scholarly journals Effect of Dietary Inclusion of Black Cumin (Nigella sativa) Seeds on Histological Parameters of Caecal Tonsils and Bursa of Fabricius in Broiler Chickens

2015 ◽  
Vol 7 (2) ◽  
pp. 33-39
Author(s):  
Somayeh Hamedi ◽  
Tahoora Shomali ◽  
Pooya Molayemvand
Keyword(s):  
Broiler Chickens ◽  
Nigella Sativa ◽  
Bursa Of Fabricius ◽  
Black Cumin

scholarly journals PROFIL DARAH (HEMOGLOBIN DAN HEMATOKRIT) BROILER JANTAN YANG DIBERI Nigella sativa (JINTAN HITAM) SEBAGAI IMUNOMODULATOR

2020 ◽  
Vol 4 (3) ◽  
pp. 151-156
Author(s):  
Rizki Tikadewi Noviani ◽  
Purnama Edy Santosa ◽  
Sri Suharyati ◽  
Siswanto Siswanto
Keyword(s):  
Drinking Water ◽  
Broiler Chickens ◽  
Clinical Laboratory ◽  
Nigella Sativa ◽  
Optimal Dose ◽  
Blood Profile ◽  
Black Cumin ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Black Cumin Seed

The purpose of this study was to determine the description of the blood profile especially hemoglobin and hematocrit of male broiler chickens that given Nigella sativa (black cumin seed). This research was conducted on 18 December 2019-16 January 2020 at the Integrated Field Laboratory, Faculty of Agriculture, Lampung University and Pramitra Biolab Indonesia Clinical Laboratory, Bandarlampung. This study used a completely randomized design (CRD) with 4 treatments and 3 replications. The treatments given in this study were broiler chickens drinking water without Nigella sativa (P0), drinking water with 36 mg/kg BW/day of Nigella sativa (P1), drinking water with 72 mg/kg BW/day of Nigella sativa (P2), drinking water with 144 mg /kg BW/day of Nigella sativa (P3). Data were analyzed descriptively (histogram). The results showed that application of Nigella sativa at a dose of 144mg /kg BW/day (P3) was the optimal dose to increase hemoglobin levels and hematocrit values of male broiler chicken. Keywords: Black cumin, hemoglobin, hematocrit, immunomodulator, male broiler, Nigella sativa

Optimisation of the Oil Extraction from Nigella sativa Seeds Using Response Surface Methodology

2017 ◽  
Vol 68 (2) ◽  
pp. 331-336
Author(s):  
Gabriela Isopencu ◽  
Mirela Marfa ◽  
Iuliana Jipa ◽  
Marta Stroescu ◽  
Anicuta Stoica Guzun ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Nigella Sativa ◽  
Polynomial Equation ◽  
Herbaceous Plant ◽  
Box Behnken Design ◽  
Pareto Analysis ◽  
Black Cumin ◽  
Mediterranean Countries ◽  
Experimental Values

Nigella sativa, also known as black cumin, an annual herbaceous plant growing especially in Mediterranean countries, has recently gained considerable interest not only for its use as spice and condiment but also for its healthy properties of the fixed and essential oil and its potential as a biofuel. Nigella sativa seeds fixed oil, due to its high content in linoleic acid followed by oleic and palmitic acid, could be beneficial to human health. The objective of this study is to determine the optimum conditions for the solvent extraction of Nigella sativa seeds fixed oil using a three-level, three-factor Box-Behnken design (BBD) under response surface methodology (RSM). The obtained experimental data, fitted by a second-order polynomial equation were analysed by Pareto analysis of variance (ANOVA). From a total of 10 coefficients of the statistical model only 5 are important. The obtained experimental values agreed with the predicted ones.

The protective effect of Nigella Sativa oil extract against neurotoxicity induced by Valproic acid

2017 ◽  
Vol 6 (9) ◽  
pp. 5474 ◽  
Author(s):  
Basant Mahmoud Morsy ◽  
Ghada Mohamed Safwat ◽  
Doaa Ahmed Hussein ◽  
Reem Mohamed Samy
Keyword(s):  
Valproic Acid ◽  
Nigella Sativa ◽  
Liver Lipid ◽  
Black Cumin ◽  
Enzymatic Antioxidant ◽  
Nigella Sativa Oil ◽  
Active Chemical ◽  
Oil Extract ◽  
Liver Lipid Peroxidation

Nigella sativa (NS), commonly known as black cumin, has been used for medicinal purposes. Traditionally the seeds and its oil are used in several diseases. The greatest part of the remedial properties of this plant is due to the presence of thymoquinone (TQ) which is a major active chemical component of the essential oil. The current study performed to evaluate the effect of Nigella sativa Oil (NSO) extract on the neurotoxic and hepatotoxic potentials from Valproic acid (VPA) administration. Also we summarize recent findings emphasizing the role of main neurotoxic and hepatotoxic markers and oxidative stress in study’s case. Neurotoxicity was induced by VPA at dose of (500 mg/kg b.wt) by gastric intubation daily for 30 day. These rats received NSO extract was given orally at dose of (0.5 ml/kg b.wt) daily for 30 days after VPA administration. The current results revealed that NSO extract treatment ameliorated significantly the elevated levels of the neurotoxic and hepatotoxic biomarkers which elevated as a result to VPA administration. Moreover, NSO extract treatment ameliorated the non-enzymatic antioxidant, brain and liver lipid peroxidation (LPO) and glutathione (GSH) concentration and the enzymatic antioxidant, brain and liver catalase(CAT) activity.

Therapeutic perspectives of the black cumin component thymoquinone: A review

2021 ◽  
Author(s):  
Chandan Sarkar ◽  
Sarmin Jamaddar ◽  
Tawhida Islam ◽  
Milon Mondal ◽  
Muhammad Torequl Islam ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Nigella Sativa ◽  
Pharmacological Properties ◽  
Black Cumin

The dietary phytochemical thymoquinone, obtained from the black and angular seeds of Nigella sativa, is a promising monoterpenoid hydrocarbons, which has been receiving massive attention for its therapeutic potential and pharmacological properties.

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