scholarly journals A prospective observational study to compare the ratio of Pulse oximetric saturation (Spo2)/Fraction of inspired oxygen (Fio2) {S/F ratio} with the ratio of Partial pressure of oxygen(Pao2)/ Fio2 {P/F ratio} among the critically ill children requiring respiratory support in a pediatric intensive care unit

2018 ◽  
Vol 5 (8) ◽  
pp. 80
Author(s):  
Pragathesh Palaniappan ◽  
T Shajin ◽  
Jolly Chandran ◽  
EborJacob James
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Observational Study ◽  
Partial Pressure ◽  
Prospective Observational Study ◽  
Pediatric Intensive Care ◽  
Critically Ill Children ◽  
Partial Pressure Of Oxygen ◽  
Fraction Of Inspired Oxygen ◽  
Inspired Oxygen

scholarly journals Conservative oxygen supplementation versus usual oxygen supplementation among septic medical intensive care units patients: A before-after investigation

2021 ◽  
Vol 104 (2) ◽  
pp. 003685042110169
Author(s):  
Ying Peng ◽  
Xiaoyan Yuan ◽  
Yi Zhang ◽  
Lei Wang
Keyword(s):  
Intensive Care ◽  
Partial Pressure ◽  
Outcome Measures ◽  
Partial Pressure Of Oxygen ◽  
Oxygen Supplementation ◽  
Number Of Patients ◽  
Target Values ◽  
High Fraction ◽  
Fraction Of Inspired Oxygen ◽  
Inspired Oxygen

Patients admitted in the intensive care unit (ICU) are always managed with excessive high fraction of inspired oxygen and have hyperoxia for a significant period of time, which has potential harms. The guidelines for the management of patients in ICUs do not provide the target values for partial pressure of oxygen or arterial oxyhemoglobin saturations. The study was a before-after investigation comparing two time periods in which different oxygenation strategies were applied. Data of oxygen control, outcome measures, and mortality of a total of 273 patients (>18 years) admitted at least for 2 days in ICUs and received treatment for the sepsis were retrospectively collected and analyzed. Patients were received usual oxygen supplementation (targeted partial pressure of oxygen: 150 mmHg; a high fraction of inspired oxygen: 0.4; UOS cohort; n = 142) or conservative oxygen supplementation (targeted partial pressure of oxygen: 70–100 mmHg; a high fraction of inspired oxygen as low as possible; COS cohort; n = 131). Mechanical ventilation-free hours were significantly higher for patients of COS cohort than those of UOS cohort (77.99 ± 21.26 h/patient vs 70.01 ± 23.57 h/patient, p = 0.016). ICUs length of stays of patients of COS cohort was fewer than those of UOS cohort (7.05 ± 2.13 days/patient vs 7.69 ± 2.43 days/patients, p = 0.016). The probability of survival of patients was higher among patients of COS cohort than those of UOS cohort ( p = 0.049). A higher number of patients from UOS cohort needed vasopressors than those from COS cohort (55 vs 35, p = 0.039). Conservative oxygen supplementation to maintain partial pressure of oxygen was improved outcome measures and decreases mortality as compared to that of usual oxygen supplementation. Level of Evidence: III. Technical Efficacy Stage: 4.

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