scholarly journals Organophosphate Esters in Children and Adolescents in Liuzhou City, China: Concentrations, Exposure Assessment and Predictors

2021 ◽  
Author(s):  
Meng Yu ◽  
Xiang Li ◽  
Bingqing Liu ◽  
Yaping Li ◽  
Ling Liu ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Maternal Education ◽  
Tap Water ◽  
Dietary Factors ◽  
Dermal Absorption ◽  
Indoor Dust ◽  
Organophosphate Esters ◽  
Water Drinking ◽  
Metabolite Concentrations ◽  
Diphenyl Phosphate

Abstract Dermal contact with dust is commonly considered an important pathway of exposure to organophosphate esters (OPEs), but the importance of OPE uptake from diet is unclear. Herein, we used hand wipes to estimate OPE exposure from indoor dust and examined whether urinary OPE metabolite concentrations were influenced by sociodemographic characteristics, OPE amount in hand wipes, and dietary factors. OPEs were measured in urine and hand wipes from 6–18-year old children and adolescents (n=929) in Liuzhou, China. Sociodemographic and dietary factors were obtained from questionnaire. Six OPE metabolites were detected in >70% of the urine samples, and seven OPEs were detected in >50% of the hand wipes. Estimated daily intakes (EDIs) were calculated using urinary OPE metabolites to investigate the total daily intake of OPEs, in which 0.36–10.1% of the total intake was attributed to the exposure from dermal absorption. In multivariate linear regression models, sex, age, and maternal education were significant predictors of urinary OPE metabolite concentrations. Urinary diphenyl phosphate (DPHP) is positively associated with its parent compounds 2-ethylhexyl-diphenyl phosphate (EHDPP) and triphenyl phosphate (TPHP) in hand wipes. High versus low vegetable intake was associated with a 23.7% higher DPHP (95% confidence interval (CI): 0.51%, 52.1%). Barreled water drinking was associated with a 30.4% (95% CI: 11.8%, 52.0%) increase in bis(1-chloro-2-propyl) 1-hydroxy-2-propyl phosphate (BCIPHIPP) compared to tap water drinking. Our results suggested the widespread exposure to OPEs in children and adolescents. In additional to dermal absorption, dietary intake may be an important exposure source of certain OPEs.

scholarly journals Exposure to Phthalate and Organophosphate Esters via Indoor Dust and PM10 Is a Cause of Concern for the Exposed Saudi Population

2021 ◽  
Vol 18 (4) ◽  
pp. 2125
Author(s):  
Nadeem Ali ◽  
Nabil A. Alhakamy ◽  
Iqbal M. I. Ismail ◽  
Ehtisham Nazar ◽  
Ahmed Saleh Summan ◽  
...  
Keyword(s):  
Daily Intake ◽  
Indoor Dust ◽  
Air Conditioner ◽  
Lifetime Cancer Risk ◽  
Organophosphate Esters ◽  
Local Public Health ◽  
Suspended Particulate ◽  
Settled Dust ◽  
Filter Dust ◽  
Ethylhexyl Phthalate

In this study, we measured the occurrence of organophosphate esters (OPEs) and phthalates in the settled dust (floor and air conditioner filter dust) and in suspended particulate matter (PM10) from different microenvironments (households (n = 20), offices (n = 10) and hotels (n = 10)) of Jeddah, Saudi Arabia. Bis (2-Ethylhexyl) phthalate (DEHP) was the major pollutant (contributing >85% of total chemicals burden) in all types of indoor dust with a concentration up to 3,901,500 ng g−1. While dibutyl phthalate (DBP) and DEHP together contributed >70% in PM10 (1900 ng m−3), which indicate PM10 as a significant source of exposure for DBP and DEHP in different Saudi indoor settings. Tris (1-chloro-2-propyl) phosphate (TCPP) was the major OPE in PM10 with a concentration of up to 185 ng m−3 and the occurrence of OPEs in indoor dust varied in studied indoor settings. The estimated daily intake (EDI) of studied chemicals via dust ingestion and inhalation of PM10 was below the reference dose (RfD) of individual chemicals. However, estimated incremental lifetime cancer risk (ILCR) with moderate risk (1.5 × 10−5) for Saudi adults and calculated hazardous index (HI) of >1 for Saudi children from DEHP showed a cause of concern to the local public health.

scholarly journals Relative Validity of an Italian EPIC Food Frequency Questionnaire for Dietary Factors in Children and Adolescents. A Rizzoli Orthopedic Institute Study

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1245
Author(s):  
Inge Huybrechts ◽  
Rossella Miglio ◽  
Lorenza Mistura ◽  
Sara Grioni ◽  
Irene Pozzebon ◽  
...  
Keyword(s):  
Secondary School ◽  
Children And Adolescents ◽  
Food Frequency Questionnaire ◽  
Dietary Factors ◽  
Food Groups ◽  
Food Frequency ◽  
Relative Validity ◽  
Diary Method ◽  
Italian Children ◽  
The Impact

Dietary factors play a major role in the development of non-communicable diseases, however little is known regarding the impact of nutrition on rare diseases like sarcomas. This Rizzoli Orthopedic Institute study aimed to evaluate the relative validity of a Food Frequency Questionnaire (FFQ) to measure the consumption of foods in comparison with a 3-days diary diet in a healthy Italian student population aged between 12 and 17 years. An extended version (including food groups for children) of the semi-quantitative FFQ used in the European Prospective Investigation into Cancer and Nutrition (EPIC) was administered. The validity of the FFQ was assessed by comparing the intakes from the FFQ against the 3-day diary method. 254 Italian subjects were included in the analyses: 128 females; 126 males; 116 from High Secondary School (14–17 years); 138 from Low Secondary School (12–13 years). Mean and median intakes are overall higher in the FFQs than in the food diaries. Spearman correlations adjusted for within-person variability were highest for legumes, vegetables and coffee/tea (>0.5), followed by potatoes, meat, fruits, breakfast cereals, biscuits and candies, and milk/yoghurts (>0.4). Moderate correlations were found for alcoholic drinks, soft drinks, juices, and grains (>0.3). For some food groups, such as fish, potatoes, and bread, correlations tend to become higher when stratifying the analyses for age group. These results demonstrate that the adapted EPIC COS FFQ validated in Italian adults is also appropriate and well understood by Italian children and adolescents.

scholarly journals Occurrence of legacy and alternative plasticizers in indoor dust from various EU countries and implications for human exposure via dust ingestion and dermal absorption

2019 ◽  
Vol 171 ◽  
pp. 204-212 ◽  
Author(s):  
Christina Christia ◽  
Giulia Poma ◽  
Stuart Harrad ◽  
Cynthia A. de Wit ◽  
Ylva Sjostrom ◽  
...  
Keyword(s):  
Human Exposure ◽  
Dermal Absorption ◽  
Indoor Dust ◽  
Eu Countries ◽  
Dust Ingestion

scholarly journals Multipathway risk assessment of trihalomethane exposure in drinking water of Lebanon

2007 ◽  
Vol 5 (4) ◽  
pp. 511-522 ◽  
Author(s):  
Lucy Semerjian ◽  
John Dennis
Keyword(s):  
Cancer Risk ◽  
Tap Water ◽  
Inhalation Exposure ◽  
Dermal Absorption ◽  
Cancer Risks ◽  
Oral Ingestion ◽  
Lifetime Cancer Risk ◽  
Exposed Population ◽  
Total Cancer ◽  
Risk Of Cancer

The toxicological risks and lifetime cancer risks of trihalomethanes through oral ingestion, dermal absorption, and inhalation exposure from tap water in selected regions in Lebanon are estimated. Existing trihalomethane concentrations do not pose any non-carcinogenic and developmental risks in the exposed population via oral ingestion. Among the three pathways, residents have a higher risk of cancer through oral ingestion than through the other two pathways. The lifetime cancer risk through oral ingestion for dibromochloromethane makes the highest contribution to total risks, followed by bromodichloromethane, bromoform, and chloroform. The total multipathway cancer risk analysis suggests that no cancer risks exist during the summer and winter seasons; however, in the spring the total cancer risks exceeds the USEPA acceptable level of 10−6 by a factor of 10.7.

scholarly journals Three-year change in diet quality and associated changes in BMI among schoolchildren living in socio-economically disadvantaged neighbourhoods

2014 ◽  
Vol 112 (2) ◽  
pp. 260-268 ◽  
Author(s):  
Sandrine Lioret ◽  
Sarah A. McNaughton ◽  
Adrian J. Cameron ◽  
David Crawford ◽  
Karen J. Campbell ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diet Quality ◽  
Economically Disadvantaged ◽  
Maternal Education ◽  
Dietary Factors ◽  
Vulnerable Groups ◽  
Overweight Children ◽  
Disadvantaged Women ◽  
Prevention Interventions ◽  
Disadvantaged Neighbourhoods

Findings from research that has assessed the influence of dietary factors on child obesity have been equivocal. In the present study, we aimed to test the hypothesis that a positive change in diet quality is associated with favourable changes in BMI z-scores (zBMI) in schoolchildren from low socio-economic backgrounds and to examine whether this effect is modified by BMI category at baseline. The present study utilised data from a subsample (n 216) of the Resilience for Eating and Activity Despite Inequality study, a longitudinal cohort study with data collected in 2007–8 (T1) and 2010–11 (T2) in socio-economically disadvantaged women and children (5–12 years at T1). Dietary data were collected using a FFQ and diet quality index (DQI) scores derived at both time points. The objective measures of weight, height and physical activity (accelerometers) were included. The other variables were reported in the questionnaires. We examined the association between change in DQI and change in zBMI, using linear regression analyses adjusted for physical activity, screen sedentary behaviour and maternal education level both in the whole sample and in the sample stratified by overweight status at baseline. After accounting for potential covariates, change in diet quality was found to be inversely associated with change in zBMI only in children who were overweight at baseline (P= 0·035), thus supporting the hypothesis that improvement in diet quality is associated with a concurrent improvement in zBMI among already overweight children, but not among those with a normal BMI status. The identification of modifiable behaviours such as diet quality that affect zBMI longitudinally is valuable to inform future weight gain prevention interventions in vulnerable groups.

Concentrations of organophosphate esters and brominated flame retardants in German indoor dust samples

2012 ◽  
Vol 14 (9) ◽  
pp. 2482 ◽  
Author(s):  
Sandra Brommer ◽  
Stuart Harrad ◽  
Nele Van den Eede ◽  
Adrian Covaci
Keyword(s):  
Flame Retardants ◽  
Brominated Flame Retardants ◽  
Indoor Dust ◽  
Organophosphate Esters

scholarly journals Associations of novel 24-h accelerometer-derived metrics with adiposity in children and adolescents

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Jan Dygrýn ◽  
María Medrano ◽  
Pablo Molina-Garcia ◽  
Lukáš Rubín ◽  
Lukáš Jakubec ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Maternal Education ◽  
Paediatric Population ◽  
Overweight And Obesity ◽  
Negatively Associated ◽  
Activity Intensity ◽  
Acceleration Data ◽  
Initial Acceleration ◽  
Visceral Adipose ◽  
Maternal Overweight

Abstract Background Further research is required to explore the associations between 24-h movement behaviours and health outcomes in the paediatric population. Therefore, this study aimed to examine the associations between novel data-driven 24-h activity metrics and adiposity among children and adolescents. Methods The sample included 382 children (8–13 years) and 338 adolescents (14–18 years). The average acceleration (AvAcc) of activity, intensity gradient (IG), and metrics representing the initial acceleration for the most active time periods of the 24-h cycle were calculated from raw acceleration data. Adiposity measures included body mass index z-score, fat mass percentage (FM%), and visceral adipose tissue (VAT). Data analysis was performed using multiple linear regression adjusted for wear time, sex, maternal education level, and maternal overweight and obesity. Results Children demonstrated higher values in all 24-h activity metrics than did adolescents (p < 0.001 for all). For children, the initial acceleration for the most active 2, 5, 15, and 30 min of the 24-h cycle were negatively associated with FM% (p ≤ 0.043 for all) and VAT (p <0.001 for all), respectively. For adolescents, the IG was negatively associated with FM% (p = 0.002) and VAT (p = 0.007). Moreover, initial acceleration for the most active 2, 5, 15, 30, 60, and 120 min were associated with FM% (p ≤ 0.007 for all) and with VAT (p ≤ 0.023 for all). Conclusions The intensity distribution of activity and initial acceleration for the most active 2, 5, 15, 30, 60, and 120 min within the 24-h cycle are beneficial for the prevention of excess adiposity in the paediatric population.

scholarly journals Study on the Changes of the Mineral Contents in Tap-water Drinking with Diverse Teas

2015 ◽  
Vol 37 (9) ◽  
pp. 511-516
Author(s):  
Jeonghee Kim ◽  
Rina Ryoo ◽  
Daesung Song ◽  
Jeongyeop Lee ◽  
Young-Joo Lee
Keyword(s):  
Tap Water ◽  
Mineral Contents ◽  
Water Drinking
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