scholarly journals The validity of topical drug therapy for otitis media with effusion

2021 ◽  
pp. 80-84
Author(s):  
S. V. Morozova ◽  
K. V. Eremeeva ◽  
W. H.A. Suaifan

Otitis media with effusion is difficult to diagnose, since the course of the disease is mostly asymptomatic, while the initial stage of the disease is very similar to Eustachiitis or the pre-perforative stage of acute otitis media. At this stage, dysfunction of the auditory tube and negative pressure in the tympanic cavity creates the conditions for the production of transudate, which clinically, in addition to hearing loss, is accompanied by soreness, a feeling of congestion, pressure, fluid transfusion in the ear. When conducting local medical procedures, they are primarily guided by the condition of the mucous membrane of the eustachian tube, nasopharynx and nasal cavity, but changes in the eardrum are no less important. Thus, the use of topical analgesics with an anti-inflammatory effect becomes no less relevant in the treatment.A literature review was carried out with an analysis of scientific research data on the use of a topical combination drug that has a local anesthetic and anti-inflammatory effect in the treatment of diseases of the external and middle ear.Analysis of the literature showed that the use of lidocaine-phenazone-containing drops promotes rapid regression of the inflammation in the external auditory canal and the tympanic membrane, as well as relieving of pain. It can be used both in children (including newborns) and in adults who are suffering from otitis media but with intact tympanic membrane, including otitis media with effusion.Combined topical drugs containing lidocaine-phenazone demonstrate efficacy and safety in the treatment of catarrhal and otitis media with effusion in all age groups.

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Christina T. Ryborg ◽  
Jens Søndergaard ◽  
Jørgen Lous ◽  
Anders Munck ◽  
Pia V. Larsen ◽  
...  

Background. Acute otitis media (AOM) is often treated with antibiotics. However, initial observation is recommended. Denmark has a low use of antibiotics compared with other countries, but the total use of antibiotics has increased by 32% during the last decade, and it is important to know whether general practitioners (GPs) prescribe antibiotics according to guidelines. Objective. The aim of the study was to analyse associations between GPs' antibiotic prescribing for AOM and symptoms, diagnoses, and characteristics of children. Methods. A cohort study where GPs consecutively included 954 children between 0 and 7 years old with a new ear symptom was carried out. The GPs registered symptoms, results of otoscopy and tympanometry, together with diagnosis and treatment. Results. Fever with and without earache was statistically associated with prescribing antibiotics, and it applies to both children up to two years of age (OR: 5.89 (confidence interval (CI): 2.62–13.21) and OR: 8.13 (CI: 4.61–14.32)) and children older than two years of age (OR: 4.59 (CI: 2.55–8.25) and OR: 19.45 (CI: 6.38–59.24)). A red tympanic membrane was statistically associated with the prescribing antibiotics in both age groups (0–2 years: OR: 4.73 (CI: 2.52–8.86) and >2–7 years: OR: 3.76 (CI: 2.13–6.64)). A flat tympanometry curve was only statistically associated with prescribing antibiotics in the oldest children (OR: 2.42 (CI: 1.17–5.00)). Conclusion. This study indicates that GPs to a large degree prescribe antibiotics appropriately according to guidelines.


2015 ◽  
Vol 30 (2) ◽  
pp. 50-55
Author(s):  
Jay Pee M. Amable ◽  
Lily L. Sia-Vargas

Objective: To fabricate a single instrument that can be used to perform myringotomy and insert a pressure equalizing tube at almost the same time.   Methods: Study Design: Surgical Instrumentation Setting: Tertiary Private Hospital Subject: A chicken egg membrane was used as a tympanic membrane model   Result: The fabricated instrument was able to perforate the egg membrane and apply the modified polyethylene pressure equalizing tube in less than one minute without complications.   Conclusion: The prototype applicator can facilitate myringotomy and pressure equalizing (PE) tube insertion at only a fraction of the time it usually takes to do the standard myringotomy and subsequent ventilating tube insertion.   Keywords: Myringotomy, pressure equalizing tube, ventilating tube, acute otitis media, otitis media with effusion, polyethylene tube


PEDIATRICS ◽  
1983 ◽  
Vol 71 (4) ◽  
pp. 639-652
Author(s):  
Charles D. Bluestone ◽  
Jerome O. Klein ◽  
Jack L. Paradise ◽  
Heinz Eichenwald ◽  
Fred H. Bess ◽  
...  

GOALS, DEFINITIONS, AND CLASSIFICATION OF OTITIS MEDIA —Charles D. Bluestone, MD The goal of this Workshop was to assess current knowledge concerning the effects of otitis media on the child. Experts in pediatrics, infectious disease, otolaryngology, audiology, speech, linguistics, and psychology met in Chicago on Aug 25, 1982 to participate in this Workshop. A summary of the discussions is presented here. Otitis media is broadly defined as an inflammation of the middle ear without reference to etiology or pathogenesis.1 Otitis media with effusion is an inflammation of the middle ear in which a collection of liquid (i.e., middle ear effusion) is present in the middle ear space (no perforation of the tympanic membrane is present). Atelectasis of the tympanic membrane, which may or may not be associated with otitis media, is defined as either collapse or retraction of the tympanic membrane. Acute otitis media implies a rapid and short onset of signs and symptoms lasting approximately 3 weeks. From 3 weeks to 3 months, the process may be resolving or subacute. If middle ear effusion persists beyond 3 months, the condition is classified as chronic otitis media with effusion. Many terms have been used for acute otitis media, such as "suppurative," "purulent," or "bacterial" otitis media; however, a "serous" effusion may also have an acute onset. Otitis media with effusion unaccompanied by signs and symptoms of acute inflammation has also had a plethora of other names: "serous," "secretory," "nonsuppurative," and "glue ear" have been the most commonly used. EPIDEMIOLOGY AND NATURAL HISTORY OF OTITIS MEDIA


1992 ◽  
Vol 13 (1) ◽  
pp. 23-24
Author(s):  
Gerald B. Healy

Otitis media with effusion (OME) offers the primary care physician both a diagnostic and a therapeutic challenge. The tympanic membrane of a child frequently is difficult to assess, especially in the uncooperative patient whose ear canal is partially occluded by cerumen. However, if the ear canal can be cleared to allow an unobscured view of the tympanic membrane, then pneumatic otoscopy and tympanometry can be extremely valuable in both the diagnosis and follow-up after initiation of treatment. Patient Groups The pediatrician usually is faced with two groups of patients in this disease process. The first group includes the young child who has recurrent episodes of acute otitis media. Frequently, affected patients can be subdivided into those who clear their middle ear space of fluid between episodes and those who do not. The second group consists of children who have asymptomatic chronic effusion, usually leading to persistent hearing loss. These children tend to be slightly older but are no less troublesome for the clinician. Treatment Controlled clinical trials have been extremely important in providing information about both of these groups. These studies have shown that chemoprophylaxis is extremely useful in managing the patient who has recurring acute suppurative episodes not complicated by persistent effusion during the interval periods.


Author(s):  
Ashutosh S. Kumar ◽  
Gundappa D. Mahajan ◽  
James Thomas ◽  
Tejal A. Sonar

<p class="abstract"><strong>Background:</strong> Otitis media with effusion (OME) is defined as the presence of a middle ear effusion in the absence of infection. Fluid in the middle ear is associated most commonly with a conductive hearing loss and an increased risk of acute middle ear infection. It can have an impact on quality of life. The objective of our study was to assess symptomatology of OME, study complications following tympanostomy tube insertion in OME and to highlight the age, sex distribution of otitis media with effusion.</p><p class="abstract"><strong>Methods:</strong> This prospective study was conducted in Department of Otorhinolaryngology, Dr. D. Y. Patil Medical College and Hospital, Pimpri, Pune from October 2017 to March 2019. 50 ears of patients aged between 6 to 50 years with OME were included in the study. All the patients were observed for symptomatology and postoperative complications who underwent Tympanostomy tube insertion.  </p><p class="abstract"><strong>Results:</strong> OME is commoner in children and adolescents with no gender preponderance. The most common otoscopic findings pre-operatively included dull lustreless amber colored tympanic membrane in 56% (n=28), Retracted Tympanic Membrane and for shortened handle of malleus in 28% (n=14), air bubbles were seen in 12% (n=6) whereas fluid level was seen in 4% (n=2). Common complications post operatively included myringosclerosis and tympanic membrane atelectasis seen in 10% and 6% respectively.</p><p class="abstract"><strong>Conclusions:</strong> Tympanostomy tube insertion is one of the ideal treatments in management of otitis media with effusion, most commonly affecting younger age groups, with fewer complications, which can lead to a better quality of life.</p>


Author(s):  
Vivek K. Pathak ◽  
Pradeepti Nayak ◽  
Sonali Tyagi ◽  
Rohit Chaudhary

<p class="abstract"><strong>Background:</strong> It has been defined as a permanent abnormality of pars tensa or flaccida, as a result of acute otitis media, negative middle ear pressure or otitis media with effusion. It manifests clinically as ear discharge and decreased hearing and may lead to numerous changes in the tympanic membrane, middle ear cleft, and mastoid air cell system. It has been classified into two types: mucosal and squamosal types. Chronic otitis media (COM) is a very common condition in developing countries in both adult and paediatric age groups. This study has been conducted to determine the outcome and graft uptake of tragal perichondrium in type 1 tympanoplasty.</p><p class="abstract"><strong>Methods:</strong> The prospective analytical study was conducted department of otorhinolaryngology, School of Medical Sciences and Research, Greater Noida, Uttar Pradesh, India over a period of 12months from 01 January 2019 to 31 December 2019. 30 patients according to inclusion criterion underwent tympanolpasty using tragal perichondrium were included in study. The data obtained was analyzed using statistical package for the social sciences (SPSS), version 21.0. P value less than 0.05 was taken as statically significant.  </p><p class="abstract"><strong>Results:</strong> Preoperative mean hearing loss was 38.45±7.01 dB, mean air bone gap was 20.20±3.75 dB, and postoperative air bone gap was reduced to an average of 10.86±3.82 dB. 8.51 dB of hearing gain was achieved and an air bone gap réduction of 8.51 dB was observed.</p><p class="abstract"><strong>Conclusions:</strong> Our study concluded tragal perichondrium is a suitable graft material is n mucosal type of COM.</p>


2018 ◽  
Vol 23 (01) ◽  
pp. 036-040
Author(s):  
Emine Demir ◽  
Sevgi Topal ◽  
Gorkem Atsal ◽  
Mehmet Erdil ◽  
Zerrin Coskun ◽  
...  

Introduction the otological evaluation is highly significant in those branches of medicine in which the general evaluation of the patient is conducted by general practitioners and pediatricians. Objectives To investigate the otologic findings and their incidences in the sample, which consisted of patients who presented to the pediatric outpatient clinic with non-otologic complaints. Methods Patients, aged between 2 and 16 years, who had neither otorhinolaryngological complaints nor history of surgery by the otolaryngology (ear, nose and throat, ENT) department were included in the present study. The findings detected in the external auditory system and in the tympanic membranes as well as the otorhinolaryngologists' otologic examination findings of the referred patients were recorded from the files of each patient along with the applied medical and surgical treatments, and diagnostic investigations. Results Of a total of 973 patients evaluated, 129 (13.2%) were referred to the ENT outpatient clinic due to any otologic pathology. In the otorhinolaryngological examinations, false positivity was detected in 12 (1.2%) patients, and pathological findings were detected in 117 (12%) patients who received the following diagnoses: 68 (6.9%) had otitis media with effusion(OME); 37 (3.8%) had cerumen impactions; 8 (0.8%) had acute otitis media (AOM); 2 (0.2%) had ticks in the external auditory canal; 2 (0.2%) had a retraction pocket in tympanic membrane; 1 (0.1%) had unilateral central dry perforation of the tympanic membrane; and 1(0.1%) had congenital cholesteatoma. Conclusion Any complications and sequelae that may develop due to any pathologies and predominantly infections can be prevented by an early diagnosis, which can be made by means of a simple examination, performed merely with an otoscope. Pediatricians and general practitioners should be in close contact with otorhinolaryngologists regarding the pathologies they identify.


2004 ◽  
Vol 118 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Bülent Aktan ◽  
Cemal Gundogdu ◽  
Harun Ucuncu ◽  
Bunyami Unal ◽  
Yavuz Sütbeyaz ◽  
...  

In this study, the anti-inflammatory effect of erythromycin was investigated in a model of histamine-induced otitis media with effusion (OME). OME was induced in guinea pigs by the transtympanic injection of histamine solution into the middle-ear cavity. Guinea pigs were randomly assigned to one of three groups: control, erythromycin treatment, or methylprednisolone treatment. After histamine injection, the animals were treated with intraperitoneal medication for five days consecutively. Afterwards, the animals were sacrificed and the temporal bones were removed. The samples were examined stereologically.In the erythromycin-treated group, it was observed that neutrophil infiltration was significantly inhibited when compared to the control group. This result shows that erythromycin may produce a significant anti-inflammatory effect in this model of OME.


2003 ◽  
Vol 112 (6) ◽  
pp. 558-566 ◽  
Author(s):  
Per Olof Eriksson ◽  
Cecilia Mattsson ◽  
Sten Hellström

The early inflammatory changes in the tympanic membrane were explored in 2 rat models. Acute otitis media was induced by instillation of Streptococcus pneumoniae type 3 into the middle ear cavity, and otitis media with effusion was induced by blockage of the eustachian tube. Otomicroscopic examination was performed before the rats were painlessly sacrificed at 3, 6, 9, 12, 18, 24, or 48 hours after initiation of the otitis media conditions. The tympanic membrane was studied by light and electron microscopy. Both acute otitis media and otitis media with effusion caused early inflammatory changes of the tympanic membrane, and the pars flaccida was the portion that reacted first. The inflammatory alterations were most pronounced in the acute otitis media model. The course of inflammation showed a bimodal pattern with an early deposition of a filamentous material with a band pattern, typical of fibrin. Despite a fluid-filled middle ear cavity, the inflammatory changes in the otitis media with effusion model were moderate, as was consistent with the clinical appearance of the tympanic membrane.


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