Prevalence of Thyroid Dysfunction Found in Type II Diabetes Mellitus Patients at Tertiary Care Centre in Jharkhand

2017 ◽  
Vol 5 (1) ◽  
pp. 161
Author(s):  
Dharmendra Kumar ◽  
Sumegha Rana ◽  
Govind Jee Sahay ◽  
Poonam Singh
2020 ◽  
Vol 7 (12) ◽  
pp. 1815
Author(s):  
Mausam Jain ◽  
Pramod R. Jha ◽  
Gaurang Patel

Background: Aim was to study prevalence of thyroid dysfunction in type II diabetes mellitus (T2DM) patients.Methods: The present study was a cross sectional observational study, which focused on cases of diabetes mellitus. Study was conducted in Departments of Medicine, SBKS MI & RC, a tertiary care centre for a period of 6 months. All the patients of T2DM were included. Total of 263 patients were enrolled which involved indoor, outpatient and diabetic clinic attending patients. A detailed history taking, clinical examination and relevant investigations (Hb%, Total count, platelet count, serum creatinine, FBS, PP2BS, HbA1C, S.TSH, F.T3 and F.T4). Appropriate statistical analytics were used and important correlations and conclusions were drawn.Results: A study of thyroid dysfunction (TD) in T2DM patients which included 263 diabetic patients, out of them 67 had thyroid dysfunction. Out of these 67 patients 43 were female and 24 were male. This suggests that female was more prone to thyroid dysfunction than males. Out of 67 TD patients, 42 were above the age of 50 year. So, as the age increases the prevalence of TD also increases thyroid dysfunction also depends on the glycaemic control of the patients. Out of 67 patients 22 patients had>8.0 HbA1C level. In our study we found that as the glycaemic control became poorer the prevalence of TD increase in hypothyroid but not in hyperthyroidism.Conclusions: Following conclusions were drawn from this study TD is more common in female than male, more after the age of 50 year, in T2DM patients. Hypothyroidism is more common with poor glycaemic control and long duration of T2DM patients. But for hyperthyroidism data which we evaluated was not significant and further conclusion bigger study is needed.


2021 ◽  
Vol 54 (2) ◽  
pp. 162-166
Author(s):  
Nosheen Zia ◽  
Sabeen Aftab ◽  
Nauman Ismat Butt ◽  
Fahmina Ashfaq ◽  
Aniqa Anser ◽  
...  

Objectives: To determine the frequency of silent cardiac ischemia in type II diabetes mellitus patients presenting to tertiary care facility. Methodology: This cross-sectional study was conducted from 20th October 2017 to 20th April 2018 at Department of Medicine Jinnah Hospital Lahore. After a detailed history, measurement of height, blood pressure, weight, fasting blood sugar, body mass index of 237 patients were recorded, and electrocardiography (ECG) was done before and after exercise tolerance testing (ETT). Changes in ECG were assessed and person labeled as having silent cardiac ischemia or not depending on the outcome of the ECG. Results: Mean age was 54.9 ± 5.9 (range: 45 – 63) years. There were 144 male patients and 93 female patients The mean duration of type II diabetes mellitus in the study population was 10.0 ± 2.6 (range: 6 – 15) years. The frequency of silent cardiac ischemia was found to be 45.1%. Increasing age, prolonged duration of diabetes mellitus, history of smoking and hypertension, and increased body mass index were significantly related to silent cardiac ischemia (p-value< 0.05). Conclusion: Silent cardiac is quite prevalent in our population that demands urgent efforts to diagnose this condition earlier for better future outcomes.


Author(s):  
Dr. Moumita Hazra ◽  
Dr. Moumita Hazra

Type II diabetes mellitus is a common global hormonal disorder. Inhibition of dipeptidyl peptidase – 4 by dipeptidyl peptidase – 4 inhibitors enhances hormonal activity of incretins, like GLP – 1, GIP, GRP, stimulates insulin release and reduces glucagon secretion, finally producing anti-hyperglycaemic activity in diabetic patients. A clinical pharmacological study of the prevalent prescription patterns of metformin, sitagliptin and gemigliptin among the early moderate grade new type II diabetes mellitus patients in global multi-centre tertiary care hospitals. 100 new early moderate grade type II diabetes mellitus patients, were prescribed oral metformin 500 mg once daily, sitagliptin 25 mg once daily or gemigliptin 25 mg once daily for 3 months, in monotherapy, or in combination therapy, or in a mixed regimen of monotherapy and combination therapy. The safety and efficacy assessments, with blood sugar and HbA1c levels and urine examination, at subsequent intervals and follow-up, were recorded and analysed. The number of prescriptions for each drug was recorded, and the respective prescription rates were statistically analysed in percentages. Metformin was most commonly prescribed (80 prescriptions, 80%), followed by sitagliptin (16 prescriptions, 16%), and gemigliptin (4 prescriptions, 4%). Prescription frequency of metformin was followed by sitagliptin and then by gemigliptin.


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