Stereodivergent Propargylic Alkylation of Enals via Cooperative NHC and Copper Catalysis

2021 ◽  
Author(s):  
Yu-Hua Wen ◽  
Zi-Jing Zhang ◽  
Shuai Li ◽  
Jin Song ◽  
Liu-Zhu Gong
Keyword(s):  
Building Block ◽  
Heterocyclic Carbenes ◽  
Copper Catalysis ◽  
Great Success ◽  
Reactive Site ◽  
Alkaloid Synthesis ◽  
The Creation ◽  
The Rich

Abstract Despite that asymmetric stereodivergent synthesis has experienced great success to provide unusual processes for the creation of chirality complexity, concepts appliable to asymmetric stereodivergent catalysis are still limited. The dependence on the unusual capacity of each catalyst to precisely control the reactive site planar in the region poses unparalleled constraint on this field. Here, we first demonstrate that the chiral Cu-allenylidene species can participate in the stereodivergent propargylic alkylation of enals, in concert with chiral N-heterocyclic carbenes (NHCs). Thus, all four stereoisomers were obtained with excellent enantioselectivity and diastereoselectivity (up to >99% e.e. and >95:5 d.r.) from the same starting materials by simply altering chiral Cu-Pybox complex and NHC combinations. The rich chemistry workable in the products enables the structurally diverse synthesis of chiral functional molecules and holds great potential in alkaloid synthesis, as showcased by the preparation of the key building block to access (-)-perophpramidine.

scholarly journals Breyten Breytenbach en die Simbolisme - ’n voorlopige verkenning

Literator ◽  
1992 ◽  
Vol 13 (1) ◽  
pp. 15-28 ◽  
Author(s):  
H. Viljoen
Keyword(s):  
Cape Town ◽  
Strong Duality ◽  
Great Emphasis ◽  
Rich Source ◽  
The Creation ◽  
Breyten Breytenbach ◽  
The Rich ◽  
The Difference ◽  
Present World

This article is an attempt to outline the difference between Breytenbach's poetic method and that of the Symbolists. Although it touches on aspects of the symbolist poetic method like the rich suggestiveness, the creation o f a meaningful alternative world (and the effort of doing this), it focuses mainly on Breytenbach’s use of metaphor to create an impossible alternative world in a poem, only to relativize and destroy it again in the end. This process is illustrated in an analysis of poem 8.1 from Lotus. This analysis also shows up five well-known cardinal traits of Breytenbach’s poetry, viz. its carnality, the universal analogy between body, cosmos and poetry and the great emphasis on journeys, discoveries and transformations by means of language. It is also claimed that the Zen-Buddhisi Void plays an analogous role in Breytenbach's poetry to the theory of correspondances in the Symbolists: it is a rich source of metaphor. Breytenbach's poetry shows a strong duality between the present world and a meaningful alternative sphere. Being in and of this alternative sphere only aggravates the poet’s isolation (a typically symbolist trait), making him literally and figuratively an exile, as exile poems like "tot siens, kaapstad" (see you again, cape town) and "Walvis in die berg" (Whale on the mountain) and, of course, his prison poetry, clearly show.

Organocatalytic upgrading of the key biorefining building block by a catalytic ionic liquid and N-heterocyclic carbenes

2012 ◽  
Vol 14 (10) ◽  
pp. 2738 ◽  
Author(s):  
Dajiang (D. J.) Liu ◽  
Yuetao Zhang ◽  
Eugene Y.-X. Chen
Keyword(s):  
Ionic Liquid ◽  
Building Block ◽  
Heterocyclic Carbenes

Genetic Art and the Aesthetics of Biology

Leonardo ◽  
2002 ◽  
Vol 35 (2) ◽  
pp. 137-144 ◽  
Author(s):  
Steve Tomasula
Keyword(s):  
Biological Materials ◽  
Genetically Engineered ◽  
Aesthetic Judgment ◽  
Art And Science ◽  
Work Of Art ◽  
Traditional Art ◽  
Biological Form ◽  
The Creation ◽  
The Rich ◽  
Traditional Artists

The creation of Alba, the first mammal genetically engineered to be a work of art, accents the increasing number of artists who take as their medium plants, cells, genes and other biological materials. Like traditional artists, these bioartists raise traditional art issues; but since their work collapses the gap between art and science, representation and biological form, they also marry the rich tradition of manipulating nature for aesthetic reasons, the ethical complexities created by today's biotech revolution and the historical ramifications of applying aesthetic judgment to humans.

scholarly journals COLORS INFLUENCE SOCIETY

2014 ◽  
Vol 2 (3SE) ◽  
pp. 1-2
Author(s):  
Sadhana Chauhan
Keyword(s):  
Human Mind ◽  
Literary Discourse ◽  
First Ray ◽  
The Creation ◽  
The Rich ◽  
The Relationship

The relationship between nature and man has been the center of philosophy, art and literary discourse from the ancient end of contemplation to the present. Therefore, color is also not untouched by this. "When the first ray of sun falls on an object, then that object becomes colored. A color touches you in such a way that many dreams begin to awaken in your imagination. Sometimes a color fascinates you in such a way that you start living the verses of life in harmony with it. And sometimes a color in your memory keeps you cheerful. "1 picture is a way of expressing the human mind. In the periphery of Malwa, the aforesaid shilachitra are found in various forms in Bhima Betka. From the pieces found there, from the Gheru, the Hidemachi and the Magenich, it is known that the paintings made from them were made there. In the context of the pictures and the sensations, adornment, memory, mystery and the configurations made of them, the center of the creation of colors is targeted only in the direction of the rich creation of colors. Any painting is based on the foundation of the interrelation of colors. "3 प्रकृति और मनुष्य का रिश्ता चिंतन के प्राचीन छोर से वर्तमान तक दर्शन, कला और साहित्यिक विमर्श का केन्द्र रहा है। अतः रंग भी इस से अछूते नहीं है।’’सूरज की पहली किरण जब किसी वस्तु पर पड़ती है तब वह वस्तु रंगमय हो जाती है। कोई रंग आपको इस तरह छूता है कि आपकी कल्पना में कई ख्वाब जागने लगते हैं। कभी कोई रंग आपको इस तरह मोहित कर लेता है कि आप उसके साथ लय मिलाते हुए जीवन का छंद जीने लगते हैं। और कभी कोई रंग आपकी स्मृति में ठहर आपको प्रफुल्लित रखता है।’’1 चित्र मानवीय मन को अभिव्यक्त करने का एक जरिया है। ’’मालवा की परिधि में पूर्वोक्त शिलाचित्र भीम बेटका में विविध रुप में प्राप्त होते हैं। गेरु, हिड़मची और मेगेनीच के वहां से प्राप्त टुकड़ों से ज्ञात होता है कि उनसे निर्मित रंगो से वहां चित्र बनाये जाते थे।’’2 एक चित्रकृति अपने में समाहित सौंदर्य को रंगो से परिपूर्ण करती है। चित्रों के संदर्भ में और उनसे प्रकट होने वाली अनुभूति, श्रृंगारिकता, स्मृति, रहस्य और इन सब से निर्मित विन्यास के केन्द्र में रंगो की विपुल सृष्टि का समाहन ही लक्षित होता है। कोई भी चित्रकृति रंगों के अंतर्सम्बन्ध की बुनियाद पर आधारित है।’’3

scholarly journals SCIENTIFIC BASE OF CULTURAL AND EDUCATIONAL ACTIVITIES IN THE PALEONTOLOGICAL MUSEUM OF LIAONING IN CHINA

2020 ◽  
pp. 236-241
Author(s):  
Tengfei Liu ◽  
Keyword(s):  
Natural History ◽  
Liaoning Province ◽  
Main Task ◽  
Russian Scientist ◽  
Educational Activities ◽  
Popularization Of Science ◽  
History Of ◽  
The Creation ◽  
The Rich ◽  
Scientific Base

The article covers the formation of the scientific base for working with visitors at the Paleontological Museum of Liaoning in China. The original reason for the creation of the museum is stated, it was connected with 1990s, when numerous fossils were discovered in Liaoning province. The first of them were Sinosauropteryx and the Liaoning ancient fruit (Archaefructus liaoningensis). Later large number of fossils were discovered, they represent the flora and fauna of China existed more than 3 billion years ago. It is important to say that the Liaoning Provincial Department of Land Resources and Shenyang University saw scientific value of the paleontological findings. They decided to build a paleontological museum on a parity basis. Construction of the museum building at Shenyang University began in 2006, and the Paleontological Museum of Liaoning was opened in 2011. The world-famous paleontologists contributed immensely to the formation of the Paleontological Museum of Liaoning. They are Sun Ge (Chinese researcher), M.A. Akhmetyev (Russian scientist), F. Mosbrugger (director of the Museum of Natural History of Germany), K. Johnson (director of the Smithsonian National Museum of Natural History, Washington, USA) and professor P. Godfroy (Royal Institute of Natural History of Belgium). The staff of the Liaoning Museum, part-time researchers, as well as student volunteers of the Shenyang University participated in the development of the museum resources. Thanks to joint hard work, the museum has collected more than 30 thousand paleontological fossils. At present, the collection of the Liaoning Museum includes all kinds of animals and plants of ancient China, they are subdivided into seven classification groups. The reliance on the rich resources of the museum ensured the creation of the exposition, which occupies eight exhibition halls. They exhibit genuine monuments of paleontology, as well as replicas and models. They acquaint visitors with the ancient world of China, communicate the geological history of the Liaoning province, and reveal the kingdom of dinosaurs. The author of article emphasizes that in 2011, when the museum was opened, a department for the popularization of science was formed along with other departments. The main task of the workers of this department was to carry out cultural and educational activities with specialists and ordinary visitors. The department organizes exhibitions in China and abroad, conducts seminars for workers of Chinese nature museums. The scientific and educational section within the department for popularization of science also work with schoolchildren. During the first nine years of the museum's creation, three million single visitors and twenty thousand social groups have visited Paleontological Museum of Liaoning. So the article reveals the importance of cultural and educational activities that ensures the cooperation of the Liaoning Museum with other schools and museums in China, brings the museum to the international level.

The Holy War (1682)

2018 ◽  
Author(s):  
Nancy Rosenfeld
Keyword(s):  
Great Success ◽  
John Bunyan ◽  
Human Soul ◽  
Holy War ◽  
Literary Works ◽  
Life And Death ◽  
Pilgrim's Progress ◽  
Future Events ◽  
The Creation ◽  
Literary Characters

By the early 1680s John Bunyan had achieved respect and popularity for his public preaching. As an author he attempted to build on the great success of The Pilgrim’s Progress, first with The Life and Death of Mr. Badman (1680) and then with The Holy War, which was published in 1682. Bunyan’s most ambitious and elaborate work of fiction took the form of an allegorical battle epic depicting the Christian scheme of salvation, the struggle of the human soul towards salvation, and contemporary and future events. This chapter discusses The Holy War in the context of the religious and literary works available to Bunyan, and as an impressive example of Bunyan’s skill in the creation of individuated literary characters.

Т.СЫДЫКБЕКОВДУН «КӨК АСАБА» РОМАНЫНДАГЫ ФРАЗЕОЛОГИЗМДЕРДИН

2020 ◽  
pp. 16-19
Author(s):  
Аттокур Джапанов
Keyword(s):  
Great Success ◽  
Complex Phenomenon ◽  
Work Of Art ◽  
Full Version ◽  
Quantum Version ◽  
The Creation ◽  
The Aesthetic ◽  
Lexical Variant

Аннотация: Фразеологизмдердин варианттары өзүлөрүнүн жасалышы, пайда болуш мүнөздөрү боюнча бирдей эмес. Алар тутумуна сөз кошулуу, экинчисинде бир компоненттин башка сөз менен алмаштыруу жана үчүнчүсүндө компоненттердин өз ара орун алмаштыруу аркылуу жасалат. Көркөм чыгарма жаратууда фразеологизмдердин лексикалык варианттарын колдонуу стилистикалык аспектиден алганда да татаал кубулуш, ал кепте анын маданияттуулугун көтөрүү стилди жакшыртуу максаттарын ишке ашырууда табылгыс тилдик каражат болуп саналат. Т.Сыдыкбеков бул максатта лексикалык кордогу фразеологизмдердин айрым бөлүктөрүн башка сөз менен алмаштыруу аркылуу зор ийгиликтерге жетишкен. Мындай сөздөрдүн түгөйлөрүн колдонуу чыгармага эстетикалык мазмун жаратып, автордун кебинин маданияттуулугун арттырган. Квантативдик вариантта фразеологизмдин толук вариантынан айрым бир компоненттеринин кыскартылып айтылышынан, же тескерисинче, анын табиятына мүнөздүү болбогон башка бир сөздүн кошулуп айтылышынан фразеологизм-дин негизги маанисине доо кетпейт. Түйүндүү сөздөр: фразеологизм, компонент, лексикалык вариант, квантативик вариант, "көк асаба", публицисттер. Аннотация: Варианты фразеологизмов неоднородны по своему строению, характеру возникновения. Они создаются путем присоединения слова к системе, замена одного компонента другим словом и взаимозаменяемости компонентов третьего. Использование лексических вариантов фразеологизмов в создании художественного произведения-сложное явление даже в стилистических аспектах, которое является незаменимым языковым средством в реализации целей улучшения стиля, повышения его культуры. С этой целью Т.Сыдыкбеков добился больших успехов путем замены некоторых фразеологизмов лексического корня другими словами. Использование пар таких слов создало эстетическое содержание произведения, повысило культурность внешности автора. Из полного варианта фразеологизма в квантативном варианте не вытекает искушение основного значения фразеологизма из сокращенного произношения отдельных компонентов, или, наоборот, сложного произношения другого слова, не характерного для его природы. Ключевые слова: фразеологизм, компонент, лексический вариант, квантативный вариант, публицисты. Abstract: the variants of phrase logical units are heterogeneous in their structure and origin. They are created by attaching a word to the system, replacing one component with another word, and interchanging the components of a third. The use of lexical variants of phrase logical units in the creation of a work of art is a complex phenomenon, even in stylistic aspects, which is an indispensable language tool in the implementation of the goals of improving the style, increasing its culture. To this end, T.Sydykbekov achieved great success by replacing some phrase logical units of the lexical root with other words. The use of pairs of such words created the aesthetic content of the work, increased the words created the aesthetic content of the work, increased the cultural appearance of the author. И The full version of phraseology in the quantum version does not lead to the temptation of the main meaning of phraseology from the abbreviated pronunciation of individual components, or, conversely, the complex pronunciation of another word that is not characteristic of its nature. Keywords: phraseology, component, lexical variant, quantiative variant, publicists.

Creating Successful Portals with a Design Framework

2009 ◽  
Vol 1 (4) ◽  
pp. 63-75 ◽  
Author(s):  
Joe Lamantia
Keyword(s):  
Building Block ◽  
Large Scale ◽  
Building Blocks ◽  
Design Principles ◽  
Design Framework ◽  
Block System ◽  
Business Information ◽  
Social Settings ◽  
The Creation ◽  
Over Time

Portal designers and managers face the difficulties of creating effective information architectures for portals, dashboards, and tile-based platforms for delivering business information and functionality using only flat portlets. This article introduces the idea of a system of standardized building blocks that can simplifies portal design and management, and effectively support growth in content, functionality, and users over time. In enterprise and other large scale social settings, using standardized components allows for the creation of a library of tiles that can be shared across communities of users. It then outlines the design principles underlying the building block system, and the simple guidelines for combining blocks together to create any type of tile-based environment.

Creating Successful Portals with a Design Framework

2011 ◽  
pp. 246-256
Author(s):  
Joe Lamantia
Keyword(s):  
Building Block ◽  
Large Scale ◽  
Building Blocks ◽  
Design Principles ◽  
Design Framework ◽  
Block System ◽  
Social Settings ◽  
The Creation ◽  
Over Time

Portal practitioners face the difficulties of creating effective information architectures for portals, dashboards, and tile-based information environments using only flat portlets. This article introduces the idea of a system of standardized building blocks that can effectively support growth in content, functionality, and users over time. In enterprise and other large scale social settings, using standardized components allows for the creation of a library of tiles that can be shared across communities of users. It then outlines the design principles underlying the building block system, and the simple guidelines for combining blocks together to create any type of tile-based environment.

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