Conservation Of Symphytum Officinale L. At Cmprh Garden, Emerald

Symphytum L. commonly called as comfrey, belongs to the family Boraginaceae. The genus of Symphytum L. have a great medicinal value and used to treat a wide variety of ailments viz., bronchial problems, sprains, broken bones, arthritis, acne and skin conditions whereas pharmacological effects of comfrey extracts are endorsed to several chemical compounds. In view of above point, the present study of Survey, Collection and Documentation of Symphytum species, were carried out in different places of India. The rhizomes of Symphytum species were collected from Mynala village of Nilgiris, subsequent survey were carried out to IIIM Chatha Research Farm Jammu Tawi during 2017-2018 and it was grown at CMPRH garden, Emerald to confirm the identification of plants species. This specimen was collected and preserved herbarium at CMPRH garden Emerald for future reference. Among plants parts roots and leaves are mostly used for homeopathic system of medicine and this species were maintained and reproduces subsequent year by seed and root fragments. Root cuttings are the least expensive method of propagation. In addition to that Performance of Symphytum officinale at Nilgiris conditions were observed and the results revealed that Symphytum officinale L. is an erect, perennial herb with thick root stock. Leaves oblong-lanceolate and flowers are blue in colour. The data on length of root ranged from 10-20 cm with black to brown colour. Similarly, the length of lower, middle and upper cauline leaves ranged from 32.3-37.2 cm, 25.2-27.8cm, 10.4- 13.2cm, respectively Whereas the width of the lower, middle, upper leaves ranged 12.5-17.4 cm , 7.6- 10.2cm , 3.4-4.1cm, respectively. Further, the studies on Symphytum officnale regarding root yield, dry matter ratio of leaves and roots as well as physiochemical properties other chemical compounds present and uses in homoeopathic system of the medicine under the Nilgiris condition are need to be studied elaborately in future.

Prapration of Tablet from Pencil Cactus for Treatment of Piles by Direct Compression method

The intention of current review is to make available upto-date information on morphology, ecological biodiversity, medicinal uses, phytochemistry and pharmacological activities on different parts of Euphorbia tirucalli (E. tirucalli). This plant has a number of medicinal uses. Latex of E. tirucalli is vesicant and rubefacient which is used for rheumatism, warts, cough, asthma, ear-ache, tooth-ache and neuralgia. It acts as a purgative in small doses while in big doses it is bitter irritant and emetic. Milky juice is alexiteric, carminative and purgative. It is useful in whooping cough is used in treatment of piles. gonorrhea, asthma, leprosy, dropsy, dyspepsia, enlargement of spleen, colic, jaundice and stone in bladder. The fresh milky juice is good alternative in syphilis and a good application in neuralgia. A decoction of branches is used in gastralgia and colic. Bark is used in treatment of fractures. Poultices prepared from the stem are useful to repair the broken bones. Boiled root liquid acts as an emetic in cases of snake-bite and for infertility in women. The wood is used for rafters, toys and veneering purposes. It is also useful against leprosy and foot paralysis subsequent to childbirth. E. tirucalli is reported to have euphol, β-sitosterol, euphorbol hexacosonate, cycloeuphordenol, cyclotirucanenol, tirucalicine, tri-methyl ellagic acid, gallic acids, terpenic alcohol. genotoxic/mutagenic, hepatoprotective, insect repellants, immunomodulatory, larvicidal, molluscicidal/ovicidal/piscicidal, myelopoiesis, proteolytic/chitinolytics pharmacological activities. There is a need to isolate dynamic constituents, their biological trial, molecular mechanisms, experimental protection and legalization of therapeutic uses of E. tirucalli. The collected information will be helpful to locate up study protocol for expansion in curative and treat a variety used in treatment of piles., isoeuphorol, taraxasterol, tirucallol, euphorone, euphorcinol, euphorbins, 12-deoxy4βhydroxyphorbol-13-phenyl acetate-20-acetate, 12, 20- dideoxyphorbol-13-isobutyrate, glut-5-en-3-β-ol, 3,3′- diO-methylellagic acid, euphorbin-A (polyphenol), tirucallin-A (7) (tannin), tirucallin-B (11), euphorbin-F (14) (dimers), cycloartenol, 24- methylenecycloartenol, ingenol triacetate, 12-deoxy-4β-hydroxyphorbol- 13- phenyl acetate-20-acetate, taraxerone, euphorginol, taraxerol, campesterol, stigmasterol, palmitic acid, linoleic acid, β-amyrin, etc. Active phytoconstituents. E. tirucalli have possessed activity in humanly mphocytes, analgesic, anthelmintics, antiarthritic, antibacterial/antifungal/antimicrobial Antihemerrhoids. Keywords: Euphorbia tirucalli Morphology Ecological biodiversity Medicinal uses Phytochemistry Anticance antihemerrhoids

Survival of femur fractures in wild stoats (Mustela erminea)

Stoats (Mustela erminea) are active hunters and, therefore, one might predict that any broken bones or other injuries impeding active movement would incur a serious risk of starvation. Dead stoats (n = 560) were collected from trappers operating predator control lines in three conservation areas of New Zealand from 1972–1978. Femurs were cleaned and examined for healed injuries and deformities. Five femurs from four stoats (one with both femurs injured) showed traumatic distortions following healing of complete breaks incurred during life. A further case recorded during post-eradication monitoring in 2010 on Rangitoto, an offshore island, is added. These data provide evidence that wild stoats have a remarkable capacity to tolerate catastrophic femur fractures. They can survive long enough, despite the implied limitation to their energetic hunting style, to permit full healing even though the result is a gross distortion of the femoral shaft.

Overview of research work of Prof. Chu on two medical devices

Surgical procedures are relatively common and procedures for broken bones often involve intramedullary nailing to repair the bone and keep it stable. However, there are challenges associated with the process and Professor Woeichyn Chu, who is a distinguished professor based within the Department of Biomedical Engineering at the National Yang Ming Chiao Tung University in Taiwan, is developing a medical device to help surgeons overcome these challenges, benefiting patients and clinicians. The device is called iMET (intra-medullary endo-transilluminating) and came about after Woeichyn Chu spoke with his brother, Dr William Chu, General Orthopedic Department, Cheng Hsin General Hospital, Taiwan, about some of the challenges relating to intramedullary nailing which led the brothers to begin working together to develop a medical device to help target distal locking holes in intramedullary nailing procedures. The iMET device that the brothers are developing is designed to improve target aiming accuracy and reduce dose absorption concerns. In the process, it will save significant time, effort and money. As well as benefiting patients and clinicians, iMET also reduces X-ray fluoroscopy time, which has health benefits for all involved. Woeichyn Chu and his brother are also developing a device called iKypho, which applies negative pressure during bone cement injection in percutaneous vertebroplasty surgeries. iKypho reduces bone cment leakage risks when using low viscosity cement and reducing the costs associated with high viscosity bone cement.

IMPROVING KNOWLEDGE OF ONLINE MOTORCYCLE TAXI DRIVERS (OJOL) ABOUT EMERGENCY MANAGEMENT OF FRACTURES WITH SPLINTS ON THE ROAD

The incidence of fractures is the highest prevalence in the world. Fractures by accidents require serious management to prevent serious injuries. The improper first treatment of fracture victims can lead to death and disability. The causes of fractures in Indonesia include traffic accidents. The number of motorized vehicles in Indonesia is increasing by 119.560 cases every year which caused new problems, including security, safety, and traffic congestion. Online motorcycle taxis are alternative public transportation because they can reach places that are not passed by other public transportation. Online motorcycle taxis riders are people who are often on the road and often see even as victims of broken bones from traffic accidents, so there is a need for counseling and handling emergency conditions for motorcycle taxi drivers on the road. This community service activity aimed to increase the ojol drivers’ knowledge and ability in dealing with emergency fractures on the road using discussion methods. The activity was carried out on Thursday, July 16, 2020, carried out face-to-face in the Sukoharjo Regency pavilion, followed by a number of 20 participants. The result of this activity found an increase in the knowledge of ojol drivers by 40% with posttest results of 80% continued with splint dressing. The results of these activities were followed up by coordination with Gojek for greater community service.

How Do Broken Bones Heal?

The human skeleton is truly amazing. It is a moving frame that protects soft tissues and organs, while simultaneously storing minerals and producing blood cells and immune cells. Bones also have an amazing ability to rebuild and repair themselves. There is no need to worry much if you break a bone because, with the support of your doctors and therapists, the bone should heal itself. Bones have a flexible structure that serves as the scaffolding for the minerals that create a strong and stable skeleton. Unfortunately, bone strength may decrease with age or due to food or hormonal deficiencies. When you experience pain, swelling, or bruising following a fall, you should go to the doctor to see if you have a bone fracture. But do not worry—remember that bones can repair themselves! Have you ever wondered how bone healing happens? You can find the answers in this article.

CHARACTERISTICS OF PATIENTS WITH BRAIN INJURY DUE TO LAND TRAFFIC ACCIDENTS TREATED AT NINH BINH PROVINCIAL GENERAL HOSPITAL IN 2018

This was an epidemiological study through a retrospective review of 215 medical records of patients with brain injury due to land traffic accidents treated at Ninh Binh Provincial General Hospital. Theresults showed that the majority of research subjects were male, accounting for 80.5%; The age group with higher prevalence of accidents was under 30 years old, accounting for 31.2%; The agegroup of 50-59 years old was at lower prevalence of accidents accounting for 15.8%. The time of the higher chance of occurring accident was between 4p.m and 11p.m daily. The majorityof traffic accidents occurred when riding motorbikes and electric bicycles (82.3%). About 75.0% of the victims received first aid with a gauze bandage; 5.4% of them had broken bones fixed. Amongthe brain injuries, 34.4% of the victims suffered from frontal trauma; 29.3% had unilateral cerebral hemisphere injury, 24.2% had temporal region injury, 15.8% had occipital region injury, and 8.4% ofvictims had parietal injury. More than half of the study subjects (53.5%) were hospitalized for 7-10 days. The rate of patients who have been discharged from the hospital with improved symptoms was81.4%; and 14.9% of patients were transferred to higher level hospitals.

Longitudinal cohort study of injury type, settings, treatment and costs in British Columbia youth, 2003–2013

BackgroundIn 2010 in British Columbia (BC), Canada, total injury costs per capita were higher among youth aged 15–24 years than in any other age group. Injury prevention efforts have targeted injuries with high mortality (transportation injuries) or morbidity (concussions). However, the profile and health costs of common youth injuries (types, locations, treatment choices and prevention strategies) and how these change from adolescence to young adulthood is not known.MethodsParticipants (n=662) were a randomly recruited cohort of BC youth, aged 12–18, in 2003. They were followed biennially across a decade (six assessments).ResultsSerious injuries (defined as serious enough to limit normal daily activities) in the last year were reported by 27%–41% of participants at each assessment. Most common injuries were sprains or strains, broken bones, cuts, punctures or animal bites, and severe bruises. Most occurred when playing a sport or from falling. Estimated total direct cost of treatment per injury was approximately $2500. In addition, 25% experienced serious injuries at three or more assessments, indicating possible differences that warrents further investigation.ConclusionsThe occurence and health cost of common injuries to youth and young adults are underestimated in this study but are nevertheless substantial. Ongoing surveillence, awareness raising, and prevention efforts may be needed to reduce these costs.

Effect of Combined Extracts of Mummy, Withania Coagulans, and Turmeric on the Repair and Treatment of Bone Fractures in Rats

Background: Repair of broken bones due to physiological or pathological factors has always been important for researchers. In this regard, this study aimed to evaluate the effect of a combined extract on the osteogenic process in the experimental fracture created in the femoral of rats as laboratory models. Materials and Methods: This experimental study was performed on 21 rats. After induction of general anesthesia to each mouse, a 3-cm incision was made in the femoral bone and it was broken with a special hammer. After surgery, the control group did not receive any extract, while the three experimental groups received 200, 500, and 1000 mg/kg PO, respectively. In the next step, 21 days after surgery, euthanasia was performed and bone sections were prepared and stained in the fracture site. Next, histopathological and histomorphometric studies were carried out for the evaluation of bone healing in rats. The collected data were analyzed in SPSS software (version 21). Results: According to the pairwise comparison test, the mean difference of variables, namely bone marrow, woven bone, and lamellar bone of the third group of the test was significantly different from those of the other groups (P<0.05). This indicated that receiving the extract in the experimental groups with an increased dose led to a decrease in the mean bone marrow and woven bone which, in turn, increased the mean lamellar bone. Conclusion: The results showed that the combined extracts of mummy, Withania coagulans, and turmeric can stimulate osteogenesis in rats and be considered as a candidate for fracture treatment.

Numerical Analysis of SS316L Biaxial Cruciform Specimens Under Proportional Loading Paths

In this paper, finite element analyses were conducted to investigate the stress and strain states resulting from varying the deformation of stainless steel 316L under biaxial loading. To that end, a biaxial specimen geometry was designed in collaboration with the US National Institute of Standards and Technology (NIST) to achieve large and uniform strain values in the central pocket region. Special care was taken to ensure that the specimen design could be readily manufactured with available resources. Simultaneously, the specimen design criteria required an acceptable strain uniformity in a sufficiently large pocket section to allow for accurate deformation and austenite to martensite phase fraction measurements. This demonstrates the concept of altering the final material properties through stress superposition. Numerical results show that nearly linear curves were observed in the strain path plots. The minimum uniform deformation area for the 4:1 case had a radius of ∼1 mm, which is sufficient for experimental analyses, e.g., digital imaging correlation and electron beam backscatter diffraction. As an application for such heterogeneous materials, patient specific trauma fixation hardware, which are surgically implanted to set broken bones during healing, require high strength in areas where screws are located, i.e., martensite phase, yet low weight elsewhere.