scholarly journals Case report of leiomyosarcoma, a very rare type of urinary bladder tumour

2017 ◽  
Vol 73 (7) ◽  
pp. 439-444
Author(s):  
Aleksandra Sobczyńska-Rak ◽  
Izabela Polkowska ◽  
Beata Żylińska ◽  
Anna Śmiech ◽  
Anna Łojszczyk- Szczepanik
Keyword(s):  
Urinary Bladder ◽  
Bladder Tumour ◽  
Transitional Cell ◽  
Diagnostic Techniques ◽  
Urinary Flow ◽  
Rare Type ◽  
Regional Lymph Nodes ◽  
Abdominal Organs ◽  
Urinary Bladder Tumour ◽  
Bladder Tumours

Urinary bladder tumours account for approximately 1% of all tumours in dogs. The majority of them are epithelial in origin and malignant. Transitional cell carcinoma (TCC) is the most commonly diagnosed tumour of the urinary bladder. Malignant mesenchymal tumours in humans and animals are far less frequent than epithelial ones. Malignant mesenchymal urinary bladder tumours are represented by rabdomyosarcoma (RMS) and leiomyosarcoma (LMS). LMS occurs in older dogs, aged 7 - 12 years, and originates from the urinary bladder trigone and urethra, thus disturbing the urinary flow. LMSs are usually invasive, with a tendency to metastasize rapidly to the regional lymph nodes or abdominal organs, such as the liver, pancreas, kidneys, intestines and omentum. The aim of this report is to describe the clinical presentation, diagnostic approach and surgical treatment of the urinary bladder leiomyosarcoma that occurred in a Bernese Mountain Dog. The paper also highlights the latest diagnostic techniques for urinary bladder tumour detection, general rules of surgical resection and chemotherapy.

scholarly journals Urothelial Tumours of the Urinary Bladder: A Histopathological Study of Cystoscopic Biopsies

2013 ◽  
Vol 52 (191) ◽  
Author(s):  
Sujan Vaidya ◽  
Mamata Lakhey ◽  
Sabira KC ◽  
Suspana Hirachand
Keyword(s):  
Urinary Bladder ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Bladder Tumour ◽  
Transitional Cell ◽  
Histopathological Study ◽  
Low Grade ◽  
High Grade ◽  
Urothelial Tumours ◽  
Bladder Tumours

Introduction: Bladder tumours constitute one of the most common urological conditions. Urothelial(transitional cell) carcinoma accounts for 90% of all primary tumours of the bladder. These tumoursare an important cause of morbidity and mortality. The objective of this study was to present thehistopathological patterns of urothelial tumours and to determine the grade and stage of thesetumours.Methods: This is a 3 year descriptive study of urothelial tumours carried out in the Departmentof Pathology, Patan Academy of Health Sciences (PAHS), Lalitpur, Nepal. Data of all cystoscopicbiopsies collected during this period were analyzed.Results: Of the 83 urinary bladder tumours, 81 (97.59%) cases were urothelial (transitional cell)tumours. Transitional cell carcinoma (TCC) was the most common bladder tumour which was seenin 67 (80.72%) cases. Thirty two (47.76%) cases of TCC were low grade while 35 (52.24%) were highgrade. Forty three (64.18%) cases of TCC were superficial or in early stage (pTa and pT1) while 24(35.82%) showed muscle invasion.Conclusions: Transitional cell carcinoma was the most common bladder cancer. Most of thesetumours were high grade. A large percentage of high grade carcinomas presented with muscleinvasion. Pathological grade and muscle invasion are the most valuable prognostic predictorsof survival. The importance of including smooth muscle in the biopsy specimens needs to beemphasized._______________________________________________________________________________________Keywords: cancer; high grade; low grade; transitional tumour; urinary bladder._______________________________________________________________________________________

Clinical factors determining the efficacy of urinary bladder tumour treatments in dogs: Surgery, chemotherapy or both?

2012 ◽  
Vol 60 (1) ◽  
pp. 55-68 ◽  
Author(s):  
Tamás Molnár ◽  
Péter Vajdovich
Keyword(s):  
Urinary Bladder ◽  
Bladder Tumour ◽  
Transitional Cell ◽  
Clinical Factors ◽  
Survival Times ◽  
High Incidence ◽  
Close Relationship ◽  
Assessment And Treatment ◽  
Urinary Bladder Tumour ◽  
Disease Free

In a study of 44 canine patients suffering from histopathologically proven urinary bladder tumour with a high incidence of transitional cell carcinoma (TCC) (n = 35), a close relationship was found either between the disease-free period and the age (r = −0.40) of animals or between the survival times and the age (r = −0.62) of animals after treatment. In addition to the dog breeds known to be prone to have urinary bladder tumour, we found an additional potentially sensitive breed, the Hungarian Vizsla. The median survival times obtained by the applied treatment types were as follow: ‘surgery and chemotherapy’ (n = 8/44) 475 days, ‘surgery alone’ (n = 19/44) 240 days, ‘chemotherapy alone’ (n = 7/44) 31 days, and ‘no treatment’ (n = 10/44) 7 days (P < 0.001). According to the findings, chemotherapy combined with surgery completed in time is the most effective protocol in the treatment of urinary bladder tumour cases in dogs. A rational and more effective procedure for the assessment and treatment of urinary bladder tumour cases is presented.

scholarly journals Degeneration of the symphysis pubis presenting as a submucosal urinary bladder tumour

2012 ◽  
Vol 1 ◽  
pp. 55-58
Author(s):  
Tomasz R. Szopiński ◽  
Iwona Sudoł-Szopińska ◽  
Mariusz I. Furmanek ◽  
Tomasz Dzik ◽  
Piotr L. Chłosta ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Bladder Tumour ◽  
Symphysis Pubis ◽  
Urinary Bladder Tumour

scholarly journals A rare urinary bladder tumour

2014 ◽  
Vol 2014 (may15 1) ◽  
pp. bcr2013202994-bcr2013202994 ◽  
Author(s):  
J. E. M. Haddad-Lacle ◽  
C. J. Haddad ◽  
B. Villas
Keyword(s):  
Urinary Bladder ◽  
Bladder Tumour ◽  
Urinary Bladder Tumour

Clinical multi-colour fluorescence imaging of malignant tumours - initial experience

1998 ◽  
Vol 39 (1) ◽  
pp. 2-9 ◽  
Author(s):  
K. Svanberg ◽  
I. Wang ◽  
S. Colleen ◽  
I. Idvall ◽  
C. Ingvar ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Fluorescence Imaging ◽  
Bladder Tumour ◽  
Neck Region ◽  
Malignant Tumours ◽  
Head And Neck Region ◽  
Tumour Detection ◽  
Non Invasive ◽  
Urinary Bladder Tumour

Purpose: the detection of malignant tumours relies on a variety of diagnostic procedures including X-ray images and, for hollow organs, endoscopy. the purpose of this study was to present a new technique for non-invasive tumour detection based on tissue fluorescence imaging Material and Methods: A clinically adapted multi-colour fluorescence system was employed in the real-time imaging of malignant tumours of the skin, breast, head and neck region, and urinary bladder. Tumour detection was based on the contrast displayed in fluorescence between normal and malignant tissue, related to the selective uptake of tumour-marking agents, such as haematoporphyrin derivative (HPD) and δ-amino levulinic acid (ALA), and natural chromophore differences between various tissues. in order to demarcate basal cell carcinomas of the skin, ALA was applied topically 4–6 h before the fluorescence investigation. for urinary bladder tumour visualisation (transitional cell carcinoma of different stages including carcinoma in situ), ALA was instilled into the bladder 1–2 h prior to the study. Malignant and premalignant lesions in the head and neck region were imaged after i.v. injection of HPD (Photofrin). Finally, the extent of in situ and invasive carcinomas of the breast was investigated in surgically excised specimens from patients that received a low-dose injection of HPD 24 h prior to the study. the tumour imaging system was coupled to an endoscope. Fluorescence light emission from the tissue surface was induced with 100-nslong optical pulses at 390 nm, generated from a frequency-doubled alexandrite laser. with the use of special image-splitting optics, the tumour fluorescence, intensified in a micro-channel plate, was imaged in 3 selected wavelength bands. These 3 images were processed together to form a new optimised-contrast image of the tumour. This image, updated at a rate of about 3 frames/s, was mixed with a normal colour video image of the tissue Results: A clear demarcation from normal surrounding tissue was found during in vivo measurements of superficial bladder carcinoma, basal cell carcinoma of the skin, and leukoplakia with dysplasia of the lip, and in in vitro investigations of resected breast cancer Conclusions: the initial clinical experience of using multi-colour fluorescence imaging has shown that the technique has the potential to reveal malignant tumour tissue, including non-invasive early carcinoma and also precancerous tissue. Further investigations are needed to fully develop the method

scholarly journals En-bloc resection of urinary bladder tumour – a prospective controlled multicentre observational study

2020 ◽  
Author(s):  
Sławomir Poletajew ◽  
Wojciech Krajewski ◽  
Paweł Stelmach ◽  
Jan Adamowicz ◽  
Łukasz Nowak ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Observational Study ◽  
Bladder Tumour ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Urinary Bladder Tumour

Paediatric urinary bladder 'tumour' due to perforated appendicitis

2003 ◽  
Vol 33 (12) ◽  
pp. 900-901
Author(s):  
Bela Lombay ◽  
Istvan Csizy ◽  
Katalin Losonczi ◽  
Eva Borbas ◽  
Edit Nyari ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Bladder Tumour ◽  
Perforated Appendicitis ◽  
Urinary Bladder Tumour

scholarly journals Detection of bovine papillomavirus type 2 in the peripheral blood of cattle with urinary bladder tumours: possible biological role

2008 ◽  
Vol 89 (12) ◽  
pp. 3027-3033 ◽  
Author(s):  
Sante Roperto ◽  
Roberto Brun ◽  
Francesca Paolini ◽  
Chiara Urraro ◽  
Valeria Russo ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Peripheral Blood ◽  
Bladder Tumour ◽  
Biological Role ◽  
Bovine Papillomavirus ◽  
Simultaneous Presence ◽  
Adult Cattle ◽  
Blood Samples ◽  
Bladder Tumours

Bovine papillomavirus type 2 (BPV-2) infection has been associated with urinary bladder tumours in adult cattle grazing on bracken fern-infested land. In this study, we investigated the simultaneous presence of BPV-2 in whole blood and urinary bladder tumours of adult cattle in an attempt to better understand the biological role of circulating BPV-2. Peripheral blood samples were collected from 78 cattle clinically suffering from a severe chronic enzootic haematuria. Circulating BPV-2 DNA was detected in 61 of them and in two blood samples from healthy cows. Fifty of the affected animals were slaughtered at public slaughterhouses and neoplastic proliferations in the urinary bladder were detected in all of them. BPV-2 DNA was amplified and sequenced in 78 % of urinary bladder tumour samples and in 38.9 % of normal samples as a control. Circulating episomal BPV-2 DNA was detected in 78.2 % of the blood samples. Simultaneous presence of BPV-2 DNA in neoplastic bladder and blood samples was detected in 37 animals. Specific viral E5 mRNA and E5 oncoprotein were also detected in blood by RT-PCR and Western blot/immunocytochemistry, respectively. It is likely that BPV-2 can persist and be maintained in an active status in the bloodstream, in particular in the lymphocytes, as a reservoir of viral infection that, in the presence of co-carcinogens, may cause the development of urinary bladder tumours.

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