scholarly journals Study of Treatment and Reproductive Outcomes (STAR): A Protocol for a Longitudinal Cohort Study of HIV Infection and Treatment among Women of Reproductive Age in the Southern United States (Preprint)

10.2196/30398 ◽  
2021 ◽  
Author(s):  
Anandi N. Sheth ◽  
Adaora A. Adimora ◽  
Elizabeth Topper Golub ◽  
Seble G. Kassaye ◽  
Aadia Rana ◽  
...  
2021 ◽  
Vol 38 (5) ◽  
pp. 6-14
Author(s):  
A. O. Ovchinnikova ◽  
S. V. Mikhalchenko ◽  
M. A. Kaganova ◽  
O. E. Chernova

Objective. To assess the levels of viral load, immune status as well as labor outcome depending on the absence or presence of pregravid preparation with the partner and without the latter. Materials and methods. This cohort study included 90 women of reproductive age with stages 3 and 4A HIV infection. To compare the groups, Kruskal Wallis, Mann Whitney tests and correlation analysis were applied. Results. The pregravid preparation of HIV-infected women without a partner was detected to three-fold decrease a viral load in the I trimester of pregnancy (p = 0.001), two-fold in the II trimester (p = 0.02) and three-fold in the III trimester (p = 0.002); with a partner a two-fold decrease in the I trimester (p = 0.0018). The pregravid preparation of HIV-infected women reduces the probability of giving birth to a child with low body mass (p = 0.023); with a partner it decreases the risk for the preterm labor (p = 0.02). Conclusions. Thus, the presence of pregravid preparation in HIV-infected women, with a partner as well, decreases the probability of giving birth to a child with low body mass and preterm labor.


2018 ◽  
Vol 19 (7) ◽  
pp. 633-638 ◽  
Author(s):  
Aline De Vleminck ◽  
R. Sean Morrison ◽  
Diane E. Meier ◽  
Melissa D. Aldridge

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