Comparison of Surface Equivalent Dose in CBCT, Digital Panoramic and Intra-Oral X-Ray Generators Using InstadoseTM Device: An In-Vitro Study

Background: Radiation protection in the dental examination is often overlooked because the doses delivered are negligible. However, the volume of dental radiological examinations will constitute almost 15% of all the radiological examinations carried out in the medical field. Aim: This study aims to evaluate and compare the surface equivalent dose on various target organs from various radiology devices on the RINN phantom, and the effect of numerous scanning protocols on said dose using dosimetry badge (Instadose). Objectives: The main objective is to study surface equivalent doses delivered in various critical organ regions in the facial region with the help of an Instadose device and to compare the doses delivered between 2D programs against 3D programs. Materials and Methods: RINN phantom was mounted on a dental chair for use against Planmeca ProMax 3D Classic and Planmeca intraoral ProX. Models. An Instadose badge was placed on various anatomical landmarks, and radiographic exposure protocols were applied to vary the parameters. The equivalent dose was calculated by connecting the dosimeter to a laptop and performing an instant reading output on the Instadose software. Results: The Thyroid showed a mean of 0.350, 0.0000, 0.0133, and 0.0000 in response to exposure by intraoral machine ProX, Panoramic, CBCT, and CBCT in ULD mode respectively. The dose absorbed by the left salivary glands was found to be significantly lower than the right salivary glands in panoramic exposures. Conclusion: It was revealed that a significant reduction in the dose when applying the Ultra-Low Dose protocol was noticed, and it reached up to 100% in the thyroid. It was also noted that there is no need for a thyroid collar in CBCT and Panoramic exposures. Maintaining the KVp at a constant and the exposure time as a variant caused a change in the dose equivalent received by the floor of the mouth and the right salivary gland.

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P1591Assessment of flow disturbances in the right ventricle: an in vitro study using a novel heart model

EP Europace ◽

10.1093/ehjci/eux158.217 ◽

2017 ◽

Vol 19 (suppl_3) ◽

pp. iii339-iii339

Author(s):

U. Gulan ◽

AM. Saguner ◽

D. Akdis ◽

C. Brunckhorst ◽

M. Holzner ◽

...

Keyword(s):

Right Ventricle ◽

In Vitro Study ◽

Vitro Study ◽

Heart Model ◽

Flow Disturbances ◽

The Right

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P2834An in vitro study on the influence of increased heart rate on the right ventricular kinetic energy and shear stresses

European Heart Journal ◽

10.1093/eurheartj/ehy565.p2834 ◽

2018 ◽

Vol 39 (suppl_1) ◽

Author(s):

U Gulan ◽

A M Saguner ◽

D Akdis ◽

A Denegri ◽

M X Miranda ◽

...

Keyword(s):

Heart Rate ◽

Kinetic Energy ◽

Right Ventricular ◽

In Vitro Study ◽

Vitro Study ◽

Shear Stresses ◽

The Right

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Abnormal Action Potential Responses to Halothane in Heart Muscle Isolated from Malignant Hyperthermia-susceptible Pigs

Anesthesiology ◽

10.1097/00000542-199504000-00018 ◽

1995 ◽

Vol 82 (4) ◽

pp. 947-953. ◽

Cited By ~ 5

Author(s):

Norbert Roewer ◽

Clemens Greim ◽

Eckhart Rumberger ◽

Jochen Schulte am Esch

Keyword(s):

Malignant Hyperthermia ◽

Action Potentials ◽

Myocardial Function ◽

In Vitro Study ◽

Resting Potential ◽

Cardiac Symptoms ◽

Cardiac Dysrhythmias ◽

Malignant Hyperthermia Susceptible ◽

The Right

Background During human and porcine malignant hyperthermia (MH), cardiac dysrhythmias and altered myocardial function can be observed. It is unknown whether a primary abnormality in cardiac muscle contributes to the cardiac symptoms during MH. An abnormal response to halothane has recently been demonstrated in action potentials (APs) from MH-susceptible (MHS) human skeletal muscles. We investigated the electrophysiologic properties in trabeculae isolated from the right ventricles of normal (MHN) and MHS pigs. Methods The experiments were performed on electrically stimulated (1 Hz) trabeculae isolated from the right ventricles of MHS and MHN pigs. Resting membrane potentials, APs, and tension were measured with and without the presence of 1% halothane. In addition, the halothane-equilibrated muscles were exposed to caffeine in increasing doses (1, 2, and 4 mM). Results In the absence of halothane, resting potential and AP characteristics in MHS and MHN muscles did not differ significantly. Halothane did not alter resting potentials but produced different alterations in the APs in MHS and MHN muscles, whereas the decrease in twitch tension was identical. In contrast to reductions in the AP amplitude and duration in MHN muscle, halothane produced an enlargement of the APs in MHS muscle. The addition of caffeine caused nearly identical prolongations of AP duration in MHS and MHN muscles. Conclusions This in vitro study demonstrates that halothane produces abnormal alterations in the dynamic electric properties of the ventricular excitable membrane from MHS pigs. These results suggest a latent defect in the myocardium of MHS pigs that becomes apparent in the presence of MH-triggering agents.

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Friction Forces during Sliding of Various Brackets for Malaligned Teeth: An In Vitro Study

The Scientific World JOURNAL ◽

10.1155/2013/871423 ◽

2013 ◽

Vol 2013 ◽

pp. 1-11 ◽

Cited By ~ 5

Author(s):

Vito Crincoli ◽

Letizia Perillo ◽

Maria Beatrice Di Bisceglie ◽

Antonio Balsamo ◽

Vitaliano Serpico ◽

...

Keyword(s):

Friction Force ◽

In Vitro Study ◽

Friction Forces ◽

Orthodontic Wire ◽

Conventional Brackets ◽

Frictional Forces ◽

The Right ◽

Post Hoc ◽

Sliding Mechanics

Aims. To measure the friction force generated during sliding mechanics with conventional, self-ligating (Damon 3 mx, Smart Clip, and Time 3) and low-friction (Synergy) brackets using different archwire diameters and ligating systems in the presence of apical and buccal malalignments of the canine.Methods. An experimental setup reproducing the right buccal segment of the maxillary arch was designed to measure the friction force generated at the bracket/wire and wire/ligature interfaces of different brackets. A complete factorial plan was drawn up and a three-way analysis of variance (ANOVA) was carried out to investigate whether the following factors affect the values of friction force: (i) degree of malalignment, (ii) diameter of the orthodontic wire, and (iii) bracket/ligature combination. Tukey post hoc test was also conducted to evaluate any statistically significant differences between the bracket/ligature combinations analyzed.Results. ANOVA showed that all the above factors affect the friction force values. The friction force released during sliding mechanics with conventional brackets is about 5-6times higher than that released with the other investigated brackets. A quasilinear increase of the frictional forces was observed for increasing amounts of apical and buccal malalignments.Conclusion. The Synergy bracket with silicone ligature placed around the inner tie-wings appears to yield the best performance.

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Utilization Of Nano Ethanolic Extract Combination Chamber Bitter (Phyllanthus Niruri L.) And Garlic (Allium Sativum L.) As A Natural Immunomodulator In Nanoherbal Development, In Silico And In Vitro Study

JPSCR Journal of Pharmaceutical Science and Clinical Research ◽

10.20961/jpscr.v2i02.14394 ◽

2017 ◽

Vol 2 (02) ◽

pp. 110

Author(s):

Kadek Hendra Darmawan

Keyword(s):

Molecular Docking ◽

In Silico ◽

Allium Sativum ◽

In Vitro Study ◽

Ethanolic Extract ◽

Phagocytic Index ◽

Phyllanthus Niruri ◽

The Right ◽

Phagocytosis Activity

The Filantin compounds in chamber bitter (Phyllanthus niruri L.) and lectin in garlic (Allium sativum L.) was proven as immunomudulatory agents through interaction with Toll-Like Reseptors (TLR) which have role in innate immune responds. Immunomodulators drug available on the market still have many shortcomings such as the low potential. Drug developing by nanotechnology is the right solution to increase the potential of the drug by increasing the absorption and minimize the dose. This research aimed to know the interaction of filantin and lectin with TLR2-TLR1 receptors through molecular docking and produce the nanoemulsion combination of chamber bitter and garlic ethanolic extracts that have phagocytosis activity. In silico assay through molecular docking showed that filantin has affinity for binding to TLR2-TLR1, docking score of lectin (-33,5389) was lower than the filantin (-31.5112). That means lectin has higher affinity for binding to TLR2-TLR1. Nanoemulsion was formulated by SNEDDS methods with composition of co-surfactant: surfactant: oil is 1: 5,25: 1. The nanoemulsion stable at 0,414% (w/v). In vitro assay of phagocytic index (5,03) and ratio (95%) showed that the formulation with nanoemulsion of the combination has higher phagocyte index and ratio than the formulation without nanoemulsion or even the positive controls.

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In Vitro Study of Flow Regulation for Pulmonary Insufficiency Using Diode Valves

ASME 2007 Summer Bioengineering Conference ◽

10.1115/sbc2007-176723 ◽

2007 ◽

Author(s):

Tiffany A. Camp ◽

Stephanie Hequembourg ◽

Richard S. Figliola ◽

Tim McQuinn

Keyword(s):

Pulmonary Valve ◽

Pulmonary Regurgitation ◽

Circulatory System ◽

In Vitro Study ◽

Pulmonary Insufficiency ◽

Pressure Gradients ◽

Right Heart ◽

Mock Circulatory System ◽

The Right

The operating pressures in the right heart are significantly lower than those of the left heart and with marked differences in the circulation impedances. The pulmonary circulation shows a tolerance for mild regurgitation and pressure gradient [1]. Pulmonary regurgitation fractions on the order of 20% and transvalvular pressure gradients of less than 25mm Hg are considered mild [4]. Given this tolerance, we examine the concept of using a motionless valve to regulate flow in the pulmonary position. In a previous study, the use of fluid diodes was shown to be a promising concept for use as a pulmonary valve [2]. In this study, we test two different diode designs. For each diode valve, flow performance was documented as a function of pulmonary vascular resistance (PVR) and compliance. Tests were done using a pulmonary mock circulatory system [3] over the normal adult range of PVR and compliance settings.

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Making the right choice: Optimizing rt-PA and eptifibatide lysis, an in vitro study

Thrombosis Research ◽

10.1016/j.thromres.2010.07.020 ◽

2010 ◽

Vol 126 (4) ◽

pp. e305-e311 ◽

Cited By ~ 11

Author(s):

George J. Shaw ◽

Jason M. Meunier ◽

Christopher J. Lindsell ◽

Arthur M. Pancioli ◽

Christy K. Holland

Keyword(s):

In Vitro Study ◽

Vitro Study ◽

The Right

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Validation of anatomical landmarks-based registration for image-guided surgery: An in-vitro study

Journal of Cranio-Maxillofacial Surgery ◽

10.1016/j.jcms.2012.11.017 ◽

2013 ◽

Vol 41 (6) ◽

pp. 522-526 ◽

Cited By ~ 30

Author(s):

Yi Sun ◽

Heinz-Theo Luebbers ◽

Jimoh Olubanwo Agbaje ◽

Serge Schepers ◽

Luc Vrielinck ◽

...

Keyword(s):

In Vitro Study ◽

Vitro Study ◽

Image Guided Surgery ◽

Anatomical Landmarks ◽

Guided Surgery ◽

Image Guided

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Deformations During and Post Stenting of a Diseased Coronary Artery Phantom: An In Vitro Study

ASME 2009 Summer Bioengineering Conference, Parts A and B ◽

10.1115/sbc2009-206655 ◽

2009 ◽

Author(s):

Ronan Finn ◽

Tim McGloughlin ◽

Patrick Delassus ◽

Liam Morris

Keyword(s):

Coronary Artery ◽

In Vitro Study ◽

Clinical Problem ◽

Coronary Stenting ◽

Long Term Effects ◽

Stent Restenosis ◽

Symptomatic Coronary Artery Disease ◽

Artery Disease ◽

The Right

World-wide, deaths from cardiovascular diseases exceed those caused by cancer, infectious disease and trauma [1]. Coronary stenting is an established treatment for patients with symptomatic coronary artery disease. Although stents reduce restenosis rates in carefully selected lesions, in-stent restenosis remains a recognized clinical problem. Restenosis, defined as “the arterial healing response after injury during transluminal coronary revascularisation” [2], has been the principal drawback of coronary stenting since its conception nearly 30 years ago [3]. While there have been many studies on the short and long term effects of coronary artery stenting, less is known of the injury caused by the balloon and stent during the stenting process. The objective of this study is to fabricate compliant and morphologically realistic models of the right coronary artery (RCA) for preclinical bench-top testing of intraluminal stents, in diseased cases.

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