scholarly journals Synthesis, Spectral Characterization and Antimicrobial Evaluation of New Metal Complexes of Novel Schiff Base Derived from 4,6-dihydroxy-1,3-phenylenediethanone

2021 ◽  
Author(s):  
Yasmin mamdoh hussien Ahmed ◽  
Gehad G. Mohamed
Keyword(s):  
Staphylococcus Aureus ◽  
Schiff Base ◽  
Schiff Base Ligand ◽  
Magnetic Moment ◽  
Magnetic Measurements ◽  
Diffusion Method ◽  
Spectral Studies ◽  
Conductivity Measurements ◽  
Absorption Bands ◽  
Elemental Analyses

Abstract A new tetradentate Schiff base ligand was prepared from condensation of 4,6-dihydroxy-1,3-phenylenediethanone with ethane-1,2-diylbis(oxy)diethanamine. The ligand forms complexes in good yield. The Schiff base and its complexes were characterized by analytical (CHN elemental analyses, solubility, melting point, conductivity) measurements, spectral (IR, UV-vis, 1H NMR and MS) and magnetic measurements. The elemental analyses, Uv-vis spectra, and room temperature magnetic moment data and theoretically through density function theory were used as characterizing techniques in supporting of further interpretation of the complexes structures. The results of elemental analyses, EI-mass and conductivity measurements confirmed the stoichiometry of the ligand and its complexes while the characteristic absorption bands and resonance peaks in IR and NMR spectra confirmed the formation of the ligand frameworks around the metal ions. The octahedral environment for complexes derived from Schiff base ligand have been confirmed on the basis of results of electronic and diffused reflectance spectral studies and magnetic moment measurements. Detailed studies of the thermal properties of the Schiff base ligand and complexes were investigated by thermogravimetric technique. Moreover, the molecular docking into (PDB: 6NE0) was the DNA binding and supports the experimental finding and 6IY0 Crystal structure of conserved hypothetical protein SAV0927 from Staphylococcus aureus subsp. aureus Mu50. The synthesized ligand and its complexes were tested for in vitro antimicrobial activity against Candida albicans, Bacillus subtilis, Aspergillus flavus, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus by using agar-well diffusion method.

scholarly journals Synthesis, Characterization, and Biological Activity of Some Transition Metal Complexes Derived from Novel Hydrazone Azo Schiff Base Ligand

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
C. Anitha ◽  
S. Sumathi ◽  
P. Tharmaraj ◽  
C. D. Sheela
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Schiff Base Ligand ◽  
Second Harmonic ◽  
Biological Activities ◽  
Diffusion Method ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Conductivity Measurements ◽  
Tetrahedral Geometry

A series of metal(II) complexes ML where M = VO(II), Co(II), Ni(II), Cu(II), and Zn(II) have been synthesized from azo Schiff base ligand (N′E)-N′-(5-((4-chlorophenyl)diazenyl)-2-hydroxybenzylidene)-2-hydroxybenzohydrazide and characterized on the basis of elemental analyses, electronic, IR, and 1H NMR spectra, magnetic susceptibility and also by aid of scanning electron microscopy (SEM), X-ray powder diffraction, fluorescence spectral studies, and molar conductivity measurements. Conductivity measurements reveal that the complexes are nonelectrolytes. Spectroscopy and other analytical studies reveal distorted square planar geometry for copper, square-pyramidal geometry for oxovanadium, and tetrahedral geometry for other complexes. Redox behavior of the copper(II) complex has been studied with cyclic voltammetry, and the biological activities of the ligand and metal complexes have been studied against several microorganisms by the well diffusion method. All synthesized compounds can serve as potential photoactive materials as indicated from their characteristic fluorescence properties. The second harmonic generation (SHG) efficiency of the ligand was measured and found to be higher than that of urea and KDP. The SEM image of the copper(II) complex implies that the size of the particles is 50 nm.

Chelates of nickel(II) and copper(II) with tridentate Schiff base formed by the condensation of S-benzyldithiocarbazate with benzoin

1978 ◽  
Vol 56 (15) ◽  
pp. 2000-2002 ◽  
Author(s):  
M. T. H. Tarafder ◽  
M. Akbar Ali
Keyword(s):  
Schiff Base ◽  
Spectral Data ◽  
General Formula ◽  
Schiff Base Ligand ◽  
Nickel Complexes ◽  
Planar Structure ◽  
Spectral Studies ◽  
Square Planar ◽  
Elemental Analyses ◽  
Tridentate Schiff Base

New complexes with the Schiff base ligand derived from S-benzyldithiocarbazate (NH2—NH—CSSCH2C6H5) have been prepared and characterized by elemental analyses, magnetic, conductometric, ir, and electronic spectral studies. The tridentate ONS Schiff base S-benzyl-β-N-(phenyl, phenylhydroxymethyl)methylenedithiocarbazate gave mono-ligand complexes with Ni(II) and Cu(II) having the general formula [MligandX] (M = Ni(II) and Cu(II); X = NO3, Cl, Br, NCS). A proposed square-planar structure for the nickel complexes is supported by magnetic and spectral data. A square-planar structure is also suggested for Cu(II) complexes. The ir results give evidence of the different bondings present in the complexes.

Synthesis, Characterisation and Antimicrobial Activity of Manganese(II), nickel(II), cobalt(II), Copper(II) and Zinc(II) Complexes of a Binucleating Tetradentate Ligand

2002 ◽  
Vol 2002 (11) ◽  
pp. 529-531 ◽  
Author(s):  
Abdou Saad El-Tabl
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Schiff Base Ligand ◽  
Magnetic Moment ◽  
Thermal Analyses ◽  
Antimicrobial Activities ◽  
Esr Spectra ◽  
Tetradentate Ligand ◽  
Tetradentate Schiff Base ◽  
Elemental Analyses

The binucleating, tetradentate Schiff base ligand (H2L) has been synthesised by condensation of bis-(4-aminophenyl)-methane with salicyladehyde. The resulting metal(II) complexes [metal = Mn||, Ni||, Co||, Cu|| and Zn||] have been characterised by elemental analyses, molar conductances, magnetic moment, IR, UV-vis spectra, thermal analyses (DTA and TGA) and ESR spectra. Antimicrobial activities of the ligand and its metal(II) complexes have been tested against different microorganisms. The electrochemical data of complexes (2), (9) and (10) are discussed.

scholarly journals Synthesis and characterization of bioactive binuclear transition metal complexes of Schiff base ligand derived from 4-amino-pyrimidine-2-one, diacetyl and glycine

2014 ◽  
Vol 79 (4) ◽  
pp. 421-433 ◽  
Author(s):  
Abhay Srivastava ◽  
Netra Singh ◽  
Chandra Shriwastaw
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligand ◽  
Magnetic Moment ◽  
Molar Conductance ◽  
Spectral Studies ◽  
Conductance Measurement ◽  
Amino Pyrimidine

A series of novel binuclear transition metal complexes was synthesized by reaction of a Schiff base ligand (1-Methyl-2-(2-oxo-1,2-dihydro-pyrimidin-4-ylimino)-propylideneamino-acetic acid) (LaH) derived from 4-amino-pyrimidine-2-one, diacetyl, glycine and corresponding chloride salt of Cu(II), Ni(II), Co(II) and Zn(II) metals in 1:1 (metal : ligand) molar ratio. The compounds were characterized by elemental analyses, molar conductance measurement, magnetic moment measurement and various spectral studies viz. IR, UV-visible, 1H-NMR, 13C-NMR, EPR and ESI-MS. Molar conductance measurement data revealed non-electrolytic nature of metal complexes. Electronic absorption spectral data, electronic paramagnetic resonance parameters and magnetic moment values revealed an octahedral geometry for binuclear metal complexes. Cyclic voltammetric study of Ni(II) complex shows a couple of one electron anodic responses near 0.70 V and 1.10 V. In vitro biological activity of Schiff base ligand and binuclear complexes has been checked against bacteria (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi) and fungi (Candida albicans and Candida parapsilosis) to assess their antibacterial and antifungal properties.

scholarly journals The template synthesis, spectral characterization and thermal behavior of new binuclear Schiff base complexes derived from N-aminopyrimidine with 2,3-butandion

2007 ◽  
Vol 72 (3) ◽  
pp. 259-264 ◽  
Author(s):  
Mehmet Sönmez ◽  
Memet Şekerci
Keyword(s):  
Schiff Base ◽  
Thermal Behavior ◽  
Thermal Behaviour ◽  
Template Synthesis ◽  
Magnetic Measurements ◽  
Magnetic Moments ◽  
Electronic Spectroscopy ◽  
Schiff Base Complexes ◽  
Conductivity Measurements ◽  
Elemental Analyses

Anew series of two types of acyclic binuclear Schiff base complexes, prepared by the template condensation of N-aminopyrimidine and 2,3-butandion in the presence of Cu(II), Ni(II), Co(II) and Zn(II) in n-BuOH solution, were analyzed and characterized by elemental analyses, IR and electronic spectroscopy, conductivity and magnetic measurements. From the conductivity measurements, it is concluded that the complex of NiII is a 1:1 type of electrolyte. All the complexes have sub-normal magnetic moments in accordance with their binuclear nature. The thermal behaviour of the complexes was studied by thermogravimetry.

scholarly journals One Pot Synthesis of Cu(II) and Ni(II) Peroxo Complexes Containing Schiff Base: Physicochemical, Spectral and Antibacterial Investigations

2020 ◽  
pp. 15-21
Author(s):  
Md. Mahasin Ali ◽  
Md. Nur Amin Bitu ◽  
Md. Saddam Hossain ◽  
Md. Faruk Hossen ◽  
Md. Ali Asraf ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Schiff Base Ligand ◽  
Magnetic Moment ◽  
Pathogenic Bacteria ◽  
Shigella Dysenteriae ◽  
Hydroxyl Group ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Peroxo Complexes

Two new peroxo complexes of Cu(II) and Ni(II) ion containing Schiff base (SB) were synthesized and characterized by TLC, Elemental analyses, conductivity, magnetic moment measurements, UV-Vis. and IR and ESI-MS spectral studies. The Schiff base ligand derived from cinnamaldehyde and o-aminophenol participated in complexation through a single pot reaction. IR spectra showed that the Schiff base ligand coordinated to the metal ion through nitrogen of azomethine group and oxygen of hydroxyl group & peroxo group (O-O). Magnetic moment value coupled with electronic spectral data suggested a square planar geometry for both the complexes. The molar conductance values indicated the non-electrolytic nature of the complexes. Antibacterial activity of the complexes was tested against four pathogenic bacteria, two Gram-positive Staphylococcus aureus & Bacillus cereus and two Gram-negative Escherichia coli & Shigella dysenteriae with Kanamycin (K-30) standard. The result shows that Cu(II) complex exhibited more potential antibacterial activity than the Ni(II) complex against all the tested organisms.

scholarly journals Synthesis, Characterization and Antimicrobial Activity of Cu(II), Co(II) and Ni(II) Complexes with O, N, and S Donor Ligands

2008 ◽  
Vol 5 (3) ◽  
pp. 577-583 ◽  
Author(s):  
Vidyavati Reddy ◽  
Nirdosh Patil ◽  
S. D. Angadi
Keyword(s):  
Schiff Base ◽  
Magnetic Measurements ◽  
Antimicrobial Activities ◽  
Octahedral Geometry ◽  
Donor Ligands ◽  
Azomethine Nitrogen ◽  
Spectral Studies ◽  
Conductivity Measurements ◽  
Schiff Base Ligands ◽  
Plate Method

The complexes of the type ML2[where M = Cu(II), Co(II), and Ni(II)] L = 1-phenyl-1-ene-3-(2-hydroxyphenyl)-prop-2-ene with 3- substituted-5-mercapto-4-amino-1,2,4-triazoles. Schiff base ligands have been prepared by reacting 3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one and 3-phenyl/pyridyl-4-amino-5-mercapto-1,2,4-triazoles in an alcoholic medium. The complexes are non-electrolytes in DMF. The resulting complexes were characterized by elemental analysis, magnetic measurements, conductivity measurements and spectral studies. The Schiff base acts as a tridentate dibasic and coordinating through the deprotonated oxygen, thioenolic sulphur and azomethine nitrogen atoms. It is found that Cu(II), Co(II), and Ni(II) complexes exhibited octahedral geometry. The antimicrobial activities of ligands and its complexes were screened by cup plate method.

scholarly journals Synthesis, DFT and Bio-Potential Activities of Mn(II) and Hg(II) Complexes with Bidentate (E)-N′[(E)-3-Phenylallylidene]benzene-1,2-diamine

2021 ◽  
Vol 33 (6) ◽  
pp. 1222-1228
Author(s):  
R. Selvarani ◽  
S. Balasubramaniyan ◽  
K. Rajasekar ◽  
M. Thairiyaraja ◽  
R. Meenakshi
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Magnetic Moment ◽  
Radical Scavenging ◽  
Molar Conductance ◽  
Diffusion Method ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Dpph Method

A new bidentate Schiff base (E)-N′[(E)-3-phenylallylidene]benzene-1,2-diamine derived from the condensation of o-phenylenediamine and cinnamaldehyde and its Mn(II) and Hg(II) complexes were synthesized and characterized by elemental analysis, molar conductance, magnetic moment, electronic spectra, IR, far-IR and NMR (1H & 13C) spectral studies. The elemental analysis and these metal proposed the metal:ligand stoichiometry and molecular formulae of the metal complexes. The molar conductance and electrochemical property indicates monomeric, neutral nature and redox properties of the metal complexes. The UV-visible spectral study supports the octahedral geometry for Mn(II) complex and square planar geometry for Hg(II) complex and further confirmed by magnetic moment. IR spectral data examined the coordination mode but far-IR is useful to identify the metal-ligand vibrations. The geometry, magnetic property and unsymmetrical nature of these metal complexes corroborated by NMR (1H & 13C) spectra. The DFT of Mn(II) complex studied and the structure optimized by B3LYP/Lan L2DZ using Gaussian 09W. Quantum chemical calculations were done by Mullikan population analysis, HOMO-LUMO and molecular electrostatic potential. The in vitro biological screening effects of the investigated complexes were tested against some bacteria and fungus by agar-well diffusion method. The results indicated that Mn(II) and Hg(II) complexes exhibit potentially active than the Schiff base which was further confirmed by pharmacokinetics study. The antioxidant activity of Schiff base and its Mn(II) complex was examined by radical scavenging DPPH method.

scholarly journals Spectral, Theoretical and Biological Studies of 3-((4-Mercaptophenyl)imino)- 1-phenylindolin-2-one Schiff Base and Its Organotellurium(IV) Complexes

2021 ◽  
Vol 33 (8) ◽  
pp. 1749-1756
Author(s):  
Manish Kumar ◽  
Poonam Jangra Darolia ◽  
Nidhi Antil ◽  
Mahak Dalal ◽  
Jitender Narwal ◽  
...  
Keyword(s):  
Schiff Base ◽  
Schiff Base Ligand ◽  
Molar Conductance ◽  
Spectral Studies ◽  
Receptor Proteins ◽  
E Coli ◽  
Biological Studies ◽  
Elemental Analyses ◽  
Ft Ir ◽  
Bacteria And Fungi

Schiff base ligand (3-((4-mercaptophenyl)imino)-1-phenylindolin-2-one) of 1-phenylindoline-2,3-dione and 4-aminothiophenol was synthesized by refluxing. Organotellurium(IV) complexes of type (RTeCl3.NPhIATP and R2TeCl2.NPhIATP, where R = 4-hydroxyphenyl, 4-methoxyphenyl and 3-methyl-4-hydroxyphenyl, NPhIATP = Schiff base ligand). The ligand and its organotellurium(IV) complexes (9a-f) were characterized by FT-IR, molar conductance, elemental analyses, UV-vis, mass, 1H & 13C NMR spectral studies. Geometry of all the compounds were optimized and octahedral geometry have been proposed for all the tellurium(IV) complexes. Molecular docking was studied to find the binding interactions between ligand (NPhIATP) and receptor proteins: E. coli (3t88) and S. aureus (3ty7). The antimicrobial activity of ligand and its tellurium(IV) complexes have been screened against bacteria and fungi. All the organotellurium(IV) complexes complexes showed good activity to ligand towards different studied microorganisms.

scholarly journals Nematicidal, Fungicidal and Bactericidal Activities of Manganese (II) Complexes with Heterocyclic Sulphonamide Imines

2002 ◽  
Vol 9 (1-2) ◽  
pp. 53-60 ◽  
Author(s):  
Mukta Jain ◽  
Sampat Nehra ◽  
P. C. Trivedi ◽  
R. V. Singh
Keyword(s):  
Molecular Weight ◽  
Nitrogen Atom ◽  
Spectral Data ◽  
High Spin ◽  
Magnetic Measurements ◽  
Spectral Studies ◽  
Conductivity Measurements ◽  
Tetrahedral Geometry ◽  
Elemental Analyses ◽  
Bactericidal Activities

Some manganese(II) complexes derived from different sulphadrugs and heterocyclic ketones have been prepared. These complexes have been characterized on the basis of elemental analyses, molecular weight determinations, conductivity measurements, infrared, ESR and magnetic measurements. The spectral data suggest that the ligands act in a monobasic, bidentate manner coordinating through nitrogen atom. A high spin tetrahedral geometry around this metal has been proposed on the basis of magnetic and spectral studies. The isolated products are coloured solids, soluble in DMSO, DMF and MeOH. All the complexes are monomeric in nature as indicated by their molecular weight determinations and conductivity measurements in dry DMF show them to be non-electrolytes. All the ligands and their corresponding complexes have been screened for their fungicidal, bactericidal and nematicidal activities.

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