scholarly journals Health-Related Quality of Life Among Admitted HIV/AIDS Patients in Selected Ethiopian Tertiary Care Settings: A Cross-Sectional Study

2019 ◽  
Vol 12 (1) ◽  
pp. 532-540 ◽  
Author(s):  
Getandale Zeleke Negera ◽  
Teshale Ayele Mega

Background: The introduction of Combined Antiretroviral Therapy (cART) shifted the perception of HIV/AIDS from a fatal to a potentially manageable chronic disease. As a result, patient-perceived health-related quality of life (HRQoL) is becoming an important outcome measure among HIV infected patients. We assessed the quality of life of admitted HIV/AIDS patients and the association of socio-demographic, clinical, and psychosocial characteristics of patients with health-related quality of life. Methods: Health facility-based cross-sectional study was conducted from April 1 to May 31, 2018 in selected tertiary care hospitals of Ethiopia. HRQoL was measured at discharge using the interviewer-administered World Health Organization’s Quality of Life HIV short-form instrument (WHOQoL-HIV BREF). Data were entered into EpiData 3.2 and exported to SPSS version 21.0 for cleaning and analysis. Descriptive analytical results were reported in text and table. Logistic regression was conducted to identify predictors of poor quality of life. Variables with p-value ≤ 0.25 in bivariate regression were considered as a candidate for multivariable regression. Multivariable logistic regression was performed to identify independent predictors. Regression coefficients and their 95% confidence intervals together with p-value < 0.05 were used to identify independent predictor of poor QoL. Results: Majority, 56 (58.9%) of the study participants, had poor general health-related quality of life. Being unemployed (AOR: 4.1, 95% CI; (1.23, 13.64); p=0.02), lack of support from family (AOR: 3.6, 95% CI: (1.05-12.6); p=0.04), and having co-morbidity (AOR: 4.2, 95% CI: (1.08, 16.65); p=0.039) were found to be independent predictors of poor quality of life. Conclusions: The study showed that the majority of the participants had poor health-related quality of life which was affected by unemployment, co-morbidity, and social support from family.

2021 ◽  
Vol 71 (2) ◽  
pp. 629-33
Author(s):  
Nadia Ramzan ◽  
Samreen Misbah ◽  
Shehla Baqai ◽  
Syed Fawad Mashhadi ◽  
Imtenan Sharif ◽  
...  

Objective: The study was conducted to assess the maternal health related quality of life and its affecting factors in postpartum period. Study Design: Analytical cross-sectional study. Place and Duration of Study: The study was done in a tertiary care hospital, Rawalpindi, from Mar to Jun 2019.Methodology: By using non-probability purposive sampling technique, sample of 268 women in post-partum period were interviewed. A validated short form-36 (SF-36) Questionnaire was administered to women aged 15-49 years, who had spontaneous vaginal delivery or cesarean section, and were within six weeks up to six months of postpartum period. Data was analyzed by using SPSS-22. A p-value of ≤0.05 was taken as significant. Results: Highest median scores were reported in physical functioning 75 (55, 90) and social functioning 75 (75, 62). Lowest median scores were reported in energy fatigue 37 (31, 50) body pain 45 (22, 62) and general health 45 (30, 60). Health-related quality of life scores showed significant difference (p-value <0.05) among subgroups of time since delivery, mode of delivery, education of women, husband’s education and antenatal visits. Conclusion: The study showed that health related quality of life score of postpartum women was moderately affected; where in physical and social functioning domains strongly contributes in better quality of life. Energy/fatigue, body pain and general health are the weakest domains adversely affecting quality of life. Women in subacute postpartum phase, with cesarean section, lower educational status and less than 04 antenatal visits are associated with poorer HRQOL.


Author(s):  
S. Cynthia Subhaprada ◽  
Shasank R. V. S. S. ◽  
T. Sivakala ◽  
S. Madhusai

Background: HIV/AIDS is known to affect an individual not only physically but also mentally, socially, and financially. It is a syndrome that builds a vacuum in a person affecting his/her life as a whole. Combined with ART, Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). The objective of this study is to assess health related quality of life of HIV/AIDS patients attending ART clinic Tertiary care hospital, GGH, Kurnool and to determine the association of socio-demographic and disease related variables with health related quality of life.Methods: A cross-sectional study was conducted from April 2019 to June 2019 involving 400 purposively selected HIV-positive patients of age >18 years, who were taking highly active anti-retroviral therapy for the past 6months from the ART center, GGH, Kurnool. After obtaining IEC clearance and informed consent, WHOQOL-BREF instrument was used for data collection. Data analysis was performed using IBM SPSS version 26.0.Results: Out of the 400 participants, 60% were males. The mean age of the participants was 38.5±10.54 years. Overall quality of life had a mean score of 69.71. Physical (82.57) and level of independence (78.78) domains showed higher mean score when compared to psychological (63.82), environmental (61.49) and Social (60.26) domains.Conclusions: Among study subjects 15.5% had excellent QoL (≥80), nearly 69.75% had good QoL (60-79) and 14.75% had poor QoL (<60). Low QoL scores were seen in the social domain, suggesting that more social interventions are required in this population.


2017 ◽  
Vol 16 (1) ◽  
pp. 14-18
Author(s):  
Sabina Shrestha ◽  
Aparajita Manoranjan ◽  
Sushan Man Shrestha

Introduction: Strabismus affects the quality of life of adults both in functional and psychosocial aspect of life. This study was conducted to compare the health related quality of life in adults before and after strabismus surgery.Methods: It was a prospective quantitative study conducted in Nepal Eye Hospital from Sep 2015 to July 2016. Thirty one adult participants with strabismus undergoing strabismus surgery completed the study. Twenty open ended adult strabismus questionnaire (AS-20) were used to assess the health related quality of life of adults before and one month after strabismus surgery.Results: The overall median score of adult strabismus questionnaire for quality of life improved from 68.75 (Interquartile range (IQR 25) to 91.25 (IQR 17.5) after strabismus surgery (p value < 0.00). Similarly, the median function subscale and median psychosocial subscale also improved from 72 (IQR 25) to 95 (10) and from 55 (IQR 37.5) to 90 (IQR 15) respectively after surgery. Conclusion: The quality of life of adult strabismic patients improved significantly after stabismus surgery.


2020 ◽  
pp. 1-2
Author(s):  
Arer AR ◽  
Hulagbali M

A study was conducted on 90 children suffering with thalassemia who are attending thalassemia unit of KLES Dr. Prabhakar Kore Charitable Hospital Belagavi. To assess the health related quality of life of children with thalassemia and to find out the association between health related quality of life of children with Thalassemia and selected demographic variables. Purposive sampling technique was used to select the samples. Data was collected using standardized paediatric inventory quality of life (PedsQL 4.0 Generic Core Scales) tool. Data obtained was tabulated and analysed in terms of objectives of the study using descriptive and inferential statistics. The study revealed that Majority 70 (77.78%) of thalassemia children had average level of quality of life where as minimum 10 (11.11%) of thalassemia children had low and high level of quality of life. The association between age groups and levels of QOL is found to be not statistically significant (Chi-square= 6.3530, p=0.1740) and the association between religions and levels of QOL is found to be not statistically significant.


2021 ◽  
Author(s):  
Ruwaydah Ahmed Meelad ◽  
Intan Juliana Abd Hamid ◽  
Zarina Thasneem Zainudeen ◽  
Ilie Fadzilah Hashim ◽  
Muhd Nur Akmal Azizuddin ◽  
...  

Abstract Purpose: Primary immunodeficiency disease (PID) affects various aspects of a patient’s life. However, the health-related quality of life (HRQOL) of PID patients in Malaysia patients is poorly described. This study aimed to determine the quality of life of Malaysian PID patients and parents. Method: This cross-sectional study was performed from August 2020 to November 2020. Patients with PID and their families were invited to answer the PedsQL Malay version (4.0) questionnaire, the tool used to assess the HRQOL. A total of 41 families and 33 patients with PID answered the questionnaire. A comparison was performed with the previously published value of healthy Malaysian children. Result: Parent of respondents recorded a lower mean of total score than the parents of normal healthy children (67.26±16.73 vs. 79.51±11.90, p-value = 0.001, respectively). PID patients reported lower mean total score to normal healthy children (73.68 ± 16.38 vs. 79.51 ± 11.90, p-value = 0.04), including psychosocial domain (71.67±16.82 vs. 77.58±12.63, p-value = 0.05), and school functioning, (63.94±20.87 vs. 80.00 ± 14.40, p-value = 0.007). No significant difference of reported HRQOL when comparing between subgroup of PID on immunoglobulin replacement therapy and those without immunoglobulin replacement (56.96±23.58 vs. 65.83±23.82, p-value 0.28). Socioeconomic status was found to be predictive of the lower total score of PedsQL in both parent and children reports. Conclusion: Parents and children with PID, especially those from middle socioeconomic status, have lower HRQOL and school function impairment than healthy children.


2021 ◽  
Vol 12 (02) ◽  
pp. 376-381
Author(s):  
Arokiasamy Senthilkumar ◽  
Lakshminarayanan Subitha ◽  
Essakky Saravanan ◽  
Dinesh Kumar Giriyappa ◽  
Santhosh Satheesh ◽  
...  

Abstract Background Globally, coronary artery disease (CAD) was the leading cause of health losses. The emergence of revascularization has brought a major change in the management of CAD. Depression and cardiovascular diseases (CVD) are the two highly prevalent noncommunicable diseases (NCD), which lead to poor quality of life and high socio-economic loss for the patient. The rate of depressive episodes was higher in CAD population in comparison to population with other heart problems. Objectives The primary objective of the current study is to determine the proportion of those with depressive symptoms through Patient Health Questionnaire-9 (PHQ-9) among CAD patients in a tertiary care public hospital. Methods It was a cross-sectional analytical design, which assess the percentage of patients with depressive symptoms among CAD patients, using a pretested, semistructured questionnaire. The PHQ-9 and EuroQoL five-dimensional three-level (EQ-5D-3L) questionnaire, a quality-of-life instrument (five items), were used, which was validated in the Tamil version. Statistical Analysis Categorical variables was expressed as proportion. We used Chi-square as a statistical test to calculate the p value and risk estimation with 95% CI. Results Out of 541 patients, 159 (30%) patients had mild-to-moderate depressive symptoms, of which 144 (89%) participants were greater than 50 years. In EQ-5D-3L, around one-third of the participants reported pain or discomfort and anxiety or depression. Conclusion The study concludes that the assessment of health-related quality of life (HRQoL) is becoming increasingly important in the management of CAD patients. Studies have shown that depression predicts subsequent quality of life, while others have shown that HRQoL is a risk factor for ongoing depression. Treatment of depression may improve subsequent physical HRQoL; hence, it is vital to address both during their follow-up to improve outcomes among patients with CAD.


2016 ◽  
Vol 14 (1) ◽  
pp. 29-32
Author(s):  
Sabina Shrestha ◽  
Aparajita Manoranjan ◽  
Sushan Man Shrestha

Introduction: Strabismus is known to affect health related quality of life in adults. This study was conducted to compare the quality of life among strabismic and non strabismic visually normal adults.Methods: A prospective cross sectional study was conducted at Nepal Eye Hospital for two years. Fifty three adults with strabismus and fifty three adults without strabismus and normal vision were enrolled. Twenty open ended adult strabismus questionnaire (AS-20) developed by Hatt et al were used to assess the impact of strabismus on patient’s health related quality of life. All the participants reviewed AS-20 instructions for patients prior to completing the questionnaire. The overall AS-20 score was calculated as a mean of all 20 item scores. The psychosocial subscale was calculated as a mean of items 1-10 (inclusive). Function subscale was calculated as a mean of items 11-20 (inclusive).The mean overall and subscale scores were compared between strabismic patients and non-strabismic visually normal adults using Mann Whitney U test.Results: Mean overall scores decreased for patients with strabismus as compared to non strabismic visually normal adults. Mean psychosocial scale among strabismic patients and non strabismic patients was 47.53 ± 24.840 and 95.42 ± 9.631 respectively and mean function subscale among the two groups were 63.57±22.652 and 83.91±13.592 respectively. There was statistical difference in the overall score, psychosocial as well as function subscale between the strabismic and non strabismic visually normal adults (p value 0.00).Conclusion: The overall quality of life appears to be adversely affected in people with strabismus in comparison to the ones without strabismus. Strabismus, being a treatable condition, should not be ignored and corrective measures should be undertaken.


2020 ◽  
Author(s):  
Shaojie Li ◽  
Yongtian Yin ◽  
Lijun Chen ◽  
Guanghui Cui ◽  
Jiaqin Li ◽  
...  

BACKGROUND Older adults’ health literacy levels are crucial to improving health outcomes and health-related quality of life (HRQoL). However, the impact of eHealth literacy on HRQoL in older adults is unclear. OBJECTIVE The aim of this study was to examine the association between eHealth literacy and HRQoL of older adults and provide reference for the development of network intervention measures related to the health quality of life of the older adults. METHODS An anonymous cross-sectional survey was conducted among 1,201 adults aged 60 or older from Jinan, China. The eHealth Literacy Scale and Short-Form Health Survey (SF-12) were used to measure eHealth literacy and HRQoL. We used linear regression to test the adjusted association between eHealth literacy and HRQoL. RESULTS Most participants (88.9%) had inadequate eHealth literacy. Lower eHealth literacy was related to older age ( F=12.618, P<.001), female gender( t=3.303, P<.01), living in rural areas( F=11.356, P<.001), having less education( F=59.084, P<.001), being unmarried, divorced or widowed( t=4.416, P<.001), having a lower family income( F=38.017, P<.001), living with others(χ2=4.319, P<.05), and not having health insurance( F=12.713, P<.001). There were significant differences across physical functioning( t=-4.862, P<.001), role- physical( t=-2.485, P<.05), bodily pain( t=-3.470, P<.01), general health( t=-4.449, P<.001), vitality( t=-3.498, P<.001), role-emotional( t=-2.654, P<.01), mental health( t=-4.150, P<.001), physical component summary( t=-6.350, P<.001) and mental component summary( t=-4.483, P<.001) between adequate eHealth literacy and inadequate eHealth literacy. After controlling for age, gender, and other covariates, adequate eHealth literacy was positively related to physical component summary ( beta=7.6, P<.001) and mental component summary(beta=4.6, P=.001). CONCLUSIONS This study showed that Chinese older adults with higher eHealth literacy were more likely to contribute to higher HRQoL. Thus, Older adults’ eHealth literacy levels need to be taken into account when formulating health education and promotion programs for older adults, especially when the expected outcome is to improve HRQoL.


2020 ◽  
Author(s):  
Yaqun Huang ◽  
Sha Yan ◽  
Hongfu Xie ◽  
Ben Wang ◽  
Zhixiang Zhao ◽  
...  

BACKGROUND Rosacea is a chronic inflammatory dermatosis with facial skin involved, leading to physical and emotional problems, which greatly affected quality of life (QoL) of patients. Dermatology Life Quality Index (DLQI) and willingness to pay (WTP) are well-established instruments assessing the health-related quality of life (HRQoL), while very few studies have been focused on this topic about rosacea in China. OBJECTIVE To investigate HRQoL in Chinese rosacea patients assessed by DLQI and WTP and investigate potential predictors for patients with HRQoL severely affected. METHODS This cross-sectional study was conducted on 973 patients with rosacea. Sociodemographic data, clinical features and DLQI were collected, and WTP was assessed by three standardized items. Multivariable logistic analysis was performed to investigate independent factors influencing QoL. RESULTS 921 questionnaires were accomplished by participants. The mean DLQI score was 11.6 (median 11). Patients were willing to pay an average of $1050.2 or € 896.2 (median $431.4 or € 368.1) for complete cure. 33.3% would like to pay more than 20% of their monthly income to achieve sustainable control. There were positive correlations between WTP with DLQI (P < .05). DLQI could be independently impacted by age (21-30 and 31-40, OR = 3.242 and 3.617, respectively), the occupational requirement of appearance (high, OR = 4.410), disease duration (< 2 years, OR = 1.582), oedema (OR = 1.844) and severity of flushing, burning, stinging and pruritus (severe, OR = 2.003, 1.981, 2.491, 2.249, respectively). There were no significant associations between WTP and most of the clinical factors. CONCLUSIONS The QoL was negatively affected and should not be ignored among rosacea patients in China. Patients aged 21-40y, having occupational requirement of appearance, with the disease duration less than 2 years, and suffering severe flushing and related symptoms were more likely to have severe or very severe limitation of QoL.


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