Apolipoprotein A and Apolipoprotein B Levels Along With Standard Lipid Profile in Type II Diabetes Mellitus Patients in a Tertiary Care Centre in Sub Himalayan Region

Patients with Type II diabetes mellitus or the metabolic syndrome have unique dyslipidemia characterized by hypertriglyceridemia; elevated blood levels of apolipoprotein B; small, dense low-density lipoprotein (LDL) cholesterol; and low levels of high-density lipoprotein (HDL) cholesterol. Treatment of dyslipidemia associated with these disorders should focus on correcting the abnormal lipoprotein levels as well as LDL and HDL heterogeneity. Statins and fibrates are useful for treating elevated LDL in patients with and without diabetes or the metabolic syndrome. There are few researches on Apolipoprotein A and Apolipoprotein B, Lipoprotein (a) in India, in comparison to foreign countries. So this study is aimed to evaluate Apo lipoproteins (Apo A1 & Apo B) and Lipoprotein (a) levels along with Lipid profile in Type II Diabetes Mellitus and in patients with Metabolic Syndrome which can be correlated with the risk of cardiovascular disease. Conclusion: Apo lipoprotein A1, Apolipoprotein B and Lipoprotein (a) can be important marker for the risk developing of heart disease. Statistical relationships between LDL and HDL and their respective Apo lipoproteins, Apo B and Apo A-1, in diabetic and metabolic syndrome can be established. Keywords: Lipid profile, Type II Diabetes Mellitus, Apo lipoproteins (Apo A & Apo B), Lipoprotein (a) and Metabolic Syndrome.

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Frequency of Dyslipidemia in Patients with Type-II Diabetes Mellitus

10.53350/pjmhs211582243 ◽

2021 ◽

Vol 15 (8) ◽

pp. 2243-2245

Author(s):

Bilal Rafique Malik ◽

Aneeqa Ilyas ◽

Rehan Anwar

Keyword(s):

Diabetes Mellitus ◽

Lipid Profile ◽

Type Ii Diabetes ◽

Tertiary Care ◽

Type Ii Diabetes Mellitus ◽

Diabetic Patients ◽

Care Hospital ◽

Type Ii ◽

Pathology Laboratory ◽

The Mean

Introduction: Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. Early detection and treatment of dyslipidemia in type-2 diabetes mellitus can prevent risk for atherogenic cardiovascular disorder. Objective: To determine the frequency of dyslipidemia in patients with type II diabetes mellitus presenting in a tertiary care hospital for routine check-up Materials and Methods Study design: Cross sectional study Setting: Department of Medicine (South Medical Ward), Mayo Hospital, Lahore Duration: Six months i.e. 1st July 2020 to 31st December 2020. Data collection procedure: Total 220 patients fulfilling selection criteria were enrolled in the study. Then blood samples were obtained and sent to the pathology laboratory of the hospital for assessment of lipid profile. Reports were assessed and level of cholesterol and triglycerides were noted and dyslipidemia was labeled, if levels were high. All this data was recorded in proforma. Results: In this study, the mean age of patients in this study was 52.71 ± 7.46 years. There were 104 (47.3%) males and 116 (52.7%) females. There were 92 (41.8%) patients of normal BMI, 72 (32.7%) patients were overweight and 56 (25.5%) patients were obese. The mean duration of diabetes was 18.30 ± 3.92 months. Dyslipidemia was diagnosed in 97 (44.09%) patients. Conclusion: Results of this study showed high frequency of dyslipidemia among diabetic patients. Key words: Dyslipidemia, Type II, Diabetes mellitus, Lipid profile

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MICROALBUMINEMIA;

The Professional Medical Journal ◽

10.29309/tpmj/2017.24.03.1618 ◽

2017 ◽

Vol 24 (03) ◽

pp. 478-481

Author(s):

Muhammad Mahboob Alam ◽

Muhammad Akhtar Parvez ◽

Muhammad Murtaza

Keyword(s):

Diabetes Mellitus ◽

Lipid Profile ◽

Type Ii Diabetes ◽

Type Ii Diabetes Mellitus ◽

Diabetic Patients ◽

Type Ii

Objective: to determine the frequency of microalbuminemia in type IIdiabetic patients and to compare lipid profile in type II diabetic patients with and withoutmicroalbuminuria. Settings: Department of Medicine, Allied Hospital, Faisalabad. Durationof study: From: January 2015 to December 2015. Results: In our study, mean age was53.18+9.32 years, 43.90% (n=151) were male and 56.10% (n=193) were females, frequencyof microalbuminuria in type II diabetes mellitus was recorded in 32.56%(n=112). Conclusion:the frequency of microalbuminemia in type II diabetic patients is higher while the frequencyof hypertriglyceridemias, increased LDL-C and decreased HDL-C in Type II diabetic patientsis significantly higher in patients with microalbuminuria when compared them withoutmicroalbuminuria..

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