Editorial Personalized Medicine in Inflammatory Bowel Diseases: Myth or Reality?

2018 ◽  
Vol 19 (7) ◽  
pp. 721-721
Author(s):  
Laurent Peyrin-Biroulet ◽  
Silvio Danese
2019 ◽  
pp. 89-91
Author(s):  
Article Editorial

The major concern for the practitioner is to determine the correct approach to the treatment. The personalized medicine allows the modern practitioner to leverage the individual patient characteristics, preventing the development of complications and disability. What therapeutic possibilities do modern gastroenterologists have for the treatment of ulcerative colitis? We asked this question to the Chairman of the Russian Society for the Study of Inflammatory Bowel Diseases, Head of the Department of Gastroenterology of Vladimirsky Moscow Regional Clinical Research Institute, Doctor of Medical Sciences, Professor Elena Alexandrovna Belousova.


2018 ◽  
Vol 90 (2) ◽  
pp. 4-11
Author(s):  
A I Parfenov ◽  
O V Knyazev ◽  
A V Kagramanova ◽  
N A Fadeeva

Personalized medicine (personalized medicine, individualized medicine) represents the totality of methods of prevention of a pathological condition, diagnosis and treatment in the event of its occurrence, based on individual patient characteristics. Such individual characteristics include genetic, epigenetic, and transcript, proteome, metabolomic and metagenomic markers, as well as a set of variable phenotypic traits - both of the patient's body and its separate tissues or cells. For example, treatment of inflammatory bowel diseases (IBD) can most clearly show the importance of applying personalized approaches. Currently in the treatment of patients with IBD paid great attention to genetic studies, monitoring of the concentration of the biological drugs and the level of antibodies to them, the role of microbiota as a predictor of effectiveness of therapy of IBD. Used clinical, laboratory, instrumental methods, as well as new biomarkers to assess the forecasting efficiency of conservative therapy in IBD patient. In the future treatment of patients with IBD will include a number of personalized data in order to better predict outcomes of the disease in each patient and more accurately select the appropriate treatment regimen.


Sign in / Sign up

Export Citation Format

Share Document