scholarly journals Transmission and Transmissibility of SARS-CoV-2: What We Know and What We Not

2021 ◽  
Vol 1 (1) ◽  
pp. 112-116
Author(s):  
Hiba Sami ◽  
Mohammad Shahid ◽  
Parvez Anwar Khan ◽  
Haris M Khan

Declared as a pandemic on March 11, 2020, COVID -19 has made it essential for the entire world to control and ensure safety measures for such infections in the future. To take any measures, one must be sure of the route of transmission of the agent causing Pandemic. With so many controversies in its mode of spread, COVID-19 has raised questions for the researchers to confirm its various modes of spread. Many of these modes can be overlooked; it is necessary to emphasize and illustrate them. The aim of this paper is to provide a brief overview of the various modes of COVID-19 transmission. According to the published literature, COVID-19 is primarily transmitted from person to person through oral and respiratory aerosols, with droplets from the virus-infected environment playing a minor role in disease transmission. The infection is particularly dangerous for healthcare workers and the elderly with comorbidities.

2019 ◽  
Vol 29 (1) ◽  
pp. 61-75 ◽  
Author(s):  
Antonia Graf ◽  
Marco Sonnberger

Although autonomous driving is expected to provide a solution for various mobility-related issues, ideas on how the technology will actually unfold are vague. Nevertheless, stakeholders in the field hold expectations about the technology and the future users. With very few exceptions, so far research does not focus on these expectations as social constructions of individuals and publics. In addition, these perceptions play only a minor role in the technology-centered debate. Thus, to bring these perceptions to light and to analyze their implications, we draw on the sociotechnical imaginaries approach to reconstruct stakeholders’ views of future users and publics. We perform a qualitative content analysis and show that imaginaries unfold along the themes of responsibility for the process of driving, rationality in decision-making, and acceptance for emerging technologies. We discuss how the themes relate to each other, what role science plays, and what implications follow from the respective stakeholders’ views.


2016 ◽  
Vol 16 (20) ◽  
pp. 12993-13013 ◽  
Author(s):  
Peter Huszár ◽  
Michal Belda ◽  
Jan Karlický ◽  
Petr Pišoft ◽  
Tomáš Halenka

Abstract. The regional climate model RegCM4.2 was coupled to the chemistry transport model CAMx, including two-way interactions, to evaluate the regional impact of urban emission from central European cities on climate for present-day (2001–2010) and future (2046–2055) periods, and for the future one only emission changes are considered. Short-lived non-CO2 emissions are considered and, for the future impact, only the emission changes are accounted for (the climate is kept “fixed”). The urban impact on climate is calculated with the annihilation approach in which two experiments are performed: one with all emissions included and one without urban emissions. The radiative impacts of non-CO2 primary and secondary formed pollutants are considered, namely ozone (O3), sulfates (PSO4), nitrates (PNO3), primary organic aerosol and primary elementary carbon (POA and PEC).The validation of the modelling system is limited to key climate parameters, near-surface temperature and precipitation. It shows that the model, in general, underestimates temperature and overestimates precipitation. We attribute this behaviour to an excess of cloudiness/water vapour present in the model atmosphere as a consequence of overpredicted evaporation from the surface.The impact on climate is characterised by statistically significant cooling of up to −0.02 and −0.04 K in winter (DJF) and summer (JJA), mainly over cities. We found that the main contributors to the cooling are the direct and indirect effects of the aerosols, while the ozone titration, calculated especially for DJF, plays rather a minor role. In accordance with the vertical extent of the urban-emission-induced aerosol perturbation, cooling dominates the first few model layers up to about 150 m in DJF and 1000 m in JJA. We found a clear diurnal cycle of the radiative impacts with maximum cooling just after noon (JJA) or later in afternoon (DJF). Furthermore, statistically significant decreases of surface radiation are modelled in accordance with the temperature decrease. The impact on the boundary layer height is small but statistically significant and decreases by 1 and 6 m in DJF and JJA respectively. We did not find any statistically significant impact on precipitation and wind speed. Regarding future emissions, the impacts are, in general, smaller as a consequence of smaller emissions, resulting in smaller urban-induced chemical perturbations.In overall, the study suggest that the non-CO2 emissions play rather a minor role in modulating regional climate over central Europe. Much more important is the direct climate impact of urban surfaces via the urban canopy meteorological effects as we showed earlier.


2019 ◽  
Vol 2 (1) ◽  
pp. Manuscript
Author(s):  
Volker Bertram

The paper discusses key trends in ship design, ship building and ship operation and extrapolate those trends into the future. Fast and unconventional craft will play a minor role only in this scenario. In fact, trends are towards lower speed and simpler hull shapes, wind assisted technologies and propulsion improving devices. Cleaner fuels, most notably LNG, condition-based maintenance, remote instruction and Augmented Reality will support low-crew ships. The proliferation of sensors and increased satellite bandwidth will fundamentally change logistics.


1992 ◽  
Vol 26 (1) ◽  
pp. 49-63
Author(s):  
Shian Li

British diplomatic contacts with Mao Tze-tung and the communists during the war and immediately after from 1944 to 1946 have remained unresearched by western historians, their significance unrecognized. While Chinese—American relations during the Second World War have attracted wide attention among scholars, many aspects of the Sino-British relationship still remain totally unexamined. This reflects the premise that Britain played only a minor role in shaping Chinese attitudes towards the western powers during the period. In fact, Britain significantly influenced the future of Chinese-Western relations.


2021 ◽  
Vol 72 (1) ◽  
pp. 40-46
Author(s):  
Marina Ruxandra Oțelea ◽  
Dana Mateș ◽  
Agripina Rașcu

Abstract The current pandemic pointed toward a revision of the protection measures against infectious diseases. For any given new pathogen against which human species showed no immunity, isolation and personal protection equipment proved to reduce disease transmission. In medical settings, when there is inevitable contact with infected patients, these preventive measures have undoubtedly change the process of care delivery. The study aims to investigate the opinion of the healthcare workers about the utilization of the personal protective equipment after the pandemic stops. For this purpose, we conducted an online survey about changes related to the COVID-19 pandemic. For the healthcare workers, the survey also included several questions related to personal protective equipment. A total of 512 responders, doctors, and nurses answered to the survey. We performed comparisons between these two categories of personnel using the χ test. Overall, the results show that doctors are keener to follow the recommendations for the personal protective equipment in the future; there was a statistically significant difference (p<0.001) for the usage of gloves and masks while examining febrile patients, and for the handwashing after the examination of each patient. The type of service (outpatient or inpatient procedures) and direct contact with a COVID-19 patient were other factors to modulate the responses regarding using personal protective equipment in the future. The fact that 14.06% of the responders did not consider it necessary to wash hands after examining each patient underlines the urgent need for safety education in all healthcare workers and nurses.


Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.


1958 ◽  
Vol 02 (05/06) ◽  
pp. 462-480 ◽  
Author(s):  
Marc Verstraete ◽  
Patricia A. Clark ◽  
Irving S. Wright

SummaryAn analysis of the results of prothrombin time tests with different types of thromboplastins sheds some light on the problem why the administration of coumarin is difficult to standardize in different centers. Our present ideas on the subject, based on experimental data may be summarized as follows.Several factors of the clotting mechanism are influenced by coumarin derivatives. The action of some of these factors is by-passed in the 1-stage prothrombin time test. The decrease of the prothrombin and factor VII levels may be evaluated in the 1-stage prothrombin time determination (Quick-test). The prolongation of the prothrombin times are, however, predominantly due to the decrease of factor VII activity, the prothrombin content remaining around 50 per cent of normal during an adequate anticoagulant therapy. It is unlikely that this degree of depression of prothrombin is of major significance in interfering with the coagulation mechanism in the protection against thromboembolism. It may, however, play a minor role, which has yet to be evaluated quantitatively. An exact evaluation of factor VII is, therefore, important for the guidance of anticoagulant therapy and the method of choice is the one which is most sensitive to changes in factor VII concentration. The 1-stage prothrombin time test with a rabbit lung thromboplastin seems the most suitable method because rabbit brain preparations exhibit a factor VII-like activity that is not present in rabbit lung preparations.


2016 ◽  
Vol 46 (185) ◽  
pp. 621-638 ◽  
Author(s):  
Christian Siefkes

The ‘Fragment on Machines’ from Marx’s Grundrisse is often cited as an argument that the internal forces of capitalism will lead to its doom. But the argument that the progressive reduction of labor must doom capitalism lacks a proper foundation, as a comparison with the ‘Schemes of Reproduction’ given in Capital II shows. The latter, however, aren’t fully convincing either. In reality, more depends on the private consumption of capitalists than either model recognizes. Ultimately, most can be made of the ‘Fragment on Machines’ by reading it not as an exposure of capitalism’s internal contractions, but as a discussion of a possible communist future where labor (or work) will play but a minor role.


2019 ◽  
Vol 12 (4) ◽  
pp. 311-323 ◽  
Author(s):  
Salvatore Benvenga ◽  
Antonio Micali ◽  
Giovanni Pallio ◽  
Roberto Vita ◽  
Consuelo Malta ◽  
...  

Background: Cadmium (Cd) impairs gametogenesis and damages the blood-testis barrier. Objective: As the primary mechanism of Cd-induced damage is oxidative stress, the effects of two natural antioxidants, myo-inositol (MI) and seleno-L-methionine (Se), were evaluated in mice testes. Methods: Eighty-four male C57 BL/6J mice were divided into twelve groups: 0.9% NaCl (vehicle; 1 ml/kg/day i.p.); Se (0.2 mg/kg/day per os); Se (0.4 mg/kg/day per os); MI (360 mg/kg/day per os); MI plus Se (0.2 mg/kg/day); MI plus Se (0.4 mg/kg/day); CdCl2 (2 mg/kg/day i.p.) plus vehicle; CdCl2 plus MI; CdCl2 plus Se (0.2 mg/kg/day); CdCl2 plus Se (0.4 mg/kg/day); CdCl2 plus MI plus Se (0.2 mg/kg/day); and CdCl2 plus MI plus Se (0.4 mg/kg/day). After 14 days, testes were processed for biochemical, structural and immunohistochemical analyses. Results: CdCl2 increased iNOS and TNF-α expression and Malondialdehyde (MDA) levels, lowered glutathione (GSH) and testosterone, induced testicular lesions, and almost eliminated claudin-11 immunoreactivity. Se administration at 0.2 or 0.4 mg/kg significantly reduced iNOS and TNF-α expression, maintained GSH, MDA and testosterone levels, structural changes and low claudin-11 immunoreactivity. MI alone or associated with Se at 0.2 or 0.4 mg/kg significantly reduced iNOS and TNF-α expression and MDA levels, increased GSH and testosterone levels, ameliorated structural organization and increased claudin-11 patches number. Conclusion: We demonstrated a protective effect of MI, a minor role of Se and an evident positive role of the association between MI and Se on Cd-induced damages of the testis. MI alone or associated with Se might protect testes in subjects exposed to toxicants, at least to those with behavior similar to Cd.


1985 ◽  
Vol 50 (3) ◽  
pp. 581-599 ◽  
Author(s):  
Petr Vaňura ◽  
Emanuel Makrlík

Extraction of microamounts of Sr2+ and Ba2+ (henceforth M2+) from the aqueous solutions of perchloric acid (0.0125-1.02 mol/l) by means of the nitrobenzene solutions of dicarbolide (0.004-0.05 mol/l of H+{Co(C2B9H11)2}-) was studied in the presence of monoglyme (only Ba2+), diglyme, triglyme, and tetraglyme (CH3O-(CH2-CH2O)nCH3, where n = 1, 2, 3, 4). The distribution of glyme betweeen the aqueous and organic phases, the extraction of the protonized glyme molecule HL+ together with the extraction of M2+ ion and of the glyme complex with the M2+ ion, i.e., ML2+ (where L is the molecule of glyme), were found to be the dominating reactions in the systems under study. In the systems with tri- and tetraglymes the extraction of H+ and M2+ ions solvated with two glyme molecules, i.e., the formation of HL2+ and ML22+ species, can probably play a minor role. The values of the respective equilibrium constants, of the stability constants of complexes formed in the organic phase, and the theoretical separation factors αBa/Sr were determined. The effect of the ligand structure on the values of extraction and stability constants in the organic phase is discussed.


Sign in / Sign up

Export Citation Format

Share Document