Yiyang Guo ◽  
Chao Xiong ◽  
Aifen Zhou ◽  
Ronghua Hu ◽  
Rong Yang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Weight Gain ◽  
Preterm Birth ◽  
Gestational Weight Gain ◽  
Early Pregnancy ◽  
Chinese Women ◽  
Tracking System ◽  
Mortality And Morbidity ◽  
Gestational Weight ◽  
Increased Risk

Abstract Background Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity worldwide. Methods This cohort study aims to investigate the associations between pre-pregnancy BMI, total gestational weight gain (GWG), and the GWG during early pregnancy with PTB utilizing data of 83,096 Chinese women from the Wuhan Maternal and Children Healthcare Information Tracking System in China. Results Women who were underweight, overweight or obese before pregnancy had an higher overall risk of PTB compared with the normal group. Women who with a total GWG below the IOM recommendation had an increased risk of PTB compared to women who had GWG within the recommendation, whereas increased weekly early pregnancy GWG had a significant impact on the increasing risk of PTB. When stratified by subtypes of PTB, pre-pregnancy underweight was associated with higher risk of spontaneous PTB, and pre-pregnancy overweight /obese increased the risk of both spontaneous PTB and medically indicated PTB. Women with total GWG below the IOM recommendation had elevated risk for spontaneous PTB and PROM, and women with GWG above the recommendation had decreased risk for all three subtypes of PTB, whereas risk for the three subtypes of PTB increased along with increasing weekly GWG of early pregnancy. Conclusions Maternal underweight, overweight/obesity, total GWG, and GWG during early pregnancy should be considered in combination to reduce the risk of PTB, women should modify their weight gains during pregnancy according to the results.

scholarly journals Associations Between Pre-Pregnancy Body Mass Index, Gestational Weight Gain and Preterm Birth: a Cohort Study in Wuhan, China

2020 ◽  
Author(s):  
Yiyang Guo ◽  
Chao Xiong ◽  
Aifen Zhou ◽  
Ronghua Hu ◽  
Rong Yang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Weight Gain ◽  
Preterm Birth ◽  
Gestational Weight Gain ◽  
Early Pregnancy ◽  
Tracking System ◽  
Normal Weight ◽  
Elevated Risk ◽  
Gestational Weight ◽  
Increased Risk

Abstract Background Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity worldwide. Methods This cohort study was designed to investigate the associations between pre-pregnancy BMI, total gestational weight gain (GWG), and GWG during early pregnancy with PTB utilizing data of 83,096 Chinese women from the Maternal and Children Healthcare Information Tracking System of Wuhan, China. Results Women who were underweight, overweight or obese prior to pregnancy had an overall elevated risk of PTB, compared to their normal weight counterparts. Women with total GWG below the IOM recommendation had an increased risk of PTB compared to women who had GWG within the recommendation, whereas an increasing risk of PTB was observed asweekly early pregnancy GWGincreased. When stratified by subtypes of PTB, pre-pregnancy underweight was associated with higher risk of spontaneous PTB, and pre-pregnancy overweight /obese increased the risk of both spontaneous PTB and medically indicated PTB. Women with total GWG below the IOM recommendation had elevated risk for spontaneous PTB and PROM, and women with GWG above the recommendation had decreased risk for all three subtypes of PTB, whereas risk for the three subtypes of PTB increased along with increasing weekly GWG of early pregnancy. Conclusions Maternal underweight, overweight/obesity, total GWG, and GWG during early pregnancy should be considered in combination to reduce the risk of PTB, women should modify their weight gains during pregnancy according to the results.

scholarly journals Independent effect of gestational weight gain and prepregnancy obesity on pregnancy outcomes among Saudi women: A sub-cohort analysis from Riyadh mother and baby cohort study (RAHMA)

PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0262437
Author(s):  
Amel Fayed ◽  
Hayfaa A. Wahabi ◽  
Samia Esmaeil ◽  
Roaa Elkouny ◽  
Hala Elmorshedy ◽  
...  
Keyword(s):  
Cohort Study ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Pregnancy Outcomes ◽  
Cohort Analysis ◽  
Adverse Outcomes ◽  
Independent Effect ◽  
Gestational Weight ◽  
Increased Risk ◽  
Prepregnancy Obesity

Background Gestational weight gain (GWG) and prepregnancy obesity are garnering more attention as determining factors of pregnancy outcomes when it comes to the wellbeing of both the mother and her baby. This study was conducted to describe the pattern of GWG among participants of Riyadh Mother and Baby Multicenter Cohort Study (RAHMA) and to investigate the detrimental effects of excessive GWG and prepregnancy obesity on pregnancy outcomes. Methods RAHMA is a multicentre cohort study conducted in three hospitals in Riyadh, Saudi Arabia. Participants were categorized according to the Institute of Medicine into inadequate, adequate, and excessive GWG, and stratified by body mass index (BMI) into under/normal weight, overweight, and obese. To examine the independent effect of maternal prepregnancy obesity and GWG, a multivariate regression model was used and adjusted odds ratio (AOR) and 95% Confidence Interval (CI) for each outcome were calculated. Results A total of 7029 participants were included in this study; 31.8% had adequate GWG, 25.9% had excessive GWG and 42.3% had inadequate GWG, while 29.7% had normal BMI, 33.3% were overweight, 34.8% were obese, and 2.2% were underweight. Excessive GWG was independently associated with increased risk of hypertensive events, (AOR = 1.77, 95% CI 1.20–2.63). Obesity was associated with higher risk of gestational diabetes (AOR 2.11, 95% CI 1.76–2.53), hypertensive events (AOR 2.06, 95% CI 1.48–3.01), and delivery by emergency caesarean section (AOR = 1.63, 95% CI 1.35–1.97). Infants of obese women had increased odds of macrosomia (AOR 3.11, 95% CI 1.94–4.99) and lower odds of low birth weight (AOR = 0.68, 95% CI 0.53–0.88). Conclusion In comparison to excessive GWG, which increases the risk of hypertensive events during pregnancy, prepregnancy obesity is associated with more adverse outcomes including GDM, hypertensive events in pregnancy and emergency CS.

scholarly journals The Association between Pre-Pregnancy BMI, Gestational Weight Gain and Pregnancy Outcomes: A Retrospective Cohort Study in Ahvaz, Iran

2020 ◽  
Author(s):  
Kambiz Ahmadi Angali ◽  
Maryam Azhdari ◽  
Maria Cheraghi ◽  
parvin shahri ◽  
shokrolah salmanzadeh ◽  
...  
Keyword(s):  
Health Care ◽  
Body Mass Index ◽  
Cohort Study ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Gestational Age ◽  
Retrospective Cohort ◽  
Large For Gestational Age ◽  
Gestational Weight ◽  
Increased Risk

Abstract Background: Maternal body mass index and maternal gestational weight gain can have positive effects on birth and maternal outcomes. We aimed to identify the effect of pre-pregnancy weight and gestational weight gain on birth outcomes.Methods: Data of this retrospective cohort study were extracted using the 1457 out of 1800 pair health records belonged to the pregnant mother and infant at Ahvaz health care centers, from 2010 to 2018.Result: The 3.18-fold increased risk for large for gestational age in overweight mothers, and a 2.9 fold increased risk for small for gestational age in those mothers with gestational weight gain below the guidelines. An increased risk of large for gestational age, low birth weight, and macrosomia were observed in overweight mothers with gestational weight gain out of the guidelines. The increased association was found between the maternal pre-body mass index and fasting blood sugar (p = 0.0001). Hence, hyperglycemia is related to a 3.58-fold incidence of macrosomia. Conclusion: Therefore, conducting more educational programs of lifestyle intervention with respect to reproductive health care is required for all women in childbearing age (before and during pregnancy), with the purpose of reducing the adverse pregnancy outcome.

scholarly journals Investigation of optimal gestational weight gain based on the occurrence of adverse pregnancy outcomes for Chinese women: a prospective cohort study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Yin Sun ◽  
Zhongzhou Shen ◽  
Yongle Zhan ◽  
Yawen Wang ◽  
Shuai Ma ◽  
...  
Keyword(s):  
Cohort Study ◽  
Weight Gain ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Pregnancy Outcomes ◽  
Chinese Women ◽  
Normal Weight ◽  
Adverse Pregnancy Outcomes ◽  
Gestational Weight ◽  
Adverse Pregnancy

Abstract Objective To investigate recommendations for appropriate gestational weight gain (GWG) of Chinese females. Methods In total of 3,172 eligible women in the first trimester were recruited into the Chinese Pregnant Women Cohort Study (CPWCS) project. Pregnancy complications and outcomes were collated using the hospital medical records system. The method of occurrence of participants with adverse pregnancy outcomes (Occurrence Method) was conducted to calculate the recommended total GWG for each participant’s pre-pregnancy BMI. Occurrence Method data were judged against the Institute of Medicine (IOM) and Japanese recommended criteria in terms of the total occurrence of adverse pregnancy outcomes of pregnant women with appropriate weight gain. Results The most frequent GWG was ≥ 14 kg and < 16 kg (19.4%), followed by ≥ 10 kg and < 12 kg (15.5%) and ≥ 12 kg and < 14 kg (15.2%). The most frequently occurring adverse pregnancy outcomes were cesarean sections for underweight (30.0%), normal weight (40.4%), overweight (53.6%) and obese (53.7%) women. A large for gestational age (LGA) accounted for 18.0% of the overweight and 20.9% of the obesity group. Gestational diabetes mellitus (GDM) occurred in 16.9% of overweight and 23.1% of obese women. The recommended total GWG in a Chinese women population is ≥ 8 and < 12 kg if underweight, ≥ 12 and < 14 kg for normal weight, ≥ 8.0 and < 10.0 kg if overweight, and < 8 kg for women with obesity. Conclusions Current Chinese recommendations provide the optimal ranges of GWG to minimize the occurrence of undesirable pregnancy outcomes for each group of pre-pregnancy BMIs in a Chinese population. Trial registration Registered with ClinicalTrials (NCT03403543).

scholarly journals Gestational Weight Gain During the Second and Third Trimesters and Adverse Pregnancy Outcomes, Results From a Prospective Pregnancy Cohort in Urban Tanzania

2021 ◽  
Author(s):  
Jiaxi Yang ◽  
Molin Wang ◽  
Deirdre K. Tobias ◽  
Janet W. Rich-Edwards ◽  
Anne Marie Darling ◽  
...  
Keyword(s):  
Weight Gain ◽  
Preterm Birth ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Early Pregnancy ◽  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Gestational Weight ◽  
Pregnancy Cohort ◽  
Adverse Pregnancy

Abstract Background Appropriate gestational weight gain (GWG) is important for optimal pregnancy outcomes. This study prospectively evaluated the associations between GWG during the second and third trimesters of pregnancy and adverse pregnancy outcomes in an urban Tanzanian pregnancy cohort. Methods We used data from a randomized clinical trial conducted among pregnant women recruited by 27 weeks of gestation in Dar es Salaam, Tanzania (N = 1,230). Women’s gestational weight was measured at baseline and at monthly antenatal visits. Weekly GWG rate during the second and third trimesters was calculated and characterized as inadequate, adequate, or excessive, in conjunction with measured or imputed early-pregnancy BMI status according to the 2009 Institute of Medicine (IOM) GWG guidelines. We used multivariable Poisson regression with a sandwich variance estimator to calculate risk ratios (RR) for associations of GWG with low birth weight, preterm birth, small for gestational age (SGA), and large for gestational age (LGA). Degree of appropriate GWG defined using additional metrics (i.e., percentage of adequacy, z-score) and potential effect modification by maternal BMI were additionally evaluated. Results According to the IOM guidelines, 517 (42.0%), 270 (22.0%), and 443 (36.0%) women were characterized as having inadequate, adequate, and excessive GWG, respectively. Overall, compared to women with adequate GWG, women with inadequate GWG had a lower risk of LGA births (RR=0.54, 95% CI: 0.36 - 0.80) and a higher risk of SGA births (RR=1.32, 95% CI: 0.95 - 1.81). ­­Women with inadequate GWG as defined by percentage of GWG adequacy had a higher risk of LBW (OR=1.93, 95% CI: 1.03 - 3.63). In stratified analyses by early-pregnancy BMI, excessive GWG among women with normal BMI was associated with a higher risk of preterm birth (RR=1.59, 95% CI: 1.03 - 2.44). Conclusions A comparatively high percentage of excessive GWG was observed among healthy pregnant women in Tanzania. Both inadequate and excessive GWGs were associated with elevated risks of poor pregnancy outcomes. Future studies among diverse SSA populations are warranted to confirm our findings, and clinical recommendations on optimal GWG should be developed to promote healthy GWG in SSA settings. Trial registration This trial was registered as “Prenatal Iron Supplements: Safety and Efficacy in Tanzania” (NCT01119612; http://clinicaltrials.gov/show/NCT01119612).

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