Phytotherapy for wound healing: The most important herbal plants in wound healing based on Iranian etnobotanical documents

Author(s):  
Kamal Solati ◽  
Mehrdad Karimi ◽  
Mahmoud Rafieian-Kopaei ◽  
Naser Abbasi ◽  
Saber Abbaszadeh ◽  
...  

: Wound healing is a process which starts with inflammatory response after damage occurrence. This process happens by restoring the wound surface coating tissue, migrating fibroblasts to form the needed collagen, forming a healing tissue and finally contortion and extraction of the wound. Today, various drugs are used to heal the wound. However, the used drugs to repair wounds have some defects and side effects. In spite of all attempts to accelerate wound healing definitely, no safe drug has been introduced for this purpose. Therefore, the necessity of identifying herbal plants in ethnopharmacology and ethnobotany documents with healing effect is felt essential. In this article we tried to review and present Iranian effective medicinal plants and herbal compounds used for wound healing. Searching was performed on databases including ISI Web of Science, PubMed, PubMed Central, Scopus, ISC, SID, Magiran and some other databases. The keywords used included wound healing, skin treatment, medicinal plants, ethnobotany, and phytotherapy. In this regard, 139 effective medicinal plants on wound healing were identified based on ethnopharmacology and ethnobotanical sources of Iran. Medicinal plants such as Salvia officinalis, Echium amoenum, Verbascum spp., G1ycyrrhiza glabra, Medicago sativa, Mentha pulegium, Datura stramonium L., Alhagi spp., Aloe vera, Hypericum perforatum, Pistacia atlantica and Prosopis cineraria were the most important and effective medicinal plants on wound healing in Iran. These native Iranian medicinal plants are full of antioxidants and biological compounds and might be used for wound healing and preparation of new drugs.

2018 ◽  
Vol 5 (5) ◽  
pp. 2260-2267
Author(s):  
Marjan Vakili ◽  
Shokoufeh Ahmadipour ◽  
Parisa Rahmani

Background: Constipation refers to difficult or delayed bowel emptying lasting 2 weeks or more and causing anxiety and distress in patients, and it is one of the most common problems in children. To treat constipation, therapeutic measures such as nutritional methods, feedback training, osmotic laxatives and stimulants, as well as stool volume enhancers, are used; however, each has its own problems and side effects. Medicinal plants have been shown to be effective in the treatment of many diseases, including constipation. Therefore, this review was conducted to report the medicinal plants effective for constipation. Methods: In the current review, eligible articles indexed from databases such as ISI (Web of Science), PubMed, Scopus, Islamic World Science Citation Center, Scientific Information Database, and Magiran were retrieved using the keywords ‘constipation’, ‘children constipation’, ‘baby’s and newborn constipation’, ‘medicinal plants’, and ‘traditional medicine’. Results: Available evidence showed that the medicinal plants Olea europaea, Phaseolus vulgaris, Prunus armeniaca, Brassica oleracea var. italica, Malus domestica, Linum usitatissimum, Aloe vera, Vitis vinifera, Foeniculum vulgare, Ficus carica, Ricinus communis, Sesamum indicum, and Descurainia sophia are some of the most important medicinal plants for the treatment of constipation in traditional medicine. Conclusion: Herbal plants are important for isolation/ preparation of new drugs in the treatment of constipation in children. In future studies, it may be beneficial to further understand and classify herbal plants/remedies, based on their mechanisms, as laxatives in the treatment of constipation.


2019 ◽  
Vol 8 (2) ◽  
pp. 124-133
Author(s):  
Mukhammad Toha ◽  
Mokh Sujarwadi ◽  
Ida Zuhroidah

Background: Older adult patients who underwent hernia surgery commonly get obstacles in the process of wound healing as a result of decline of body functions. Aloe vera which contains of anti-inflammatory, anti-microbial and skin fibroblasts stimulator, can be used as adjunctive therapy in treating wounds.Objective: This study aimed to identify the effect of aloe vera extract and discharge planning to accelerate wound healing of older adult hernia surgery patients at dr. R. Soedarsono General Hospital, Pasuruan.Method: This study uses Quasi-Experimental with Static-group comparison approach. The population is all post-operative hernia patients aged 55-65 years at the operating room of dr. R. Soedarsono General Hospital, Pasuruan. The sample consists of 20 respondents taken according to the inclusion criteria. The independent variable is the treatment of wounds using aloe vera extract accompanied by discharge planning, while the dependent variable was the acceleration of wound healing especially inflammatory and proliferation phases. The data were collected through observation of macroscopic current wound care. Data were analyzed using nonparametric Mann Whitney test with significance level of < 0.05.Result: The results showed the effect of the treatment using aloe vera extract and discharge planning to accelerate wound healing of older adult hernia surgery patients, the inflammatory phase of healing occurs on the sixth day for inflammation, exudation, and edema (p = 0.022, p = 0.028, and p = 0.029, respectively). The proliferative phase occurs on day three with p = 0.015.Conclusion: This research indicates further research on the benefits of aloe vera and discharge planning for wound healing especially in older adult patients is required. Thus, a stronger basis for recommending aloe vera extract as complementary therapy for wound care is available. Key words: Aloe Vera, Discharge Planning, Surgical Wound, Older Adults Age.


2019 ◽  
Vol 6 (2) ◽  
pp. 264-269
Author(s):  
Masoud Sharifian ◽  
Afshin Hasanvand ◽  
Gholam Basati ◽  
Saber Abbaszadeh

Surgical Science is one of the branches of medical science that deals with surgical and medicinal interventions, which can cure surgical wounds, cuts, burns and so on. The accelerated recovery process has always been a concern for surgeons and physicians. Standard local antibiotic drugs such as silver nitrate, mafenide acetate, sulfadiazine silver and AgNO3 are also used to treat wounds which are associated with some complications. Considering the fact that no effective herbal remedy has been introduced for wound healing, the purpose of this review is to investigate and identify indigenous Iranian herbs used for wound healing after surgery, especially burn wounds. In this systematic review paper, published articles in the period 1952 to 2017 with keywords of surgery, wound healing, burns, herbs, etc. from databases such as SID, MEDLIB, ProQuest, Magiran, Europe PubMed Central and Google Scholar. Abstract and title of all articles were studied and non-relevant articles were deleted and remaining articles were used for review. Based on the results of the study, Malva sylvestris, Camellia sinensis, Aloe vera, Cydonia oblonga, Scrophularia striata, Centella asiatica, Arnebia euchroma, Calendula officinalis and Hypericum perforatum are the most important herbal remedies for burn restoration. The following is an explanation of the most important herbal remedies for native burn wounds in Iran.


Author(s):  
Mullaicharam Bhupathyraaj ◽  
Lakshmi Sreenath ◽  
Hanan Obaid Al-Habsi ◽  
Nirmala Halligudi

Acne is derived from the Greek word “acme” which means “prime of life”. It is mostly considered to be benign and self-limiting condition but if it is ignored than it can progress to lifetime presence and scaring of the skin. Almost 85% of adolescence are affected by acne and from here males are at higher ration that female due to testosterone level that causes increase size in sebaceous gland which in turn causes more production of sebum (oil production). Women are affected more during adulthood due to imbalance of premenstrual hormones and over use of oil based cosmetics. There are many different factors that contribute to acne formation and it has many different forms. Herbal medication are considered safer than allopathic medicines because allopathic medicines are associated with various side effects such as like contact allergy, local irritation, scaling, photosensitivity, itching, redness, skin peeling, necrosis of the skin etc. In this study there are 3 herbal plants were used to prepare cream formulation that were used to investigate the anti-acne property. The aim of this research work was to develop formulations and to perform its evaluation as an herbal anti-acne cream. The objective of this study was to focus on the ant-acne or anti-bacterial effect of the formulated polyherbal cream containing three plants, Thyme, Aloe Vera and Basil. The results showed that the formulation 10 showed potential anti-acne property had that twice more concentration of aloe Vera than basil and thyme.


Author(s):  
Paroma Arefin ◽  
Md. Shehan Habib ◽  
Aishawarya Arefin ◽  
Md. Saidul Arefin

Many herbal plants have been recorded in medicine for their usefulness in menstrual disorders, however, a few have been extensively examined for their pharmacological activities. These plants have been recorded to have usefulness in the management of painful menses, preventing miscarriages, prolonging birth, or inducing birth. Therefore, the effects of herbal plants on the contractility of the uterus will be investigated using the in-vitro experiment of the isolated rat uterus. The study aims to assess the most outstanding plants that are used to treat menstrual disorders, their uterine contractility properties, and adverse effects. The study will therefore acknowledge the importance of medicinal plants in the study of new drugs for regulating uterine contractility and propose suggestions for improving experiments involving medicinal plants on uterine contractility for drug development. The study will provide a direction as to whether the plant extract has drug development potential.


RSC Advances ◽  
2015 ◽  
Vol 5 (105) ◽  
pp. 86199-86213 ◽  
Author(s):  
Arunpandian Balaji ◽  
Muthu Vignesh Vellayappan ◽  
Agnes Aruna John ◽  
Aruna Priyadarshini Subramanian ◽  
Saravana Kumar Jaganathan ◽  
...  

In modern biomedical researches, theAloe veraextract has been engaged in the synthesis of various micro and nanoformulations based smart structures, which increased its competence in wound healing, tissue engineering and drug delivery applications.


Author(s):  
Marta Sánchez ◽  
Elena González-Burgos ◽  
Irene Iglesias ◽  
Rafael Lozano ◽  
María Pilar Gómez-Serranillos

Abstract Background The usage of medicinal plants as a key component of complementary and alternative medicine, has acquired renewed interest in developed countries. The current situation of medicinal plants in Spain is very limited. This paper provides new insights and greater knowledge about current trends and consumption patterns of medicinal plants in the Autonomous Community of Madrid (Spain) for health benefits. Methods A descriptive cross-sectional study was designed for a population-based survey on medicinal plants. The data were collected (May 2018 to May 2019) using semi-structured face-to-face interviews in independent pharmacies, hospital centers and primary care health centers in the Autonomous Community of Madrid. The survey had 18 multiple choice and open-ended questions. Quantitative indices were calculated: Fidelity Level (FL), Use Value (UV) and Informants Consensus Factor (ICF). Chi-square test was used for data analysis. Results Five hundred forty-three people were interviewed. The majority of the participants (89.6%) have used medicinal plants to treat health disorders in the past 12 months, mainly for digestive problems, sleep disorders and central nervous system diseases. A total of 78 plants were recorded, being Matricaria recutita, Valeriana officinalis, Tilia spp. and Aloe vera the most used. The highest UV was found for Mentha pulegium (UV 0.130) followed by Aloe vera (UV 0.097) and Vaccinium macrocarpon. (UV 0.080). The highest FL values were for Eucalyptus spp. (FL 90.47%) for respiratory conditions and, Matricaria recutita (85.55%) and Mentha pulegium (84.09%) for digestive problems. The highest ICF corresponded to metabolism and depression (ICF = 1), pain (ICF = 0.97), insomnia (ICF = 0.96) and anxiety (ICF = 0.95). Participants mostly acquired herbal medicines from pharmacies, herbal shops and supermarkets. Some side effects (tachycardia, dizziness and gastrointestinal symptoms) and potential interactions medicinal plants-drugs (V. officinalis and benzodiazepines) were reported. Conclusion Many inhabitants of the Autonomous Community of Madrid currently use herbal products to treat minor health problems. The most common consumer pattern are young women between 18 and 44 years of age with higher education. In order to confirm the pattern, further research should be focused to investigate current uses of medicinal plants in other Spanish regions.


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