scholarly journals Pattern of Abo & Rh blood groups in Multan region

Author(s):  
Muhammad Arif Mahmood ◽  
Abdul Hameed Anjum ◽  
Tarin S M A ◽  
Fiq S R ◽  
Man M U ◽  
...  

The discovery of various blood group systems has an immense importance in transfusion medicine and medico legal field. The association of certain blood groups with various diseases like peptic ulcer is well established. ABO and Rh blood groups are the main systems to cause blood transfusion reactions. An individual blood group today, is as important as national identity card. In cases of emergency blood transfusion, the blood group data of a population is very much important. The frequency of ABO and Rh blood groups vary throughout the world. It has been observed that group B diminishes in frequency from East to West. ABO and Rh blood group data is well established in Karachi and Lahore areas, but the data is not available from Multan region. In this study six thousands young healthy voluntary blood donors of either sex belonging to Multan region comprising of 5476 males and 524 females were included from "Blood Transfusion Center Nishtar Hospital Multan" and "Fatmid Blood Transfusion Center Multan". The commonest blood group observed in this study was "B" with frequency of 36.95%. The next common was group "0" with frequency of 33.8% followed by group "A" with frequency of 21.92% and group "AB" 7.33%. The frequency distribution of Rh blood group shows that 92.17% of the subjects are Rh-+ve & 7.83% are Rh--ve.

2000 ◽  
Vol 6 (1) ◽  
pp. 156-158
Author(s):  
T. Pramanik ◽  
S. Pramanik

The frequencies of ABO and rhesus blood groups vary from one population to another. We studied blood group distribution in 120 Nepalese students; 34% were blood group A, 29% group B, 4% group AB and 32.5% group O. The frequency of Rh-negative blood was 3.33% and Rh-positive 96.66%


2008 ◽  
Vol 41 (02) ◽  
pp. 138-140
Author(s):  
Rasoul Gheisari ◽  
Mehdi Ghoreishian ◽  
Movahedian Bijan ◽  
Roozbehi Amrolah

ABSTRACT Background: Blood group is a genetic characteristic which is associated with some diseases and deformities. Multifactorial characteristics of facial development make it difficult to predict a genetic pattern in a specific maxillofacial deformity, but epidemiological evaluations can reveal relationships between such deformities and some genetic characteristics or accompanied diseases, and this will help to recognise and treat them. The aim of this study is evaluation of the relationship between blood groups and maxillofacial deformities. Materials and Methods: In this study, blood groups of 190 patients with maxillofacial deformities who had had orthognathic surgery in Alzahra hospital, Isfahan, were compared with the general Iranian population. Results: Among 190 patients, 93 cases (49%) were men and 97 cases (51%) were women. Fifteen cases (8%) were < 20 years old, 130 cases (68%) were 20-30 years old, and the others (45 cases, 24%) were > 30 years old. The blood group distribution in our samples was as follows: blood group O = 76 cases (40%), blood group A = 58 cases (30%), blood group B = 41 cases (22%), and blood group AB = 15 cases (8%). Among these patients, 31 cases (16%) had maxillary deformities and 27 cases (14%) suffered from mandibular deformities while the other 132 cases (70%) had bimaxillary problems. The Chi-square test showed statistically significant differences between the blood group distribution of the patients of this study and the normal Iranian population ( P < 0.001). Conclusion: It was shown that among different blood groups; those with blood group B have a greater likelihood of association with maxillofacial deformities. On the other hand, the probability of the association of such deformities was the least with blood group A.


2020 ◽  
Vol 10 (03) ◽  
pp. 421-425
Author(s):  
Suad Azeez Hassan ◽  
Suhair Hassan Alkutbi ◽  
Eman S. Nassir ◽  
Haider Hassan Lilo

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are counted as a public health issue worldwide. The virus is transmitted to infect others through blood and blood products. Appointed blood groups and Rh-positive are more prone to the transmission of the infection by blood transfusion. The aim of this study is to find out the frequency of hepatitis B and C in apparently healthy blood donors and whether there is an association between ABO and Rh blood groups. ABO blood groups and their relationship with HBV and HCV infections were studied in 87,124 blood donors of both genders. Out of these donors, 353 individuals were found to be infected with HBV and HCV with a ratio of 1:250. The study was conducted between January to June 2018, which was presented to the Central Blood Bank in Baghdad and Al-Razi Medical Centre. It found that most hepatitis B and C blood donors were blood group O with a prevalence of 33.7 and 45.5%, respectively, while the results for those with blood group A showed 28.5 and 22.7% HBV and HCV infections, respectively. On the other hand, the incidence of HBV in individuals with blood group B was 29.8%, and HCV was 23.8%. AB blood group donors demonstrated the least incidence at 7.9% for both HBV and HCV. In conclusion, it has been found that there is a significant association between blood groups and Rh factor with hepatitis B and C infections.


Author(s):  
A. B. Ibrahim ◽  
H. Attahiru ◽  
O. Erhabor ◽  
P. F. Udomah ◽  
A. Yakubu ◽  
...  

ABO, Rhesus D and subgroups of ABO are highly immunogenic and are the common cause of antibody production in mismatched blood transfusions, haemolytic transfusion reaction and maternal alloimmunization. The aim of this study was to determine the occurrence of ABO, Rh D and subgroups of ABO among blood donors attending Specialist Hospital Sokoto, Nigeria. ABO, Rhesus D and subgroups of ABO antigen status of 176 blood donors with mean age of 30.44 ± 8.210 years attending Specialist Hospital Sokoto were determined using tile method for ABO and Rh D and conventional tube method for anti- A1, anti- H reagents for ABO subgroups respectively. Among the 176 subjects tested, blood group O+ was the most frequent group with 93 (52.8%), 39 (22.2%) were blood group B+, 37(21.0%) were blood group A+, 5 (2.8%) were blood group AB+, 2 (1.1%) were blood group O-. No data was obtained for A-, B- and AB- blood groups.  Out of 37 A blood groups obtained, 31 (83.8%) had A1 antigens and 6 (16.2%) had A2 antigens. Out of the 5 AB blood groups, all had A1B antigens. The study also shows that there was statistically significant difference between blood group A and ethnic groups (Hausa, Fulani and Yoruba) (p<0.05). Blood group O was found to be the most frequent followed by B, A and AB except among Hausa which revealed a pattern of O> A> B> AB. ABO, subgroups shows majority had A1 followed by A2 and A1B respectively.


2019 ◽  
Vol 26 (08) ◽  
pp. 1333-1338
Author(s):  
Muhammad Tahir ◽  
Gohar Ali ◽  
Ali Ismail

The objective of this study was to determine the blood groups among the patients presenting with ischemic stroke either AB blood group or O blood group is more common (frequent) among these patients irrespective of other known factors responsible for stroke. Study Design: Descriptive, Cross-sectional study. Setting: Department of Medicine, Nishtar Hospital Multan. Period: January 2015 to August 2015. Materials & Methods: We included total 292 patients (40-70 years of age), with ischemic stroke documented on CT scan brain of both gender (male and female). Blood sample of these patients were sent to the central laboratory of Nishtar hospital for blood group determination using standard techniques. Results: Mean age was 56.26 ± 8.28 years. Out of the 292 patients, 163 (55.82%) were male and 129 (44.18%). Frequency of blood group A, B, AB and O in patients with ischemic stroke was found to be 114 patients having blood group A (39.04%), 53 patients having blood group B (18.15%), 26 patients having blood group AB (8.90%) and 99 patients having blood group O (33.90%) respectively. Conclusion: Our study results concluded that there is an association between ABO blood groups and ischemic stroke, irrespective of other risk factors. Our study results have observed that individuals belonging to non-O blood groups (A, B, or AB) are at an increased risk of ischemic stroke as compared to O blood group carriers however we did not control possible impact of confounders such as diabetes, hypertension and dyslipidemia etc. Many studies proved that persons with AB blood groups are at increased of atherosclerosis but no study showed that these persons have increased risk of ischemic stroke or not.


1999 ◽  
Vol 41 (5) ◽  
pp. 285-289 ◽  
Author(s):  
Fátima Regina VILANI-MORENO ◽  
Maria Sueli Parreira de ARRUDA ◽  
Simone Guadgnucci CLARO ◽  
Elaine Valim Camarinha MARCOS ◽  
Somei URA

The authors investigated the relationship between dermatophytosis and ABO blood groups through blood typing, identification of isolated dermatophytes and specific cellular immune response of 40 individuals carriers of this mycosis. They verified that the fungus Trichophyton rubrum, isolated from 54.5% of the patients, was more frequent in individuals belonging to blood group A. The cellular immune response, evaluated through the trichophytin antigen, was positive in 25% of the studied patients; the presence of immediate reactions (30 minutes) was verified in 35%. The blood group distribution among patients with dermatophytosis and control groups was, respectively: 47.5% X 36% in group A, 40% X 50% in group O, 12.5% X 11% in group B. Even though the authors have found a higher number of patients belonging to blood group A infected by T. rubrum, these results suggest that there is no statistical evidence that these individuals are more susceptible to dermatophytosis.


2005 ◽  
Vol 12 (04) ◽  
pp. 368-371
Author(s):  
ABDUL REHMAN ◽  
Muhammad Akram Saeed ◽  
MUHAMMAD AYUB KHAN ◽  
Ahmad Rafique ◽  
MUHAMMAD ASHRAF ◽  
...  

`Objective: To know the prevalence of ABO and Rhesus blood groups.Design: Observational cross sectional study. Setting: Blood transfusion Center Tehsil Headquarter HospitalLiaquatpur. Subjects and Methods: The data of blood donors from 2001 to 2003. Results: Total numbers of donorsstudied were 1389. The commonest ABO blood group was O present in 44.56% (CL 41.97% - 47.20%) followed byB in 32.54% (CL 30.13% - 35.06%), A in 20.88% (CL 18.82% - 23.10%) and AB in 2.02% (CL 1.39% - 2.91%) donorswhile 90.35% (CL 88.68% - 91.80%) donors were Rh +ve and 9.65% (CL 8.20% - 11.32%) were Rh -ve. Thecommonest ABO +ve group was O +ve present in 40.03% (CL 37.48% - 42.69%) followed by B +ve in 30.31% (CL27.95% - 32.78%), A +ve in 18.21% (CL 16.27% - 20.34%) and AB +ve in 1.8% (CL 1.21% - 2.66%) donors. The mostcommon ABO -ve was O -ve present in 4.54% (CL 3.56% - 5.77%), A -ve in 2.66% (CL 1.93% - 3.66%), B -ve in 2.23%(CL 1.57% - 3.17%) donors. Conclusion: Blood group O is the commonest ABO blood group and 90.35% are RH +vein this area.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Biruk Legese ◽  
Molla Abebe ◽  
Alebachew Fasil

Background. ABO and Rh blood group antigens are thought to be among genetic determinants of type 2 diabetes mellitus. Identification of blood group phenotypes are more associated with type 2 diabetes mellitus. It will be helpful for individuals who are susceptible blood groups to take care of themselves by avoiding other predisposing factors and taking preventive measures. Methods. Hospital-based comparative cross-sectional study was carried out from February to April 2019 at Felege Hiwot Comprehensive Referral Hospital. Sociodemographic and clinical data were collected with a semistructured pretested questionnaire. ABO and Rh Blood group were determined by slide and test tube methods. Biochemical parameters were determined with Mindray BS-200E fully automated clinical chemistry analyzer. Data were analyzed by IBM SPSS version 20 statistical software. Chi-square test and logistic regression analysis were employed for data analysis. A P value of < 0.05 was considered statistically significant. Results. From a total of 424 participants included for this study, blood group O was found higher in frequency with 74 (34.9%) and 97 (45.75%) for cases and healthy controls, respectively. ABO blood groups showed significant association with T2DM, a chi-square value of 12.163 and P value of 0.007. However, the Rh blood group was not associated with T2DM. Binary logistic regression analysis revealed that blood group B had a higher risk (OR: 2.12, 95% CI: 1.33-3.32) and blood group O had decreased risk (OR: 0.636, 95% CI: 0.43-0.94) of T2DM as compared to other blood groups. Conclusion. ABO blood group antigens showed significant association with type 2 diabetes mellitus. Blood group B was associated with an increased risk and O blood group with decreased risk of type 2 diabetes mellitus.


Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 254-254 ◽  
Author(s):  
Letian Dai ◽  
Shawn Cotton ◽  
Alistair Macartney ◽  
Geoffrey Savidge ◽  
Anwar Alhaq

Abstract Plasma levels of vWF are known to be influenced by ABO blood groups, although the mechanism remains unresolved. Group O individuals have a significantly lower level of plasma vWF than those with group A, B or AB. This relative lower level of plasma vWF may result in a bleeding tendency and a shorter half-life of infused factor VIII in group O individuals. The formation of immune complexes between vWF and autoantibodies has been shown to accelerate vWF clearance from plasma in acquired von Willebrand syndrome. However, so far no evidence has been presented that the presence of autoantibodies against vWF is involved in lowering plasma level of vWF in group O individuals. In the present study, plasma samples were obtained from 199 healthy blood donors of blood group O (50), group A (50), group B (49), and group AB (50). A time-resolved fluorescence immunoassay (TRFIA) was developed to detect anti-vWF IgG in plasma samples. Briefly, 100 μl of diluted plasma was loaded on to duplicated vWF-coated and untreated control wells of a microplate. After incubation and washing, 100 μl of Europium-labeled anti-human IgG conjugate (1:500 dilution) was added to the plate to detect vWF IgG. The time-delayed fluorescence was then measured with a Victor microplate reader (PerkinElmer, Turku, Finland). The fluorescence counts of the control wells were subtracted from those of the vWF-coated wells. The results show that anti-vWF IgG was present in all four blood groups (Table 1). Of these blood groups, group O had the highest anti-vWF IgG level with 9.8 x 105 fluorescence counts, which was 2.7- to 3.5-fold higher than that of group A, B or AB. There was a significant difference in the anti-vWF IgG levels between group O and the rest of group A, B or AB. Quantitative analysis of plasma vWF by ELISA showed that the concentration of plasma vWF of group O was 29 to 35% lower than that of group A, B or AB (Table 1). These results suggest that TRFIA is a sensitive assay for detection of anti-vWF IgG in plasma samples, and the presence of the high level of anti-vWF Ig G in group O individuals may be responsible for lowing plasma vWF by acceleration of vWF clearance. Anti-VWF IgG levels and vWF concentrations in diffeent ABO blood groups Group O (n=50) Group A (n=50) Group B (n=49) Group AB (n=50) Data are presented as a mean ± SD. *P<0.01 compared with group A, B or AB. +P<0.01 compared with group A,B or AB. Anti-vWF IgG (x 105 Fluorescence counts) 9.8 ± 6.9* 2.8 ± 2.8 3.1 ± 3.0 3.6 ± 3.5 Concentration of vWF (% of normal controls) 116 ± 42+ 165 ± 46 165 ± 42 179 ± 49


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