scholarly journals Cough. The place of herbal medicine in treatment

2021 ◽  
pp. 204-211
Author(s):  
N. I. Lapidus
Keyword(s):  
Leaf Extract ◽  
Mucociliary Clearance ◽  
Respiratory Infections ◽  
Bronchial Tree ◽  
Licorice Root ◽  
Alveolar Cells ◽  
Protective Function ◽  
Cough Reflex ◽  
Drug Of Choice

Cough is one of the auxiliary mechanisms for cleaning the airways from mucus, foreign particles, microorganisms. The physiological cough reflex allows the mechanism of airway cleansing, provided that mucociliary clearance works sufficiently. However, sometimes the cough loses its protective function, becomes persistent, and impairs the quality of life of the patient. In this regard, in the treatment of cough, attention is paid to both secretomotor and secretolytic therapy. Medicinal plants are among the drugs with such properties. Numerous group of drugs containing herbal components has a reflex action, which allows coping most effectively with cough in the initial stages of diseases accompanied by respiratory symptoms. The most common among them and widely used are plantain leaf, coltsfoot leaf, thermopsis herb, ipecacuanha root, marshmallow root, licorice root, anise fruit, thyme (thyme) herb extract, ivy leaf extract. A well-known drug, the active ingredient of which is ivy leaf extract. Its mechanism of action consists in increasing the production of surfactant and increasing the number of β2-adrenoreceptors on the surface of alveolar cells of the bronchial tree, to which ivy active substance α-hederin is attached, which has a bronchospasmodic and expectorant action. Numerous clinical studies have proven a high efficacy and safety of the product based on ivy leaf extract, which allows us to recommend it as the drug of choice for symptomatic cough therapy in both children and adults during acute respiratory infections.

Sinonasal effects of external dacryocystorhinostomy

2021 ◽  
pp. 1-4
Author(s):  
H Eyigor ◽  
E A Cetinkaya ◽  
D T Coban ◽  
G Ozturk ◽  
Ö Erdem
Keyword(s):  
Mucociliary Clearance ◽  
Nasal Symptom ◽  
Ciliary Activity ◽  
Test Results ◽  
Saccharine Test ◽  
Significant Difference ◽  
Symptom Scores ◽  
Endoscopic Score ◽  
External Dacryocystorhinostomy

Abstract Objective External dacryocystorhinostomy is thought to cause mucociliary dysfunction by damaging the mucosa, in turn affecting ciliary activity and mucus quality. This study investigated the effect of external dacryocystorhinostomy on sinonasal function. Methods Patients scheduled for unilateral external dacryocystorhinostomy who underwent endoscopic nasal examination and paranasal sinus computed tomography were included in this study. A saccharine test was performed on the planned surgical side and the mucociliary clearance time was determined. The sinonasal quality of life was measured in all patients, pre-operatively and at six months post-operatively, using the Sino-Nasal Outcome Test-22. The Lund–Kennedy endoscopic score was also determined in all patients, both pre- and post-operatively. Results The study comprised 28 patients (22 females and 6 males). A statistically significant difference was found between the pre- and post-operative saccharine test results (p = 0.006), but not between the pre- and post-operative Sino-Nasal Outcome Test-22 scores (p > 0.05). Conclusion This study is one of only a few to investigate the effect of external dacryocystorhinostomy on sinonasal function. The results showed that external dacryocystorhinostomy impairs mucociliary clearance. The surgical procedure is well tolerated and does not significantly change nasal symptom scores.

scholarly journals Enhancing the Quality of Two Species of Baby Leaves Sprayed with Moringa Leaf Extract as Biostimulant

Agronomy ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1399
Author(s):  
Stefania Toscano ◽  
Antonio Ferrante ◽  
Ferdinando Branca ◽  
Daniela Romano
Keyword(s):  
Leaf Extract ◽  
Foliar Application ◽  
Sugar Content ◽  
Nitrate Content ◽  
Specific Response ◽  
Yield And Quality ◽  
Negative Effect ◽  
Species Specific ◽  
Moringa Oleifera Lam

Natural biostimulants obtained by plants are intensively used nowadays to improve crop yield and quality. The current study aimed to evaluate the effects of leaf extract of moringa (Moringa oleifera Lam.) (MLE) in modifying baby leaf characteristics of two genotypes of Brassica. The trial was started in October 2020 in a greenhouse; a cultivar of kale ‘Cavolo Laciniato Nero di Toscana’ (CL) and a Sicilian landrace of sprouting broccoli ‘Broccoli Nero’ (BN) were used. The plants, after 15, 30 and 40 days from sowing, were treated with MLE, while the control plants (C) with distilled water. Treatment with MLE modified morphological and nutritional value, but with different behavior in the two genotypes. In fact, in BN the treatment reduced the antioxidant activity (2.2-diphenyl-1-picrylhydrazyl (DPPH)) by 54%, while in CL the treatment increased this parameter by 40%. For the phenolic concentration and the sugar content the values recorded were significantly increased by MLE compared to control plants in CL, where in BN a significant reduction was registered. The CL plants treated with MLE showed a significant reduction (−70%) in nitrate content compared to the control plants; a negative effect was, instead, observed in BN, where the plants treated with moringa showed an increase of 60%. Results of this study showed how the foliar application of MLE was effective in improving various nutraceutical parameters, in particular in kale, because it appears to be a species-specific response.

Fifteen-minute consultation: A structured approach to the management of chronic cough in a child

2017 ◽  
Vol 103 (2) ◽  
pp. 65-70 ◽  
Author(s):  
Cherry Alviani ◽  
Gary Ruiz ◽  
Atul Gupta
Keyword(s):  
Chronic Cough ◽  
Respiratory Infections ◽  
School Attendance ◽  
Underlying Disease ◽  
Acute Respiratory Tract Infection ◽  
Healthy Children ◽  
Foreign Materials ◽  
Structured Approach

Coughing is a primary pulmonary defence mechanism that enhances clearance of secretions and particles from the airways and protects against aspiration of foreign materials. Coughing may affect 30% of children at any given time (1). Many are healthy children but some may have serious underlying disease. Childhood cough accounts for a large number of consultations and 80% of families who are referred to a paediatric respiratory clinic for chronic cough have sought medical advice five times or more (2). The majority of childhood coughs are secondary to an acute respiratory tract infection and will improve once the infection resolves, usually within 1 to 3 weeks. With pre-school children who may experience between 6 and 10 respiratory infections a year differentiating acute recurrent cough from chronic cough is key (Table 1). Chronic cough can significantly impact a family’s quality of life, as it affects the child’s sleep, school attendance and play. Parents experience distress and anxiety, worrying that the cough may lead to long-term chest damage or even death (3). This article aims to guide clinicians through the assessment of the child with a chronic cough. It will discuss identifying causes, use of first line investigations, initiating appropriate management and addressing parental anxiety and exacerbating factors (4,5).

scholarly journals Analgesic Drug Use for Carpal Tunnel Syndrome

2019 ◽  
Vol 10 (1) ◽  
pp. 1
Author(s):  
Tamara Audrey Kadarusman ◽  
Hanik Badriyah Hidayati ◽  
Paulus Sugianto
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Work Productivity ◽  
Analgesic Drugs ◽  
Drug Of Choice ◽  
Tunnel Syndrome ◽  
Analgesic Use

AbstractIntroduction: Carpal tunnel syndrome (CTS) is a group of neuropathic symptoms regarding to the compression of median nerve which passing through carpal tunnel. There has been a great number of prevalence of CTS in Indonesia, which leads to decreasing quality of life, lack of work productivity, and increasing health cost. Analgesic treatments have been drug of choice for carpal tunnel syndrome for years. However, the effectiveness of the drug and the risk of adverse effect of drugs have always been an issue for analgesic use. An observational study on profile of analgesic drugs administration for carpal tunnel syndrome patients in Dr. Soetomo General Hospital SurabayaMethod: A descriptive observational retrospective study has been conducted to observe the profile of analgesic drugs administration, including type and dosage of drugs, classification of drugs, drugs administration route, early and advanced type of analgesics, and duration of analgesic administration. Sociodemographic data and clinical characteristics (main symptoms) of carpal tunnel syndrome patients are also included in this study.Results: Out of 202 subjects of this study, most patients are women (84,16%), the group age of 50-59 to years old, and the most frequent job is household wife (43,56%). The most common analgesic drugs used for carpal tunnel syndrome patients is 50 mg sodium diclofenac for 78 patients (38.61%). All of those subjects are administered with oral analgesic (100%). 185 patients (91.59%) are administered with analgesic combinations. The duration of analgesic usage are 7 days as an early analgesic in 82 patients (40.59%).Conclusion: CTS is a syndrome due to median nerve compression of the hand, Women, household wife, and age of 50-59 years old are found to be vulnerable to this syndrome. Analgesic drugs mostly used is 50 mg natrium diclofenac, orally, combined, with the period of 7 days for early medication

scholarly journals Quality assessment of praziquantel tablets sold in medicine stores in Kano Metropolis

2018 ◽  
Vol 11 (1) ◽  
pp. 208-210
Author(s):  
M.A. Gadanya ◽  
K.A. Ahmad
Keyword(s):  
Standard Dose ◽  
Poor Quality ◽  
Regulatory Agencies ◽  
Cure Rate ◽  
Quality Cost ◽  
Expiry Date ◽  
Drug Of Choice ◽  
Praziquantel Treatment ◽  
Control Programmes

The efficacy, availability, tolerable side effects and relative affordability of praziquantel makes it the drug of choice in the treatment and various control programmes of schistosomiasis in the endemic areas with excellent outcomes. However, there are reports of low cure rate with praziquantel observed by clinicians with various speculations on the likely causes. This study explored poor drug quality as a possible cause of praziquantel treatment failure in schistosomiasis. On the spot sampling of twelve different samples of praziquantel tablets from various patent medicine shops in Kano metropolis were assayed for active ingredient using British Pharmacopeia methods. Only 6 out of 12 (50%) of the praziquantel tablets studied were found to be acceptable of quality. Cost and number of months before expiry date were not found to be significantly associated with the quality of the drug. Poor quality praziquantel currently in the market may possibly explain failure of standard dose of the drug in the treatment of schistosomiasis. Therefore, it is recommended that additional vigilance by regulatory agencies is required to ensure quality drugs in the market.Keywords: Efficacy, Kano, praziquantel, quality, schistosomiasis

scholarly journals Analysis of the interventions adopted due to the COVID-19 on ARI morbility for Colombia

2020 ◽  
Author(s):  
Alvaro Quijano-Angarita ◽  
Oscar Espinosa ◽  
Marcela M Mercado-Reyes ◽  
Diana Walteros ◽  
Diana Carolina Malo
Keyword(s):  
Respiratory Infections ◽  
Age Groups ◽  
World Health ◽  
Health Concern ◽  
Surveillance Systems ◽  
Highly Correlated ◽  
Health Organization ◽  
Tract Infections ◽  
Official Declaration

Acute Respiratory Infections are among the leading causes of death globally, particularly in developing countries, and are highly correlated with the quality of health and surveillance systems and effective early interventions in high-risk age groups. According to the World Health Organization, about four million people die each year from mostly preventable respiratory tract infections, making it a public health concern. The official declaration of a pandemic in March 2020 due to the Sars-CoV-2 virus coincided with the influenza season in Colombia and with environmental alerts about low air quality that increase its incidence. The objective of this document is the application of a flexible model for the identification of the pattern and monitoring of ARI morbility for Colombia by age group that shows atypical patterns in the reported series for 5 departments and that coincide with the decisions implemented to contain the COVID-19

The Use of Children's Medical Records to Predict the Risk of Asthma Attack

1995 ◽  
Vol 40 (5) ◽  
pp. 138-140 ◽  
Author(s):  
R.G. Neville ◽  
F.P. Bryce ◽  
R.A. Clark ◽  
I K Crombie
Keyword(s):  
Childhood Asthma ◽  
Medical Records ◽  
Respiratory Symptoms ◽  
Respiratory Infections ◽  
Large Data ◽  
Respiratory Morbidity ◽  
Asthma Attack ◽  
One Year ◽  
Subsequent Risk

Using a large data base of respiratory morbidity in children the opportunity arose to explore the link between what was written in general practice case records and the subsequent risk of a child developing an asthma attack or hospital admission due to asthma. Children with five or more consultations in one year for respiratory symptoms had a 33% risk of experiencing an asthma attack or 7.1% risk of admission in the following year. Twenty seven percent of children who received antibiotics for “respiratory infections” subsequently had an asthma attack. The potential exists to review past and present symptoms and thus attempt to predict future morbidity. Childhood asthma is an example where the quality of care offered by general practitioners could be improved if a precise estimate of risk could be used to modify clinical management.

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