Overview of research work of Prof. Chu on two medical devices

Impact ◽  
2021 ◽  
Vol 2021 (8) ◽  
pp. 61-63
Author(s):  
Woeichyn Chu
Keyword(s):  
Bone Cement ◽  
Medical Device ◽  
Intramedullary Nailing ◽  
Percutaneous Vertebroplasty ◽  
Research Work ◽  
High Viscosity ◽  
X Ray ◽  
Broken Bones ◽  
Low Viscosity ◽  
Working Together

Surgical procedures are relatively common and procedures for broken bones often involve intramedullary nailing to repair the bone and keep it stable. However, there are challenges associated with the process and Professor Woeichyn Chu, who is a distinguished professor based within the Department of Biomedical Engineering at the National Yang Ming Chiao Tung University in Taiwan, is developing a medical device to help surgeons overcome these challenges, benefiting patients and clinicians. The device is called iMET (intra-medullary endo-transilluminating) and came about after Woeichyn Chu spoke with his brother, Dr William Chu, General Orthopedic Department, Cheng Hsin General Hospital, Taiwan, about some of the challenges relating to intramedullary nailing which led the brothers to begin working together to develop a medical device to help target distal locking holes in intramedullary nailing procedures. The iMET device that the brothers are developing is designed to improve target aiming accuracy and reduce dose absorption concerns. In the process, it will save significant time, effort and money. As well as benefiting patients and clinicians, iMET also reduces X-ray fluoroscopy time, which has health benefits for all involved. Woeichyn Chu and his brother are also developing a device called iKypho, which applies negative pressure during bone cement injection in percutaneous vertebroplasty surgeries. iKypho reduces bone cment leakage risks when using low viscosity cement and reducing the costs associated with high viscosity bone cement.

Percutaneous vertebroplasty with high- versus low-viscosity bone cement for osteoporotic vertebral compression fractures

2020 ◽  
Author(s):  
Feng Miao ◽  
Xiaojun Zeng ◽  
Wei Wang ◽  
Zhou Zhao
Keyword(s):  
Percutaneous Vertebroplasty ◽  
Body Height ◽  
Cement Leakage ◽  
High Viscosity ◽  
Vertebral Compression Fractures ◽  
Vertebral Body Height ◽  
Low Viscosity ◽  
Pain Scores ◽  
Group A ◽  
Group B

Abstract Background: There is no consensus on the best choice between high- and low-viscosity bone cement for percutaneous vertebroplasty (PVP). This study aimed to compare the clinical outcomes and leakage between three cements with different viscosities in treating osteoporotic vertebral compression fractures.Methods: This is a prospective study comparing patients who were treated with PVP: group A (n = 99, 107 vertebrae) with high-viscosity OSTEOPAL V cement, group B (n = 79, 100 vertebrae) with low-viscosity OSTEOPAL V cement, and group C (n = 88, 102 vertebrae) with low-viscosity Eurofix VTP cement. Postoperative pain severity was evaluated using the visual analog scale. Cement leakage was evaluated using radiography and computed tomography.Results: There was no significant difference in the incidence of cement leakage between the three groups (group A 20.6%, group B 24.2%, group C 20.6%, P = 0.767). All three groups showed significant reduction in postoperative pain scores but did not differ significantly in pain scores at postoperative 2 days (group A 2.01 ± 0.62, group B 2.15 ± 0.33, group C 1.92 ± 0.71, P = 0.646). During the 6 months after cement implantation, significantly less reduction in the fractured vertebral body height was noticed in group B and group C than in group A (group A 19.0%, group B 8.1%, group C 7.3%, P = 0.009).Conclusions: Low-viscosity cement has comparable incidence of leakage compared to high-viscosity cement in PVP for osteoporotic vertebral compression fractures. It also can better prevent postoperative loss of vertebral body height.

scholarly journals Unilateral Transforaminal Approach (UTFA) in Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures: A Novel Puncture Technique

2021 ◽  
Author(s):  
wang yefeng ◽  
Li suoyuan ◽  
Cai xiaoqiang ◽  
Shen jun ◽  
Zou tianming
Keyword(s):  
Bone Cement ◽  
Percutaneous Vertebroplasty ◽  
Operation Time ◽  
Vertebral Compression Fractures ◽  
X Rays ◽  
Osteoporotic Vertebral Compression Fractures ◽  
Invasive Treatment ◽  
X Ray ◽  
Compression Fractures ◽  
Transforaminal Approach

Abstract Background: Percutaneous vertebroplasty (PVP) via various puncture approaches was an effective minimally invasive treatment for osteoporotic vertebral compression fractures (OVCFs). In recent years, unilateral puncture techniques had been increasingly used with advantages of shorter operation time, lower X-ray exposure. The aim of this study was to explore the safety and efficacy of the unilateral transforaminal approach (UTFA) in PVP for the treatment of OVCFs. Methods: A retrospective study was designed to review 155 cases of single-level OVCFs from July 2018 to December 2019. We treated 77 patients with PVP via the UTFA and 78 via the bilateral transpedicular approach (BTPA). Operation time, number of intraoperative fluoroscopic X-rays, volume of bone cement injection and distribution of bone cement were recorded. We used Visual Analog Scale (VAS) score and Oswestry disability index (ODI) presurgery and at 1 day, 3 months and last follow-up after surgery to assess clinical outcomes. Results: The operation was successfully completed in both groups, with no complications of neurovascular injuries or bone cement embolism. UTFA group had significantly shorter operation time and less-frequent fluoroscopy than BTPA group (P < 0.05). There were no significant differences between the two groups in volume or distribution of injected bone cement (P > 0.05). Postoperative VAS scores and ODI of the two groups were significantly improved over their presurgical values (P < 0.05), but there were no significant differences in VAS or ODI at each time point between the two groups (P > 0.05). Conclusions: Both unilateral transforaminal PVP and bilateral transpedicular PVP were safe and effective treatments for OVCFs, but the former approach had the advantages of shorter operation time and less X-ray radiation exposure and therefore is worthy of greater clinical application.

Comparison of high- and low-viscosity cement percutaneous vertebroplasty with manipulative reduction for the treatment of Kümmell’s disease: A retrospective cohort study

2021 ◽  
pp. 1-7
Author(s):  
Liang Zhang ◽  
Jingcheng Wang ◽  
Yongxiang Wang ◽  
Xinmin Feng
Keyword(s):  
Clinical Outcomes ◽  
Operative Time ◽  
Percutaneous Vertebroplasty ◽  
Cement Leakage ◽  
High Viscosity ◽  
Vertebral Height ◽  
Low Viscosity ◽  
Significant Difference ◽  
Kummell’S Disease ◽  
Kümmell’S Disease

OBJECTIVE: To compare the clinical outcomes and cement leakage rate between high-viscosity and low-viscosity cement percutaneous vertebroplasty (PVP) with manipulative reduction in the treatment of Kümmell’s disease (KD). METHOD: PVP using high-viscosity cement (Group H) or low-viscosity cement (Group L) with manipulative reduction was compared in 86 KD patients. Visual Analogue Scale (VAS), Oswestry Disability Index (ODI), vertebral height, kyphosis angle and complications were evaluated and compared preoperative, one day postoperative, and at final follow-up. RESULTS: The VAS score, ODI score, mean anterior and middle vertebral height variation significantly improved in both groups postoperatively. However, there was no significant difference between the two groups considering the above results preoperative and postoperative. Significantly less cement leakage (13.6%) and shorter operative time (35.6 ± 5.1 min) were observed in Group H when compared with Group L (45.2% and 41.1 ± 5.3 min) (p< 0.05). CONCLUSION: The clinical outcomes and radiologic findings of PVP with manipulative reduction was not influenced by cement viscosity. However, high cement viscosity PVP was found to be significant less cement leakage and shorter operative time.

Cement pulmonary embolism due to percutaneous vertebroplasty

2020 ◽  
Vol 16 ◽  
Author(s):  
Ali Zohra ◽  
Ugur Gonlugur
Keyword(s):  
Pulmonary Embolism ◽  
Foreign Body ◽  
Bone Density ◽  
Conservative Treatment ◽  
Bone Cement ◽  
Percutaneous Vertebroplasty ◽  
Pulmonary Arteries ◽  
Potential Complication ◽  
X Ray ◽  
Chest X Ray

Background: : Bone cement is uncommon cause of foreign-body pulmonary embolism. Discussion:: 65-year-old woman with a wheeze presented with multiple linear opacities with bone density on chest x-ray. She reported a percutaneous vertebroplasty 4 months ago. Non-contrast chest computerized tomography showed peripheral cement emboli in pulmonary arteries. The patient received conservative treatment. Conclusion: Clinicians should be aware of this potential complication following vertebroplasty. It is necessary to perform a chest x-ray after procedure.

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