scholarly journals Evaluation of a Mobile App to Enhance Relational Awareness and Change During Cognitive Analytic Therapy: Mixed Methods Case Series

10.2196/19888 ◽  
2020 ◽  
Vol 7 (12) ◽  
pp. e19888
Author(s):  
Stephen Kellett ◽  
Katherine Easton ◽  
Martin Cooper ◽  
Abigail Millings ◽  
Melanie Simmonds-Buckley ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Clinical Outcome ◽  
Outcome Measure ◽  
Case Series ◽  
Mobile App ◽  
Significant Difference ◽  
Analytic Therapy ◽  
Evaluation Outcome ◽  
The Relationship ◽  
Cognitive Analytic Therapy

Background There has been a lack of technological innovation regarding improving the delivery of integrative psychotherapies. This project sought to evaluate an app designed to replace previous paper-based methods supporting relational awareness and change during cognitive analytic therapy (CAT). Objective We aimed to assess patients’ and therapists’ experience of using the technology (ie, the “CAT-App”) and to evaluate the relationship between app usage and clinical outcome. Methods The design was a mixed methods case series. Patients completed the Clinical Outcomes in Routine Evaluation-Outcome Measure pre- and post-CAT. Mood data plus the frequency and effectiveness of relational awareness and change were collected via the app. Therapists and patients were interviewed about their experiences using the app. Results Ten patients (treated by 3 therapists) were enrolled; seven completed treatment and 4 had a reliable improvement in their mental health. App usage and mood change did not differ according to clinical outcome, but there was a statistically significant difference in app usage between completers and dropouts. The qualitative themes described by the therapists were (1) the challenge of incorporating the technology into their clinical practice and (2) the barriers and benefits of the technology. Clients’ themes were (1) data protection, (2) motivation and engagement, and (3) restrictions versus flexibility. Conclusions The CAT-App is capable of supporting relational awareness and change and is an upgrade on older, paper-based formats. Further clinical evaluation is required.

scholarly journals Evaluation of a Mobile App to Enhance Relational Awareness and Change During Cognitive Analytic Therapy: Mixed Methods Case Series (Preprint)

2020 ◽  
Author(s):  
Stephen Kellett ◽  
Katherine Easton ◽  
Martin Cooper ◽  
Abigail Millings ◽  
Melanie Simmonds-Buckley ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Clinical Outcome ◽  
Outcome Measure ◽  
Case Series ◽  
Mobile App ◽  
Significant Difference ◽  
Analytic Therapy ◽  
Evaluation Outcome ◽  
The Relationship ◽  
Cognitive Analytic Therapy

BACKGROUND There has been a lack of technological innovation regarding improving the delivery of integrative psychotherapies. This project sought to evaluate an app designed to replace previous paper-based methods supporting relational awareness and change during cognitive analytic therapy (CAT). OBJECTIVE We aimed to assess patients’ and therapists’ experience of using the technology (ie, the “CAT-App”) and to evaluate the relationship between app usage and clinical outcome. METHODS The design was a mixed methods case series. Patients completed the Clinical Outcomes in Routine Evaluation-Outcome Measure pre- and post-CAT. Mood data plus the frequency and effectiveness of relational awareness and change were collected via the app. Therapists and patients were interviewed about their experiences using the app. RESULTS Ten patients (treated by 3 therapists) were enrolled; seven completed treatment and 4 had a reliable improvement in their mental health. App usage and mood change did not differ according to clinical outcome, but there was a statistically significant difference in app usage between completers and dropouts. The qualitative themes described by the therapists were (1) the challenge of incorporating the technology into their clinical practice and (2) the barriers and benefits of the technology. Clients’ themes were (1) data protection, (2) motivation and engagement, and (3) restrictions versus flexibility. CONCLUSIONS The CAT-App is capable of supporting relational awareness and change and is an upgrade on older, paper-based formats. Further clinical evaluation is required.

scholarly journals Correction: Evaluation of a Mobile App to Enhance Relational Awareness and Change During Cognitive Analytic Therapy: Mixed Methods Case Series

10.2196/27159 ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. e27159
Author(s):  
Stephen Kellett ◽  
Katherine Easton ◽  
Martin Cooper ◽  
Abigail Millings ◽  
Melanie Simmonds-Buckley ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Case Series ◽  
Mobile App ◽  
Analytic Therapy ◽  
Cognitive Analytic Therapy

scholarly journals Correction: Evaluation of a Mobile App to Enhance Relational Awareness and Change During Cognitive Analytic Therapy: Mixed Methods Case Series (Preprint)

2021 ◽  
Author(s):  
Stephen Kellett ◽  
Katherine Easton ◽  
Martin Cooper ◽  
Abigail Millings ◽  
Melanie Simmonds-Buckley ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Case Series ◽  
Mobile App ◽  
Analytic Therapy ◽  
Cognitive Analytic Therapy

UNSTRUCTURED REMOVE

scholarly journals Cognitive analytic therapy for obsessive morbid jealousy: A case series.

2018 ◽  
Vol 28 (4) ◽  
pp. 537-555 ◽  
Author(s):  
Louise Curling ◽  
Stephen Kellett ◽  
Peter Totterdell
Keyword(s):  
Case Series ◽  
Analytic Therapy ◽  
Cognitive Analytic Therapy

scholarly journals Evaluation of the relationship between primary spontaneous pneumothorax and exercise and patient return to previous activities in patients after treatment

2021 ◽  
Vol 9 (2) ◽  
pp. 008-014
Author(s):  
Rastin Hosseinzadeh Asli ◽  
Manouchehr Aghajanzadeh ◽  
Hossein Hosseinzadeh Asli ◽  
Yousha poorahmadi
Keyword(s):  
Spontaneous Pneumothorax ◽  
Clinical Manifestations ◽  
Case Series ◽  
Tube Thoracostomy ◽  
Primary Spontaneous Pneumothorax ◽  
Chi Square ◽  
Exercise Time ◽  
Exact Test ◽  
Significant Difference ◽  
The Relationship

Introduction: The most common cause of primary spontaneous pneumothorax (PSP) is sub pleural bleb apical rupture. Little is known about the relationship between PSP and exercise and return to exercise time. In this study, wee tend to investigate the relationship between exercise and PSP and time of return to exercise and previous activities. Method: This study was designed as a case series and the sample size included all patients diagnosed with PSP in Razi and Poursina and Aria hospitals of Rasht during 2015-2019 based on inclusion criteria. Variables were analyzed using Fisher's exact test, Chi square, Mann Whitney U and t-test (p<0.05). Results: The most common type of treatment in patients was transaxillary thoracotomy with pleurodesis with iodine (TTP) in 58.2% and tube thoracostomy and pleurodesis in 41.7%, which was not statistically significant between athletes and non-athletes (p=0.806). Athletes who underwent TTP after 4 weeks and those treated with tube thoracostomy and pleurodesis after 8-12 weeks were advised to return to their previous activity. Of athletes, 9.5% had recurrence; of non-athletes, 9.8% had recurrence. Of athletes, 4.8% did not tolerate a return to their previous activity; of non-athletes, 7.3% did not tolerate returning to their previous activity regardless of treatment, and this difference was not significant. Conclusion: Our study showed no significant difference between clinical manifestations and image findings as well as frequency of treatment and complications in both athlete and non-athlete patients. There is no increase in recurrence and intolerance at the time recommended for return to previous activity.

scholarly journals Comparing the Effectiveness of Mentalization-Based Therapy and Cognitive-Analytic Therapy on Ego Strength and Defense Mechanisms in People With Borderline Personality Disorder

2019 ◽  
Vol 25 (4) ◽  
pp. 324-339
Author(s):  
Sanaz Einy ◽  
◽  
Mohammad Narimani‎ ◽  
Fariba Sadeghi Movahhed‎3 ◽  
◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Defense Mechanisms ◽  
Borderline Personality ◽  
Control Group ◽  
Ego Strength ◽  
Significant Difference ◽  
Analytic Therapy ◽  
Experimental Group ◽  
Cognitive Analytic Therapy

Aims Mentalization-Based Therapy (MBT) and Cognitive Analytic Therapy (CAT) are psychotherapy approaches offering specific methods for the treatment of Borderline Personality Disorder (BPD). Therefore, this study compared the effectiveness of MBT and CAT on improving the ego strength and defense mechanisms in people with BPD. Methods & Materials This was a quasi-experimental study with a pretest-posttest and a control group design and follow-up stage. In total, 40 men with BPD were selected by purposive sampling technique. The samples were selected from males admitted to Isar psychiatric Hospital and the psychiatric department of Fatemi Hospital in Ardabil City, Iran, in 2018. The samples were randomly assigned into two experimental groups and one control group. The first experimental group received 20 sessions of MBT, and the second experimental group received 16 sessions of CAT. To collect data, we used psychological inventory ego strength and defense styles questionnaire. The obtained data were analyzed using mixed model Analysis of Variance (ANOVA) and Scheffe posthoc test. Findings The collected results suggested that both interventions were effective in improving the ego strength and defense mechanisms of people with BPD (P<0.001). However, the effect of MBT on the overall score of the ego strength and the immature defenses was higher than that of the other intervention (P<0.05). Moreover, there was no significant difference in neurotic defense between the two interventions (P>0.05). Conclusion The present research results can support the use of these therapies as part of a non-pharmaceutical treatment program in different treatment centers or psychiatric hospitals.

Clinical Outcome Routine Evaluation--Outcome Measure; Italian Version

2009 ◽  
Author(s):  
Gaspare Palmieri ◽  
Chris Evans ◽  
Vidje Hansen ◽  
Greta Brancaleoni ◽  
Silvia Ferrari ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Outcome Measure ◽  
Italian Version ◽  
Evaluation Outcome

Circulating CD2 Negative T Cells in Pediatric Acute Leukemia

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 5151-5151
Author(s):  
Weijie Li ◽  
Lei Shao ◽  
Atif Ahmed ◽  
Doug Myers ◽  
Keith J August
Keyword(s):  
T Cells ◽  
T Cell ◽  
Clinical Outcome ◽  
Peripheral Blood ◽  
Gene Rearrangement ◽  
Control Group ◽  
Future Studies ◽  
Significant Difference ◽  
Relationship Of ◽  
The Relationship

Abstract Introduction: Leukemia cells are able to escape from immunosurveillance using immune tolerance mechanisms as the majority of leukemia antigens are either shared or aberrantly expressed self-proteins. T cells reactive to these antigens are purged during thymic selection. CD2, a pan-T-cell antigen, is expressed early during T cell developments in thymus and is found on all subsets of mature T cells. Recent studies show that there are low levels of extrathymic CD2 negative (CD2-) T cells, which show immature T cell features and can be induced to differentiate into mature helper and cytotoxic T cells in vitro. Since circulating CD2- T cells could represent pre-selection immature T cells, they may play an important role in tumor immunity. Methods: 81 pediatric B-cell acute lymphoblastic leukemia (B-ALL) patients, 22 pediatric acute myeloid leukemia (AML) patients and 22 normal controls were included in this study. B-ALL group included 45 NCI-standard risk (SR) patients and 36 NCI-high risk patients. All the leukemia patients were diagnosed at Children's Mercy Hospital in the past ten years with a diagnostic peripheral blood (PB) specimen. The PB specimens were studied by four-color multiparameter flow cytometry with antibodies for T cell markers (CD2, CD3, CD4, CD5, CD7 and CD8) and CD45, and analyzed by BD FACSDiva 8.0.1. CD2- and CD3+ T cells were recorded as % of total T cells. Student's t-test was used to compare results. Results: The percentages of CD2- T cells in AML (mean ± STD: 1.31% ± 1.41%) and B-ALL (0.84% ± 0.67%) were significantly higher than that seen in control group (0.51% ± 0.52%, p<0.05). No significant difference was found between AML and B-ALL. There was no significant difference between HR B-ALL (0.96% ± 0.81%) and SR B-ALL (0.74% ± 0.52%). Interestingly, CD2- T cells in 4/5 B-ALLs with 11q23 (KMT2A) rearrangement were undetectable. All 3 therapy-related AML patients studied had KMT2A gene rearrangement, and had no detectable CD2- T cells with poor clinical outcome (overall survival less than 1 year). The 3 AMLs associated with Down syndrome, a prognostically favorable AML group, showed relative high levels (≥ 1.49%) of CD2- T cells. Conclusions: Circulating CD2- T cells are increased in peripheral blood in pediatric AML and B-ALL patients. KMT2A gene rearrangement, an unfavorable cytogenetic abnormality, is associated with a decrease in CD2- T cells. The relationship of KMT2A gene rearrangement and decrease in circulating CD2- T-cells as well as the relationship of CD2- T cells to clinical outcome should be evaluated in future studies. The role of CD2- T cells in tumor specific immunomodulation should be explored, and may impact future studies of cell-based cancer immunotherapeutics. Disclosures No relevant conflicts of interest to declare.

scholarly journals Early intervention for adolescents with borderline personality disorder using cognitive analytic therapy: randomised controlled trial

2008 ◽  
Vol 193 (6) ◽  
pp. 477-484 ◽  
Author(s):  
Andrew M. Chanen ◽  
Henry J. Jackson ◽  
Louise K. McCutcheon ◽  
Martina Jovev ◽  
Paul Dudgeon ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Randomised Controlled Trial ◽  
Personality Disorder ◽  
Controlled Trial ◽  
Borderline Personality ◽  
Global Functioning ◽  
Significant Difference ◽  
Analytic Therapy ◽  
Randomised Controlled ◽  
Cognitive Analytic Therapy

BackgroundNo accepted intervention exists for borderline personality disorder presenting in adolescence.AimsTo compare the effectiveness of up to 24 sessions of cognitive analytic therapy (CAT) or manualised good clinical care (GCC) in addition to a comprehensive service model of care.MethodIn a randomised controlled trial, CAT and GCC were compared in out-patients aged 15–18 years who fulfilled two to nine of the DSM–IV criteria for borderline personality disorder. We predicted that, compared with the GCC group, the CAT group would show greater reductions in psychopathology and parasuicidal behaviour and greater improvement in global functioning over 24 months.ResultsEighty-six patients were randomised and 78 (CAT n=41; GCC n=37) provided follow-up data. There was no significant difference between the outcomes of the treatment groups at 24 months on the pre-chosen measures but there was some evidence that patients allocated to CAT improved more rapidly. No adverse effect was shown with either treatment.ConclusionsBoth CAT and GCC are effective in reducing externalising psychopathology in teenagers with sub-syndromal or full-syndrome bipolar personality disorder. Larger studies are required to determine the specific value of CAT in this population.

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