scholarly journals Features of mothers’ emotional experience during the hospitalization of newborns in connection with hypoxic affection of the central nervous system

2021 ◽  
Vol 11 (1) ◽  
pp. 89-102
Author(s):  
Irina Mamaychuk ◽  
◽  
Julia Milanich ◽  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Emotional Experience ◽  
Ischemic Injury ◽  
Full Term ◽  
Term Infants ◽  
The Central Nervous System ◽  
Injury Grade ◽  
Grade Ii ◽  
Hypoxic Ischemic Injury

Mothers of newborns with central nervous system pathology tend to experience more severe psychological distress and difficulty in forming a favourable relationship to their child than mothers of healthy infants. To provide psychological assistance, there is a need to better understand the features of the experience that parents find stressful and which ones are positive, in order to cope with stress. The objective of the research was to study mothers’ emotional experience during the hospitalization of newborns with hypoxic affection of the central nervous system (CNS). The research included 40 women admitted together with their children to the newborn pathology department: 22 mothers of full-term infants with hypoxic-ischemic injury (grade II and III), 18 mothers of preterm infants (29–34 weeks) with hypoxic-ischemic injury (grade II and III), intraventricular hemorrhage (grade II and III), and combined ischemic and hemorrhagic damage. Women responded to the questions of the original clinical-psychological interview and the data was processed qualitatively and quantitatively. The article describes the factors and content of negative and positive emotions of mothers in the period of hospitalization. The data on the contradictory nature of mothers’ reports of their feelings is presented: answers to direct questions are chiefly of a positive or ambivalent emotional background, while answers to projective questions primarily reflect a negative emotional background. It is shown that with a combination of prematurity and hypoxic affection of the child’s CNS, women have a more negative emotional background than that of the respondents who had delivered a full-term child. Conclusions are made about the effect of attitude on a “socially desirable” response during the description of the emotional experience, about less favorable emotional experience of mothers who delivered children prematurely with the pathology of the CNS.

Responses of the central nervous system to acute hypoxic-ischemic injury and related conditions

2007 ◽  
pp. 289-305
Author(s):  
Hideo H. Itabashi ◽  
John M. Andrews ◽  
Uwamie Tomiyasu ◽  
Stephanie S. Erlich ◽  
Lakshmanan Sathyavagiswaran
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Ischemic Injury ◽  
The Central Nervous System ◽  
Hypoxic Ischemic Injury

Fructose-1,6-Diphosphate, when Given Five Minutes after Injury, Does Not Ameliorate Hypoxic Ischemic Injury to the Central Nervous System in the Newborn Pig

Neonatology ◽  
1991 ◽  
Vol 59 (2) ◽  
pp. 98-108 ◽  
Author(s):  
Michael H. LeBlanc ◽  
Lorenzo A. Farias ◽  
Angel K. Markov ◽  
Owen B. Evans ◽  
Blake Smith ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Ischemic Injury ◽  
The Central Nervous System ◽  
Hypoxic Ischemic Injury

Fructose-l,6-bisphosphate does not ameliorate hypoxic ischemic injury to the central nervous system in the newborn pig

1992 ◽  
Vol 20 (9) ◽  
pp. 1309-1314 ◽  
Author(s):  
MICHAEL H. LEBLANC ◽  
COLETTE C. PARKER ◽  
VIBHA VIG ◽  
EDWARD E. SMITH ◽  
EDWIN G. BROWN
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Ischemic Injury ◽  
The Central Nervous System ◽  
Hypoxic Ischemic Injury

scholarly journals Fetal growth restriction: features of somatomental development in infancy

2018 ◽  
Vol 99 (3) ◽  
pp. 397-401
Author(s):  
N S Dolgova ◽  
S D Yavorskaya
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Full Term ◽  
Growth Restriction ◽  
Dynamic Monitoring ◽  
First Year ◽  
Term Infants ◽  
Short Period

Aim. To determine the features of physical and somatic health of full-term infants with fetal growth restriction during the first year. Methods. A retrospective analysis of 100 neonatal medical records of full-term infants was performed. All children were divided into 2 groups: group 1 - full-term infants, who were diagnosed with fetal growth restriction at birth (n=50), group 2 - full term infants born with normal body weight (n=50). Control points of comparison were neonatal period, months of life 1, 3, 6 and 12. Overall anthropometric data (length, weight, head and chest circumference), incidence and structure of morbidity and child's key system involvement were assessed. Results. Full-term newborns with fetal growth restriction present a risk group of growth and weight gain retardation during infancy, perinatal disorders of central nervous system persistent in 28±12% of cases by year 1 and, consequently, restriction of psychomotor (16±10%) and pre-verbal development (16±10%). Full-term low birth-weight newborns are characterized by short period of breast feeding and are included into the group of frequently ill children. The most vulnerable system, except for central nervous system, is the respiratory system. Conclusion. Children born with fetal growth restriction by the full term of gestation require special approach: diagnosis of and degree of central nervous system perinatal disorders at the first minutes of life, dynamic monitoring and personalized rehabilitation and preventive measures during the first year of life.

scholarly journals NEUROSONOGRAPHIC STUDY OF CHILDREN WITH HYPOXIC-ISCHEMIC BRAIN IJURY

2020 ◽  
pp. 7-11
Author(s):  
Volotko L. O.
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Injury ◽  
Brain Tissue ◽  
Ischemic Injury ◽  
Ischemic Brain ◽  
Destructive Processes ◽  
The Brain ◽  
Hypoxic Ischemic Injury

The study is aimed at neurosonographic characteristics of brain injury in newborn patients with perinatal hypoxic-ischemic injury of central nervous system, complicated with inflectional process (meningitis, ventriculitis). It is settled that brain immaturity, hydrocephalic syndrome, ischemia of the brain tissue and intraventricular hemorrhages are found 2 times more often in infants with perinatal hypoxic-ischemic injury of central nervous system, complicated with inflectional process. This fact generally characterizes disorders of the hemato-encephalic barrier and the development of destructive processes in the tissue of the brain.

scholarly journals Mathematical Analysis of Evaluating the Homocystein Level in Serum as a Predictor of Meningitis Development in Newborn with Hypoxic-Ischemic Injury of the Central Nervous System

2020 ◽  
Vol 5 (6) ◽  
pp. 102-109
Author(s):  
L. O. Volotko ◽  
Keyword(s):  
Oxidative Stress ◽  
Central Nervous System ◽  
Nervous System ◽  
Regression Analysis ◽  
Premature Infants ◽  
Mathematical Analysis ◽  
Roc Analysis ◽  
Full Term ◽  
Assay Method ◽  
The Central Nervous System

The main reason for the development of neonatal hypoxic-ischemic encephalopathy is inadequate oxygen supply to brain tissue, due to a combination of hypoxemia and ischemia. Hypoxia leads to disruption of oxidative processes and the development of acidosis, decreased energy balance of the cell, an excess of excitatory neurotransmitters, impaired metabolism of glia and neurons. Excess homocysteine can also induce a cascade of events in hippocampal neurons, producing in response to acute bacterial meningitis and accumulating in the central nervous system, reaching neurotoxic levels. Understanding the pathological mechanisms of neonatal ischemic Brain injury will help optimize treatment and reduce the degree of hypoxic-ischemic damage. The purpose of the study was to assess the level of homocysteine in the blood serum as a predictor of the development of meningitis in newborns with hypoxic-ischemic lesions of the central nervous system using mathematical analysis. Material and methods. The following research methods were used in the course of work: clinical-anamnestic (subjective and objective examination data), laboratory (biochemical, immunological method, enzyme-linked immunosorbent assay method), instrumental (neurosonography), methods of mathematical statistics. Statistical processing of all obtained results performed on a personal computer using the license software package Statistics 13.0 (StatSoftInc, serial number JPZ8041382130ARCN10-J) and MS Excel. We used the following methods of statistical analysis in the study: descriptive statistics, parametric and nonparametric methods of comparison of mean groups, correlation analysis, multiple linear and logistic regression analysis, utility statistics: odds ratio, relative risk, ROC analysis. Results and discussion. The relationship between homocysteine and hemoglobin and gestational age was found to be direct and reversed with bilirubin. The use of linear regression analysis allowed predicting the value of homocysteine by known values of one or more predictor variables. A ROC analysis was performed to assess the diagnostic significance of homocysteine levels as an indicator of oxidative stress and to express it in some integral indicators. Conclusion. The analysis showed that high levels of homocysteine in newborns can be considered as a statistically significant indicator of oxidative stress and a predictor of meningitis in premature infants. The probability of developing meningitis in premature infants with high homocysteine levels is 1.15 times higher than in full-term infants with central nervous system lesions (p> 0.05) and 8 times higher (p <0.05) than in full-term relatively healthy infants

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