scholarly journals Rheological Properties of Superparamagnetic Iron Oxide Nanoparticles

2021 ◽  
Vol 8 (1) ◽  
pp. C29-C37
Author(s):  
T. Javanbakht ◽  
S. Laurent ◽  
D. Stanicki ◽  
I. Salzmann
Keyword(s):  
Shear Stress ◽  
Iron Oxide ◽  
Shear Strain ◽  
Rheological Properties ◽  
Superparamagnetic Iron Oxide ◽  
Oxide Nanoparticles ◽  
High Shear ◽  
Shear Rates ◽  
High Shear Rates ◽  
Positively Charged

The present study focuses on the rheological properties of polyethylene glycol (PEG) modified, positively charged, and negatively charged superparamagnetic iron oxide nanoparticles (SPIONs) at different temperatures. We hypothesized that the surface properties of these nanoparticles in the water did not affect their rheological properties. These nanoparticles had not the same surface properties as SPIONs-PEG had not to charge on their surface whereas positively charged and negatively charged ones with amine and carboxyl groups as their surfaces had positive and negative surface charges, respectively. However, their rheological behaviors were not different from each other. The comparative rheological study of SPIONs revealed their pseudo-Newtonian behavior. The viscosity of SPIONs decreased with the increase in temperature. At low shear rates, the shear stress of SPIONs was independent of rate and increased with the increase of rate. Moreover, at high shear rates, the shear stress for PEG-SPIONs was more than those for positively charged and negatively charged SPIONs. These measurements also revealed that at high shear rates, the shear stress of samples decreased with the increase of temperature. The shear stress of samples decreased with the increase of shear strain and the temperature. We also observed that all the samples had the same amount of shear strain at each shear stress, which indicated the exact resistance of SPIONs to deformation. Furthermore, the shear modulus decreased with time for these nanoparticles. These results suggest that these nanoparticles are promising candidates with appropriate properties for fluid processing applications and drug vectors in biomedical applications.

Correlation between physicochemical properties of superparamagnetic iron oxide nanoparticles and their reactivity with hydrogen peroxide

2020 ◽  
Vol 98 (10) ◽  
pp. 601-608
Author(s):  
Taraneh Javanbakht ◽  
Sophie Laurent ◽  
Dimitri Stanicki ◽  
Mathieu Frenette
Keyword(s):  
Hydrogen Peroxide ◽  
Iron Oxide ◽  
Physicochemical Properties ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Surface Modifications ◽  
Oxide Nanoparticles ◽  
Amine Groups ◽  
The Comparative Study ◽  
Positively Charged

The present study focuses on the effects of the physicochemical properties of superparamagnetic PEG-modified, positively charged, and negatively charged iron oxide nanoparticles (SPIONs) on their reactivity with hydrogen peroxide. Our hypothesis was that the reactivity of SPIONs in this reaction would depend on their surface properties. The comparative study of the nanoparticles with DLS and TEM revealed the average sizes of PEG-modified, positively charged, and negatively charged SPIONs. We observed that the reactivity of negatively charged SPIONs with hydrogen peroxide was less than that of positively charged SPIONs and that of these second nanoparticles was less than that of PEG-modified SPIONs. This difference in the reactivity of these SPIONs with hydrogen peroxide was attributed to the presence of carboxyl or amine groups on their surface. However, the values of the rate constants of the reactions of PEG-modified, positively charged, and negatively charged SPIONs with hydrogen peroxide showed that the reaction of negatively charged SPIONs with hydrogen peroxide was more rapid than that of PEG-modified SPIONs and the reaction of these second SPIONs with hydrogen peroxide was more rapid than that of positively charged SPIONs. The surface study of the SPIONs using XPS showed that the high-resolution spectra of these nanoparticles changed after reaction with hydrogen peroxide, which indicates their surface modifications. These investigations can help develop more appropriate nanoparticles with controlled physicochemical properties.

A High Shear Rate Sliding Plate Rheometer for Nonlinear Viscoelasticity

2002 ◽  
Author(s):  
Gholamhossein Sodeifian ◽  
Ali Haghtalab ◽  
Amir Abdollah
Keyword(s):  
Shear Stress ◽  
Viscoelastic Properties ◽  
Nonlinear Viscoelasticity ◽  
Linear Actuator ◽  
High Shear ◽  
Shear Rates ◽  
System A ◽  
Nonlinear Viscoelastic ◽  
High Shear Rates ◽  
Sliding Plate

In most of polymer processings, such as injection molding and extrusion, materials are subjected to high deformations. In order to study nonlinear viscoelastic properties, it is necessary to have an instrument to generate high shear rates. A new sliding plate rheometer incorporating shear stress transducer has been developed. This rheometer has been equipped with a robust servohydraulic linear actuator which can generate shear rates and frequencies up to 900 (1/S) and 500 (Hz) respectively, compared with maximum 500 (1/S) and 100 (Hz), used in latest researches. Using this system, a wider range of nonlinear viscoelasticity can be investigated.

Rheology of Nanofluids in Microchannels

2008 ◽  
Author(s):  
Fre´de´ric Ayela ◽  
Olivier Tillement ◽  
Julien Chevalier
Keyword(s):  
Rheological Properties ◽  
Peclet Number ◽  
High Shear ◽  
Shear Rheology ◽  
Péclet Number ◽  
Shear Rates ◽  
High Shear Rates ◽  
On Chip ◽  
Very High ◽  
High Shear Rheology

Microfluidics is often presented for applications where only microliters sample volumes are available. But the benefits of microchannels do not reduce to a low consumption of fluids. From a physical and mechanical point of view, microfluidics can offer high shear rates combined with low Reynolds number and low viscous heating. It becomes possible to explore high shear rheology on a lab-on-chip. We have micromachined microviscometers to study the rheological properties of nanofluids under very high shear rates conditions. Nanofluids are fluid suspensions of solid nanoparticles. Recent experiments have indicated an anomalous increase in thermal conductivity of these suspensions. But less attention has been payed to the rheological properties of nanofluids. The few results concerning the viscosity of nanofluids exhibit scattered values higher than those of fluid suspensions of microparticles, because of a higher rate of collisions due to Brownian motion and shearing motion which enhance aggregation. These experiments were performed with commercially available rheometers over a limited range of shear rates. Our viscometers on chip are silicon — Pyrex microchannels (H ≈ 10 – 20 μm) equipped with local pressure drop sensors. Nanofluids under test were ethanol-based SiO2 nanoparticles. For particle sizes from 20 nm to 190 nm, and solid volume fractions from 1.4% to 7%, a newtonian behaviour has been observed up to 5.104 s−1. High shear rheology is the only way to reach high Peclet number values with nanoparticles in a laminar flow. It was possible to cover a wide range of Peclet number and to have Pe > 1 with diameter in the tens of nanometers range. Our results have demonstrated that an apparent solid volume fraction φa > φ, due to aggregation, was responsible of the increment of viscosity. More important was the demonstration that the shape of the clusters could be modified and that the ratio φa/φ could be lowered by a very high shear rate. Very high shearing rates in microchannels appear to be a way for nanofluids to converge to a well-defined value of viscosities.

Measurement of the viscosity of supercooled liquids at high shear rates with a Hopkinson torsion bar

1982 ◽  
Vol 381 (1780) ◽  
pp. 195-214 ◽  
Keyword(s):  
Shear Stress ◽  
High Pressures ◽  
Rolling Contact ◽  
Shear Strain Rate ◽  
High Shear ◽  
Shear Rates ◽  
High Shear Rates ◽  
Short Time ◽  
Torsion Bar ◽  
Very High

The Eyring theory of viscous flow suggests that lubricating oils should exhibit shear thinning when the shear stress exceeds about 5 MPa. The results of friction experiments in rolling-contact disc machines where very high pressures are generated in the lubricant film support this prediction, but are open to the criticism that the fluid is subjected to a high pressure for such a short time ( ca . 10 -4 s) that an equilibrium state may not be reached. In the present investigation the appropriate condition of the lubricant is achieved, not by subjecting it to very high pressures but by maintaining it in the supercooled state. The lubricant is thus in a condition of equili­brium and the shear experiments are carried out at atmospheric pressure. The lubricant specimen is retained in a suitably adapted split Hopkinson torsion bar, and at the high rates of shear applied ( ca . 10 4 s -1 ) the shear stress at sufficiently low temperatures can exceed 5 MPa. By this tech­nique the shear pulse is applied for a sufficiently short time ( ca . 10 -3 s) to avoid viscous heating of the sample, which bedevils normal viscometry at high shear rates. Two fluids were tested: polyphenyl ether 5P4E and a mineral oil Shell HVI 650. Nonlinearity in the shear-stress-shear-strain-rate relation was found when the stress exceeded about 3 MPa. The elastic shear modulus G ∞ was also measured, yielding ca . 500 MPa for 5P4E and ca . 50 MPa for HVI 650.These values compare with ca . 1100 MPa and 300 MPa as found by the high-frequency oscillating shear technique at small strains.

Rheological properties of wood polymer composites at high shear rates

2016 ◽  
Vol 51 ◽  
pp. 58-62 ◽  
Author(s):  
Krzysztof Lewandowski ◽  
Kazimierz Piszczek ◽  
Stanisław Zajchowski ◽  
Jacek Mirowski
Keyword(s):  
Rheological Properties ◽  
Polymer Composites ◽  
High Shear ◽  
Shear Rates ◽  
High Shear Rates ◽  
Wood Polymer ◽  
Wood Polymer Composites

Soluble Monomeric Von Willebrand Factor A1A2A3 (R1450E) Mutant Fragment Enhances Shear-Induced Platelet Aggregation and Platelet Adhesion to Fibrin(ogen) Via αIIbβ3 Under High Shear Stress.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 4025-4025
Author(s):  
Miguel A. Cruz ◽  
Katie E. Sowa ◽  
Scott M. Smith
Keyword(s):  
Shear Stress ◽  
Platelet Aggregation ◽  
Von Willebrand Factor ◽  
Platelet Adhesion ◽  
Surface Coverage ◽  
High Shear ◽  
Shear Rates ◽  
High Shear Rates ◽  
Von Willebrand ◽  
Willebrand Factor

Abstract Abstract 4025 Poster Board III-961 Recently, we described that the gain of function mutation R1450E in the A1 domain of von Willebrand factor (VWF) eliminates the formation of catch bond with glycoprotein (GP)Ibα, prolonging the bond lifetimes at low forces. Because those studies were performed with the mutant immobilized on a plastic surface, we further characterize the effect of this mutant on platelet function in solution and under shear stress. Both wild type (WT) and mutant A1A2A3 proteins were expressed in HEK293 cells and purified to homogeneity. The monomeric state of A1A2A3 proteins were assessed by gel filtration chromatography and neither of the proteins had formed dimers or any higher order aggregates. The recombinant A1A2A3 mutant bound spontaneously to GPIbα without the modulator ristocetin with a half-maximal binding observed at 65 ± 8 nM. This apparent dissociation constant was comparable to that of WT (50 ± 10 nM) in the presence of ristocetin. The mutant failed to induce spontaneous platelet aggregation under stirring conditions, and blocked 100% ristocetin-induced platelet agglutination (RIPA) at concentration of 250 nM. At the same concentration, the mutant increased shear-induced platelet aggregation (SIPA) at 500s-1 and 5000s-1 shear rates, reaching 42% and 66%, respectively, while SIPA did not exceed 18% in the presence of WT. The anti-αIIbβ3 antibody 7E3 blocked the effect of the mutant on SIPA. Blood was then incubated with the mutant (250 nM) and perfused over a surface coated with fibrin(ogen) at different shear rates. Blood containing WT resulted in <10% surface coverage by platelets after 1.5 minutes while platelets from blood containing the mutant rapidly bound covering 100% of the fibrin(ogen) surface area at 1500s-1. At shear rate of 2500s-1, surface coverage was 20% for the mutant and 0% for WT fragment. EDTA and antibodies 6D1 (GPIbα) and 10E5 (αIIbβ3) effectively blocked mutant-mediated platelet adhesion and thrombus formation under high shear rates. The addition of ristocetin (0.5 mg/ml) to whole blood prior perfusion reproduced the effect of the mutant. Here, we describe an A1A2A3 mutant that bound spontaneously to GPIbα but affected differently RIPA and SIPA. These results suggest that hydrodynamic forces directly act on the GPIbα-mutant A1A2A3 complex, regulating signaling. In addition, platelet activation induced by the binding of soluble mutant A1A2A3 or plasma VWF results in αIIbβ3-mediated platelet adhesion to fibrin(ogen) under high shear rates. Disclosures: No relevant conflicts of interest to declare.

The Behavior of an Elastohydrodynamic Lubricant at Moderate Pressures and High Shear Rates

1996 ◽  
Vol 118 (1) ◽  
pp. 162-168 ◽  
Author(s):  
Y. Zhang ◽  
K. T. Ramesh
Keyword(s):  
Shear Stress ◽  
Pressure Range ◽  
High Pressures ◽  
Shear Loading ◽  
Thin Layers ◽  
Experimental Results ◽  
High Shear ◽  
Shear Rates ◽  
High Shear Rates ◽  
Wide Range

Knowledge of the behavior of lubricants over a wide range of pressures and shear rates is fundamental to an understanding of elastohydrodynamic (EHD) lubrication. The mechanical properties of elastohydrodynamic lubricants have been measured by a number of researchers under the conditions of low pressures and low shear rates, as well as under high pressures and high shear rates. This paper presents experimental results for the synthetic lubricant 5P4E subjected to moderate pressures (60 MPa to 700 MPa) and high shear rates (105 s−1) using the technique of pressure-shear plate impact. Thin layers (25 μm thick) of the lubricant are confined between two hard elastic plates; the assembly is subjected to impact by a parallel plate in a manner designed to induce both compression and shear loading. For approximately 1 μs the compressed lubricant is subjected to a simple shearing motion; during that time, continuous records of the shear stress and shear rate are obtained using laser interferometry. Three test configurations were used in order to cover the pressure range, and special techniques were developed for preparing the specimen sandwich. The pressure range covered includes both the liquid and glassy states of the lubricant. The results show that a limiting shear stress model is an appropriate model for lubricant behavior under these conditions. The experimental results also show little change in the lubricant shearing behavior across the glass transition.

Sign in / Sign up

Export Citation Format

Share Document