Digital Interventions for Cardiac Rehabilitation: A Systematic Literature Review (Preprint)
BACKGROUND Cardiovascular disease (CVD) is the leading cause of death worldwide. Despite strong evidence supporting the benefits of cardiac rehabilitation (CR), over 80% of eligible patients do not participate. Digital health technologies (i.e. the delivery of care through the use of the internet, wearable devices, and mobile applications) have the potential to address the challenges associated with traditional facility-based CR programs but little is known about the comprehensiveness of these interventions to serve as digital approaches to CR. Overall, a systematic evaluation of the current literature on digital interventions for CR is lacking. OBJECTIVE The objective of this systematic literature review is to provide an in-depth analysis of the potential for digital health technologies to address the challenges associated with traditional CR. Through this review, we 1) summarize the current literature on digital interventions for CR, 2) identify the key components of CR that have been successfully addressed through digital interventions, and 3) describe gaps in research that need to be addressed for sustainable and scalable digital CR interventions. METHODS Our search strategy for identifying primary literature pertaining to CR with digital solutions (defined as technology employed to deliver remote care beyond the use of telephone) consisted of querying MEDLINE, Embase, CINAHL, and Cochrane databases for original studies published from January 1990 to October 2018 and consulting with an expert in the field of digital CR. RESULTS Our search returned 31 eligible studies, of which 22 were randomized controlled trials. The CR interventions reviewed primarily targeted physical activity counseling (100%; n=31), baseline assessment (97%; n=30) and exercise training (87%; n=27). The most common modalities used were smartphone/mobile devices (65%; n=20), online portals (58%; n=18), and email-SMS (35%; n=11). Approximately one third of studies addressed the CR core components of nutrition counseling, psychological management, and weight management. In contrast, less than a third of the studies addressed other CR core components including management of lipids, diabetes, smoking cessation, and blood pressure. CONCLUSIONS Digital technologies have the potential to increase access and participation in CR by mitigating the challenges associated with traditional, facility-based CR. However, interventions that have previously been evaluated are primarily focused on physical activity counseling and exercise training without the other core components of CR. Thus, further research is required with more comprehensive CR interventions and long-term follow-up in order to understand the clinical impact of digital interventions. CLINICALTRIAL