A New Method of Random Sampling to Reduce the Cost of Regulatory Monitoring

2006 ◽  
Author(s):  
Robert J. Jackson ◽  
David Rosenberg
Keyword(s):  
Random Sampling ◽  
New Method ◽  
The Cost

Selective Sampling and Orientation of Non-Homogeneous Tissues

1968 ◽  
Vol 26 ◽  
pp. 98-99
Author(s):  
C. C. Clawson ◽  
L. W. Anderson ◽  
R. A. Good
Keyword(s):  
Electron Microscopy ◽  
Electron Microscope ◽  
Light Microscopy ◽  
Random Sampling ◽  
New Method ◽  
Microscope Examination ◽  
Small Areas ◽  
Selective Sampling ◽  
Large Numbers ◽  
Specific Orientation

Investigations which require electron microscope examination of a few specific areas of non-homogeneous tissues make random sampling of small blocks an inefficient and unrewarding procedure. Therefore, several investigators have devised methods which allow obtaining sample blocks for electron microscopy from region of tissue previously identified by light microscopy of present here techniques which make possible: 1) sampling tissue for electron microscopy from selected areas previously identified by light microscopy of relatively large pieces of tissue; 2) dehydration and embedding large numbers of individually identified blocks while keeping each one separate; 3) a new method of maintaining specific orientation of blocks during embedding; 4) special light microscopic staining or fluorescent procedures and electron microscopy on immediately adjacent small areas of tissue.

Diplomacy Beyond History: Analytic-Violence, Producer-Centred Research, India

2021 ◽  
pp. 097492842098307
Author(s):  
Deep K. Datta-Ray
Keyword(s):  
New Method ◽  
The West ◽  
History Of ◽  
The Right ◽  
Nuclear Diplomacy ◽  
The Cost ◽  
Insight Into

The history of Indian diplomacy conceptualises diplomacy racially—as invented by the West—and restrictively—to offence. This is ‘analytic-violence’ and it explains the berating of Indians for mimicking diplomacy incorrectly or unthinkingly, and the deleting, dismissing, or denigrating, of diplomatic practices contradicting history’s conception. To relieve history from these offences, a new method is presented, ‘Producer-Centred Research’ (PCR). Initiating with abduction, an insight into a problem—in this case Indian diplomacy’s compromised historicisation—PCR solves it by converting history’s racist rationality into ‘rationalities’. The plurality renders rationality one of many, permitting PCR’s searching for rationalities not as a function of rationality but robust practices explicable in producer’s terms. Doing so is exegesis. It reveals India’s nuclear diplomacy as unique, for being organised by defence, not offence. Moreover, offence’s premise of security as exceeding opponent’s hostility renders it chimerical for such a security is, paradoxically, reliant on expanding arsenals. Additionally, doing so is a response to opponents. This fragments sovereignty and abdicates control for one is dependent on opponent’s choices. Defence, however, does not instigate opponents and so really delivers security by minimising arsenals since offence is eschewed. Doing so is not a response to opponents and so maintains sovereignty and retains control by denying others the right to offense. The cost of defence is courage, for instance, choosing to live in the shadow of nuclear annihilation. Exegesis discloses Balakot as a shift from defence to offence, so to relieve the Bharatiya Janata Party’s (BJP) leadership of having to be courageous. The intensity of the intention to discard courage is apparent in the price the BJP paid. This included equating India with Pakistan, permitting it to escalate the conflict, and so imperiling all humanity in a manner beyond history.

Inferring age from otolith measurements: a review and a new approach

2004 ◽  
Vol 61 (7) ◽  
pp. 1269-1284 ◽  
Author(s):  
RIC Chris Francis ◽  
Steven E Campana
Keyword(s):  
Simulation Experiment ◽  
Cost Benefit Analysis ◽  
Cost Benefit ◽  
New Method ◽  
Population Parameters ◽  
Benefit Analysis ◽  
Mixture Analysis ◽  
New Approach ◽  
Individual Fish ◽  
The Cost

In 1985, Boehlert (Fish. Bull. 83: 103–117) suggested that fish age could be estimated from otolith measurements. Since that time, a number of inferential techniques have been proposed and tested in a range of species. A review of these techniques shows that all are subject to at least one of four types of bias. In addition, they all focus on assigning ages to individual fish, whereas the estimation of population parameters (particularly proportions at age) is usually the goal. We propose a new flexible method of inference based on mixture analysis, which avoids these biases and makes better use of the data. We argue that the most appropriate technique for evaluating the performance of these methods is a cost–benefit analysis that compares the cost of the estimated ages with that of the traditional annulus count method. A simulation experiment is used to illustrate both the new method and the cost–benefit analysis.

scholarly journals Analysis of Effects of Service Quality and Loyalty on Interest Rates of Basketball Athletes in Sahabat Basketball Club Yogyakarta

2020 ◽  
Vol 11 (2) ◽  
pp. 151-160
Author(s):  
Kukuh Hardopo Putro ◽  
Mohd Salleh Aman ◽  
Keyword(s):  
Interest Rates ◽  
Random Sampling ◽  
External Factors ◽  
Major Influence ◽  
Qualitative And Quantitative ◽  
Analysis Techniques ◽  
Using Data ◽  
Internal And External Factors ◽  
The Cost ◽  
Customer Trust

AbstractIn business, especially basketball experience an increased very rapidly, both in terms of quality and quantity in Yogyakarta. Customer as the facilities and services the user pays the cost, much influenced by several internal and external factors. These factors have a major influence on the process of the customer to pay a fee to join and dues in Basketball Clubs. This type of research is descriptive with mixed qualitative and quantitative approach, population in this study is the Athlete Club Basketball “Sahabat” of Yogyakarta, with the number of 20 people, the study sample was determined by random sampling. The technique of collecting data using questionnaires. SPSS.21 using data analysis techniques. While looking at the level of loyalty of respondents to the basketball club Yogyakarta “Sahabat”, 13 of 20 respondents said well (65%) and 7 respondents (35%) had middle loyalty. So from this study showed that customer trust is strongly influenced by the good facilities, appropriate tariffs, staff were nice, the service was very good, and therefore in this study obtained very significant results to customer satisfaction or athletes in the Club Basketball “Sahabat” of Yogyakarta.

scholarly journals r2SCAN-3c: An Efficient “Swiss Army Knife” Composite Electronic-Structure Method

2020 ◽  
Author(s):  
Stefan Grimme ◽  
Andreas Hansen ◽  
Sebastian Ehlert ◽  
Jan-Michael Mewes
Keyword(s):  
Electronic Structure ◽  
Density Functional ◽  
Chemical Space ◽  
Noncovalent Interactions ◽  
New Method ◽  
Basis Set ◽  
Basis Set Superposition Error ◽  
Benchmark Database ◽  
The Cost ◽  
Conformational Energies

The recently proposed second revision of the SCAN meta-GGA density-functional approximation (DFA) {Furness et al., J. Phys. Chem. Lett. 2020, 11, 8208-8215, termed r<sup>2</sup>SCAN} is used to construct an efficient composite electronic-structure method termed r<sup>2</sup>SCAN-3c, expanding the "3c'' series (hybrid: HSE/PBEh-3c, GGA: B97-3c, HF: HF-3c) to themGGA level. To this end, the unaltered r<sup>2</sup>SCAN functional is combined with a tailor-made <br>triple-zeta Gaussian AO-basis as well as with refitted D4 and gCP corrections for London-dispersion and basis-set superposition error. The performance of the new method is evaluated for the GMTKN55 thermochemical database covering large parts of chemical space with about 1500 <br>data points, as well as additional benchmarks for noncovalent interactions, organometallic reactions, lattice energies of organic molecules and ices, as well as for the adsorption on polar salt and non-polar coinage-metal surfaces. These comprehensive tests reveal a spectacular performance and robustness of r<sup>2</sup>SCAN-3c for reaction energies and noncovalent interactions in molecular and periodic systems, as well as outstanding conformational energies, and consistent structures. At just one tenth of the cost, r<sup>2</sup>SCAN-3c provides one of the best results of all semi-local DFT/QZ methods ever tested for the GMTKN55 benchmark database. Specifically for reaction and conformational energies as well as for noncovalent interactions, the new method outperforms hybrid-DFT/QZ approaches, compared to which the computational savings are even larger (factor 100-1000).<br>In relation to other "3c'' methods, r<sup>2</sup>SCAN-3c by far surpasses the accuracy of its predecessor B97-3c at only about twice the cost. The perhaps most relevant remaining systematic deviation of r<sup>2</sup>SCAN-3c is due to self-interaction-error, owing to its mGGA nature. However, SIE is notably reduced compared to other (m)GGAs, as is demonstrated for several examples. After all, this remarkably efficient and robust method is chosen as our new group default, replacing previous low-level DFT and partially even expensive high-level methods in most standard applications for systems with up to several hundreds of atoms.<br><br>

scholarly journals r2SCAN-3c: An Efficient “Swiss Army Knife” Composite Electronic-Structure Method

2020 ◽  
Author(s):  
Stefan Grimme ◽  
Andreas Hansen ◽  
Sebastian Ehlert ◽  
Jan-Michael Mewes
Keyword(s):  
Electronic Structure ◽  
Density Functional ◽  
Chemical Space ◽  
Noncovalent Interactions ◽  
New Method ◽  
Basis Set ◽  
Basis Set Superposition Error ◽  
Benchmark Database ◽  
The Cost ◽  
Conformational Energies

The recently proposed second revision of the SCAN meta-GGA density-functional approximation (DFA) {Furness et al., J. Phys. Chem. Lett. 2020, 11, 8208-8215, termed r<sup>2</sup>SCAN} is used to construct an efficient composite electronic-structure method termed r<sup>2</sup>SCAN-3c, expanding the "3c'' series (hybrid: HSE/PBEh-3c, GGA: B97-3c, HF: HF-3c) to themGGA level. To this end, the unaltered r<sup>2</sup>SCAN functional is combined with a tailor-made <br>triple-zeta Gaussian AO-basis as well as with refitted D4 and gCP corrections for London-dispersion and basis-set superposition error. The performance of the new method is evaluated for the GMTKN55 thermochemical database covering large parts of chemical space with about 1500 <br>data points, as well as additional benchmarks for noncovalent interactions, organometallic reactions, lattice energies of organic molecules and ices, as well as for the adsorption on polar salt and non-polar coinage-metal surfaces. These comprehensive tests reveal a spectacular performance and robustness of r<sup>2</sup>SCAN-3c for reaction energies and noncovalent interactions in molecular and periodic systems, as well as outstanding conformational energies, and consistent structures. At just one tenth of the cost, r<sup>2</sup>SCAN-3c provides one of the best results of all semi-local DFT/QZ methods ever tested for the GMTKN55 benchmark database. Specifically for reaction and conformational energies as well as for noncovalent interactions, the new method outperforms hybrid-DFT/QZ approaches, compared to which the computational savings are even larger (factor 100-1000).<br>In relation to other "3c'' methods, r<sup>2</sup>SCAN-3c by far surpasses the accuracy of its predecessor B97-3c at only about twice the cost. The perhaps most relevant remaining systematic deviation of r<sup>2</sup>SCAN-3c is due to self-interaction-error, owing to its mGGA nature. However, SIE is notably reduced compared to other (m)GGAs, as is demonstrated for several examples. After all, this remarkably efficient and robust method is chosen as our new group default, replacing previous low-level DFT and partially even expensive high-level methods in most standard applications for systems with up to several hundreds of atoms.<br><br>

The Cost–Time Index: A new method for measuring the efficiencies of recruitment-resources in clinical trials

2006 ◽  
Vol 27 (6) ◽  
pp. 494-497 ◽  
Author(s):  
Ken S. Ota ◽  
Leah Friedman ◽  
J. Wesson Ashford ◽  
Beatriz Hernandez ◽  
Allison L. Penner ◽  
...  
Keyword(s):  
Clinical Trials ◽  
New Method ◽  
Time Index ◽  
The Cost

scholarly journals A method for estimating existence of pairwise STM transaction conflicts

2018 ◽  
Vol 232 ◽  
pp. 04037
Author(s):  
Miroslav Popovic ◽  
Branislav Kordic ◽  
Marko Popovic ◽  
Ilija Basicevic
Keyword(s):  
System Performance ◽  
Time Complexity ◽  
Scheduling Algorithms ◽  
False Positives ◽  
New Method ◽  
False Negatives ◽  
Transaction Scheduling ◽  
Data Races ◽  
Cost Of Time ◽  
The Cost

STM transaction schedulers were introduced to improve system performance. However, designing online transaction scheduling algorithms is challenging because at the same time they should: (i) introduce minimal scheduling overhead, (ii) minimize the resulting makespan, and (iii) minimize contention in the resulting schedule. In our previous work we developed the online transaction scheduler architecture and the four scheduling algorithms, named RR, ETLB, AC, and AAC (listed in increasing order of their quality), for scheduling transactions on the Python STM. Both AC and AAC use Bernstein conditions to check for pairwise data races between transactions, at the cost of time complexity that is proportional to the product of the sizes of transaction’s read and write sets, which may be significant. In this paper we propose a method for estimating existence of pairwise transaction conflicts whose time complexity is Θ(1). We validate this method by analysing the resulting transaction schedules for the three benchmark workloads, named RDW, CFW, and WDW. The result of this analysis is positive and encouraging – AAC using the new method produces the same result as when using Bernstein conditions. The limitation of the new method is that it may have false reports, both false negatives and false positives.

scholarly journals Active Learning Approaches for Labeling Text: Review and Assessment of the Performance of Active Learning Approaches

2020 ◽  
Vol 28 (4) ◽  
pp. 532-551
Author(s):  
Blake Miller ◽  
Fridolin Linder ◽  
Walter R. Mebane
Keyword(s):  
Machine Learning ◽  
Active Learning ◽  
Random Sampling ◽  
Supervised Machine Learning ◽  
Learning Approaches ◽  
Simulation Studies ◽  
Text Data ◽  
Passive Learning ◽  
Machine Learning Model ◽  
The Cost

Supervised machine learning methods are increasingly employed in political science. Such models require costly manual labeling of documents. In this paper, we introduce active learning, a framework in which data to be labeled by human coders are not chosen at random but rather targeted in such a way that the required amount of data to train a machine learning model can be minimized. We study the benefits of active learning using text data examples. We perform simulation studies that illustrate conditions where active learning can reduce the cost of labeling text data. We perform these simulations on three corpora that vary in size, document length, and domain. We find that in cases where the document class of interest is not balanced, researchers can label a fraction of the documents one would need using random sampling (or “passive” learning) to achieve equally performing classifiers. We further investigate how varying levels of intercoder reliability affect the active learning procedures and find that even with low reliability, active learning performs more efficiently than does random sampling.

scholarly journals Improving drainage conditions of forest roads using the GIS and forest road simulator

2020 ◽  
Vol 66 (No. 9) ◽  
pp. 361-367
Author(s):  
Mehran Nasiri
Keyword(s):  
Large Scale ◽  
Geometric Design ◽  
New Method ◽  
Small Scale ◽  
Forest Roads ◽  
Forest Road ◽  
Hydrological Conditions ◽  
Large Scale Study ◽  
The Cost

In this study a new method of locating culverts is presented with the composition of achieved discharge from hydrological analysis and simulated forest roads in RoadEng 3D simulator to improve drainage condition. Locating culverts was performed on a small scale (1:20 000, using GIS) and large scale (1:2 000, road geometric design simulator). The small-scale study regarding the achieved discharge from streams shows that the installation of some culverts is not necessary. The large-scale study also showed that the geometric design of forest road has a significant effect on locating culverts and its accuracy. To improve drainage conditions 6 culverts and 2 waterfronts taking into account the geometric design of forest road, hydrological conditions and appropriate intervals (155 m) have been proposed. No installation or lack of accuracy to find the best location of culverts may result in the occurrence of creep and landslide, so the cost of destruction would be several times higher than the cost of technical buildings construction.

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