scholarly journals Effects of the Unpleasant Symptom-Relief Program on Preterm Labor Stress, Anxiety, Physical Discomfort, and Situational Discomfort among Hospitalized High-Risk Pregnant Women: A Nonrandomized Controlled Trial

2021 ◽  
Vol 25 (4) ◽  
pp. 269-281
Author(s):  
Guy Nam Kim ◽  
Eun-Young Jun
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Repeated Measures ◽  
Preterm Labor ◽  
Symptom Relief ◽  
T Test ◽  
Control Group ◽  
Physical Discomfort ◽  
Labor Stress ◽  
Relief Program

Purpose: This study aimed to develop and evaluate the effects of the Unpleasant Symptom-Relief Program to mitigate preterm labor stress, anxiety, physical discomfort, and situational discomfort in hospitalized high-risk pregnant women.Methods: This study used a nonequivalent control group nonsynchronized design and analyzed 23 participants from the experimental group and 23 from the control group. The participants from both the groups were matched and diagnosed with preterm labor, incompetent internal os of the cervix, preterm premature rupture of membrane, placenta previa, or gestational diabetes mellitus. The effects of the Unpleasant Symptom-Relief Program were measured using tools such as preterm labor stress, anxiety, physical discomfort, and situational discomfort. The data were analyzed with IBM SPSS Statistics ver. 21.0 using descriptive statistics, t-test, chi-square test, paired t-test, and repeated measures analysis of variance.Results: The Unpleasant Symptom-Relief Program was effective in reducing preterm labor stress (F= 8.24, p=0.001), anxiety (F=17.80, p≤0.001), and situational discomfort (F=5.95, p=0.004). However, it was not effective in reducing the physical discomfort (F=1.20, p=0.311). Post hoc analysis between time points revealed effective reduction in the preterm labor stress and anxiety in both the groups immediately after the end of the program and at 7 days after the program. Situational discomfort was reduced at 7 days after the end of the program in both the groups.Conclusion: The Unpleasant Symptom-Relief Program can be applied in practice by nurses. It can contribute to alleviating the symptoms and discomfort of high-risk pregnant women.

PENGARUH PEMBERIAN JUS ALPUKAT (PERSEA AMERICANA [MILL]) TERHADAP PENINGKATAN KADAR HEMOGLOBIN DAN JUMLAH ERITROSIT IBU HAMIL

2018 ◽  
Vol 6 (1) ◽  
pp. 55
Author(s):  
Feriyal Salim Bawazir
Keyword(s):  
Experimental Design ◽  
Pregnant Women ◽  
Repeated Measures ◽  
Intervention Group ◽  
Persea Americana ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Paired Sample ◽  
Quasi Experimental

Anemia terjadi di seluruh dunia, terutama di negara berkembang dan pada kelompok sosio-ekonomi rendah, yaitu pada 45 % wanita. Anemia merupakan salah satu penyebab tidak langsung kematian ibu. Berbagai upaya dilakukan, namun belum menunjukkan hasil maksimal. Perlu upaya lain berupa pemberian jus alpukat untuk mengatasi anemia kehamilan. Penelitian ini bertujuan mengetahui pengaruh pemberian jus alpukat terhadap kadar hemoglobin dan jumlah eritrosit ibu hamil. Jenis penelitian Quasi experimental design, dilaksanakan bulan November s.d. Desember 2017 di Puskesmas Sindang. Jumlah responden 33 ibu hamil trimester II, kadar Hb < 11 g/dL ditentukan dengan purposive sampling. Responden mengisi kuesioner, kemudian dilakukan pemeriksaan kadar Hb dan jumlah eritrosit 3 kali yaitu pre, hari ke-7, dan 14 setelah intervensi. Analisis data dilakukan secara deskriptif, analisis bivariat menggunakan independent dan paired sample t-test serta analisis mulitivariat menggunakan repeated measures ANOVA. Mengonsumsi jus alpukat selama 14 hari efektif meningkatkan kadar Hb dan jumlah eritrosit. Hasil uji beda tidak terdapat perbedaan kadar Hb dan jumlah eritrosit antara kelompok kontrol dengan intervensi. Hb rata-rata kelompok kontrol 10,375 g/dL sedangkan intervensi 10,653 g/dL (nilai p=0,986). Jumlah eritrosit rata-rata pada kelompok kontrol yaitu 3,455 juta/mm3 sedangkan intervensi 3,614 juta/mm3 (nilai p=0,763). Uji multivariat terlihat perbedaan antara kelompok kontrol dengan intervensi. Pada kelompok kontrol kadar Hb rata-rata (p=0,441) sedangkan intervensi (p=0,023). Untuk jumlah eritrosit rata-rata pada kelompok kontrol (p=1,000) sedangkan intervensi (p=0,043). Simpulan peneltian adalah terdapat pengaruh positif pemberian jus alpukat selama 14 hari terhadap peningkatan kadar Hb dan jumlah eritrosit rata-rata, namun tidak ada perbedaan antara kelompok intervensi dan kelompok kontrol. Abstrak Anemia occurs worlwide, especially in developing countries and in low socioeconomic groups. i.e. in 45% of women. Anemia is one of the causes of bleeding. Various attempts have been made, but have not shown the maximum results. Need other efforts in the nutrition form of avocado juice to overcome the anemia of pregnancy. This research aims to determine the effect of avocado juice on hemoglobin and erythrocyte levels of pregnant women. The type of this research is Quasi Experimental design which implemented in November to December 2017 with 33 respondents of trimester II pregnant women who have HB<11g/dL and determined by purposes sampling. Repondents filled out questionnaires to determine their characteristics and performed laboratorium checkup 3 times, pre, on day 7 and 14 after intervention. The data analysis was done descriptively, hypothesis testing using independent sample t-test, to know the effectiveness of avocado juice using paired sample t-test and to know the difference of mean of Hb and erythrocytes using ANOVA repeated measures test. Consuming avocado juice for 14 days was effective in increasing the average of Hb and erythrocyte levels. LSD post hoc test results showed significant differences in Hb and erythrocytes mean (Hb p-value = 0.023 and erythrocytes p-value = 0.043) in the intervention group between pre and day 14 post intervention. While in the control group p-value p= 0.441 for Hb and erythrocytes p=1.000. The conclusion of this research that there was a positive effect of consuming avocado juice for 14 days in increasing the average of Hb and erythrocyte levels, but the hypothesis test result showed that there was no significant difference between the intervention group and the control group.

INOVASIA Study: A Randomized Open Controlled Trial to Evaluate Pravastatin to Prevent Preeclampsia and its Effects on sFlt1/PLGF Levels

2021 ◽  
Author(s):  
Muhammad Ilham Aldika Akbar ◽  
Angelina Yosediputra ◽  
Raditya Eri Pratama ◽  
Nur Lailatul Fadhilah ◽  
Sulistyowati Sulistyowati ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Controlled Trial ◽  
Intervention Group ◽  
Perinatal Outcomes ◽  
Neonatal Morbidity ◽  
Clinical Risk Factor ◽  
Control Group ◽  
Significant Deterioration ◽  
Plgf Ratio

Objectives To evaluate the effect of pravastatin to prevent preeclampsia (PE) in pregnant women at a high risk of developing preeclampsia and the maternal and perinatal outcomes and the sFlt1/PLGF ratio. Study Design This is an open labelled RCT part of INOVASIA trial. Pregnant women at a high risk of developing PE were recruited and randomized into an intervention group (40) and a control group (40). The inclusion criteria consisted of pregnant women with positive clinical risk factor and abnormal uterine artery doppler examination at 10-20 weeks gestational age. The control group received low dose aspirin (80 mg/day) and calcium (1 g/day), while the intervention group received additional pravastatin (20 mg twice daily) starting from 14-20 weeks gestation until delivery. Research blood samples were collected before the first dose of pravastatin and before delivery. The main outcome was the rate of maternal preeclampsia, maternal-perinatal outcomes, and sFlt-1, PLGF, sFlt-1/PlGF ratio and sEng levels. Results The rate of preeclampsia was (non-significantly) lower in the pravastatin group compared with the control group (17.5% vs 35%). The pravastatin group also had a (non-significant) lower rate of severe preeclampsia, HELLP syndrome, acute kidney injury and severe hypertension. The rate of (iatrogenic) preterm delivery was significantly (p=0.048) lower in the pravastatin group (n=4) compared with the controls (n=12). Neonates in the pravastatin group had significantly higher birthweights (2931 + 537 vs 2625 + 872 g; p=0.006), lower Apgar scores < 7 (2.5 vs 27.5%, p=0.002), composite neonatal morbidity (0 vs 20%, p=0.005) and NICU admission rates (0 vs 15%, p=0.026). All biomarkers show a significant deterioration in the control group compared with non significant changes in the pravastatin group. Conclusions Pravastatin holds promise in the secondary prevention of preeclampsia and placenta-mediated adverse perinatal outcomes by improving the angiogenic imbalance.

scholarly journals THE EFFECT OF RECTAL PROGESTERONE ON DOPPLER PARAMETERS OF THE UTERINE ARTERIES FOR THE PREVENTION OF PRETERM DELIVERY IN IRAQI POPULATION

2018 ◽  
Vol 11 (10) ◽  
pp. 545
Author(s):  
Fatin Shallal Farhan ◽  
Ban Hadi Hameed ◽  
Muna Abdulghani Zghair
Keyword(s):  
Pregnant Women ◽  
Preterm Labor ◽  
Resistance Index ◽  
Control Group ◽  
Study Group ◽  
Duration Of Treatment ◽  
Uterine Arteries ◽  
Doppler Study ◽  
Threatened Preterm Labor ◽  
Doppler Indices

Objective: The effectiveness of progesterone in the prevention of threatened preterm labor has been established for many years, but the preferable route, dose, and duration of treatment are until now under the evaluation of researches. The aim of this study was to determine the effect of rectal progesterone on Doppler indices of the uterine arteries in pregnant women with threatened preterm delivery.Methods: A prospective case–control study was conducted at the obstetric ward and the Outpatients Department of Al-Yarmouk Teaching Hospital in Baghdad for the period of 1 year from April 1, 2017, to April 1, 2018. 100 women were enrolled in the study, 50 of them were pregnant women with a diagnosis of preterm labor assigned as a study group and the other 50 were apparently healthy pregnant women of the same gestational age assigned as a control group. Doppler study of uterine arteries was done to all participants, and the results were compared for both groups. The patients with preterm labor received nifedipine tocolysis initially until contractions subsided and Doppler study had been repeated for those women after 1 week of rectal progesterone therapy.Results: The study group had a significantly higher resistance index (RI) than the control group (0.58 vs. 0.52) as p<0.05, in spite of the pulsatility index (PI) being higher for the study group compared to the control group (0.78 vs. 0.77) but this difference was not statistically significant. The RI before the therapy (0.58) was significantly higher than the index after therapy (0.52), and the PI was again significantly higher before therapy (0.78) than after therapy (0.71) as p<0.05. During the follow-up period, 3 (6.5%), 4 (8.7), and 39 (84.8%) patients delivered within 1 week, after 1 week, and at term, respectively.Conclusion: Rectal progesterone can arrest threatened preterm labor, and this effect is possible in part explained by its action on uterine arteries.

scholarly journals Peculiarities of pregnansy and childbirth in patients with a burdened gynecological anamnesis

2020 ◽  
Vol 5 ◽  
pp. 5-10
Author(s):  
T. P. Andriichuk ◽  
A. Ya. Senchuk ◽  
V. I. Chermak
Keyword(s):  
Retrospective Study ◽  
High Risk ◽  
Pregnant Women ◽  
Postpartum Period ◽  
Control Group ◽  
Careful Monitoring ◽  
Pregnancy And Childbirth ◽  
History Of ◽  
High Level ◽  
Adaptive Reactions

The objective: to study the features of pregnancy, childbirth, postpartum period, fetal status and newborns in patients with a history of chronic salpingo-оophoritis.Materials and methods. Conducted a retrospective study of 150 birth histories and neonatal development maps. All patients were divided into two groups. The main group includes 100 patients with chronic salpingo-оophoritis, for which they received anti-inflammatory treatment from 1 to 3 times before pregnancy. The control group included 50 pregnant women who did not suffer from chronic salpingo-оophoritis.Results. Our analysis of pregnancy, childbirth, fetal and neonatal status in women with chronic salpingo-оophoritis indicates that such patients have a complicated obstetric and gynecological and somatic history, which forms an unfavorable basic condition of organs and systems, imperfect adaptation to pregnancy, high risk of failure of adaptive reactions. The result is a violation of the formation and development of the mother-placenta-fetus system and, as a consequence, a high level of complications during pregnancy, childbirth and perinatal pathology.Conclusion. Patients suffering from chronic salpingo-oophoritis should be considered at high risk of possible complications during pregnancy and childbirth. This category of women needs quality preconception training and careful monitoring during pregnancy.

scholarly journals PENINGKATAN KADAR HEMOGLOBIN (Hb) PADA IBU HAMIL DENGAN ANEMIA DENGAN KONSUMSI JUS JAMBU BIJI (PSIDIUM GUAJAVA. L )

2021 ◽  
Vol 7 (1) ◽  
pp. 109-115
Author(s):  
Neneng Siti Lathifah ◽  
Zarma H ◽  
Nurul Isnaini
Keyword(s):  
Pregnant Women ◽  
Health Center ◽  
Psidium Guajava ◽  
Hemoglobin Level ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Equivalent Control ◽  
Average Hemoglobin

IMPROVEMENT OF HEMOGLOBIN (Hb) LEVELS IN PREGNANT WOMEN WITH ANEMIA WITH THE CONSUMPTION OF JAMBU SEEDS (PSIDIUM GUAJAVA. L) ABSTRACT Background Anemia in pregnancy is a national problem because it reflects the socio-economic condition of the community and its influence is very large on the quality of human resources. The incidence of anemia in pregnant women 2018 in Pesisir Barat Regency is 29.9%. The incidence of anemia in pregnant women at Krui Health Center is 67.5%. The purpose of this study is to know the effect of giving guava juice (Psidium Guajava. L) to the increase of hemoglobin (Hb) levels in pregnant women with anemia in Krui health center in 2019.Methods Quantitative Research Type, the research design is a quasi-experimental method with a Non-equivalent Control Group Design approach. The population in this study were as many as 60 second trimester pregnant women and third trimester who had anemia, a sample of 30 pregnant women. 15 people were given treatment with guava fruit juice and Fe tablets, and 15 people were given treatment with Fe tablets, with inclusion criteria Willing to be respondents, Willing to consume guava juice, Pregnant women with mild and moderate anemia with hemoglobin levels (Hb 7.9 - 10 g / dl). With purposive sampling sampling technique. Analyze data with T-test (univariat and bivariat).The results showed an average hemoglobin level before consumption of guava juice and Fe tablets of 9.72 gr / dl, the average hemoglobin level after consumption of guava juice and Fe tablets was 11.13 gr / dl, the average hemoglobin level before consumption of Fe tablets of 9.80 gr / dl, the average hemoglobin level after consumption of FE tablets was 10.60 gr / dl. Conclusion It was known that there was an effect of giving guava juice (Psidium Guajava. L) to Hb levels in pregnant women with anemia in Krui Public Health Center, West Coast District in 2019. The results of the t test were p value 0,000 <α (0.05).Suggestion  It is recommended for health workers, especially midwives, to encourage pregnant women to consume guava juice as a companion to Fe because it can raise hemoglobin levels in pregnant women. Keywords              : Guava Juice, Tablets Fe, Hemoglobin Level ABSTRAK Latar Belakang Anemia pada kehamilan merupakan masalah nasional karena mencerminkan keadaan sosial ekonomi masyarakat dan pengaruhnya sangat besar terhadap kualitas sumber daya manusia. Angka kejadian anemia pada ibu hamil tahun 2018 di Kabupaten Pesisir Barat adalah sebesar 29,9%. Angka kejadian anemia pada ibu hamil di Puskesmas Krui sebesar 67,5%.Tujuan dari penelitian ini adalah diketahui Pengaruh Pemberian Jus Jambu Biji (Psidium Guajava. L) Terhadap Peningkatan Kadar Hemoglobin (Hb) pada Ibu Hamil dengan Anemia di Puskesmas Krui Tahun 2019.Metode Jenis Penelitian Kuantitatif, rancangan penelitian metode quasi eksperimen dengan pendekatan Non-equivalent Control Group Design. Populasi dalam penelitian ini adalah sebanyak 60 orang ibu hamil trimester II dan trimester III yang mengalami anemia, Sampel sebanyak 30 ibu hamil. 15 orang diberikan perlakuan dengan jus jambu biji dan tablet Fe, dan 15 orang diberikan perlakun dengan tablet Fe, dengan kriteria inklusi Bersedia menjadi responden, Bersedia mengkonsumsi jus jambu biji, Ibu hamil dengan anemia ringan dan sedang dengan kadar hemoglobin (Hb 7,9 – 10 g/dl). Dengan teknik sampling purposive sampling. Analisa data dengan uji T-test (univariat dan bivariat).Hasil penelitian menunjukan rata-rata kadar hemoglobin sebelum konsumsi jus jambu biji dan tablet Fe sebesar 9,72 gr/dl, rata-rata kadar hemoglobin setelah konsumsi jus jambu biji dan tablet Fe sebesar 11,13 gr/dl, rata-rata kadar hemoglobin sebelum konsumsi tablet Fe sebesar 9,80 gr/dl, rata-rata kadar hemoglobin setelah konsumsi tablet Fe sebesar 10,60 gr/dl.Kesimpulan Diketahui Ada Pengaruh Pemberian Jus Jambu Biji (Psidium Guajava. L) Terhadap Kadar Hb pada Ibu Hamil dengan Anemia di Puskesmas Krui Kabupaten Pesisir Barat Tahun 2019. Hasil uji t didapat p value 0,000 < α (0,05).Saran bagi tenaga kesehatan khususnya bidan agar menganjurkan kepada ibu hamil untuk mengkonsumsi jus jambu biji sebagai pendamping Fe karena dapat menaikkan kadar hemoglobin pada ibu hamil. Kata Kunci            : Jus Jambu Biji, Tablet Fe, Kadar hemoglobin

scholarly journals The Effects of a Support Program for Family Caregivers of Elderly with Dementia on Empowerment and Attitudes toward Dementia

2019 ◽  
Vol 25 (1) ◽  
pp. 103-114 ◽  
Author(s):  
So Yoon Kim ◽  
Seonghee Jeong
Keyword(s):  
Family Caregivers ◽  
Repeated Measures ◽  
T Test ◽  
Support Program ◽  
Support Programs ◽  
Control Group ◽  
Exact Probability ◽  
Family Empowerment ◽  
Post Test ◽  
And Control

Purpose: This research was conducted to identify the effects of providing support programs to families of elderly with dementia on family empowerment and attitudes toward dementia. Methods: A nonequivalent control group pre- and post-test design was used. Participants were 49 family caregivers, experimental (24) and control (25), recruited from families through a dementia support center in Y district. This program implemented Haearim, a support program for family caregivers of demented elders developed by the National Institute of Dementia in 2016. Outcome measures were empowerment and attitudes toward to dementia. Data were analyzed with a ${chi}^2-test$, independent t-test, Fisher's exact probability test, paired t-test, and repeated measures ANOVA with SPSS/PC version 20.0. Results: Family empowerment (F=6.84, p=.002) and family caregivers' attitudes (F=16.48, p<.001) toward dementia in the experimental group improved significantly more than that of the control group after intervention. Conclusion: Results indicate that support programs for families of elderly with dementia are effective in positively changing empowerment and attitudes toward dementia among family caregivers.

Великі акушерські синдроми – сучасні можливості профілактики

2018 ◽  
pp. 67-72
Author(s):  
T.G. Romanenko ◽  
◽  
O.M. Sulimenko ◽  
Keyword(s):  
Statistical Analysis ◽  
High Risk ◽  
Pregnant Women ◽  
Fetal Distress ◽  
Placental Insufficiency ◽  
Control Group ◽  
Fetal Growth Retardation ◽  
Prophylactic Measures ◽  
Pathological Pregnancy ◽  
Micronized Progesterone

The objective: was to reduce the incidence and severity of the development of «Great Obstetrical Syndromes»: miscarriage of pregnancy, placental insufficiency, fetal growth retardation and / or fetal distress, preeclampsia, premature detachment of a normally located placenta, premature delivery, by developing an algorithm for prophylaxis during pregnancy in women at high risk for their development. Materials and methods. Clinical and statistical analysis of pregnancy in 88 pregnant women with high risk of decompensation of placental insufficiency was conducted. Depending on the method of preventing complications, 2 groups were formed. The I group included 58 pregnant women who were offered the following algorithm: micronized progesterone 200 mg PV from 6 to 20 weeks of gestation; from 21 to 26 weeks of gestation and from 31 to 36 weeks; phleboprotector with ultra-micronized fractions of bioflavonoids (Flego) 15 ml per os; with subsequent appointment from 21 to 26 weeks of gestation; and from 31 to 36 weeks. Group II included 30 pregnant women who had abandoned any proposed prophylactic measures. The control group consisted of 30 healthy pregnant women. Clinical and statistical analysis of pregnancy in the study groups was conducted. During statistical processing, personal computer and software Microsoft Excel XP and Statistica 6.0 Windows, methods of descriptive statistics, correlation analysis were used. The reliability of the difference between the indicators is estimated by the Student-Fisher criterion. Results. The method of prophylaxis of «Great Obstetrical Syndromes» by sequential administration from the early stages of pregnancy of micronized progesterone with the following appointment – from the second trimester of pregnancy – showed a high efficacy of the phleboprotector, which is manifested in a significantly lower number of cases of preeclampsia in the main group of 3.5% (2) versus 50% (15) in the control group, placental insufficiency was 13.8% (8) versus 100% (30); fetal growth retardation was 5.2% (3) versus 56.7% (17); fetal distress was 3.5% (2) versus 43 , 3% (13), preterm labor 1.7% (1) versus 13.3% (4) and in the absence of premature detachment normal but located on the placenta, severe forms of preeclampsia and placental insufficiency. Conclusions. Pregnant of «Great Obstetrical Syndromes» risk groups need timely prophylactic measures to reduce the likelihood of a pathological pregnancy and improve perinatal outcomes. The proposed prophylaxis scheme significantly lowered the incidence of large obstetric syndromes and improved neonatal outcomes. Key words: great obstetrical syndromes, pathological pregnancy, placental dysfunction, phleboprotector.

Mean Platelet Volume is Affected in Term Fetuses with Intrauterine Growth Restriction

2020 ◽  
Author(s):  
Gul Nihal Buyuk ◽  
Z.Asli Oskovi-Kaplan ◽  
Aysegul Oksuzoglu ◽  
H.Levent Keskin
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Mean Platelet Volume ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Control Group ◽  
Platelet Volume ◽  
Intrauterine Growth ◽  
Potential Marker ◽  
The Mean

Abstract Objectives The aim of our study was to analyze the mean platelet volume levels as a potential marker of altered placentation in intrauterine growth restriction (IUGR) cases. Methods A total of 126 term singleton pregnant women with IUGR fetuses and 345 healthy pregnant controls were recruited and compared. Results The mean platelet volume was significantly higher in the IUGR group (10.8±0.9 fl) than the control group (9.9±1.1 fl) (p=0.03). The mean hemoglobin was lower in IUGR group (11.3 (8.3–14.5) g/dl) than the control group (11.9 (8.2–13.0) g/dl) (p=0.04). The optimal cut-off MPV for prediction of IUGR was ≥10.55 fl, with a sensitivity of 59% and a specificity of 75%. Conclusion Increased MPV levels in term pregnant women may be particularly helpful for discrimination and prediction of high-risk fetuses when IUGR is suspected.

scholarly journals The Feasibility and Acceptability of Project POWER: A Cognitive-Behavioral Mindfulness-Infused Group-Based Mental and Sexual Health Intervention Among Young Pregnant Women in Liberia

2021 ◽  
Author(s):  
Tamora A. Callands ◽  
Kandyce Hylick ◽  
Alethea Desrosiers ◽  
Shantesica M. Gilliam ◽  
Erica N. Taylor ◽  
...  
Keyword(s):  
Young Adult ◽  
Sexual Health ◽  
Health Outcomes ◽  
Pregnant Women ◽  
Repeated Measures ◽  
Cognitive Behavioral ◽  
Control Group ◽  
Depression Symptoms ◽  
Adult Women ◽  
Catchment Areas

Abstract Background Following 14 years of civil war in Liberia, war-exposure, gender-based violence, and extreme poverty have been identified as key challenges to the mental and sexual health of young pregnant women, and the health of their unborn children. Despite ongoing efforts to rebuild the country’s healthcare infrastructure, empirical research and interventions focused on addressing the consequences of war on the mental and sexual health of young pregnant women in Liberia are severely limited. To address these concerns, we developed Project POWER (Progressing Our Well-being, Emotions, and Relationships) (POWER), a mindfulness-infused cognitive-behavioral intervention for young adult pregnant women. This study sought to: 1) assess the feasibility and acceptability of POWER; and (2) determine the preliminary efficacy of POWER for improving mental and sexual health outcomes among Liberian war-exposed pregnant young adult women. Methods Eighty-seven women ages 18-25 years were recruited from three catchment areas in Monrovia, Liberia. Participants participated in one of two ten-session programs delivered over 5-weeks: POWER or a control group (a health education program). Feasibility and acceptability of POWER were examined using program log (e.g., the number of participants screened and enrolled, facilitator satisfaction, etc.) data from an exit interview. Results Preliminary efficacy of POWER’s effects on mental and sexual health outcomes was assessed using a series of four one-way repeated measures ANOVA with time and group as predictors. Analyses provided preliminary support for the feasibility and acceptability of POWER. Preliminary efficacy of POWER showed significant reductions in depression symptoms, PTSD symptoms, prenatal distress, and transactional sex over time. Conclusions Findings suggest that POWER may be a feasible and acceptable intervention to promote mental and sexual health for young adult pregnant women in Liberia. Future research is needed to determine the efficacy of POWER on a larger scale in Liberia.

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