scholarly journals Ameliorative effect of ink extract and polysaccharide of Sepia officinalis on hepatotoxicity, renal toxicity and hematological disorders in adult male albino rats treated with cyclophosphamide

2021 ◽  
Vol 3 (3) ◽  
pp. 108-121
Author(s):  
A.A.A. Alshater ◽  
R.A. Ali ◽  
H.F. Dakhly
Keyword(s):  
Adult Male ◽  
Renal Toxicity ◽  
Albino Rats ◽  
Sepia Officinalis ◽  
Hematological Disorders ◽  
Ameliorative Effect

scholarly journals Ameliorative efficacy of Sepia officinalis ink extract on hepatorenal injury-induced following high-dose folic acid supplementation in rats

2021 ◽  
Vol 17 (3) ◽  
pp. 038-046
Author(s):  
Mariam T Elrouby ◽  
Sara B Ali ◽  
Nagat Saleh Hossuin Moftha ◽  
Abdeljalil Mohamed Al Shawoush ◽  
Ayman S. Mohamed
Keyword(s):  
Kidney Injury ◽  
Folic Acid Supplementation ◽  
Total Serum ◽  
Albino Rats ◽  
High Dose ◽  
Sepia Officinalis ◽  
High Intake ◽  
Stress Markers ◽  
Ameliorative Effect ◽  
Serum Aminotransferases

Sepia ink, a black suspension of melanin granules, is a multifunctional marine bioactive material. The present study aims to evaluate the ameliorative effect of the ink extract (IE) of the cuttlefish (Sepia officinalis) during high dosage administration of the FA in rats. Kidney injury induced by a single oral dose of FA (250 mg /kg). Eighteen male Wistar albino rats were the control, FA group, and FA+ IE group (250mg/kg). The IE showed a significant ameliorative effect against hepatorenal injury induced by high intake of FA as evident by decreasing the levels of serum aminotransferases (AST and ALT), urea, creatinine, uric acid, and significantly increased total serum albumin. Treatment with IE normalized the antioxidant status of the injured animals by reducing the MDA and the significant increase in the levels of GSH and CAT. The present study revealed that IE had an insightful effect against hepatorenal injury-induced following high intake of FA in rats, as it alleviates the alterations in the oxidative stress markers.

scholarly journals Ameliorative Effect of Omega-3 on Energy Drinks - Induced Pancreatic Toxicity in Adult Male Albino Rats

2019 ◽  
Vol 42 (2) ◽  
pp. 324-334
Author(s):  
Asmaa El Desouky ◽  
Ahmed Abo Zaid ◽  
Ghada El Saify ◽  
Dalia Noya
Keyword(s):  
Adult Male ◽  
Energy Drinks ◽  
Albino Rats ◽  
Omega 3 ◽  
Ameliorative Effect ◽  
Pancreatic Toxicity
Sign in / Sign up

Export Citation Format

Share Document