scholarly journals A multispectral 3D-Endoscope for Cholesteatoma Removal

2020 ◽  
Vol 6 (3) ◽  
pp. 257-260
Author(s):  
Eric L. Wisotzky ◽  
Jean-Claude Rosenthal ◽  
Anna Hilsmann ◽  
Peter Eisert ◽  
Florian C. Uecker

AbstractWe present a stereo-multispectral endoscopic prototype using a filter-wheel to guide the removal of cholesteatoma tissue in the middle ear. An image-based method is used that combines multispectral tissue classification for the detection of tissue to be removed and 3Dreconstruction to determine its metric dimensions. The multispectral illumination used for tissue classification ranges from λ = 400 nm to λ = 500 nm with step-size of 20 nm, which results in six different narrow-band illumination modes. For classical RGB imaging and metric calculations, a broadband illumination mode is applied before and after the narrow-band illumination. The spectral information is augmented into the broadband mode using an overlay technique. The combination of multispectral imaging with stereoscopic 3D-reconstruction results in new valuable visualization of intraoperative data. This allows to generate a 3D-model of the patients anatomy highlighting the identified malicious tissue and compare the anatomical dimensions with pre-operative CT data.

2018 ◽  
Vol 06 (07) ◽  
pp. E830-E837 ◽  
Author(s):  
Kazumi Togo ◽  
Tetsuya Ueo ◽  
Kenshi Yao ◽  
Kurato Wada ◽  
Hideho Honda ◽  
...  

Abstract Background and study aims The presence of white opaque substance (WOS) is an endoscopic marker of intestinal metaplasia. Considering that the nature of WOS is absorbed lipid droplets, lipase plays an important role in the lipid absorption process and is inactivated at strong acidity. WOS may only be present in a hypochlorhydria state following Helicobacter pylori infection, and, thus, may not be highly sensitive marker, especially in H. pylori-eradicated patients. We investigated the relationship between WOS and gastric acid conditions. Patients and methods A total of 501 patients were retrospectively evaluated for the presence of WOS at 2 regions of interest using magnifying narrow-band imaging. The pH level of collected gastric juice was also measured. Study end points were (1) prevalence of WOS and its relationship with gastric juice pH in 3 groups: H. pylori-uninfected, H. pylori-infected, and H. pylori-eradicated; (2) the relationship between prevalence of WOS and gastric juice pH before and after proton pump inhibitor (PPI) administration in 29 H. pylori-eradicated cases. Results Prevalence of WOS was 0 % (0 /206), 28.4 % (31/109), and 3.2 % (6/186) in the H. pylori-uninfected, H. pylori-infected, and H. pylori-eradicated groups, respectively. Mean gastric juice pH was significantly higher in WOS-positive cases than in WOS-negative cases in the H. pylori-infected and H. pylori-eradicated groups (P < 0.0001). Mean gastric juice pH increased from 1.1 to 6.9 after PPI administration and WOS prevalence increased from 0 % (0/29) to 45 % (13/29) of cases. Conclusion The prevalence of WOS is closely associated with the neutralization of intragastric pH.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ali Abdulkareem Al-Shabkhon ◽  
Adel Ahmed Halim Emam ◽  
Ahmed Abd Elfattah Afify

Abstract Background Immunologic background of vitiligo, role of vitamin D on its pathogenesis, role of NB-UVB on its treatment and its stimulatory effect NB-UVB on VDR expression are challenging area of research. The current study will focus on evaluating the effect of NB-UVB on serum and tissue level of vitamin D in vitiligo patients and correlating it with the degree of improvement. Aim of the study The aim of the present study is to evaluate and compare the serum and tissue vitamin D level in vitiligo patients before and after NB- UVB therapy and correlate them together and with the degree of improvement. Patients and methods A case-control study included 16 vitiligo patients and 16 age and sex matched healthy controls. All patients will be examined by one dermatologist (demonstrating the extent of depigmentation according to rule of nines), and photographs will be taken before and after phototherapy to be evaluated by two different dermatologists to document the extent of repigmentation. Estimation of serum level of vitamin D by ELISA Results Five of the 15 patients achieved more than 55% repigmentation; the mean duration of disease was 13 months. The remaining 10 patients had 30% - 40% repigmentation.


1978 ◽  
Vol 100 (2) ◽  
pp. 246-252 ◽  
Author(s):  
H. S. Nagaraj ◽  
D. M. Sanborn ◽  
W. O. Winer

Infrared temperature measurements, ferrographic analysis, and surface profilimetry were used to monitor asperity interactions in a sliding EHD point contact. The contact temperature and surface profile signals obtained both before and after a run-in period are compared in the frequency domain by means of a Fourier analyzer. The interaction of surface asperities is accompanied by the presence of a high frequency component in the infrared signal. It is also shown that only a relatively narrow band of wavelengths of the surface profile spectrum are relevant in the interaction process.


2018 ◽  
Vol 32 (01) ◽  
pp. 1750275 ◽  
Author(s):  
T. M. Shabelnyk ◽  
O. V. Shutylieva ◽  
S. I. Vorobiov ◽  
I. M. Pazukha ◽  
A. M. Chornous

Co(5 nm)/Dy(t[Formula: see text])/Co(20 nm)/S and Ni(5 nm)/Dy(t[Formula: see text])/Ni(20 nm)/S trilayer films are prepared by electron-beam sputtering to investigate the influence of dysprosium layer thickness (t[Formula: see text]) and thermal annealing on the crystal structure, magnetoresistance (MR) and magnetic properties of thin films. The thickness of Dy layer changed in the range from 1 nm to 20 nm. The samples annealed for 20 min at 700 K. Electron diffraction patterns reveal that the as-deposited and annealed systems Co/Dy/Co and Ni/Dy/Ni had fcc-Co + hcp-Dy and fcc-Ni + hcp-Dy phase state, respectively. It is also shown that at the t[Formula: see text] = 15 nm the transition from amorphous to crystalline structures of Dy layer is observed. An increase in the Dy layer thickness results in changes in the MR and magnetic properties of the trilayer systems. It is shown that MR is most thermally stable against annealing to 700 K at t[Formula: see text] = 15 nm for Co/Dy/Co as well as for Ni/Dy/Ni. For t[Formula: see text] = 15 nm the, value of MR for both system increases by two times compared to those of pure ferromagnetic (FM) samples. The coercivity (B[Formula: see text]), remanent (M[Formula: see text]) and saturation (M[Formula: see text]) magnetization of the in-plain magnetization hysteresis loops are related to the Dy layer thickness too. The coercivity depends on the FM materials type and diffusion processes at the layer boundary. Accordingly, M[Formula: see text] and M[Formula: see text] are reduced with t[Formula: see text] increasing before and after annealing for both trilayer systems.


2012 ◽  
Vol 13 (5) ◽  
pp. 341-348 ◽  
Author(s):  
Hayam Abdel Samie Aiad ◽  
Shawky Mahmoud El-Farargy ◽  
Mostafa Mohamed Soliman ◽  
Mohamed Abd El-Wahed Gaber ◽  
Shaymaa Abd El-Aziz Othman

1988 ◽  
Vol 134 ◽  
Author(s):  
C. Robin Hwang ◽  
Michael F. Malone ◽  
Richard J. Farris ◽  
David C. Martin ◽  
Edwin L. Thomas

ABSTRACTA novel method of preparing PBZT/nylon composite fibers by infiltrating nylon into pure PBZT fiber is described. The pure PBZT fiber formed a microfibrillar network structure during coagulation, which is effective in reinforcing the matrix in the “in-situ network” composite fibers (designated IC). These new composite fibers exhibit nearly indistinguishable mechanical properties as those of “molecular” composite fibers (MC) prepared from isotropic solutions before and after tension heat-treatment (E = 44 GPa, σ = 430 MPa, ε = 1.2 %, σc = 250 MPa, G = 1.75 GPa) for PBZT/nylon weight ratios equal to unity.The fine structure of pure PBZT and its composite fibers spun from isotropic solutions was characterized using techniques based on nitrogen adsorption, small-angle X-ray scattering, scanning and transmission electron microscopies. The structure of both type of composites was found to be a microfibrillar network of PBZT in a matrix of amorphous nylon. The average diameters of the PBZT microfibrils were in the range of 10 to 20 nm for the IC and 4 nm for the MC.


2011 ◽  
Vol 399-401 ◽  
pp. 1312-1319 ◽  
Author(s):  
Yang Cheng ◽  
Jun Wang ◽  
Yun Cheng Bao ◽  
Ya Li Ma ◽  
Guang Hui Wang

Abstract. Polythiophene nanoparticles prepared by W/O microemulsion method were found to be photocatalytically active for degradation of Orange II dye and methyl Orange. During the photodegradation of Orange II and Methyl Orange as organic dyes in UV/H2O2and UV irradiation systems using polythiophene nanoparticles as photocatalyst, it is exhibiting significant photocatalytic activity towards to double dyes in UV and UV/H2O2system. the diameter of spherical polymer nanoparticles is 100±20 nm which was characterized by TEM with good dispersity. Furthermore, its photocatalytic efficiency for degradation of Orange II and Methyl Orange under UV irradiation is 2.54 and 1.95 times higher than normal polythiophene composites relatively. According to the testment by Accelerated Surface Area and Porosimetry System, The true cause lay in the fact that the specific surface area of Polythiophene nanoparticles is 106.6 m2/g compared to normal Polythiophene is 24.2 m2/g, This conjugated polymer characterized by FTIR spectroscopies before and after photocatalytic reactions shows reliable chemical stability. In addition, it held excellent recovery ability and kept up their catalytic activity with indistinctive drop after six repeated utilization.


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