scholarly journals Selenium nanoparticles coated with resveratrol ameliorates the neurobiochemical abnormalities by attenuating oxidative stress and improving neurotransmissions in AlCl3-Induced Alzheimer’s model of rats.

2021 ◽  
Vol 41 (1) ◽  
pp. 173-177
Author(s):  
omayma Abo zaid ◽  
Samy Aziza ◽  
Sawsan EL-sonbaty ◽  
Mohsen Afifi
Keyword(s):  
Oxidative Stress ◽  
Selenium Nanoparticles

scholarly journals Selenium nanoparticles mitigate diabetic nephropathy and pancreatopathy in rat offspring via inhibition of oxidative stress

2021 ◽  
Vol 33 (1) ◽  
pp. 101265
Author(s):  
Iftekhar Hassan ◽  
Hossam Ebaid ◽  
Jameel Al-Tamimi ◽  
Mohamed A. Habila ◽  
Ibrahim M. Alhazza ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Nephropathy ◽  
Selenium Nanoparticles ◽  
Rat Offspring

scholarly journals Radiolytic Synthesis and Characterization of Selenium Nanoparticles: Comparative Biosafety Evaluation with Selenite and Ionizing Radiation

2021 ◽  
Author(s):  
Alline Gomes Pereira ◽  
Luanai Graziele Luquini Gerolis ◽  
Letícia Satler Gonçalves ◽  
Luciana Mara Costa Moreira ◽  
Pedro Lana Gastelois ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Sodium Selenite ◽  
Structural Parameters ◽  
Reactive Oxygen Species Generation ◽  
Protein Carbonylation ◽  
Selenium Nanoparticles ◽  
Spherical Particles ◽  
Water Radiolysis

Abstract Selenium nanoparticles (SeNPs) were synthesized by irradiating a solution containing sodium selenite (Se+4) as the precursor in YPG liquid medium with gamma-rays. Spherical particles were formed after reactions of sodium selenite with hydrated electrons (eaq-) and hydrogen radicals (H•) produced following water radiolysis. No hazardous reducing agents were employed. The obtained nanoparticles were morphologically characterized, and their physicochemical and structural parameters were analyzed. SeNPs characterization showed all selenium in the Se0 state. We incubated Saccharomyces cerevisiae cells with the SeNPs for 24 h and then challenged the cells with ionizing radiation. After radiation exposure, cells were assessed for cell viability, lipid peroxidation, protein carbonylation, free radical generation, and total sulfhydryl content. The synthesized SeNPs were considered safe and less toxic at the concentration employed than the same selenite concentration. Except for the protein carbonylation results, there were no other significant modifications in viability or the oxidative stress parameters in SeNP-treated cells. It was concluded that 1 mM of the synthesized SeNPs does not trigger oxidative stress. Furthermore, we verified that SeNPs attenuate the reactive oxygen species generation after in vitro ionizing radiation exposure. These observations open up tremendous possibilities for radiosensitizer development.

Selenium nanoparticles induce autophagy mediated cell death in human keratinocytes

Nanomedicine ◽  
2019 ◽  
Vol 14 (15) ◽  
pp. 1991-2010 ◽  
Author(s):  
Shrikant Kirwale ◽  
Venkatesh Pooladanda ◽  
Sowjanya Thatikonda ◽  
Sivasubramanian Murugappan ◽  
Amit Khurana ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Death ◽  
Potential Role ◽  
Apoptotic Cell ◽  
Human Keratinocytes ◽  
Apoptotic Cell Death ◽  
Selenium Nanoparticles ◽  
Mitochondrial Membrane Depolarization ◽  
Need To Evaluate ◽  
Therapeutic Properties

Aim: Selenium nanoparticles (SeNPs) may have a potential role in treating dermal disorders due to its wide therapeutic properties, but there is a need to evaluate its toxicity in keratinocytes. The present study evaluated the molecular mechanism and mode of cell death induced by SeNPs on dermal keratinocytes. Materials & methods: SeNPs were synthesized, characterized and studied in human keratinocytes cells. Oxidative stress and mitochondrial membrane depolarization were evaluated by various techniques. Additionally, autophagy mediated apoptotic cell death was evaluated. Results: SeNPs induced oxidative stress and apoptotic cell death in keratinocytes by increasing autophagy through the formation of acidic lysosomes and autophagosomes. Conclusion: Overall, SeNPs induce the oxidative stress and autophagy mediated apoptotic cell death in human keratinocytes cells.

Sodium selenite/selenium nanoparticles (SeNPs) protect cardiomyoblasts and zebrafish embryos against ethanol induced oxidative stress

2015 ◽  
Vol 32 ◽  
pp. 135-144 ◽  
Author(s):  
Kalimuthu Kalishwaralal ◽  
Subhaschandrabose Jeyabharathi ◽  
Krishnan Sundar ◽  
Azhaguchamy Muthukumaran
Keyword(s):  
Oxidative Stress ◽  
Sodium Selenite ◽  
Selenium Nanoparticles ◽  
Zebrafish Embryos

Protective role of biogenic selenium nanoparticles in immunological and oxidative stress generated by enrofloxacin in broiler chicken

2016 ◽  
Vol 45 (21) ◽  
pp. 8845-8853 ◽  
Author(s):  
Shubhangi Shirsat ◽  
Ambadas Kadam ◽  
Rajaram S. Mane ◽  
Vijaykumar V. Jadhav ◽  
Manohar K. Zate ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adverse Effects ◽  
Protective Effect ◽  
Broiler Chicken ◽  
Protective Role ◽  
Selenium Nanoparticles ◽  
And Oxidative Stress ◽  
Biogenic Selenium Nanoparticles

Biosynthesis of selenium nanoparticles and their protective effect in reducing adverse effects of enrofloxacin on broiler chicken are investigated.

scholarly journals Selenium Nanoparticles by Moderating Oxidative Stress Promote Differentiation of Mesenchymal Stem Cells to Osteoblasts

2021 ◽  
Vol Volume 16 ◽  
pp. 331-343
Author(s):  
Sabiha Fatima ◽  
Rawan Alfrayh ◽  
May Alrashed ◽  
Sarah Alsobaie ◽  
Rehan Ahmad ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Selenium Nanoparticles
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