scholarly journals Influences of Resistance versus Aerobic Exercise on Physiological and Physical Fitness Changes in Previously Inactive Men with Obesity: A Prospective, Single-Blinded Randomized Controlled Trial

2020 ◽  
Vol Volume 13 ◽  
pp. 267-276 ◽  
Author(s):  
Bokun Kim ◽  
Seungyeol Kim
2009 ◽  
Vol 27 (3) ◽  
pp. 344-351 ◽  
Author(s):  
Roanne J. Segal ◽  
Robert D. Reid ◽  
Kerry S. Courneya ◽  
Ronald J. Sigal ◽  
Glen P. Kenny ◽  
...  

Purpose Radiotherapy for prostate cancer (PCa) may cause unfavorable changes in fatigue, quality of life (QOL), and physical fitness. We report results from the Prostate Cancer Radiotherapy and Exercise Versus Normal Treatment study examining the effects of 24 weeks of resistance or aerobic training versus usual care on fatigue, QOL, physical fitness, body composition, prostate-specific antigen, testosterone, hemoglobin, and lipid levels in men with PCa receiving radiotherapy. Patients and Methods Between 2003 and 2006, we conducted a randomized controlled trial in Ottawa, Canada, where 121 PCa patients initiating radiotherapy with or without androgen deprivation therapy were randomly assigned to usual care (n = 41), resistance (n = 40), or aerobic exercise (n = 40) for 24 weeks. Our primary end point was fatigue assessed by the Functional Assessment of Cancer Therapy–Fatigue scale. Results The follow-up assessment rate for our primary end point of fatigue was 92.6%. Median adherence to prescribed exercise was 85.5%. Mixed-model repeated measures analyses indicated both resistance (P =.010) and aerobic exercise (P = .004) mitigated fatigue over the short term. Resistance exercise also produced longer-term improvements (P = .002). Compared with usual care, resistance training improved QOL (P = .015), aerobic fitness (P = .041), upper- (P < .001) and lower-body (P < .001) strength, and triglycerides (P = .036), while preventing an increase in body fat (P = .049). Aerobic training also improved fitness (P = .052). One serious adverse event occurred in the group that performed aerobic exercise. Conclusion In the short term, both resistance and aerobic exercise mitigated fatigue in men with PCa receiving radiotherapy. Resistance exercise generated longer-term improvements and additional benefits for QOL, strength, triglycerides, and body fat.


2020 ◽  
Vol 12 (20) ◽  
pp. 8413
Author(s):  
Sunghwun Kang ◽  
Il Bong Park ◽  
Seung-Taek Lim

The purpose of this study was to investigate changes in the levels of myokines in post- menopausal obese females (PMOF) after regular aerobic and resistance training. A community-based, randomized controlled trial study of 41 PMOF from Buk-gu Community Center in Chuncheon, Gangwon-do, Republic of Korea, was conducted from November 2017 through October 2018. These participants were randomly assigned to an aerobic exercise group (n = 21) or a resistance exercise group (n = 20). The 12-week exercise program was conducted three days a week (Monday, Wednesday, and Friday). Body composition, physical fitness, and myokines were measured at baseline, 6 weeks, and 12 weeks. The two-way within-factor ANOVA revealed group × time interaction for body mass index (BMI, p < 0.05). In the resistance exercise group, muscle endurance (p < 0.001), power (p < 0.01), and agility (p < 0.001) improved significantly at 12 weeks compared to baseline and 6 weeks. In the aerobic exercise group, muscle strength (p < 0.05), flexibility (p < 0.05), muscle endurance (p < 0.001), and agility (p < 0.001) were greater at 12 weeks compared to baseline and 6 weeks. The levels of IL-6 (p < 0.001), IL-15 (p < 0.001), and BDNF (p < 0.001) were greater at 12 weeks compared to baseline and 6 weeks in both exercise groups. Aerobic exercise training and resistance exercise training changed the levels of myokines and improved body composition and physical fitness in PMOF. These findings provide preliminary evidence that PMOF need to exercise or perform physical activity to improve or maintain their levels of myokines and physical fitness.


2021 ◽  
pp. 1-12
Author(s):  
Fang Yu ◽  
David M. Vock ◽  
Lin Zhang ◽  
Dereck Salisbury ◽  
Nathaniel W. Nelson ◽  
...  

Background: Aerobic exercise has shown inconsistent cognitive effects in older adults with Alzheimer’s disease (AD) dementia. Objective: To examine the immediate and longitudinal effects of 6-month cycling on cognition in older adults with AD dementia. Methods: This randomized controlled trial randomized 96 participants (64 to cycling and 32 to stretching for six months) and followed them for another six months. The intervention was supervised, moderate-intensity cycling for 20–50 minutes, 3 times a week for six months. The control was light-intensity stretching. Cognition was assessed at baseline, 3, 6, 9, and 12 months using the AD Assessment Scale-Cognition (ADAS-Cog). Discrete cognitive domains were measured using the AD Uniform Data Set battery. Results: The participants were 77.4±6.8 years old with 15.6±2.9 years of education, and 55%were male. The 6-month change in ADAS-Cog was 1.0±4.6 (cycling) and 0.1±4.1 (stretching), which were both significantly less than the natural 3.2±6.3-point increase observed naturally with disease progression. The 12-month change was 2.4±5.2 (cycling) and 2.2±5.7 (control). ADAS-Cog did not differ between groups at 6 (p = 0.386) and 12 months (p = 0.856). There were no differences in the 12-month rate of change in ADAS-Cog (0.192 versus 0.197, p = 0.967), memory (–0.012 versus –0.019, p = 0.373), executive function (–0.020 versus –0.012, p = 0.383), attention (–0.035 versus –0.033, p = 0.908), or language (–0.028 versus –0.026, p = 0.756). Conclusion: Exercise may reduce decline in global cognition in older adults with mild-to-moderate AD dementia. Aerobic exercise did not show superior cognitive effects to stretching in our pilot trial, possibly due to the lack of power.


BMJ ◽  
2018 ◽  
pp. k851 ◽  
Author(s):  
Chenchen Wang ◽  
Christopher H Schmid ◽  
Roger A Fielding ◽  
William F Harvey ◽  
Kieran F Reid ◽  
...  

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