scholarly journals Ultrasonic Degradation Kinetics and Isomerization of 3- and 4-O-Caffeoylquinic Acid at Various Ph: The Protective Effects of Ascorbic Acid and Epigallocatechin Gallate on Their Stability

2021 ◽  
Author(s):  
Danli Wang ◽  
Jiayuan Liu ◽  
Shaoping Qiu ◽  
Jingjing Wang ◽  
Bingquan Chu ◽  
...  

2021 ◽  
pp. 100147
Author(s):  
Danli Wang ◽  
Jingjing Wang ◽  
Jiachen Sun ◽  
Shaoping Qiu ◽  
Bingquan Chu ◽  
...  




Renal Failure ◽  
2014 ◽  
Vol 37 (2) ◽  
pp. 297-304 ◽  
Author(s):  
Mohamed M. Abdel-Daim ◽  
Ashraf El-Ghoneimy


Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1076
Author(s):  
Guoyi Tang ◽  
Yu Xu ◽  
Cheng Zhang ◽  
Ning Wang ◽  
Huabin Li ◽  
...  

Nonalcoholic fatty liver diseases (NAFLD) represent a set of liver disorders progressing from steatosis to steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma, which induce huge burden to human health. Many pathophysiological factors are considered to influence NAFLD in a parallel pattern, involving insulin resistance, oxidative stress, lipotoxicity, mitochondrial dysfunction, endoplasmic reticulum stress, inflammatory cascades, fibrogenic reaction, etc. However, the underlying mechanisms, including those that induce NAFLD development, have not been fully understood. Specifically, oxidative stress, mainly mediated by excessive accumulation of reactive oxygen species, has participated in the multiple NAFLD-related signaling by serving as an accelerator. Ameliorating oxidative stress and maintaining redox homeostasis may be a promising approach for the management of NAFLD. Green tea is one of the most important dietary resources of natural antioxidants, above which epigallocatechin gallate (EGCG) notably contributes to its antioxidative action. Accumulative evidence from randomized clinical trials, systematic reviews, and meta-analysis has revealed the beneficial functions of green tea and EGCG in preventing and managing NAFLD, with acceptable safety in the patients. Abundant animal and cellular studies have demonstrated that green tea and EGCG may protect against NAFLD initiation and development by alleviating oxidative stress and the related metabolism dysfunction, inflammation, fibrosis, and tumorigenesis. The targeted signaling pathways may include, but are not limited to, NRF2, AMPK, SIRT1, NF-κB, TLR4/MYD88, TGF-β/SMAD, and PI3K/Akt/FoxO1, etc. In this review, we thoroughly discuss the oxidative stress-related mechanisms involved in NAFLD development, as well as summarize the protective effects and underlying mechanisms of green tea and EGCG against NAFLD.



Clinics ◽  
2007 ◽  
Vol 62 (3) ◽  
pp. 315-320 ◽  
Author(s):  
Oscar Haruo Higa ◽  
Edwin Roger Parra ◽  
Alexandre Muxfeldt Ab'Saber ◽  
Cecilia Farhat ◽  
Rita Higa ◽  
...  


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Helena Abramovič ◽  
Blaž Grobin ◽  
Nataša Poklar Ulrih ◽  
Blaž Cigić

Trolox, gallic acid, chlorogenic acid, caffeic acid, catechin, epigallocatechin gallate, and ascorbic acid are antioxidants used as standards for reaction with chromogenic radicals, 2,2-diphenyl-1-picrylhydrazyl (DPPH⋅) and 2,2′-azino-bis-3-ethylbenzotiazolin-6-sulfonic acid (ABTS⋅+), and Folin–Ciocalteu (FC) reagent. The number of exchanged electrons has been analyzed as function of method and solvent. A majority of compounds exchange more electrons in FC assay than in ABTS and DPPH assays. In reaction with chromogenic radicals, the largest number of electrons was exchanged in buffer (pH 7.4) and the lowest reactivity was in methanol (DPPH) and water (ABTS). At physiological pH, the number of exchanged electrons of polyphenols exceeded the number of OH groups, pointing to the important contribution of partially oxidized antioxidants, formed in the course of reaction, to the antioxidant potential. For Trolox, small impact on the number of exchanged electrons was observed, confirming that it is more suitable as a standard compound than the other antioxidants.



2018 ◽  
Vol 83 (12) ◽  
pp. 3019-3026 ◽  
Author(s):  
Ah–Na Kim ◽  
Kyo‐Yeon Lee ◽  
Hyun‐Jin Kim ◽  
Jiyeon Chun ◽  
William L. Kerr ◽  
...  


RSC Advances ◽  
2021 ◽  
Vol 11 (58) ◽  
pp. 36698-36706
Author(s):  
Nirangkush Borah ◽  
Amlan Jyoti Kalita ◽  
Ankur kanti Guha ◽  
Manash R. Das ◽  
Chandan Tamuly

In this work, a colorimetric approach for the detection of ascorbic acid and thyroxine was developed by synthesizing cost-effective silver nanoparticles (AgNPs) decorated with epigallocatechin gallate (EGCG) and CTAB.



Sign in / Sign up

Export Citation Format

Share Document