scholarly journals Controllable Vesicular Size and Shape in Polymerization-Induced Self-assembly Aided by Aromatic Interactions

2020 ◽  
Author(s):  
Xiao-Fei Xu ◽  
Ren-Man Zhu ◽  
Cai-Yuan Pan ◽  
Ye-Zi You ◽  
Wen-Jian Zhang ◽  
...  
Keyword(s):  
Self Assembly ◽  
Biological Properties ◽  
Vesicle Fusion ◽  
Membrane Tension ◽  
Tubular Structures ◽  
Size And Shape ◽  
Aromatic Interactions ◽  
Polymeric Vesicles ◽  
Solvophobic Interactions ◽  
Structural Regulation

Abstract The size and shape of polymeric vesicles have great impact on their physicochemical and biological properties. Polymerization-induced self-assembly (PISA) is an efficient method to fabricate vesicles. In most PISA-cases, the formation of vesicles is driven by the solvophobic interactions which are lack of versatility on finely structural regulation. Herein, controlling vesicular size and shape is realized in PISA aided by aromatic interactions. Aromatic interactions between the membrane-forming blocks contribute to the augments of membrane tension which lead to the formation of smaller vesicles (as small as 70 nm), but overly enhanced aromatic interactions result in vesicle fusion rather than size decreasing. When the membrane tension is dominated by aromatic interactions and meanwhile high enough to overcome the energetic barriers of fusion, the aromatic interactions drive vesicle fusion in a directional manner to form tubular structures. The precise regulation of vesicular size and shape in PISA would pave the way to fabricate vesicles for a series of size/shape-dependent applications.

scholarly journals Self-assembly of [Au(CN)2]− Complexes with Tomato (Solanum lycopersicum) Steroidal Alkaloid Glycosides to Form Sheet or Tubular Structures

2018 ◽  
Vol 47 (8) ◽  
pp. 1010-1013 ◽  
Author(s):  
Souta Toohara ◽  
Yasuaki Tanaka ◽  
Shinichi Sakurai ◽  
Tsuyoshi Ikeda ◽  
Kazuo Tanaka ◽  
...  
Keyword(s):  
Solanum Lycopersicum ◽  
Self Assembly ◽  
Tubular Structures ◽  
Steroidal Alkaloid

The design of multifunctional nanomaterials through size and shape controlled nanocrystal self-assembly

2021 ◽  
Author(s):  
Christopher B Murray ◽  
Daniel Rosen ◽  
Shengsong Yang ◽  
Yifan Ning ◽  
Cherie R. Kagan ◽  
...  
Keyword(s):  
Self Assembly ◽  
Size And Shape ◽  
Shape Controlled ◽  
Multifunctional Nanomaterials

scholarly journals Fabrication and in vitro evaluation of stable collagen/hyaluronic acid biomimetic multilayer on titanium coatings

2013 ◽  
Vol 10 (84) ◽  
pp. 20130070 ◽  
Author(s):  
Haiyong Ao ◽  
Youtao Xie ◽  
Honglue Tan ◽  
Shengbing Yang ◽  
Kai Li ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Photoelectron Spectroscopy ◽  
Self Assembly ◽  
Human Mesenchymal Stem Cells ◽  
Biological Properties ◽  
Covalent Immobilization ◽  
Layer By Layer ◽  
Titanium Coating ◽  
Assembly Technique

Layer-by-layer (LBL) self-assembly technique has been proved to be a highly effective method to immobilize the main components of the extracellular matrix such as collagen and hyaluronic acid on titanium-based implants and form a polyelectrolyte multilayer (PEM) film by electrostatic interaction. However, the formed PEM film is unstable in the physiological environment and affects the long-time effectiveness of PEM film. In this study, a modified LBL technology has been developed to fabricate a stable collagen/hyaluronic acid (Col/HA) PEM film on titanium coating (TC) by introducing covalent immobilization. Scanning electron microscopy, diffuse reflectance Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy were used to characterize the PEM film. Results of Sirius red staining demonstrated that the chemical stability of PEM film was greatly improved by covalent cross-linking. Cell culture assays further illustrated that the functions of human mesenchymal stem cells, such as attachment, spreading, proliferation and differentiation, were obviously enhanced by the covalently immobilized Col/HA PEM on TCs compared with the absorbed Col/HA PEM. The improved stability and biological properties of the Col/HA PEM covalently immobilized TC may be beneficial to the early osseointegration of the implants.

pH- and Reductant-Responsive Polymeric Vesicles with Robust Membrane-Cross-Linked Structures: In Situ Cross-Linking in Polymerization-Induced Self-Assembly

2019 ◽  
Vol 52 (3) ◽  
pp. 1140-1149 ◽  
Author(s):  
Miao Chen ◽  
Jia-Wei Li ◽  
Wen-Jian Zhang ◽  
Chun-Yan Hong ◽  
Cai-Yuan Pan
Keyword(s):  
Self Assembly ◽  
Cross Linking ◽  
Polymeric Vesicles

Controlling the Physical and Biological Properties of Highly Fluorescent Aqueous Quantum Dots Using Block Copolymers of Different Size and Shape

ACS Nano ◽  
2013 ◽  
Vol 7 (10) ◽  
pp. 9156-9167 ◽  
Author(s):  
Johannes Ostermann ◽  
Jan-Philip Merkl ◽  
Sandra Flessau ◽  
Christopher Wolter ◽  
Andreas Kornowksi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Block Copolymers ◽  
Biological Properties ◽  
Size And Shape ◽  
Aqueous Quantum Dots

scholarly journals Enzyme Immobilization on Maghemite Nanoparticles with Improved Catalytic Activity: An Electrochemical Study for Xanthine

Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1776 ◽  
Author(s):  
Massimiliano Magro ◽  
Davide Baratella ◽  
Andrea Venerando ◽  
Giulia Nalotto ◽  
Caroline R. Basso ◽  
...  
Keyword(s):  
Biological Activity ◽  
Catalytic Activity ◽  
Enzyme Immobilization ◽  
Self Assembly ◽  
Immobilized Enzymes ◽  
Biological Properties ◽  
Oxide Nanoparticles ◽  
Electrochemical Studies ◽  
Maghemite Nanoparticles ◽  
Surface Active

Generally, enzyme immobilization on nanoparticles leads to nano-conjugates presenting partially preserved, or even absent, biological properties. Notwithstanding, recent research demonstrated that the coupling to nanomaterials can improve the activity of immobilized enzymes. Herein, xanthine oxidase (XO) was immobilized by self-assembly on peculiar naked iron oxide nanoparticles (surface active maghemite nanoparticles, SAMNs). The catalytic activity of the nanostructured conjugate (SAMN@XO) was assessed by optical spectroscopy and compared to the parent enzyme. SAMN@XO revealed improved catalytic features with respect to the parent enzyme and was applied for the electrochemical studies of xanthine. The present example supports the nascent knowledge concerning protein conjugation to nanoparticle as a means for the modulation of biological activity.

scholarly journals Nanomedicine: Techniques, Potentials, and Ethical Implications

2006 ◽  
Vol 2006 ◽  
pp. 1-11 ◽  
Author(s):  
Mette Ebbesen ◽  
Thomas G. Jensen
Keyword(s):  
Targeted Drug Delivery ◽  
Self Assembly ◽  
Embryonic Stem ◽  
Biological Properties ◽  
Ethical Considerations ◽  
Human Capabilities ◽  
Ethical Problems ◽  
Ethical Implications ◽  
Physical Chemical ◽  
Cell Versus

Nanotechnology is concerned with materials and systems whose structures and components exhibit novel physical, chemical, and biological properties due to their nanoscale size. This paper focuses on what is known as nanomedicine, referring to the application of nanotechnology to medicine. We consider the use and potentials of emerging nanoscience techniques in medicine such as nanosurgery, tissue engineering, and targeted drug delivery, and we discuss the ethical questions that these techniques raise. The ethical considerations involved in nanomedicine are related to risk assessment in general, somatic-cell versus germline-cell therapy, the enhancement of human capabilities, research into human embryonic stem cells and the toxicity, uncontrolled function and self-assembly of nanoparticles. The ethical considerations associated with the application of nanotechnology to medicine have not been greatly discussed. This paper aims to balance clear ethical discussion and sound science and so provide nanotechnologists and biotechnologists with tools to assess ethical problems in nanomedicine.

Some properties of spherical and rod-shaped semiconductor and metal nanocrystals

2002 ◽  
Vol 74 (9) ◽  
pp. 1675-1692 ◽  
Author(s):  
Christy F. Landes ◽  
Stephan Link ◽  
Mona B. Mohamed ◽  
Babak Nikoobakht ◽  
Mostafa A. El-Sayed
Keyword(s):  
Raman Scattering ◽  
Spherical Particle ◽  
Gold Nanorods ◽  
Self Assembly ◽  
Surrounding Medium ◽  
Cdse Nanocrystals ◽  
Size And Shape ◽  
Metal Nanocrystals ◽  
Enhanced Raman Scattering

In this paper, we summarize our results on the effect of changing size and shape of semiconductor and metallic nanocrystals. The change in size (from 3.5 to 1.1 nm) and shape (from spherical to rod) of CdSe nanocrystals is found to affect both their optical and nonradiative properties. In gold quasi-spherical nanocrystals, results on the dependence of the electron-phonon relaxation of the surrounding medium are presented. For gold nanorods, results and conclusions on the mechanism of their self-assembly are presented. Enhanced Raman scattering on their surfaces is studied and compared with that on spherical particle surfaces.

MOLECULE-UP FABRICATION AND MANIPULATION OF LIPID NANOTUBES

2002 ◽  
Vol 01 (05n06) ◽  
pp. 465-469 ◽  
Author(s):  
TOSHIMI SHIMIZU ◽  
GEORGE JOHN ◽  
AKIHIRO FUKAGAWA ◽  
KOHZO ITO ◽  
HIROSHI FRUSAWA
Keyword(s):  
Optical Tweezers ◽  
Self Assembly ◽  
Flexural Rigidity ◽  
Combinatorial Approach ◽  
Tubular Structures ◽  
Self Assembling ◽  
Degree Of Unsaturation ◽  
Hydrophobic Chain ◽  
Rational Control ◽  
Lipid Nanotube

Self-assembling behavior of both a cardanol-appended glycolipid mixture and the fractionated four components has been examined in aqueous solutions. The cardanyl glucoside mixture differing in the degree of unsaturation in the hydrophobic chain was found to self-assemble in water to form open-ended nanotube structures with 10–15 nm inner diameters. The pure saturated homologue produced twisted helical ribbons through self-assembly, whereas the monoene derivative gave tubular structures. The rational control of helical and tubular morphologies has been achieved by a combinatorial approach through the binary self-assembly of the saturated and monoene derivatives. The flexural rigidity of a single lipid nanotube was first evaluated using optical tweezers manipulation and then compared with that of natural microtubules.

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