scholarly journals A Systematic Review of Implementation Science Frameworks in Cancer Prevention Interventions: An Exploratory Health Disparities Analysis

Author(s):  
Serena Xiong ◽  
Hamdi I. Abdi ◽  
Rahel Ghebre ◽  
Shalini Kulasingam ◽  
DeAnn Lazovich ◽  
...  

Abstract Background: A growing number of studies have used implementation science (IS) frameworks, such as RE-AIM, to inform and evaluate the implementation of evidence-based cancer prevention services (e.g., cancer screening); however, the impact of such applications is not well understood, including whether the use of an IS framework can lead to reductions in health disparities. The purpose of this systematic review is to explore how IS frameworks can guide adaptations to cancer prevention services to specifically address health disparities. Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered with PROSPERO. Searches were conducted in Ovid MEDLINE, PubMed, PsycINFO, CINAHL, and EMBASE. Search strategies used a combination of terms related to implementation science frameworks, cancer prevention, and/or intervention. All searches were conducted between January to May 2020. The QATSDD tool was used to assess the quality of studies included in the review. Results: A total of 1,025 titles and abstracts were screened, and 84 were deemed eligible for full-text screening. After full-text screening, n=27 articles were included for data abstraction and synthesis. Of the 27 studies that were included, an overwhelming majority (n=19, 70.3%) were based in the United States, utilized mixed-methods (n=12, 44.4%), focused only on a single cancer site (n=21, 81.5%), and took place in a health system (n=18, 66.7%). Approximately half of the studies (n=13, 48.2%) used an IS framework for post-implementation evaluation. Most notably, only one-third of studies (n=9, 33.3%) used an IS framework to address cancer-related health disparities. Of those nine studies, six (66.7%) of them used the Consolidated Framework for Implementation Research (CFIR). Other IS frameworks that were used to inform a health disparities adaptation were Diffusion of Innovations, Knowledge-To-Action, and RE-AIM. Most studies were at moderate risk of bias (n=19, 70.4%).Conclusion: Across the various cancer prevention studies that have been implemented, CFIR has been the dominant IS framework used to address health disparities. The application of such frameworks, however, has been used in pre-implementation and planning studies. It remains to be seen if IS frameworks used within a health disparities context in cancer prevention interventions can reduce cancer-related outcomes.Trial registration: PROSPERO CRD42020171970

Author(s):  
Jyotsana Parajuli ◽  
Judith E. Hupcey

The number of people with cancer and the need for palliative care among this population is increasing in the United States. Despite this growing need, several barriers exist to the utilization of palliative care in oncology. The purpose of this study was to synthesize the evidence on the barriers to palliative care utilization in an oncology population. A systematic review of literature was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, CINAHL, and Psych Info databases were used for the literature search. Articles were included if they: 1) focused on cancer, (2) examined and discussed barriers to palliative care, and c) were peer reviewed, published in English, and had an accessible full text. A total of 29 studies (8 quantitative, 18 qualitative, and 3 mixed-methods) were identified and synthesized for this review. The sample size of the included studies ranged from 10 participants to 313 participants. The barriers to palliative care were categorized into barriers related to the patient and family, b) barriers related to providers, and c) barriers related to the healthcare system or policy. The factors identified in this review provide guidance for intervention development to mitigate the existing barriers and facilitate the use palliative care in individuals with cancer.


2021 ◽  
pp. 019459982110394
Author(s):  
Braeden Lovett ◽  
Alexandra Welschmeyer ◽  
James Dixon Johns ◽  
Sarah Mowry ◽  
Michael Hoa

Objective Social determinants of health (SDOHs), including but not limited to sex, race, socioeconomic status, insurance status, and education level, play a significant role in health disparities and affect health outcomes. The purpose of this systematic review is to examine health disparities in otology within the United States and highlight areas warranting further research. Data Sources PubMed, Ovid MEDLINE. Review Methods Our search encompassed all years through January 10, 2021. All peer-reviewed primary literature of any design and publication date regarding health disparities and otology outcomes in the United States was eligible for inclusion. Eligibility assessment was performed via 3 independent investigators. Results Of the 6326 unique abstracts identified, 188 studies underwent full-text review, and 52 remained in the final review. The most frequently examined otologic condition was hearing loss (36.5%), followed by cochlear implantation (28.8%) and infection/effusion (15.4%). Vertigo/dizziness (1.9%), Ménière’s disease (1.9%), and tinnitus (1.9%) were the least represented otologic conditions. Comprehensive articles on multiple disparity topics were the most common (n = 18), followed by articles on race/ethnicity (n = 11) and socioeconomic status (n = 9). Language (n = 2), education (n = 2), and gender (n = 1) were the least discussed. Over 5-fold the number of articles were published between 2011 and 2020 compared to the preceding decade (42 vs 8). Conclusion This study captures the existing literature regarding health disparities and outcomes in otology. The lack of robust data suggests the need for future quality studies aimed at investigating disparities in otologic care, as well as a broader push for recording and reporting SDOHs.


Hand ◽  
2017 ◽  
Vol 13 (5) ◽  
pp. 509-515 ◽  
Author(s):  
Jessica L. Truong ◽  
Chris Doherty ◽  
Nina Suh

Background: Socioeconomic factors are known to affect outcomes for both medical and surgical conditions. The purpose of this systematic review was to assess the current evidence regarding the effect of socioeconomic factors such as income, geographic location, educational level, and occupation on clinical outcomes after distal radius fractures. Methods: A systematic search strategy was performed to identify studies commenting on the effect of socioeconomic factors on clinical outcomes following open or closed distal radius fracture repair. Abstract and full-text screening was performed by 2 independent reviewers, and articles were evaluated by Structured Effectiveness Quality Evaluation Scale (SEQES). Treatment outcomes of interest included, but were not limited to, pain, function, range of motion, and grip strength. Results: There were 1745 studies that met our inclusion and exclusion criteria for abstract screening. Of these, 48 studies met our inclusion criteria for full-text screening and 20 studies met our criteria for quality analysis with the SEQES score. There were 3 studies of high quality, 16 of moderate quality, and 1 of low quality. Meta-analyses were not possible due to the variability in outcomes of interest across papers. Conclusions: Patient factors indicative of socioeconomic status are relevant predictors of functional outcome after distal radius fractures. There is currently limited evidence in this area of research, and further examination should be considered to improve outcomes from a patient and system standpoint.


AIDS ◽  
2021 ◽  
Vol 35 (2) ◽  
pp. 177-191
Author(s):  
Sylvia Shangani ◽  
Nidhi Bhaskar ◽  
Natasha Richmond ◽  
Don Operario ◽  
Jacob J. van den Berg

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Mohamed Sarraj ◽  
Daniel E Axelrod ◽  
Sarah Zhu ◽  
Herman Johal

Femoral shaft fractures are devastating injuries that usually result from high-energy mechanisms in victims of poly-trauma. Reamed and statically locked intramedullary nailing (IMN) is the definitive treatment modality for femoral shaft fractures. Patients are most commonly positioned either supine or lateral decubitus. There remains considerable concern regarding the safety of lateral positioning in the traumatized patient, particularly in the management of a potentially difficult airway or concomitant C-spine injuries. We therefore undertook a systematic review of intraoperative positioning among patients with femoral shaft fractures following PRISMA guidelines. Title and abstract screening, full text screening, and data abstraction were all completed in duplicate. Methodological Index for Nonrandomized Studies (MINORS) scores were used to evaluate methodological quality. Results: 3018 studies were included in initial screening, with three studies ultimately meeting all inclusion criteria. A total of 1,949 patients were analyzed, with 684 patients treated in lateral positioning and 1,215 patients in supine positioning. Level of agreement was strong across title (κ = 0.872; 95% CI 0.794 to 0.951), abstract (κ = 0.801; 95% CI 0.585 to 1.000), and full-text screening (κ = 1.000). The consensus mean MINORS score of included studies was 17.67 ± 0.58, indicating good to high quality of evidence. Neither patient positioning offered obvious benefits such as fewer complications or shorter operative time.  Furthermore, length of admission, days in ICU or on ventilator, and overall morbidity were not found to be significantly different between positions. Lateral positioning for intramedullary nailing of mid-shaft femur fractures appears to be a safe alternative to the standard supine positioning. There is a lack of both prospective and retrospective comparative studies investigating functional clinical outcomes in the literature.


2019 ◽  
Author(s):  
Jiang Li ◽  
Li Ni ◽  
Yao Pengtao ◽  
Tong Yajing ◽  
Yang Min ◽  
...  

Abstract Introduction: Cancer prevention and screening guidelines are ideally suited to the task of providing high-quality and effective screening in clinical practice. We systematically reviewed cancer screening guidelines for recommended cancer prevention and screening interventions, in order to provide recommendations for development and implementation of high-quality guidelines. Methods: We included cancer screening and prevention recommendations mainly on lung, breast, gastric, liver, colorectal, and prostate from Pubmed, Embase, Web of Science, China Knowledge Resource Integrated Database, Wanfang Data, SinoMed, and then searched in other organizations’ website and database such as the United States Preventive Services Task Force, the American Cancer Society, the American College of Physicians, the National Comprehensive Cancer Network, the National Institute for Health and Care Excellence, European Society for Medical Oncology, and the National Guidelines Clearinghouse until June 30, 2018. An abstraction form to code information according to AGREE II was made and four researchers completed separately. The primary outcome was each recommendation’s quality; the second outcome was benefit-harm “comparability” rating, based on how benefits and harms were presented. Results: There are no high-quality guides in the 19 guides because each domain 3 didn’t reach 60 points, and only 2 guides scored above 50 points. 10 recommendations 9 guidelines were included, year from 2010 to 2018. The majority of guidelines (67%) were supported by a systematic review and that most guidelines had explicit criteria for rating the quality and strength of evidence (64% and 73%, respectively). 7 guidelines clearly mentioned benefits and harms, and 2 only mentioned relevant content. Four of the 55 recommendation statements we reviewed presented the benefits of the intervention in terms of a relative risk reduction (larger number) while presenting the harms in terms of an absolute risk reduction (smaller number). Conclusions:Our findings led us to consider potential contributors to the lack of clarity in guidelines. We recommend the use of “summary of findings” tables, an approach proposed in a series of papers from the GRADE guidelines group, as the best method of summarizing and presenting outcome information.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 961-961
Author(s):  
Sojeong Lee ◽  
Victoria Rizzo

Abstract The visible impact of the SDoHs on health and behavioral health as well as health disparities among minority populations is heightened due to COVID-19. One group about which little is known in relation to SDoHs is the older Korean immigrant population in the U.S. To examine the impact of SDoHs on the health, mental health, and health care utilization, a systematic review of studies focused on SDoHs for this population was conducted. Using multiple indexing terms, databases were searched for articles published in English between January 1, 2011 and December 2020. Articles were included in the search if they examined social determinants of health of older Korean immigrants defined as foreign-born Koreans aged 60 or older who live in the United States regardless of citizenship or legal immigration status. A total of 1090 articles were identified in the search. A review of abstracts for inclusion criteria resulted in 118 articles for review. Seventy-one articles were excluded during the review process. A total of 47 articles met inclusion criteria and were evaluated. The review revealed that SDoHs, including education level, financial resources, access to health insurance, level of acculturation and level of social support, influenced cognitive status, depressive symptoms, health status and quality of life. These findings validate the need for interventions to address the social care needs of older Korean immigrants and can be used to identify the role of social workers in addressing the SDoHs that result in health disparities for older Korean immigrants.


2019 ◽  
Vol 47 (2) ◽  
pp. 249-257 ◽  
Author(s):  
Kelly D. Blake ◽  
Chan Thai ◽  
Angela Falisi ◽  
Wen-Ying Sylvia Chou ◽  
April Oh ◽  
...  

Background. The use of videos for patient and public health education has been widely adopted and well documented in the literature. Aims. To conduct a systematic review of empirical studies that used video-based interventions for cancer prevention and control to document study designs, settings, approaches, targeted cancer sites and behaviors, and outcomes and to identify gaps in research and practice. Method. PubMed, PsychINFO, CINAHL, SCOPUS, and Web of Science were searched for studies published in the 30-year period from 1984 to 2014. Of 1,521 articles identified, duplicates were removed, and titles and abstracts of 779 were examined for eligibility. In all, 315 articles met the inclusion criteria and were coded by three independent coders. Interrater reliability was assessed. Descriptive frequencies and proportions were calculated. Results. Studies evaluating video interventions for cancer prevention and control have increased over time. The majority used randomized controlled trial designs (54%), followed by single-group pre–posttest designs (18%). Most were delivered in health care settings (39%). Detection (30%) and treatment (16%) were the cancer control continuum stages most frequently addressed, with breast cancer (29%) being the most frequently targeted cancer site. The behavior most commonly targeted was screening/early detection (39%). Topics such as caregiving, coping, palliative care, and end of life were rarely addressed. The majority (69%) reported being successful at achieving their stated objectives, though outcomes varied across studies. Conclusions. Video interventions have been widely utilized for cancer prevention and control, with demonstrated successes. Future research should test innovative designs and new delivery platforms and should include underrepresented topics and cancer sites.


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