scholarly journals Cross-sectional Study on Effects of Ondansetron and Meperidine in the Prevention of Postoperative Shivering after Spinal Anesthesia

2021 ◽  
Vol 15 (1) ◽  
pp. 34-39
Author(s):  
Sepideh Vahabi ◽  
Siavash Beiranvand ◽  
Arash Karimi ◽  
Bagher Jafari-Takab

Purpose: Post-anesthesia shivering is one of the most common problems after surgery and may lead to multiple complications such as hypoxemia, lactate acidosis and catecholamine release. The purpose of this study was to compare the effects of intravenous meperidine and ondansetron on postoperative shivering in patients having an elective cesarean section under spinal anesthesia. Design: Cross-sectional study Methods: In this cross-sectional study, 105 patients with the age of 18-45 years and ASA class I-II undergoing elective cesarean section were randomly assigned into three groups. Group O was administered 8mg ondansetron, group M patients were given 0.4mg/kg meperidine and group P was placebo that was administered with 2cc of saline intravenously after the delivery. The incidence and intensity of shivering and postoperative nausea was monitored and recorded by the trained nurse. The data obtained was analyzed using SPSS v18. Results: All three groups (n=35) had no significant difference in terms of age, weight and time of spinal anesthesia. Postoperative shivering was reported in 4 patients (11.4%) in group A and 3 patients (8.6%) in group B and in 14 patients (40%) in group C. The incidence of postoperative shivering was significantly less in groups A and B as compared to the placebo, p=0.03. The intensity of shivering was greater in group C as compared to groups A and B, p=0.01. The incidence and intensity of postoperative nausea was significantly less in group A, p=0.03, p<0.001, respectively, while no difference was reported in groups B and C, p<0.05. Conclusion: 8mg ondansetron and 0.4 mg/kg of meperidine are equally effective in managing postoperative shivering; however, ondansetron has an additional effect of reducing the incidence of postoperative nausea among patients undergoing caesarean section with spinal anesthesia.

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Neila Azka ◽  
Syahredi Syahredi ◽  
Eva Chundrayetti

AbstrakPada masa sekarang ini telah terjadi perubahan tren dalam persalinan, yaitu berupa peningkatan angka seksio sesarea. Peningkatan ini dipengaruhi berbagai faktor seperti: adanya kekhawatiran akan terjadinya cedera janin, peningkatan permintaan ibu untuk melakukan persalinan seksio sesarea, serta faktor sosioekonomi. Beberapa penelitian justru menunjukkan seksio sesarea dapat menimbulkan morbiditas pada bayi. Tujuan penelitian ini adalah membandingkan kondisi bayi antara persalinan normal dan seksio sesarea elektif dilihat dari nilai Apgar Penelitian dilaksanakan dari Mei 2014 sampai Januari 2014 di bagian rekam medis RSUP Dr. M. Djamil Padang.. Jenis penelitian yang digunakan adalah analitik dengan desain cross-sectional study. Sampel dalam penelitian ini terdiri dari 179  pasien dengan persalinan normal dan 56 pasien dengan seksio sesarea. Hasil penelitian menunjukkan bahwa pada menit pertama nilai Apgar 4-6 adalah 3,4% pada persalinan normal. Nilai Apgar 7-10 sebanyak 96,6% pada persalinan normal dan 100% pada seksio sesarea pada menit pertama. Pada menit kelima, nilai Apgar 4-6 adalah 1,1% pada persalinan normal, sedangkan nilai Apgar 7-10 sebanyak 98,9% pada persalinan normal dan 100% pada seksio sesarea pada menit kelima. Setelah dilakukan analisis dengan mann-whitney test didapatkan bahwa tidak terdapat perbedaan nilai Apgar pada menit-1 (p=0,777) dan menit-5 (p=0,887) antara persalinan normal dengan seksio sesarea.Kata kunci: persalinan normal, seksio sesarea elektif, nilai Apgar AbstractIn recent years, cesarean section have increased. Several factor are contributing, such as fears of injury to the fetus, increased women's request to do a cesarean section deliveries and socioeconomic factors. Some studies have also shown that cesarean section can lead to morbidity in infants. The objective of this study was to compare between Apgar scores of infant born by elective cesarean section and normal vaginal deliveries. The research was done from May 2013 to January 2014 at the medical records department of general hospital center Dr. M. Djamil Padang. This was an analytic study with cross-sectional study design. This study used 179 samples with normal vaginal delivery and 56 samples with cesarean section. The result showed that 1st minute Apgar score of 4-6 in normal vaginal delivery was 3.4%, and Apgar score 7-10 was 96.6% in normal vaginal delivery while in cesarean section was 100%. The 5th minute Apgar score of  4-6 in normal vaginal delivery was 1.1%, and Apgar score 7-10 was 98.9% in normal vaginal delivery while in cesarean section was 100%. After being analyzed using Mann-Whitney test, the study showed that there was no significant different in Apgar score of neonates born through normal vaginal delivery and neonates born trough cesarean section at first minute (p=0.777) and fifth minute (p=0.887).Keywords: normal vaginal delivery, elective cesarean section, Apgar score


2017 ◽  
Vol 9 (1) ◽  
pp. 14-17
Author(s):  
Kiran Javaid ◽  
Abida Sultana ◽  
Muneeba Faisal ◽  
Rahim Iqbal ◽  
Mohammad Bin Khalid ◽  
...  

ABSTRACT Aim To assess the indications of emergency vs elective cesarean section in patients at Holy Family Hospital, Rawalpindi. Materials and methods A descriptive cross-sectional study was conducted on 675 women who underwent cesarean section in the Gynecology and Obstetrics Department of the Holy Family Hospital, Rawalpindi, Pakistan over a period of 2 months. Sociodemographic features, type of cesarean, and their indications were recorded on a structured questionnaire. Data were analyzed by using Statistical Package for the Social Sciences version 23. Results A total of 675 women underwent cesarean section during the study period. The emergency cesarean section rate was 70.4%, while elective cesarean constituted of 29.6% cases. The most common indications for emergency cesarean were fetal distress (43.2%) followed by previous cesarean (19.2%) and failure to progress (9.3%), while that for elective cesarean were previous cesarean (41%) and malpresentation (24.5%). Conclusion Fetal distress and previous scar are the leading causes of cesarean section in our study. The improvement of maternal and child health facilities at basic health units, appropriate training of lady health workers and midwives, timely involvement of senior obstetrician, and formation of strict policies regarding cesarean section can have a profound effect in decreasing the rate of cesarean section. Clinical significance This study can prove to be of profound value in getting an insight into the continuously increasing rate of cesarean section. In developing countries like Pakistan, these increasing cesarean deliveries prove to be a burden on the already-constrained resources. How to cite this article Sultana A, Faisal M, Iqbal R, Javaid K, Khalid MB, Khalid MA. Indications of Emergency vs Elective Cesarean Section: Cross-sectional Study done at Holy Family Hospital, Rawalpindi, Pakistan. J South Asian Feder Obst Gynae 2017;9(1):14-17.


2020 ◽  
Vol 15 ◽  
Author(s):  
Arash karimi ◽  
Jahanbakhsh Nejadi ◽  
Mahnaz Shamseh ◽  
Nooshin Ronasi ◽  
Mehdi Birjandi

Background: Postoperative nausea and vomiting (PONV) is a common complication associated with the use of anesthesia. Several antiemetics are used to reduce the incidence and severity of PONV. The aim of this study is to investigate the role of dexamethasone and ondansetron to treat PONV in patients undergoing cesarean section (c-section) under spinal anesthesia. Methods: This double-blind clinical trial study was performed on patients who were referred to the operating room of Haji Karim Asali Hospital of Khorramabad for elective cesarean section in 2016-17. Upon meeting the inclusion criteria, patients were allotted into two groups (n=60). Group A received 8mg of dexamethasone and group B received 4mg of ondansetron after spinal anesthesia. The Visual Analog Scale (VAS) questionnaire and Depression-Anxiety-Stress Scale (DASS) questionnaire was used for the analysis. Patients with mild to moderate stress, anxiety, and depression were included in the study. Data were analyzed using SPSS 16 software. Results: There was no difference in the demographic data of the two groups. The mean severity of nausea in group A was significantly higher than in group B. The frequency of vomiting in group A was 20 times higher than group B, which was found to be statistically significant, p = 0.018. Concerning the type of delivery with the frequency of nausea, the results showed that the frequency of nausea in group A was 3.24 times higher than group B, however, this difference was not statistically significant, p = 0.106. Conclusion: Based on the results of this study, ondansetron had a significant effect on the alleviation of postoperative nausea and vomiting, as compared to dexamethasone in c-section surgical candidates.


F1000Research ◽  
2020 ◽  
Vol 8 ◽  
pp. 1755
Author(s):  
Shunji Suzuki

Background: Maternal mental status has been thought to be affected by the delivery modes. We examined the relation between delivery modes and the mental status of women who delivered at our institute in Japan. Methods: Data were collected from the medical charts of 643 primiparous women without a history of mental disorders who delivered singleton babies and underwent a 1-month postpartum check-up at our institute from September 2018 to June 2019. The maternal mental status was examined based on the scores of the Edinburgh Postnatal Depression Scale (EPDS) and the Mother-Infant Bonding Scale (MIBS). Results: The rate of high scores of the EPDS and the MIBS in women choosing elective cesarean section were higher than in women with vaginal delivery and emergency cesarean section. Conclusion: Mental health care may be necessary for women choosing elective cesarean section.


2021 ◽  
Vol 71 (5) ◽  
pp. 1582-84
Author(s):  
Hassam Anjum Mir ◽  
Mubashir Sharif ◽  
Ali Asif ◽  
Maleeha Shamim ◽  
Maaz Qureshi ◽  
...  

Objective: To determine if the traditional chewing stick Miswak was as effective in cleaning teeth as Toothbrush. Study Design: Cross sectional study. Place and Duration of Study: Armed Forces Institute of Dentistry, Rawalpindi, from Aug 2020 to Jan 2021. Methodology: A total of 300 subjects were included which were divided in two groups on the basis of whether they used miswak or toothbrush as a cleaning aid. Group A was toothbrush users and group B was Miswak user. Plaque Index was used to determine the cleanliness of teeth. The scores were recorded and data analyzed using SPSS-23. Results: The means and standard deviations of Plaque Index score for group A and B were 0.96 ± 0.58 and 0.98 ± 0.56 respectively. The comparison of Plaque Index score for both groups was insignificant with the p-value of 0.083. Conclusion: Within the limitations of this study, it is concluded that, no significant difference was found in the effectiveness of traditional miswak and tooth brush. It is recommended that if the technique of teeth cleaning is good then any of the abovementioned means of teeth cleaning can be used.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1755
Author(s):  
Shunji Suzuki

Background: Maternal mental status has been thought to be affected by the delivery modes. We examined the influence of delivery modes on the mental status of women who delivered at our institute in Japan. Methods: Data were collected from the medical charts of 645 primiparous women without a history of mental disorders who delivered singleton babies and underwent a 1-month postpartum check-up at our institute from September 2018 to June 2019. The maternal mental status was examined based on the scores of the Edinburgh Postnatal Depression Scale (EPDS) and the Mother-Infant Bonding Scale (MIBS). Results: The rate of high scores of the EPDS and the MIBS in women choosing elective cesarean section were higher than in women with vaginal delivery and emergency cesarean section. Conclusion: A fulfilling birth-plan and birth-review may also be necessary for women choosing elective cesarean section.


2019 ◽  
Vol 9 (2) ◽  
pp. 79-82
Author(s):  
Bharati Devi Sharma Regmi ◽  
Gopendra Prasad Deo ◽  
Subin Shrestha ◽  
Sabita Shrestha ◽  
Renuka Tamrakar Mishra

Background: Spinal anesthesia with hyperbaric bupivacaine provides a dense neural block in cesarean delivery but associated with side effects like hypotension, bradycardia nausea and vomiting. Addition of low dose fentanyl with low dose of hyperbaric bupivacaine may decrease the in­cidence of these complications. The aims of study was to compare the hemodynamic parameters (blood pressure and heart rate), nausea and vomiting with low dose intrathecal hyperbaric bupivacaine with fentanyl vs a conventional dose of intrathecal hyperbaric bupivacaine in patient undergoing elective cesarean section. Methods: Seventy-four pregnant women aged 20-35 years old which un­derwent elective cesarean section at Chitwan Medical College were ran­domized into two groups. One group received spinal anesthesia with 8mg of0.5% hyperbaric bupivacaine and 25μg fentanyl and another group re­ceived 12mg 0.5% bupivacaine. Results: The mean age, baseline heart rate, systolic and diastolic blood pressure were comparable in both groups. Significant difference in hypo­tension (24.31% vs. 62.16%, p<0.05) and Nausea and vomiting (16.20% vs. 27%, p<0.05) were found in bupivacaine-fentanyl group versus a conven­tional dose of spinal bupivacaine group. Conclusions: Low dose of bupivacaine with Fentanyl provides good spinal anesthesia for cesarean section with less hypotension, nausea and vomit­ing in comparison to bupivacaine alone.


2021 ◽  
Vol 10 (5) ◽  
pp. 997
Author(s):  
Ferrante S. Gragasin ◽  
Maria B. Ospina ◽  
Jesus Serrano-Lomelin ◽  
Su Hwan Kim ◽  
Matthew Kokotilo ◽  
...  

Background: Both high and low placental weights are associated with adverse pregnancy outcomes. Maternal hemoglobin levels can influence placental weight, but the evidence is conflicting. Since maternal hemoglobin does not invariably correlate with fetal/neonatal blood hemoglobin levels, we sought to determine whether cord blood hemoglobin or maternal hemoglobin status more closely associates with placental weight in women undergoing elective cesarean section at term. Methods: This was a cross-sectional study conducted at the Royal Alexandra Hospital, Edmonton, Canada, involving 202 women with term singleton pregnancies undergoing elective cesarean section. Maternal blood and mixed cord blood hemoglobin levels were analyzed using a HemoCue Hb201+ system. Birth weight, placental weight, one- and five-minute APGAR scores, American Society of Anesthesiologists physical state classification, maternal age, and maternal height were also recorded. Relationships between maternal and cord blood hemoglobin levels with placental weight, birth weight, and birth weight to placental weight ratio were the main outcome measures. Results: A total of 182 subjects were included in the analysis. Regression analysis showed that cord blood hemoglobin, but not maternal hemoglobin, was inversely related with placental weight (β = −2.4, p = 0.001) and positively related with the birth weight to placental weight ratio (β = 0.015, p = 0.001 and p = 0.63, respectively). Conclusions: Our findings suggest that measuring cord blood hemoglobin levels, rather than maternal hemoglobin levels, may provide important diagnostic information about in utero fetal adaptation to suboptimal placental function and neonatal health.


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